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    Eef1g eukaryotic translation elongation factor 1 gamma [ Mus musculus (house mouse) ]

    Gene ID: 67160, updated on 2-Nov-2024

    Summary

    Official Symbol
    Eef1gprovided by MGI
    Official Full Name
    eukaryotic translation elongation factor 1 gammaprovided by MGI
    Primary source
    MGI:MGI:1914410
    See related
    Ensembl:ENSMUSG00000071644 AllianceGenome:MGI:1914410
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    EF1G; 2610301D06Rik
    Summary
    Predicted to enable translation elongation factor activity. Predicted to be involved in translational elongation. Predicted to be active in cytoplasm and nucleus. Predicted to colocalize with endoplasmic reticulum. Is expressed in 2nd branchial arch; 3rd branchial pouch; and early conceptus. Orthologous to human EEF1G (eukaryotic translation elongation factor 1 gamma). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Ubiquitous expression in CNS E11.5 (RPKM 183.6), testis adult (RPKM 170.4) and 28 other tissues See more
    Orthologs
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    Genomic context

    See Eef1g in Genome Data Viewer
    Location:
    19 A; 19 6.04 cM
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 19 NC_000085.7 (8944405..8955544)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 19 NC_000085.6 (8967041..8978180)

    Chromosome 19 - NC_000085.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E5684 Neighboring gene predicted gene 10353 Neighboring gene STARR-positive B cell enhancer ABC_E11018 Neighboring gene metastasis-associated gene family, member 2 Neighboring gene STARR-positive B cell enhancer ABC_E3241 Neighboring gene CapStarr-seq enhancer MGSCv37_chr19:9041491-9041707 Neighboring gene terminal uridylyl transferase 1, U6 snRNA-specific Neighboring gene STARR-positive B cell enhancer ABC_E3242 Neighboring gene CapStarr-seq enhancer MGSCv37_chr19:9072131-9072314 Neighboring gene AHNAK nucleoprotein Neighboring gene STARR-positive B cell enhancer ABC_E5685 Neighboring gene secretoglobin, family 1A, member 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (2) 

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Clone Names

    • MGC103354, MGC144723, MGC144724

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables translation elongation factor activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in response to virus IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in translational elongation IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in translational elongation IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in endoplasmic reticulum IEA
    Inferred from Electronic Annotation
    more info
     
    colocalizes_with endoplasmic reticulum ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    elongation factor 1-gamma
    Names
    EF-1-gamma
    eEF-1B gamma

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_026007.4NP_080283.3  elongation factor 1-gamma

      See identical proteins and their annotated locations for NP_080283.3

      Status: VALIDATED

      Source sequence(s)
      AK145519
      Consensus CDS
      CCDS29563.1
      UniProtKB/Swiss-Prot
      Q920C5, Q9CRT5, Q9CSU3, Q9D004, Q9D8N0
      UniProtKB/TrEMBL
      Q4FZK2
      Related
      ENSMUSP00000093955.5, ENSMUST00000052248.8
      Conserved Domains (5) summary
      cd03181
      Location:91213
      GST_C_EF1Bgamma_like; Glutathione S-transferase C-terminal-like, alpha helical domain of the Gamma subunit of Elongation Factor 1B and similar proteins
      COG0625
      Location:5202
      GstA; Glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]
      cd03044
      Location:482
      GST_N_EF1Bgamma; GST_N family, Gamma subunit of Elongation Factor 1B (EFB1gamma) subfamily; EF1Bgamma is part of the eukaryotic translation elongation factor-1 (EF1) complex which plays a central role in the elongation cycle during protein biosynthesis. EF1 consists of ...
      pfam00647
      Location:275381
      EF1G; Elongation factor 1 gamma, conserved domain
      cl15270
      Location:211265
      FinO_conjug_rep; FinO bacterial conjugation repressor domain; the basic protein FinO is part of the the two component FinOP system which is responsible for repressing bacterial conjugation; the FinOP system represses the transfer (tra) operon of the F-plasmid which ...

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000085.7 Reference GRCm39 C57BL/6J

      Range
      8944405..8955544
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)