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    NR1H4 nuclear receptor subfamily 1 group H member 4 [ Canis lupus familiaris (dog) ]

    Gene ID: 612928, updated on 17-Aug-2024

    Summary

    Official Symbol
    NR1H4provided by VGNC
    Official Full Name
    nuclear receptor subfamily 1 group H member 4provided by VGNC
    Primary source
    VGNC:VGNC:43944
    See related
    Ensembl:ENSCAFG00845006398
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Orthologs
    NEW
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    Genomic context

    See NR1H4 in Genome Data Viewer
    Location:
    chromosome: 15
    Exon count:
    16
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 15 NC_051819.1 (40161103..40272109)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 15 NC_006597.4 (39876387..39987365)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 15 NC_049236.1 (39799183..39910169)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 15 NC_049275.1 (39418531..39529420)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 15 NC_049756.1 (39525061..39636033)

    Chromosome 15 - NC_051819.1Genomic Context describing neighboring genes Neighboring gene SCY1 like pseudokinase 2 Neighboring gene solute carrier family 17 member 8 Neighboring gene uncharacterized LOC119868497 Neighboring gene uncharacterized LOC119881749 Neighboring gene protein lin-28 homolog A-like Neighboring gene growth arrest specific 2 like 3 Neighboring gene anoctamin 4

    Genomic regions, transcripts, and products

    Pathways from PubChem

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051819.1 Reference ROS_Cfam_1.0

      Range
      40161103..40272109
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038688387.1XP_038544315.1  bile acid receptor isoform X4

      UniProtKB/TrEMBL
      A0A8I3RTA2
      Related
      ENSCAFP00845008869.1, ENSCAFT00845011357.1
      Conserved Domains (2) summary
      cd06936
      Location:247467
      NR_LBD_Fxr; The ligand binding domain of Farnesoid X receptor:a member of the nuclear receptor superfamily of ligand-activated transcription factors
      cd06962
      Location:124207
      NR_DBD_FXR; DNA-binding domain of Farnesoid X receptor (FXR) family is composed of two C4-type zinc fingers
    2. XM_038688386.1XP_038544314.1  bile acid receptor isoform X3

      UniProtKB/TrEMBL
      A0A8C0LJE0, A0A8C0S616, A0A8P0STP9
      Conserved Domains (2) summary
      cd06936
      Location:251471
      NR_LBD_Fxr; The ligand binding domain of Farnesoid X receptor:a member of the nuclear receptor superfamily of ligand-activated transcription factors
      cd06962
      Location:124211
      NR_DBD_FXR; DNA-binding domain of Farnesoid X receptor (FXR) family is composed of two C4-type zinc fingers
    3. XM_038688382.1XP_038544310.1  bile acid receptor isoform X3

      UniProtKB/TrEMBL
      A0A8C0LJE0, A0A8C0S616, A0A8P0STP9
      Conserved Domains (2) summary
      cd06936
      Location:251471
      NR_LBD_Fxr; The ligand binding domain of Farnesoid X receptor:a member of the nuclear receptor superfamily of ligand-activated transcription factors
      cd06962
      Location:124211
      NR_DBD_FXR; DNA-binding domain of Farnesoid X receptor (FXR) family is composed of two C4-type zinc fingers
    4. XM_038688384.1XP_038544312.1  bile acid receptor isoform X3

      UniProtKB/TrEMBL
      A0A8C0LJE0, A0A8C0S616, A0A8P0STP9
      Conserved Domains (2) summary
      cd06936
      Location:251471
      NR_LBD_Fxr; The ligand binding domain of Farnesoid X receptor:a member of the nuclear receptor superfamily of ligand-activated transcription factors
      cd06962
      Location:124211
      NR_DBD_FXR; DNA-binding domain of Farnesoid X receptor (FXR) family is composed of two C4-type zinc fingers
    5. XM_038688385.1XP_038544313.1  bile acid receptor isoform X3

      UniProtKB/TrEMBL
      A0A8C0LJE0, A0A8C0S616, A0A8P0STP9
      Conserved Domains (2) summary
      cd06936
      Location:251471
      NR_LBD_Fxr; The ligand binding domain of Farnesoid X receptor:a member of the nuclear receptor superfamily of ligand-activated transcription factors
      cd06962
      Location:124211
      NR_DBD_FXR; DNA-binding domain of Farnesoid X receptor (FXR) family is composed of two C4-type zinc fingers
    6. XM_038688383.1XP_038544311.1  bile acid receptor isoform X3

      UniProtKB/TrEMBL
      A0A8C0LJE0, A0A8C0S616, A0A8P0STP9
      Conserved Domains (2) summary
      cd06936
      Location:251471
      NR_LBD_Fxr; The ligand binding domain of Farnesoid X receptor:a member of the nuclear receptor superfamily of ligand-activated transcription factors
      cd06962
      Location:124211
      NR_DBD_FXR; DNA-binding domain of Farnesoid X receptor (FXR) family is composed of two C4-type zinc fingers
    7. XM_038688380.1XP_038544308.1  bile acid receptor isoform X1

      UniProtKB/TrEMBL
      A0A8C0R707, A0A8C0S6D2
      Conserved Domains (2) summary
      cd06936
      Location:260480
      NR_LBD_Fxr; The ligand binding domain of Farnesoid X receptor:a member of the nuclear receptor superfamily of ligand-activated transcription factors
      cl02596
      Location:133220
      NR_DBD_like; DNA-binding domain of nuclear receptors is composed of two C4-type zinc fingers
    8. XM_038688381.1XP_038544309.1  bile acid receptor isoform X2

      UniProtKB/TrEMBL
      A0A8I3N2S7, A0A8P0N9A5
      Related
      ENSCAFP00845008917.1, ENSCAFT00845011416.1
      Conserved Domains (2) summary
      cd06936
      Location:256476
      NR_LBD_Fxr; The ligand binding domain of Farnesoid X receptor:a member of the nuclear receptor superfamily of ligand-activated transcription factors
      cd06962
      Location:133216
      NR_DBD_FXR; DNA-binding domain of Farnesoid X receptor (FXR) family is composed of two C4-type zinc fingers

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049275.1 Alternate UMICH_Zoey_3.1

      Range
      39418531..39529420
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038496396.1XP_038352324.1  bile acid receptor isoform X4

      Conserved Domains (2) summary
      cd06936
      Location:247467
      NR_LBD_Fxr; The ligand binding domain of Farnesoid X receptor:a member of the nuclear receptor superfamily of ligand-activated transcription factors
      cd06962
      Location:124207
      NR_DBD_FXR; DNA-binding domain of Farnesoid X receptor (FXR) family is composed of two C4-type zinc fingers
    2. XM_038496395.1XP_038352323.1  bile acid receptor isoform X3

      Conserved Domains (2) summary
      cd06936
      Location:251471
      NR_LBD_Fxr; The ligand binding domain of Farnesoid X receptor:a member of the nuclear receptor superfamily of ligand-activated transcription factors
      cd06962
      Location:124211
      NR_DBD_FXR; DNA-binding domain of Farnesoid X receptor (FXR) family is composed of two C4-type zinc fingers
    3. XM_038496391.1XP_038352319.1  bile acid receptor isoform X3

      Conserved Domains (2) summary
      cd06936
      Location:251471
      NR_LBD_Fxr; The ligand binding domain of Farnesoid X receptor:a member of the nuclear receptor superfamily of ligand-activated transcription factors
      cd06962
      Location:124211
      NR_DBD_FXR; DNA-binding domain of Farnesoid X receptor (FXR) family is composed of two C4-type zinc fingers
    4. XM_038496393.1XP_038352321.1  bile acid receptor isoform X3

      Conserved Domains (2) summary
      cd06936
      Location:251471
      NR_LBD_Fxr; The ligand binding domain of Farnesoid X receptor:a member of the nuclear receptor superfamily of ligand-activated transcription factors
      cd06962
      Location:124211
      NR_DBD_FXR; DNA-binding domain of Farnesoid X receptor (FXR) family is composed of two C4-type zinc fingers
    5. XM_038496394.1XP_038352322.1  bile acid receptor isoform X3

      Conserved Domains (2) summary
      cd06936
      Location:251471
      NR_LBD_Fxr; The ligand binding domain of Farnesoid X receptor:a member of the nuclear receptor superfamily of ligand-activated transcription factors
      cd06962
      Location:124211
      NR_DBD_FXR; DNA-binding domain of Farnesoid X receptor (FXR) family is composed of two C4-type zinc fingers
    6. XM_038496392.1XP_038352320.1  bile acid receptor isoform X3

      Conserved Domains (2) summary
      cd06936
      Location:251471
      NR_LBD_Fxr; The ligand binding domain of Farnesoid X receptor:a member of the nuclear receptor superfamily of ligand-activated transcription factors
      cd06962
      Location:124211
      NR_DBD_FXR; DNA-binding domain of Farnesoid X receptor (FXR) family is composed of two C4-type zinc fingers
    7. XM_038496389.1XP_038352317.1  bile acid receptor isoform X1

      Conserved Domains (2) summary
      cd06936
      Location:260480
      NR_LBD_Fxr; The ligand binding domain of Farnesoid X receptor:a member of the nuclear receptor superfamily of ligand-activated transcription factors
      cl02596
      Location:133220
      NR_DBD_like; DNA-binding domain of nuclear receptors is composed of two C4-type zinc fingers
    8. XM_038496390.1XP_038352318.1  bile acid receptor isoform X2

      Conserved Domains (2) summary
      cd06936
      Location:256476
      NR_LBD_Fxr; The ligand binding domain of Farnesoid X receptor:a member of the nuclear receptor superfamily of ligand-activated transcription factors
      cd06962
      Location:133216
      NR_DBD_FXR; DNA-binding domain of Farnesoid X receptor (FXR) family is composed of two C4-type zinc fingers

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049756.1 Alternate UNSW_CanFamBas_1.0

      Range
      39525061..39636033
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038622718.1XP_038478646.1  bile acid receptor isoform X3

      Conserved Domains (2) summary
      cd06936
      Location:251471
      NR_LBD_Fxr; The ligand binding domain of Farnesoid X receptor:a member of the nuclear receptor superfamily of ligand-activated transcription factors
      cd06962
      Location:124211
      NR_DBD_FXR; DNA-binding domain of Farnesoid X receptor (FXR) family is composed of two C4-type zinc fingers
    2. XM_038622714.1XP_038478642.1  bile acid receptor isoform X3

      Conserved Domains (2) summary
      cd06936
      Location:251471
      NR_LBD_Fxr; The ligand binding domain of Farnesoid X receptor:a member of the nuclear receptor superfamily of ligand-activated transcription factors
      cd06962
      Location:124211
      NR_DBD_FXR; DNA-binding domain of Farnesoid X receptor (FXR) family is composed of two C4-type zinc fingers
    3. XM_038622719.1XP_038478647.1  bile acid receptor isoform X4

      Conserved Domains (2) summary
      cd06936
      Location:247467
      NR_LBD_Fxr; The ligand binding domain of Farnesoid X receptor:a member of the nuclear receptor superfamily of ligand-activated transcription factors
      cd06962
      Location:124207
      NR_DBD_FXR; DNA-binding domain of Farnesoid X receptor (FXR) family is composed of two C4-type zinc fingers
    4. XM_038622716.1XP_038478644.1  bile acid receptor isoform X3

      Conserved Domains (2) summary
      cd06936
      Location:251471
      NR_LBD_Fxr; The ligand binding domain of Farnesoid X receptor:a member of the nuclear receptor superfamily of ligand-activated transcription factors
      cd06962
      Location:124211
      NR_DBD_FXR; DNA-binding domain of Farnesoid X receptor (FXR) family is composed of two C4-type zinc fingers
    5. XM_038622717.1XP_038478645.1  bile acid receptor isoform X3

      Conserved Domains (2) summary
      cd06936
      Location:251471
      NR_LBD_Fxr; The ligand binding domain of Farnesoid X receptor:a member of the nuclear receptor superfamily of ligand-activated transcription factors
      cd06962
      Location:124211
      NR_DBD_FXR; DNA-binding domain of Farnesoid X receptor (FXR) family is composed of two C4-type zinc fingers
    6. XM_038622715.1XP_038478643.1  bile acid receptor isoform X3

      Conserved Domains (2) summary
      cd06936
      Location:251471
      NR_LBD_Fxr; The ligand binding domain of Farnesoid X receptor:a member of the nuclear receptor superfamily of ligand-activated transcription factors
      cd06962
      Location:124211
      NR_DBD_FXR; DNA-binding domain of Farnesoid X receptor (FXR) family is composed of two C4-type zinc fingers
    7. XM_038622712.1XP_038478640.1  bile acid receptor isoform X1

      Conserved Domains (2) summary
      cd06936
      Location:260480
      NR_LBD_Fxr; The ligand binding domain of Farnesoid X receptor:a member of the nuclear receptor superfamily of ligand-activated transcription factors
      cl02596
      Location:133220
      NR_DBD_like; DNA-binding domain of nuclear receptors is composed of two C4-type zinc fingers
    8. XM_038622713.1XP_038478641.1  bile acid receptor isoform X2

      Conserved Domains (2) summary
      cd06936
      Location:256476
      NR_LBD_Fxr; The ligand binding domain of Farnesoid X receptor:a member of the nuclear receptor superfamily of ligand-activated transcription factors
      cd06962
      Location:133216
      NR_DBD_FXR; DNA-binding domain of Farnesoid X receptor (FXR) family is composed of two C4-type zinc fingers

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049236.1 Alternate UU_Cfam_GSD_1.0

      Range
      39799183..39910169
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038558798.1XP_038414726.1  bile acid receptor isoform X4

      UniProtKB/TrEMBL
      A0A8I3RTA2
      Conserved Domains (2) summary
      cd06936
      Location:247467
      NR_LBD_Fxr; The ligand binding domain of Farnesoid X receptor:a member of the nuclear receptor superfamily of ligand-activated transcription factors
      cd06962
      Location:124207
      NR_DBD_FXR; DNA-binding domain of Farnesoid X receptor (FXR) family is composed of two C4-type zinc fingers
    2. XM_038558797.1XP_038414725.1  bile acid receptor isoform X3

      UniProtKB/TrEMBL
      A0A8C0LJE0, A0A8C0S616, A0A8P0STP9
      Conserved Domains (2) summary
      cd06936
      Location:251471
      NR_LBD_Fxr; The ligand binding domain of Farnesoid X receptor:a member of the nuclear receptor superfamily of ligand-activated transcription factors
      cd06962
      Location:124211
      NR_DBD_FXR; DNA-binding domain of Farnesoid X receptor (FXR) family is composed of two C4-type zinc fingers
    3. XM_038558793.1XP_038414721.1  bile acid receptor isoform X3

      UniProtKB/TrEMBL
      A0A8C0LJE0, A0A8C0S616, A0A8P0STP9
      Conserved Domains (2) summary
      cd06936
      Location:251471
      NR_LBD_Fxr; The ligand binding domain of Farnesoid X receptor:a member of the nuclear receptor superfamily of ligand-activated transcription factors
      cd06962
      Location:124211
      NR_DBD_FXR; DNA-binding domain of Farnesoid X receptor (FXR) family is composed of two C4-type zinc fingers
    4. XM_038558795.1XP_038414723.1  bile acid receptor isoform X3

      UniProtKB/TrEMBL
      A0A8C0LJE0, A0A8C0S616, A0A8P0STP9
      Conserved Domains (2) summary
      cd06936
      Location:251471
      NR_LBD_Fxr; The ligand binding domain of Farnesoid X receptor:a member of the nuclear receptor superfamily of ligand-activated transcription factors
      cd06962
      Location:124211
      NR_DBD_FXR; DNA-binding domain of Farnesoid X receptor (FXR) family is composed of two C4-type zinc fingers
    5. XM_038558796.1XP_038414724.1  bile acid receptor isoform X3

      UniProtKB/TrEMBL
      A0A8C0LJE0, A0A8C0S616, A0A8P0STP9
      Conserved Domains (2) summary
      cd06936
      Location:251471
      NR_LBD_Fxr; The ligand binding domain of Farnesoid X receptor:a member of the nuclear receptor superfamily of ligand-activated transcription factors
      cd06962
      Location:124211
      NR_DBD_FXR; DNA-binding domain of Farnesoid X receptor (FXR) family is composed of two C4-type zinc fingers
    6. XM_038558794.1XP_038414722.1  bile acid receptor isoform X3

      UniProtKB/TrEMBL
      A0A8C0LJE0, A0A8C0S616, A0A8P0STP9
      Conserved Domains (2) summary
      cd06936
      Location:251471
      NR_LBD_Fxr; The ligand binding domain of Farnesoid X receptor:a member of the nuclear receptor superfamily of ligand-activated transcription factors
      cd06962
      Location:124211
      NR_DBD_FXR; DNA-binding domain of Farnesoid X receptor (FXR) family is composed of two C4-type zinc fingers
    7. XM_038558791.1XP_038414719.1  bile acid receptor isoform X1

      UniProtKB/TrEMBL
      A0A8C0R707, A0A8C0S6D2
      Conserved Domains (2) summary
      cd06936
      Location:260480
      NR_LBD_Fxr; The ligand binding domain of Farnesoid X receptor:a member of the nuclear receptor superfamily of ligand-activated transcription factors
      cl02596
      Location:133220
      NR_DBD_like; DNA-binding domain of nuclear receptors is composed of two C4-type zinc fingers
    8. XM_038558792.1XP_038414720.1  bile acid receptor isoform X2

      UniProtKB/TrEMBL
      A0A8I3N2S7, A0A8P0N9A5
      Conserved Domains (2) summary
      cd06936
      Location:256476
      NR_LBD_Fxr; The ligand binding domain of Farnesoid X receptor:a member of the nuclear receptor superfamily of ligand-activated transcription factors
      cd06962
      Location:133216
      NR_DBD_FXR; DNA-binding domain of Farnesoid X receptor (FXR) family is composed of two C4-type zinc fingers

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006597.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      39876387..39987365
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038450621.1XP_038306549.1  bile acid receptor isoform X4

      UniProtKB/TrEMBL
      A0A8I3RTA2
      Conserved Domains (2) summary
      cd06936
      Location:247467
      NR_LBD_Fxr; The ligand binding domain of Farnesoid X receptor:a member of the nuclear receptor superfamily of ligand-activated transcription factors
      cd06962
      Location:124207
      NR_DBD_FXR; DNA-binding domain of Farnesoid X receptor (FXR) family is composed of two C4-type zinc fingers
    2. XM_038450614.1XP_038306542.1  bile acid receptor isoform X3

      UniProtKB/TrEMBL
      A0A8C0LJE0, A0A8C0S616, A0A8P0STP9
      Conserved Domains (2) summary
      cd06936
      Location:251471
      NR_LBD_Fxr; The ligand binding domain of Farnesoid X receptor:a member of the nuclear receptor superfamily of ligand-activated transcription factors
      cd06962
      Location:124211
      NR_DBD_FXR; DNA-binding domain of Farnesoid X receptor (FXR) family is composed of two C4-type zinc fingers
    3. XM_038450578.1XP_038306506.1  bile acid receptor isoform X3

      UniProtKB/TrEMBL
      A0A8C0LJE0, A0A8C0S616, A0A8P0STP9
      Conserved Domains (2) summary
      cd06936
      Location:251471
      NR_LBD_Fxr; The ligand binding domain of Farnesoid X receptor:a member of the nuclear receptor superfamily of ligand-activated transcription factors
      cd06962
      Location:124211
      NR_DBD_FXR; DNA-binding domain of Farnesoid X receptor (FXR) family is composed of two C4-type zinc fingers
    4. XM_022403402.2XP_022259110.1  bile acid receptor isoform X3

      UniProtKB/TrEMBL
      A0A8C0LJE0, A0A8C0S616, A0A8P0STP9
      Conserved Domains (2) summary
      cd06936
      Location:251471
      NR_LBD_Fxr; The ligand binding domain of Farnesoid X receptor:a member of the nuclear receptor superfamily of ligand-activated transcription factors
      cd06962
      Location:124211
      NR_DBD_FXR; DNA-binding domain of Farnesoid X receptor (FXR) family is composed of two C4-type zinc fingers
    5. XM_038450605.1XP_038306533.1  bile acid receptor isoform X3

      UniProtKB/TrEMBL
      A0A8C0LJE0, A0A8C0S616, A0A8P0STP9
      Conserved Domains (2) summary
      cd06936
      Location:251471
      NR_LBD_Fxr; The ligand binding domain of Farnesoid X receptor:a member of the nuclear receptor superfamily of ligand-activated transcription factors
      cd06962
      Location:124211
      NR_DBD_FXR; DNA-binding domain of Farnesoid X receptor (FXR) family is composed of two C4-type zinc fingers
    6. XM_847866.6XP_852959.2  bile acid receptor isoform X3

      UniProtKB/TrEMBL
      A0A8C0LJE0, A0A8C0S616, A0A8P0STP9
      Conserved Domains (2) summary
      cd06936
      Location:251471
      NR_LBD_Fxr; The ligand binding domain of Farnesoid X receptor:a member of the nuclear receptor superfamily of ligand-activated transcription factors
      cd06962
      Location:124211
      NR_DBD_FXR; DNA-binding domain of Farnesoid X receptor (FXR) family is composed of two C4-type zinc fingers
    7. XM_861529.5XP_866622.2  bile acid receptor isoform X1

      UniProtKB/TrEMBL
      A0A8C0R707, A0A8C0S6D2
      Conserved Domains (2) summary
      cd06936
      Location:260480
      NR_LBD_Fxr; The ligand binding domain of Farnesoid X receptor:a member of the nuclear receptor superfamily of ligand-activated transcription factors
      cl02596
      Location:133220
      NR_DBD_like; DNA-binding domain of nuclear receptors is composed of two C4-type zinc fingers
    8. XM_005629274.3XP_005629331.1  bile acid receptor isoform X2

      UniProtKB/TrEMBL
      A0A8I3N2S7, A0A8P0N9A5
      Conserved Domains (2) summary
      cd06936
      Location:256476
      NR_LBD_Fxr; The ligand binding domain of Farnesoid X receptor:a member of the nuclear receptor superfamily of ligand-activated transcription factors
      cd06962
      Location:133216
      NR_DBD_FXR; DNA-binding domain of Farnesoid X receptor (FXR) family is composed of two C4-type zinc fingers