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    DAPK2 death associated protein kinase 2 [ Canis lupus familiaris (dog) ]

    Gene ID: 610682, updated on 17-Aug-2024

    Summary

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    Official Symbol
    DAPK2provided by VGNC
    Official Full Name
    death associated protein kinase 2provided by VGNC
    Primary source
    VGNC:VGNC:59108
    See related
    Ensembl:ENSCAFG00845021918
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Orthologs
    human mouse all
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    Genomic context

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    See DAPK2 in Genome Data Viewer
    Location:
    chromosome: 30
    Exon count:
    17
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 30 NC_051834.1 (28614566..28741234, complement)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 30 NC_006612.4 (28360544..28485020, complement)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 30 NC_049251.1 (28852337..28976558, complement)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 30 NC_049290.1 (28551372..28675829, complement)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 30 NC_049771.1 (28613775..28738321, complement)

    Chromosome 30 - NC_051834.1Genomic Context describing neighboring genes Neighboring gene F-box and leucine rich repeat protein 22 Neighboring gene HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 Neighboring gene uncharacterized LOC111093317 Neighboring gene U6 spliceosomal RNA Neighboring gene cytosolic iron-sulfur assembly component 2A Neighboring gene sorting nexin 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein serine/threonine kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in intracellular signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of apoptotic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    death-associated protein kinase 2; LOW QUALITY PROTEIN: death-associated protein kinase 2
    XP_013965079.1
    XP_013965080.1
    XP_013965081.1
    XP_013965082.1
    XP_022268366.1
    XP_022268367.1
    XP_022268368.1
    XP_038298504.1
    XP_038298505.1
    XP_038298506.1
    XP_038298507.1
    XP_038298508.1
    XP_038298509.1
    XP_038298510.1
    XP_038298511.1
    XP_038317346.1
    XP_038372949.1
    XP_038372950.1
    XP_038372951.1
    XP_038372952.1
    XP_038372953.1
    XP_038372954.1
    XP_038372955.1
    XP_038372956.1
    XP_038436576.1
    XP_038500887.1
    XP_038500888.1
    XP_038500889.1
    XP_038500890.1
    XP_038500891.1
    XP_038500892.1
    XP_038500893.1
    XP_038500894.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051834.1 Reference ROS_Cfam_1.0

      Range
      28614566..28741234 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038442582.1 → XP_038298510.1  death-associated protein kinase 2 isoform X5

      UniProtKB/TrEMBL
      A0A8C0K8R6, A0A8C0NVP9
      Related
      ENSCAFP00845030273.1, ENSCAFT00845038662.1
      Conserved Domains (1) summary
      cd14196
      Location:24 → 292
      STKc_DAPK2; Catalytic domain of the Serine/Threonine Kinase, Death-Associated Protein Kinase 2

    2. XM_038442577.1 → XP_038298505.1  death-associated protein kinase 2 isoform X1

      UniProtKB/TrEMBL
      A0A8C0NXS6
      Conserved Domains (1) summary
      cd14196
      Location:24 → 292
      STKc_DAPK2; Catalytic domain of the Serine/Threonine Kinase, Death-Associated Protein Kinase 2

    3. XM_038442580.1 → XP_038298508.1  death-associated protein kinase 2 isoform X3

      UniProtKB/TrEMBL
      A0A8C0NXS6, A0A8I3PIC8, A0A8P0NN73
      Conserved Domains (1) summary
      cd14196
      Location:17 → 285
      STKc_DAPK2; Catalytic domain of the Serine/Threonine Kinase, Death-Associated Protein Kinase 2

    4. XM_038442576.1 → XP_038298504.1  death-associated protein kinase 2 isoform X1

      UniProtKB/TrEMBL
      A0A8C0NXS6
      Conserved Domains (1) summary
      cd14196
      Location:24 → 292
      STKc_DAPK2; Catalytic domain of the Serine/Threonine Kinase, Death-Associated Protein Kinase 2

    5. XM_038442579.1 → XP_038298507.1  death-associated protein kinase 2 isoform X3

      UniProtKB/TrEMBL
      A0A8C0NXS6, A0A8I3PIC8, A0A8P0NN73
      Related
      ENSCAFP00845030371.1, ENSCAFT00845038785.1
      Conserved Domains (1) summary
      cd14196
      Location:17 → 285
      STKc_DAPK2; Catalytic domain of the Serine/Threonine Kinase, Death-Associated Protein Kinase 2

    6. XM_038442581.1 → XP_038298509.1  death-associated protein kinase 2 isoform X4

      UniProtKB/TrEMBL
      A0A8C0NXS6, A0A8C0TRH3
      Conserved Domains (1) summary
      cl21453
      Location:9 → 262
      PKc_like; Protein Kinases, catalytic domain

    7. XM_038442583.1 → XP_038298511.1  death-associated protein kinase 2 isoform X6

      Conserved Domains (1) summary
      cl21453
      Location:1 → 130
      PKc_like; Protein Kinases, catalytic domain

    8. XM_038442578.1 → XP_038298506.1  death-associated protein kinase 2 isoform X2

      UniProtKB/TrEMBL
      A0A8C0NXS6
      Conserved Domains (1) summary
      cd14196
      Location:20 → 288
      STKc_DAPK2; Catalytic domain of the Serine/Threonine Kinase, Death-Associated Protein Kinase 2

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049290.1 Alternate UMICH_Zoey_3.1

      Range
      28551372..28675829 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038517027.1 → XP_038372955.1  death-associated protein kinase 2 isoform X5

      Conserved Domains (1) summary
      cd14196
      Location:24 → 292
      STKc_DAPK2; Catalytic domain of the Serine/Threonine Kinase, Death-Associated Protein Kinase 2

    2. XM_038517022.1 → XP_038372950.1  death-associated protein kinase 2 isoform X1

      Conserved Domains (1) summary
      cd14196
      Location:24 → 292
      STKc_DAPK2; Catalytic domain of the Serine/Threonine Kinase, Death-Associated Protein Kinase 2

    3. XM_038517025.1 → XP_038372953.1  death-associated protein kinase 2 isoform X3

      Conserved Domains (1) summary
      cd14196
      Location:17 → 285
      STKc_DAPK2; Catalytic domain of the Serine/Threonine Kinase, Death-Associated Protein Kinase 2

    4. XM_038517021.1 → XP_038372949.1  death-associated protein kinase 2 isoform X1

      Conserved Domains (1) summary
      cd14196
      Location:24 → 292
      STKc_DAPK2; Catalytic domain of the Serine/Threonine Kinase, Death-Associated Protein Kinase 2

    5. XM_038517024.1 → XP_038372952.1  death-associated protein kinase 2 isoform X3

      Conserved Domains (1) summary
      cd14196
      Location:17 → 285
      STKc_DAPK2; Catalytic domain of the Serine/Threonine Kinase, Death-Associated Protein Kinase 2

    6. XM_038517026.1 → XP_038372954.1  death-associated protein kinase 2 isoform X4

      Conserved Domains (1) summary
      cl21453
      Location:9 → 262
      PKc_like; Protein Kinases, catalytic domain

    7. XM_038517028.1 → XP_038372956.1  death-associated protein kinase 2 isoform X6

      Conserved Domains (1) summary
      cl21453
      Location:1 → 130
      PKc_like; Protein Kinases, catalytic domain

    8. XM_038517023.1 → XP_038372951.1  death-associated protein kinase 2 isoform X2

      Conserved Domains (1) summary
      cd14196
      Location:20 → 288
      STKc_DAPK2; Catalytic domain of the Serine/Threonine Kinase, Death-Associated Protein Kinase 2

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049771.1 Alternate UNSW_CanFamBas_1.0

      Range
      28613775..28738321 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038644965.1 → XP_038500893.1  death-associated protein kinase 2 isoform X5

      Conserved Domains (1) summary
      cd14196
      Location:24 → 292
      STKc_DAPK2; Catalytic domain of the Serine/Threonine Kinase, Death-Associated Protein Kinase 2

    2. XM_038644960.1 → XP_038500888.1  death-associated protein kinase 2 isoform X1

      Conserved Domains (1) summary
      cd14196
      Location:24 → 292
      STKc_DAPK2; Catalytic domain of the Serine/Threonine Kinase, Death-Associated Protein Kinase 2

    3. XM_038644963.1 → XP_038500891.1  death-associated protein kinase 2 isoform X3

      Conserved Domains (1) summary
      cd14196
      Location:17 → 285
      STKc_DAPK2; Catalytic domain of the Serine/Threonine Kinase, Death-Associated Protein Kinase 2

    4. XM_038644959.1 → XP_038500887.1  death-associated protein kinase 2 isoform X1

      Conserved Domains (1) summary
      cd14196
      Location:24 → 292
      STKc_DAPK2; Catalytic domain of the Serine/Threonine Kinase, Death-Associated Protein Kinase 2

    5. XM_038644962.1 → XP_038500890.1  death-associated protein kinase 2 isoform X3

      Conserved Domains (1) summary
      cd14196
      Location:17 → 285
      STKc_DAPK2; Catalytic domain of the Serine/Threonine Kinase, Death-Associated Protein Kinase 2

    6. XM_038644964.1 → XP_038500892.1  death-associated protein kinase 2 isoform X4

      Conserved Domains (1) summary
      cl21453
      Location:9 → 262
      PKc_like; Protein Kinases, catalytic domain

    7. XM_038644966.1 → XP_038500894.1  death-associated protein kinase 2 isoform X6

      Conserved Domains (1) summary
      cl21453
      Location:1 → 130
      PKc_like; Protein Kinases, catalytic domain

    8. XM_038644961.1 → XP_038500889.1  death-associated protein kinase 2 isoform X2

      Conserved Domains (1) summary
      cd14196
      Location:20 → 288
      STKc_DAPK2; Catalytic domain of the Serine/Threonine Kinase, Death-Associated Protein Kinase 2

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049251.1 Alternate UU_Cfam_GSD_1.0

      Range
      28852337..28976558 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038580648.1 → XP_038436576.1  LOW QUALITY PROTEIN: death-associated protein kinase 2 isoform X5

      UniProtKB/TrEMBL
      A0A8C0K8R6, A0A8C0NVP9
      Conserved Domains (1) summary
      cd14196
      Location:24 → 292
      STKc_DAPK2; Catalytic domain of the Serine/Threonine Kinase, Death-Associated Protein Kinase 2

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006612.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      28360544..28485020 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_022412660.2 → XP_022268368.1  death-associated protein kinase 2 isoform X5

      UniProtKB/TrEMBL
      A0A8C0K8R6, A0A8C0NVP9
      Conserved Domains (1) summary
      cd14196
      Location:24 → 292
      STKc_DAPK2; Catalytic domain of the Serine/Threonine Kinase, Death-Associated Protein Kinase 2

    2. XM_038461418.1 → XP_038317346.1  death-associated protein kinase 2 isoform X1

      UniProtKB/TrEMBL
      A0A8C0NXS6
      Conserved Domains (1) summary
      cd14196
      Location:24 → 292
      STKc_DAPK2; Catalytic domain of the Serine/Threonine Kinase, Death-Associated Protein Kinase 2

    3. XM_014109605.3 → XP_013965080.1  death-associated protein kinase 2 isoform X3

      UniProtKB/TrEMBL
      A0A8C0NXS6, A0A8I3PIC8, A0A8P0NN73
      Conserved Domains (1) summary
      cd14196
      Location:17 → 285
      STKc_DAPK2; Catalytic domain of the Serine/Threonine Kinase, Death-Associated Protein Kinase 2

    4. XM_022412658.2 → XP_022268366.1  death-associated protein kinase 2 isoform X1

      UniProtKB/TrEMBL
      A0A8C0NXS6
      Conserved Domains (1) summary
      cd14196
      Location:24 → 292
      STKc_DAPK2; Catalytic domain of the Serine/Threonine Kinase, Death-Associated Protein Kinase 2

    5. XM_014109604.2 → XP_013965079.1  death-associated protein kinase 2 isoform X3

      UniProtKB/TrEMBL
      A0A8C0NXS6, A0A8I3PIC8, A0A8P0NN73
      Conserved Domains (1) summary
      cd14196
      Location:17 → 285
      STKc_DAPK2; Catalytic domain of the Serine/Threonine Kinase, Death-Associated Protein Kinase 2

    6. XM_014109606.3 → XP_013965081.1  death-associated protein kinase 2 isoform X4

      UniProtKB/TrEMBL
      A0A8C0NXS6, A0A8C0TRH3
      Conserved Domains (1) summary
      cl21453
      Location:9 → 262
      PKc_like; Protein Kinases, catalytic domain

    7. XM_014109607.3 → XP_013965082.1  death-associated protein kinase 2 isoform X6

      Conserved Domains (1) summary
      cl21453
      Location:1 → 130
      PKc_like; Protein Kinases, catalytic domain

    8. XM_022412659.2 → XP_022268367.1  death-associated protein kinase 2 isoform X2

      UniProtKB/TrEMBL
      A0A8C0NXS6
      Conserved Domains (1) summary
      cd14196
      Location:20 → 288
      STKc_DAPK2; Catalytic domain of the Serine/Threonine Kinase, Death-Associated Protein Kinase 2
    Nucleotide Protein
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