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    ALDH4A1 aldehyde dehydrogenase 4 family member A1 [ Canis lupus familiaris (dog) ]

    Gene ID: 612452, updated on 17-Aug-2024

    Summary

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    Official Symbol
    ALDH4A1provided by VGNC
    Official Full Name
    aldehyde dehydrogenase 4 family member A1provided by VGNC
    Primary source
    VGNC:VGNC:111335
    See related
    Ensembl:ENSCAFG00845003681
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Orthologs
    human mouse all
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    Genomic context

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    See ALDH4A1 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 2 NC_051806.1 (80311305..80335987)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 2 NC_006584.4 (76202258..76226797)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 2 NC_049223.1 (79151584..79176100)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 2 NC_049262.1 (77070827..77093559)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 2 NC_049743.1 (78080932..78105430)

    Chromosome 2 - NC_051806.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC119870470 Neighboring gene intermediate filament family orphan 2 Neighboring gene taste 1 receptor member 2 Neighboring gene uncharacterized LOC119870058

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Light-activated BioID - an optically activated proximity labeling system to study protein-protein interactions. Shafraz O, et al. J Cell Sci, 2023 Oct 1. PMID 37756605, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables 1-pyrroline-5-carboxylate dehydrogenase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in proline catabolic process to glutamate IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial; LOW QUALITY PROTEIN: delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial
    XP_038326865.1
    XP_038387741.1
    XP_038451999.1
    XP_038516083.1
    XP_855272.2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051806.1 Reference ROS_Cfam_1.0

      Range
      80311305..80335987
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      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038660155.1 → XP_038516083.1  LOW QUALITY PROTEIN: delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial isoform X1

      UniProtKB/TrEMBL
      A0A8C0RVF5
      Related
      ENSCAFP00845005261.1, ENSCAFT00845006611.1
      Conserved Domains (1) summary
      cd07123
      Location:37 → 558
      ALDH_F4-17_P5CDH; Delta(1)-pyrroline-5-carboxylate dehydrogenase, ALDH families 4 and 17

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049262.1 Alternate UMICH_Zoey_3.1

      Range
      77070827..77093559
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038470937.1 → XP_038326865.1  LOW QUALITY PROTEIN: delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial isoform X2

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049743.1 Alternate UNSW_CanFamBas_1.0

      Range
      78080932..78105430
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038596071.1 → XP_038451999.1  delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial isoform X1

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049223.1 Alternate UU_Cfam_GSD_1.0

      Range
      79151584..79176100
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038531813.1 → XP_038387741.1  delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial isoform X1

      UniProtKB/TrEMBL
      A0A8C0JX29, A0A8C0RVF5

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006584.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      76202258..76226797
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_850179.6 → XP_855272.2  delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial isoform X1

      UniProtKB/TrEMBL
      A0A8C0N6F0, A0A8C0RVF5, A0A8P0NR41
      Conserved Domains (1) summary
      cd07123
      Location:33 → 554
      ALDH_F4-17_P5CDH; Delta(1)-pyrroline-5-carboxylate dehydrogenase, ALDH families 4 and 17
    Nucleotide Protein
    Heading Accession and Version

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    Research Materials