U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination
    • Showing Current items.

    WNT4 Wnt family member 4 [ Canis lupus familiaris (dog) ]

    Gene ID: 612367, updated on 17-Aug-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    WNT4provided by VGNC
    Official Full Name
    Wnt family member 4provided by VGNC
    Primary source
    VGNC:VGNC:48424
    See related
    Ensembl:ENSCAFG00845000755
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Orthologs
    human mouse all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See WNT4 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 2 NC_051806.1 (77660017..77687063)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 2 NC_006584.4 (73605854..73632899)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 2 NC_049223.1 (76493182..76520234)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 2 NC_049262.1 (74480520..74507565)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 2 NC_049743.1 (75489331..75516389)

    Chromosome 2 - NC_051806.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC111093639 Neighboring gene uncharacterized LOC106558292 Neighboring gene cell division cycle 42 Neighboring gene SCAN domain-containing protein 1-like

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Methylation Patterns of SOX3, SOX9, and WNT4 Genes in Gonads of Dogs with XX (SRY-Negative) Disorder of Sexual Development. Salamon S, et al. Sex Dev, 2017. PMID 28365713
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. The aim of this study was comparative methylation analysis of CpG islands in promoters of candidate genes for XX DSD: SOX9, SOX3, and WNT4.
      Title: Methylation Patterns of SOX3, SOX9, and WNT4 Genes in Gonads of Dogs with XX (SRY-Negative) Disorder of Sexual Development.
    Submit: New GeneRIF Correction

    Pathways from PubChem

    Go to the top of the page

    General gene information

    Go to the top of the page Help

    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables cytokine activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables frizzled binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in canonical Wnt signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cell fate commitment IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in multicellular organism development IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in neuron differentiation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in extracellular space IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    protein Wnt-4

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051806.1 Reference ROS_Cfam_1.0

      Range
      77660017..77687063
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038659982.1 → XP_038515910.1  protein Wnt-4 isoform X1

      UniProtKB/TrEMBL
      A0A8C0L5Q8, A0A8C0LY82, A0A8I3MCD4, A0A8I3RR10, A0A8P0PMS1
      Related
      ENSCAFP00845000956.1, ENSCAFT00845001252.1
      Conserved Domains (1) summary
      cd19336
      Location:43 → 351
      Wnt_Wnt4; Wnt domain found in protein Wnt-4 and similar proteins

    2. XM_038659983.1 → XP_038515911.1  protein Wnt-4 isoform X2

      UniProtKB/TrEMBL
      A0A8I3RR10, A0A8P0PMS1
      Conserved Domains (1) summary
      cd19336
      Location:43 → 318
      Wnt_Wnt4; Wnt domain found in protein Wnt-4 and similar proteins

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049262.1 Alternate UMICH_Zoey_3.1

      Range
      74480520..74507565
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038470809.1 → XP_038326737.1  protein Wnt-4 isoform X1

      Conserved Domains (1) summary
      cd19336
      Location:43 → 351
      Wnt_Wnt4; Wnt domain found in protein Wnt-4 and similar proteins

    2. XM_038470810.1 → XP_038326738.1  protein Wnt-4 isoform X2

      Conserved Domains (1) summary
      cd19336
      Location:43 → 318
      Wnt_Wnt4; Wnt domain found in protein Wnt-4 and similar proteins

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049743.1 Alternate UNSW_CanFamBas_1.0

      Range
      75489331..75516389
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038595904.1 → XP_038451832.1  protein Wnt-4 isoform X1

      Conserved Domains (1) summary
      cd19336
      Location:43 → 351
      Wnt_Wnt4; Wnt domain found in protein Wnt-4 and similar proteins

    2. XM_038595905.1 → XP_038451833.1  protein Wnt-4 isoform X2

      Conserved Domains (1) summary
      cd19336
      Location:43 → 318
      Wnt_Wnt4; Wnt domain found in protein Wnt-4 and similar proteins

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049223.1 Alternate UU_Cfam_GSD_1.0

      Range
      76493182..76520234
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038531672.1 → XP_038387600.1  protein Wnt-4 isoform X1

      UniProtKB/TrEMBL
      A0A8C0L5Q8, A0A8C0LY82, A0A8I3MCD4, A0A8I3RR10, A0A8P0PMS1
      Conserved Domains (1) summary
      cd19336
      Location:43 → 351
      Wnt_Wnt4; Wnt domain found in protein Wnt-4 and similar proteins

    2. XM_038531673.1 → XP_038387601.1  protein Wnt-4 isoform X2

      UniProtKB/TrEMBL
      A0A8I3RR10, A0A8P0PMS1
      Conserved Domains (1) summary
      cd19336
      Location:43 → 318
      Wnt_Wnt4; Wnt domain found in protein Wnt-4 and similar proteins

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006584.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      73605854..73632899
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038463310.1 → XP_038319238.1  protein Wnt-4 isoform X1

      UniProtKB/TrEMBL
      A0A8C0L5Q8, A0A8C0LY82, A0A8I3MCD4, A0A8I3RR10, A0A8P0PMS1
      Conserved Domains (1) summary
      cd19336
      Location:43 → 351
      Wnt_Wnt4; Wnt domain found in protein Wnt-4 and similar proteins

    2. XM_038463311.1 → XP_038319239.1  protein Wnt-4 isoform X2

      UniProtKB/TrEMBL
      A0A8I3RR10, A0A8P0PMS1
      Conserved Domains (1) summary
      cd19336
      Location:43 → 318
      Wnt_Wnt4; Wnt domain found in protein Wnt-4 and similar proteins
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials