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    NPFFR1 neuropeptide FF receptor 1 [ Canis lupus familiaris (dog) ]

    Gene ID: 609566, updated on 5-Mar-2024

    Summary

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    Gene symbol
    NPFFR1
    Gene description
    neuropeptide FF receptor 1
    See related
    Ensembl:ENSCAFG00845004215
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Orthologs
    human mouse all
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    Genomic context

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    See NPFFR1 in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 4 NC_051808.1 (21466975..21492765, complement)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 4 NC_006586.4 (21323904..21351213, complement)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 4 NC_049225.1 (21920758..21946551, complement)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 4 NC_049264.1 (21364430..21390200, complement)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 4 NC_049745.1 (21569576..21595343, complement)

    Chromosome 4 - NC_051808.1Genomic Context describing neighboring genes Neighboring gene secretion associated Ras related GTPase 1A Neighboring gene inorganic pyrophosphatase 1 Neighboring gene leucine rich repeat containing 20 Neighboring gene uncharacterized LOC111095471

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables neuropeptide receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables peptide binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in G protein-coupled receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    LOW QUALITY PROTEIN: neuropeptide FF receptor 1; neuropeptide FF receptor 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051808.1 Reference ROS_Cfam_1.0

      Range
      21466975..21492765 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038662819.1 → XP_038518747.1  LOW QUALITY PROTEIN: neuropeptide FF receptor 1 isoform X1

      UniProtKB/TrEMBL
      A0A8C0NC84, A0A8P0SIU0
      Related
      ENSCAFP00845005971.1, ENSCAFT00845007560.1
      Conserved Domains (2) summary
      cd14964
      Location:45 → 71
      7tm_GPCRs; TM helix 1 [structural motif]
      cl28897
      Location:44 → 348
      7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049264.1 Alternate UMICH_Zoey_3.1

      Range
      21364430..21390200 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038473153.1 → XP_038329081.1  LOW QUALITY PROTEIN: neuropeptide FF receptor 1 isoform X1

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049745.1 Alternate UNSW_CanFamBas_1.0

      Range
      21569576..21595343 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038598517.1 → XP_038454445.1  neuropeptide FF receptor 1 isoform X1

      Conserved Domains (2) summary
      cd14964
      Location:45 → 71
      7tm_GPCRs; TM helix 1 [structural motif]
      cl28897
      Location:44 → 348
      7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

    2. XM_038598524.1 → XP_038454452.1  neuropeptide FF receptor 1 isoform X3

      Conserved Domains (2) summary
      cd14964
      Location:45 → 71
      7tm_GPCRs; TM helix 1 [structural motif]
      cl28897
      Location:44 → 140
      7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

    3. XM_038598523.1 → XP_038454451.1  neuropeptide FF receptor 1 isoform X2

    4. XM_038598522.1 → XP_038454450.1  neuropeptide FF receptor 1 isoform X1

      Conserved Domains (2) summary
      cd14964
      Location:45 → 71
      7tm_GPCRs; TM helix 1 [structural motif]
      cl28897
      Location:44 → 348
      7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

    5. XM_038598518.1 → XP_038454446.1  neuropeptide FF receptor 1 isoform X1

      Conserved Domains (2) summary
      cd14964
      Location:45 → 71
      7tm_GPCRs; TM helix 1 [structural motif]
      cl28897
      Location:44 → 348
      7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

    6. XM_038598520.1 → XP_038454448.1  neuropeptide FF receptor 1 isoform X1

      Conserved Domains (2) summary
      cd14964
      Location:45 → 71
      7tm_GPCRs; TM helix 1 [structural motif]
      cl28897
      Location:44 → 348
      7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

    7. XM_038598516.1 → XP_038454444.1  neuropeptide FF receptor 1 isoform X1

      Conserved Domains (2) summary
      cd14964
      Location:45 → 71
      7tm_GPCRs; TM helix 1 [structural motif]
      cl28897
      Location:44 → 348
      7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

    8. XM_038598519.1 → XP_038454447.1  neuropeptide FF receptor 1 isoform X1

      Conserved Domains (2) summary
      cd14964
      Location:45 → 71
      7tm_GPCRs; TM helix 1 [structural motif]
      cl28897
      Location:44 → 348
      7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049225.1 Alternate UU_Cfam_GSD_1.0

      Range
      21920758..21946551 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038534203.1 → XP_038390131.1  neuropeptide FF receptor 1 isoform X1

      UniProtKB/TrEMBL
      A0A8C0NC84, A0A8P0SIU0
      Conserved Domains (2) summary
      cd14964
      Location:45 → 71
      7tm_GPCRs; TM helix 1 [structural motif]
      cl28897
      Location:44 → 348
      7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

    2. XM_038534210.1 → XP_038390138.1  neuropeptide FF receptor 1 isoform X5

      Conserved Domains (2) summary
      cd14964
      Location:45 → 71
      7tm_GPCRs; TM helix 1 [structural motif]
      cl28897
      Location:44 → 140
      7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

    3. XM_038534209.1 → XP_038390137.1  neuropeptide FF receptor 1 isoform X4

    4. XM_038534207.1 → XP_038390135.1  neuropeptide FF receptor 1 isoform X1

      UniProtKB/TrEMBL
      A0A8C0NC84, A0A8P0SIU0
      Conserved Domains (2) summary
      cd14964
      Location:45 → 71
      7tm_GPCRs; TM helix 1 [structural motif]
      cl28897
      Location:44 → 348
      7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

    5. XM_038534204.1 → XP_038390132.1  neuropeptide FF receptor 1 isoform X1

      UniProtKB/TrEMBL
      A0A8C0NC84, A0A8P0SIU0
      Conserved Domains (2) summary
      cd14964
      Location:45 → 71
      7tm_GPCRs; TM helix 1 [structural motif]
      cl28897
      Location:44 → 348
      7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

    6. XM_038534206.1 → XP_038390134.1  neuropeptide FF receptor 1 isoform X1

      UniProtKB/TrEMBL
      A0A8C0NC84, A0A8P0SIU0
      Conserved Domains (2) summary
      cd14964
      Location:45 → 71
      7tm_GPCRs; TM helix 1 [structural motif]
      cl28897
      Location:44 → 348
      7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

    7. XM_038534202.1 → XP_038390130.1  neuropeptide FF receptor 1 isoform X1

      UniProtKB/TrEMBL
      A0A8C0NC84, A0A8P0SIU0
      Conserved Domains (2) summary
      cd14964
      Location:45 → 71
      7tm_GPCRs; TM helix 1 [structural motif]
      cl28897
      Location:44 → 348
      7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

    8. XM_038534205.1 → XP_038390133.1  neuropeptide FF receptor 1 isoform X1

      UniProtKB/TrEMBL
      A0A8C0NC84, A0A8P0SIU0
      Conserved Domains (2) summary
      cd14964
      Location:45 → 71
      7tm_GPCRs; TM helix 1 [structural motif]
      cl28897
      Location:44 → 348
      7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006586.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      21323904..21351213 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038486534.1 → XP_038342462.1  neuropeptide FF receptor 1 isoform X6

      UniProtKB/TrEMBL
      A0A8P0SIU0
      Conserved Domains (2) summary
      cd14964
      Location:91 → 117
      7tm_GPCRs; TM helix 1 [structural motif]
      cl28897
      Location:90 → 394
      7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily
    Nucleotide Protein
    Heading Accession and Version

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