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    HIBCH 3-hydroxyisobutyryl-CoA hydrolase [ Canis lupus familiaris (dog) ]

    Gene ID: 607040, updated on 17-Aug-2024

    Summary

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    Official Symbol
    HIBCHprovided by VGNC
    Official Full Name
    3-hydroxyisobutyryl-CoA hydrolaseprovided by VGNC
    Primary source
    VGNC:VGNC:57386
    See related
    Ensembl:ENSCAFG00845024697
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Orthologs
    human mouse all
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    Genomic context

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    See HIBCH in Genome Data Viewer
    Location:
    chromosome: 37
    Exon count:
    16
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 37 NC_051841.1 (735664..832314, complement)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 37 NC_006619.4 (1797343..1893653, complement)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 37 NC_049258.1 (742338..838606, complement)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 37 NC_049297.1 (746020..842670, complement)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 37 NC_049778.1 (713636..809463, complement)

    Chromosome 37 - NC_051841.1Genomic Context describing neighboring genes Neighboring gene chromosome 37 C2orf88 homolog Neighboring gene myostatin Neighboring gene uncharacterized LOC106558329 Neighboring gene inositol polyphosphate-1-phosphatase Neighboring gene uncharacterized LOC111090013 Neighboring gene uncharacterized LOC111094338

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables 3-hydroxyisobutyryl-CoA hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in valine catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    3-hydroxyisobutyryl-CoA hydrolase, mitochondrial
    Names
    3-hydroxyisobutyryl-Coenzyme A hydrolase
    XP_005640511.1
    XP_022270675.1
    XP_022270676.1
    XP_038303302.1
    XP_038303303.1
    XP_038303304.1
    XP_038377366.1
    XP_038377367.1
    XP_038377368.1
    XP_038441070.1
    XP_038441071.1
    XP_038441072.1
    XP_038505480.1
    XP_038505481.1
    XP_038505482.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051841.1 Reference ROS_Cfam_1.0

      Range
      735664..832314 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038447374.1 → XP_038303302.1  3-hydroxyisobutyryl-CoA hydrolase, mitochondrial isoform X1

      UniProtKB/TrEMBL
      A0A8C0QWD5, A0A8C0RLB1, A0A8C0SJE6, A0A8I3PSJ0, A0A8I3S4X3
      Related
      ENSCAFP00845034334.1, ENSCAFT00845043814.1
      Conserved Domains (1) summary
      pfam16113
      Location:43 → 371
      ECH_2; Enoyl-CoA hydratase/isomerase

    2. XM_038447376.1 → XP_038303304.1  3-hydroxyisobutyryl-CoA hydrolase, mitochondrial isoform X2

      UniProtKB/TrEMBL
      A0A8C0K2S8, A0A8C0SJE6, A0A8I3PSJ0
      Conserved Domains (1) summary
      pfam16113
      Location:20 → 348
      ECH_2; Enoyl-CoA hydratase/isomerase

    3. XM_038447375.1 → XP_038303303.1  3-hydroxyisobutyryl-CoA hydrolase, mitochondrial isoform X2

      UniProtKB/TrEMBL
      A0A8C0K2S8, A0A8C0SJE6, A0A8I3PSJ0
      Conserved Domains (1) summary
      pfam16113
      Location:20 → 348
      ECH_2; Enoyl-CoA hydratase/isomerase

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049297.1 Alternate UMICH_Zoey_3.1

      Range
      746020..842670 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038521438.1 → XP_038377366.1  3-hydroxyisobutyryl-CoA hydrolase, mitochondrial isoform X1

      Conserved Domains (1) summary
      pfam16113
      Location:43 → 371
      ECH_2; Enoyl-CoA hydratase/isomerase

    2. XM_038521440.1 → XP_038377368.1  3-hydroxyisobutyryl-CoA hydrolase, mitochondrial isoform X2

      Conserved Domains (1) summary
      pfam16113
      Location:20 → 348
      ECH_2; Enoyl-CoA hydratase/isomerase

    3. XM_038521439.1 → XP_038377367.1  3-hydroxyisobutyryl-CoA hydrolase, mitochondrial isoform X2

      Conserved Domains (1) summary
      pfam16113
      Location:20 → 348
      ECH_2; Enoyl-CoA hydratase/isomerase

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049778.1 Alternate UNSW_CanFamBas_1.0

      Range
      713636..809463 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038649552.1 → XP_038505480.1  3-hydroxyisobutyryl-CoA hydrolase, mitochondrial isoform X1

      Conserved Domains (1) summary
      pfam16113
      Location:43 → 371
      ECH_2; Enoyl-CoA hydratase/isomerase

    2. XM_038649554.1 → XP_038505482.1  3-hydroxyisobutyryl-CoA hydrolase, mitochondrial isoform X2

      Conserved Domains (1) summary
      pfam16113
      Location:20 → 348
      ECH_2; Enoyl-CoA hydratase/isomerase

    3. XM_038649553.1 → XP_038505481.1  3-hydroxyisobutyryl-CoA hydrolase, mitochondrial isoform X2

      Conserved Domains (1) summary
      pfam16113
      Location:20 → 348
      ECH_2; Enoyl-CoA hydratase/isomerase

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049258.1 Alternate UU_Cfam_GSD_1.0

      Range
      742338..838606 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038585142.1 → XP_038441070.1  3-hydroxyisobutyryl-CoA hydrolase, mitochondrial isoform X1

      UniProtKB/TrEMBL
      A0A8C0QWD5, A0A8C0RLB1, A0A8C0SJE6, A0A8I3PSJ0, A0A8I3S4X3
      Conserved Domains (1) summary
      pfam16113
      Location:43 → 371
      ECH_2; Enoyl-CoA hydratase/isomerase

    2. XM_038585144.1 → XP_038441072.1  3-hydroxyisobutyryl-CoA hydrolase, mitochondrial isoform X2

      UniProtKB/TrEMBL
      A0A8C0K2S8, A0A8C0SJE6, A0A8I3PSJ0
      Conserved Domains (1) summary
      pfam16113
      Location:20 → 348
      ECH_2; Enoyl-CoA hydratase/isomerase

    3. XM_038585143.1 → XP_038441071.1  3-hydroxyisobutyryl-CoA hydrolase, mitochondrial isoform X2

      UniProtKB/TrEMBL
      A0A8C0K2S8, A0A8C0SJE6, A0A8I3PSJ0
      Conserved Domains (1) summary
      pfam16113
      Location:20 → 348
      ECH_2; Enoyl-CoA hydratase/isomerase

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006619.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      1797343..1893653 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005640454.3 → XP_005640511.1  3-hydroxyisobutyryl-CoA hydrolase, mitochondrial isoform X1

      UniProtKB/TrEMBL
      A0A8C0QWD5, A0A8C0RLB1, A0A8C0SJE6, A0A8I3PSJ0, A0A8I3S4X3
      Conserved Domains (1) summary
      pfam16113
      Location:43 → 371
      ECH_2; Enoyl-CoA hydratase/isomerase

    2. XM_022414968.2 → XP_022270676.1  3-hydroxyisobutyryl-CoA hydrolase, mitochondrial isoform X2

      UniProtKB/TrEMBL
      A0A8C0K2S8, A0A8C0SJE6, A0A8I3PSJ0
      Conserved Domains (1) summary
      pfam16113
      Location:20 → 348
      ECH_2; Enoyl-CoA hydratase/isomerase

    3. XM_022414967.2 → XP_022270675.1  3-hydroxyisobutyryl-CoA hydrolase, mitochondrial isoform X2

      UniProtKB/TrEMBL
      A0A8C0K2S8, A0A8C0SJE6, A0A8I3PSJ0
      Conserved Domains (1) summary
      pfam16113
      Location:20 → 348
      ECH_2; Enoyl-CoA hydratase/isomerase
    Nucleotide Protein
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