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    DKK1 dickkopf WNT signaling pathway inhibitor 1 [ Canis lupus familiaris (dog) ]

    Gene ID: 609600, updated on 17-Aug-2024

    Summary

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    Official Symbol
    DKK1provided by VGNC
    Official Full Name
    dickkopf WNT signaling pathway inhibitor 1provided by VGNC
    Primary source
    VGNC:VGNC:52929
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Orthologs
    human mouse all
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    Genomic context

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    See DKK1 in Genome Data Viewer
    Location:
    chromosome: 26
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 26 NC_051830.1 (37227528..37231046, complement)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 26 NC_006608.4 (35582535..35586059, complement)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 26 NC_049247.1 (35960801..35964325, complement)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 26 NC_049286.1 (35133162..35136678, complement)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 26 NC_049767.1 (34718578..34722096, complement)

    Chromosome 26 - NC_051830.1Genomic Context describing neighboring genes Neighboring gene 60S ribosomal protein L17-like Neighboring gene uncharacterized LOC102154823 Neighboring gene uncharacterized LOC102154924 Neighboring gene protein kinase cGMP-dependent 1 Neighboring gene uncharacterized LOC111092581

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables co-receptor binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables receptor antagonist activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in multicellular organism development IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in negative regulation of canonical Wnt signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in extracellular space IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    dickkopf-related protein 1
    Names
    dickkopf 1 homolog
    dickkopf homolog 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051830.1 Reference ROS_Cfam_1.0

      Range
      37227528..37231046 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038436152.1 → XP_038292080.1  dickkopf-related protein 1

      UniProtKB/TrEMBL
      A0A8C0R8F5
      Conserved Domains (1) summary
      pfam04706
      Location:85 → 142
      Dickkopf_N; Dickkopf N-terminal cysteine-rich region

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049286.1 Alternate UMICH_Zoey_3.1

      Range
      35133162..35136678 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038512627.1 → XP_038368555.1  dickkopf-related protein 1

      Conserved Domains (1) summary
      pfam04706
      Location:85 → 142
      Dickkopf_N; Dickkopf N-terminal cysteine-rich region

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049767.1 Alternate UNSW_CanFamBas_1.0

      Range
      34718578..34722096 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038638754.1 → XP_038494682.1  dickkopf-related protein 1

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049247.1 Alternate UU_Cfam_GSD_1.0

      Range
      35960801..35964325 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038574537.1 → XP_038430465.1  dickkopf-related protein 1

      UniProtKB/TrEMBL
      A0A8C0R8F5
      Conserved Domains (1) summary
      pfam04706
      Location:85 → 142
      Dickkopf_N; Dickkopf N-terminal cysteine-rich region

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006608.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      35582535..35586059 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038459226.1 → XP_038315154.1  dickkopf-related protein 1

      UniProtKB/TrEMBL
      A0A8C0R8F5
      Conserved Domains (1) summary
      pfam04706
      Location:85 → 142
      Dickkopf_N; Dickkopf N-terminal cysteine-rich region
    Nucleotide Protein
    Heading Accession and Version

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