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    LEMD3 LEM domain containing 3 [ Canis lupus familiaris (dog) ]

    Gene ID: 608380, updated on 17-Aug-2024

    Summary

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    Official Symbol
    LEMD3provided by VGNC
    Official Full Name
    LEM domain containing 3provided by VGNC
    Primary source
    VGNC:VGNC:42633
    See related
    Ensembl:ENSCAFG00845012211
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Orthologs
    human mouse all
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    Genomic context

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    See LEMD3 in Genome Data Viewer
    Location:
    chromosome: 10
    Exon count:
    16
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 10 NC_051814.1 (7887012..7959867)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 10 NC_006592.4 (7711419..7784249)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 10 NC_049231.1 (8135524..8208304)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 10 NC_049270.1 (7763790..7836639)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 10 NC_049751.1 (8003513..8063233)

    Chromosome 10 - NC_051814.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC119873584 Neighboring gene WNT inhibitory factor 1 Neighboring gene uncharacterized LOC102157003 Neighboring gene methionine sulfoxide reductase B3 Neighboring gene U6 spliceosomal RNA Neighboring gene uncharacterized LOC111097584

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables chromatin DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in negative regulation of BMP signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in nuclear envelope organization IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nuclear inner membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    LOW QUALITY PROTEIN: inner nuclear membrane protein Man1; inner nuclear membrane protein Man1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051814.1 Reference ROS_Cfam_1.0

      Range
      7887012..7959867
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038679256.1 → XP_038535184.1  inner nuclear membrane protein Man1 isoform X1

      UniProtKB/TrEMBL
      A0A8C0TBY2, A0A8I3RWY7
      Related
      ENSCAFP00845017079.1, ENSCAFT00845021719.1
      Conserved Domains (3) summary
      pfam09402
      Location:559 → 771
      MSC; Man1-Src1p-C-terminal domain
      cd12286
      Location:808 → 899
      RRM_Man1; RNA recognition motif (RRM) found in inner nuclear membrane protein Man1 (Man1) and similar proteins
      cl02649
      Location:12 → 50
      LEM; LEM (Lap2/Emerin/Man1) domain found in emerin, lamina-associated polypeptide 2 (LAP2), inner nuclear membrane protein Man1 and similar proteins

    RNA

    1. XR_005433128.1 RNA Sequence

    2. XR_005433127.1 RNA Sequence

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049270.1 Alternate UMICH_Zoey_3.1

      Range
      7763790..7836639
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038488033.1 → XP_038343961.1  inner nuclear membrane protein Man1 isoform X1

    RNA

    1. XR_005331641.1 RNA Sequence

    2. XR_005331640.1 RNA Sequence

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049751.1 Alternate UNSW_CanFamBas_1.0

      Range
      8003513..8063233
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038613447.1 → XP_038469375.1  LOW QUALITY PROTEIN: inner nuclear membrane protein Man1 isoform X2

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049231.1 Alternate UU_Cfam_GSD_1.0

      Range
      8135524..8208304
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038549927.1 → XP_038405855.1  inner nuclear membrane protein Man1 isoform X1

      UniProtKB/TrEMBL
      A0A8C0TBY2

    RNA

    1. XR_005365346.1 RNA Sequence

    2. XR_005365345.1 RNA Sequence

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006592.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      7711419..7784249
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_022424879.2 → XP_022280587.2  inner nuclear membrane protein Man1 isoform X1

      UniProtKB/TrEMBL
      A0A8C0TBY2
      Conserved Domains (3) summary
      pfam09402
      Location:555 → 767
      MSC; Man1-Src1p-C-terminal domain
      cd12286
      Location:804 → 895
      RRM_Man1; RNA recognition motif (RRM) found in inner nuclear membrane protein Man1 (Man1) and similar proteins
      cl02649
      Location:13 → 51
      LEM; LEM (Lap2/Emerin/Man1) domain found in emerin, lamina-associated polypeptide 2 (LAP2), inner nuclear membrane protein Man1 and similar proteins

    RNA

    1. XR_005410786.1 RNA Sequence

    2. XR_005410784.1 RNA Sequence

    Nucleotide Protein
    Heading Accession and Version

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