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    Cadm1 cell adhesion molecule 1 [ Mus musculus (house mouse) ]

    Gene ID: 54725, updated on 2-Nov-2024

    Summary

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    Official Symbol
    Cadm1provided by MGI
    Official Full Name
    cell adhesion molecule 1provided by MGI
    Primary source
    MGI:MGI:1889272
    See related
    Ensembl:ENSMUSG00000032076 AllianceGenome:MGI:1889272
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Bl2; ST17; Igsf4; Necl2; RA175; Tslc1; Igsf4a; RA175A; RA175B; RA175C; RA175N; SgIGSF; SynCam; 2900073G06Rik; 3100001I08Rik
    Summary
    Enables PDZ domain binding activity; protein homodimerization activity; and signaling receptor binding activity. Involved in several processes, including heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules; homophilic cell adhesion via plasma membrane adhesion molecules; and synapse organization. Acts upstream of or within bone development; calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules; and unidimensional cell growth. Located in several cellular components, including basolateral plasma membrane; dendrite; and synaptic vesicle. Is active in Schaffer collateral - CA1 synapse; glutamatergic synapse; and synaptic membrane. Is expressed in several structures, including central nervous system; metanephros; peripheral nervous system; sensory organ; and tooth. Human ortholog(s) of this gene implicated in breast carcinoma and prostate cancer. Orthologous to human CADM1 (cell adhesion molecule 1). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Broad expression in CNS E18 (RPKM 13.0), CNS E14 (RPKM 8.1) and 15 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Cadm1 in Genome Data Viewer
    Location:
    9 A5.3; 9 25.83 cM
    Exon count:
    19
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 9 NC_000075.7 (47441468..47773578)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 9 NC_000075.6 (47530170..47862280)

    Chromosome 9 - NC_000075.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_24045 Neighboring gene predicted gene, 57541 Neighboring gene STARR-seq mESC enhancer starr_24046 Neighboring gene predicted gene, 22286 Neighboring gene STARR-seq mESC enhancer starr_24053 Neighboring gene STARR-seq mESC enhancer starr_24054 Neighboring gene predicted gene 10677 Neighboring gene STARR-seq mESC enhancer starr_24056 Neighboring gene predicted gene, 32016 Neighboring gene STARR-seq mESC enhancer starr_24057 Neighboring gene STARR-seq mESC enhancer starr_24058 Neighboring gene predicted gene, 40518

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Excitatory Synaptic Drive and Feedforward Inhibition in the Hippocampal CA3 Circuit Are Regulated by SynCAM 1. Park KA, et al. J Neurosci, 2016 Jul 13. PMID 27413156, Free PMC Article
    2. Epigenetic silencing of cell adhesion molecule 1 in different cancer progenitor cells of transgenic c-Myc and c-Raf mouse lung tumors. Reamon-Buettner SM, et al. Cancer Res, 2008 Sep 15. PMID 18794147
    3. Role of the spermatogenic-Sertoli cell interaction through cell adhesion molecule-1 (CADM1) in spermatogenesis. Wakayama T, et al. Anat Sci Int, 2009 Sep. PMID 19337787
    4. Progression of Pulmonary Emphysema and Continued Increase in Ectodomain Shedding of Cell Adhesion Molecule 1 After Cessation of Cigarette Smoke Exposure in Mice. Ri A, et al. Front Cell Dev Biol, 2018. PMID 29892598, Free PMC Article
    5. Cadm1 expression and function in the mouse lens. De Maria A, et al. Invest Ophthalmol Vis Sci, 2011 Apr. PMID 21217103, Free PMC Article

    See all (147) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. NECL2 regulates blood-testis barrier dynamics in mouse testes.
      Title: NECL2 regulates blood-testis barrier dynamics in mouse testes.
    2. Concerted roles of LRRTM1 and SynCAM 1 in organizing prefrontal cortex synapses and cognitive functions.
      Title: Concerted roles of LRRTM1 and SynCAM 1 in organizing prefrontal cortex synapses and cognitive functions.
    3. Epstein Barr virus-mediated transformation of B cells from XIAP-deficient patients leads to increased expression of the tumor suppressor CADM1.
      Title: Epstein Barr virus-mediated transformation of B cells from XIAP-deficient patients leads to increased expression of the tumor suppressor CADM1.
    4. Trans-homophilic interaction of CADM1 promotes organ infiltration of T-cell lymphoma by adhesion to vascular endothelium.
      Title: Trans-homophilic interaction of CADM1 promotes organ infiltration of T-cell lymphoma by adhesion to vascular endothelium.
    5. Evidence of islet CADM1-mediated immune cell interactions during human type 1 diabetes.
      Title: Evidence of islet CADM1-mediated immune cell interactions during human type 1 diabetes.
    6. The CADM1 tumor suppressor gene is a major candidate gene in MDS with deletion of the long arm of chromosome 11.
      Title: The CADM1 tumor suppressor gene is a major candidate gene in MDS with deletion of the long arm of chromosome 11.
    7. Expression of cell adhesion molecule 1 in human and murine endometrial glandular cells and its increase during the proliferative phase by estrogen and cell density.
      Title: Expression of cell adhesion molecule 1 in human and murine endometrial glandular cells and its increase during the proliferative phase by estrogen and cell density.
    8. Potentiating the Antitumor Activity of Cytotoxic T Cells via the Transmembrane Domain of IGSF4 That Increases TCR Avidity.
      Title: Potentiating the Antitumor Activity of Cytotoxic T Cells via the Transmembrane Domain of IGSF4 That Increases TCR Avidity.
    9. Differential Contribution of Cadm1-Cadm3 Cell Adhesion Molecules to Peripheral Myelinated Axons.
      Title: Differential Contribution of Cadm1-Cadm3 Cell Adhesion Molecules to Peripheral Myelinated Axons.
    10. CADM1 suppresses c-Src activation by binding with Cbp on membrane lipid rafts and intervenes colon carcinogenesis.
      Title: CADM1 suppresses c-Src activation by binding with Cbp on membrane lipid rafts and intervenes colon carcinogenesis.
    Submit: New GeneRIF Correction See all GeneRIFs (75)

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables PDZ domain binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables cell adhesion molecule binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables protein homodimerization activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables signaling receptor binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables signaling receptor binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables signaling receptor binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    Process Evidence Code Pubs
    involved_in apoptotic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within bone development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within cell adhesion IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in cell differentiation IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in cell recognition IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in cell recognition IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in cell recognition ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in detection of stimulus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in detection of stimulus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in detection of stimulus ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in homophilic cell adhesion via plasma membrane adhesion molecules IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in homophilic cell adhesion via plasma membrane adhesion molecules IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in liver development ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in lymphocyte migration into lymphoid organs IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in maintenance of postsynaptic specialization structure IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in maintenance of postsynaptic specialization structure IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in negative regulation of ERBB4 signaling pathway ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in negative regulation of protein phosphorylation ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in positive regulation of cytokine production ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in positive regulation of natural killer cell mediated cytotoxicity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in positive regulation of natural killer cell mediated cytotoxicity ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in presynapse assembly IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in presynapse assembly IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in retrograde trans-synaptic signaling by trans-synaptic protein complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in retrograde trans-synaptic signaling by trans-synaptic protein complex IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in spermatogenesis IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in susceptibility to natural killer cell mediated cytotoxicity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in susceptibility to natural killer cell mediated cytotoxicity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in susceptibility to natural killer cell mediated cytotoxicity ISO
    Inferred from Sequence Orthology
    more info
    		  
    acts_upstream_of_or_within synapse assembly IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in synapse assembly IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in synapse assembly IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in synaptic membrane adhesion IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in synaptic membrane adhesion IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    acts_upstream_of_or_within unidimensional cell growth IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in Schaffer collateral - CA1 synapse IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in Schaffer collateral - CA1 synapse IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    located_in axon IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in basolateral plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in cell-cell junction IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in dendrite IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in dendrite ISO
    Inferred from Sequence Orthology
    more info
    		  
    is_active_in glutamatergic synapse IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in glutamatergic synapse IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    is_active_in neuron projection IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in plasma membrane ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in postsynaptic density ISO
    Inferred from Sequence Orthology
    more info
    		  
    is_active_in postsynaptic membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in presynaptic membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in synapse IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in synapse IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in synaptic vesicle IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    cell adhesion molecule 1
    Names
    NECL-2
    TSLC-1
    immunoglobulin superfamily member 4
    immunoglobulin superfamily member 4A
    immunosuperfamily protein Bl2
    nectin-like 2
    nectin-like protein 2
    spermatogenic immunoglobulin superfamily
    synaptic cell adhesion molecule
    tumor suppressor in lung cancer 1

    NCBI Reference Sequences (RefSeq)

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    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001025600.1 → NP_001020771.1  cell adhesion molecule 1 isoform d precursor

      See identical proteins and their annotated locations for NP_001020771.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (4) lacks two in-frame exons compared to variant 1. The resulting isoform (d) has the same N- and C-termini but is shorter compared to isoform a.
      Source sequence(s)
      AK053839, AY351388, CAAA01092855
      Consensus CDS
      CCDS23147.1
      UniProtKB/TrEMBL
      Q1WIL9
      Related
      ENSMUSP00000034581.4, ENSMUST00000034581.4
      Conserved Domains (4) summary
      smart00294
      Location:370 → 388
      4.1m; putative band 4.1 homologues' binding motif
      cd05881
      Location:49 → 143
      Ig1_Necl-2; First (N-terminal) immunoglobulin (Ig)-like domain of nectin-like molecule 2
      cd05883
      Location:164 → 245
      Ig2_Necl-2; Second immunoglobulin (Ig)-like domain of nectin-like molecule 2 (also known as cell adhesion molecule 1 (CADM1))
      smart00410
      Location:255 → 333
      IG_like; Immunoglobulin like

    2. NM_001310841.1 → NP_001297770.1  cell adhesion molecule 1 isoform e precursor

      See identical proteins and their annotated locations for NP_001297770.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (5) contains an alternate in-frame exon in the 3' coding region compared to variant 1. It encodes isoform e, which is longer than isoform a.
      Source sequence(s)
      AC121870, AC183268, AI848016, AK013911, BB343438, BC094661, JQ782219
      Consensus CDS
      CCDS80990.1
      UniProtKB/TrEMBL
      E9PYN1, Q1WIL9
      Related
      ENSMUSP00000124119.2, ENSMUST00000152459.8
      Conserved Domains (5) summary
      smart00294
      Location:427 → 445
      4.1m; putative band 4.1 homologues' binding motif
      smart00410
      Location:255 → 333
      IG_like; Immunoglobulin like
      cd00096
      Location:266 → 270
      Ig; Ig strand B [structural motif]
      cd05881
      Location:50 → 143
      IgV_1_Necl-2; First (N-terminal) immunoglobulin (Ig)-like domain of nectin-like molecule 2; member of the V-set of Ig superfamily (IgSF) domains
      cd05883
      Location:144 → 242
      IgI_2_Necl-2; Second immunoglobulin (Ig)-like domain of nectin-like molecule 2 (Necl-2); member of the I-set of Ig superfamily domains

    3. NM_018770.3 → NP_061240.3  cell adhesion molecule 1 isoform c precursor

      See identical proteins and their annotated locations for NP_061240.3

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) lacks an in-frame exon compared to variant 1. The resulting isoform (c) has the same N- and C-termini but is shorter compared to isoform a.
      Source sequence(s)
      AK053839, BQ043739, CAAA01092855
      Consensus CDS
      CCDS23148.1
      UniProtKB/TrEMBL
      Q1WIL9
      Related
      ENSMUSP00000110194.2, ENSMUST00000114547.8
      Conserved Domains (4) summary
      smart00294
      Location:398 → 416
      4.1m; putative band 4.1 homologues' binding motif
      cd05881
      Location:49 → 143
      Ig1_Necl-2; First (N-terminal) immunoglobulin (Ig)-like domain of nectin-like molecule 2
      cd05883
      Location:164 → 245
      Ig2_Necl-2; Second immunoglobulin (Ig)-like domain of nectin-like molecule 2 (also known as cell adhesion molecule 1 (CADM1))
      smart00410
      Location:255 → 333
      IG_like; Immunoglobulin like

    4. NM_207675.2 → NP_997558.2  cell adhesion molecule 1 isoform a precursor

      See identical proteins and their annotated locations for NP_997558.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) encodes isoform a.
      Source sequence(s)
      AK013911, AK053839, CAAA01092855
      Consensus CDS
      CCDS23149.1
      UniProtKB/Swiss-Prot
      Q6F3J3, Q7TNL1, Q80VG4, Q8K3T6, Q8R4L1, Q8R5M8, Q9QYL5, Q9QYL6, Q9Z2H8
      UniProtKB/TrEMBL
      Q1WIL9
      Related
      ENSMUSP00000083073.3, ENSMUST00000085909.9
      Conserved Domains (4) summary
      smart00294
      Location:409 → 427
      4.1m; putative band 4.1 homologues' binding motif
      cd05881
      Location:49 → 143
      Ig1_Necl-2; First (N-terminal) immunoglobulin (Ig)-like domain of nectin-like molecule 2
      cd05883
      Location:164 → 245
      Ig2_Necl-2; Second immunoglobulin (Ig)-like domain of nectin-like molecule 2 (also known as cell adhesion molecule 1 (CADM1))
      smart00410
      Location:255 → 333
      IG_like; Immunoglobulin like

    5. NM_207676.2 → NP_997559.1  cell adhesion molecule 1 isoform b precursor

      See identical proteins and their annotated locations for NP_997559.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) lacks an in-frame exon compared to variant 1. The resulting isoform (b) has the same N- and C-termini but is shorter compared to isoform a.
      Source sequence(s)
      AK053839, BC057125, CAAA01092855
      Consensus CDS
      CCDS23150.1
      UniProtKB/TrEMBL
      Q1WIL9
      Related
      ENSMUSP00000110195.2, ENSMUST00000114548.8
      Conserved Domains (4) summary
      smart00294
      Location:381 → 399
      4.1m; putative band 4.1 homologues' binding motif
      cd05881
      Location:49 → 143
      Ig1_Necl-2; First (N-terminal) immunoglobulin (Ig)-like domain of nectin-like molecule 2
      cd05883
      Location:164 → 245
      Ig2_Necl-2; Second immunoglobulin (Ig)-like domain of nectin-like molecule 2 (also known as cell adhesion molecule 1 (CADM1))
      smart00410
      Location:255 → 333
      IG_like; Immunoglobulin like

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000075.7 Reference GRCm39 C57BL/6J

      Range
      47441468..47773578
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006510497.5 → XP_006510560.1  cell adhesion molecule 1 isoform X1

      See identical proteins and their annotated locations for XP_006510560.1

      UniProtKB/TrEMBL
      Q1WIL9
      Conserved Domains (4) summary
      smart00294
      Location:399 → 417
      4.1m; putative band 4.1 homologues' binding motif
      cd05881
      Location:49 → 143
      Ig1_Necl-2; First (N-terminal) immunoglobulin (Ig)-like domain of nectin-like molecule 2
      cd05883
      Location:164 → 245
      Ig2_Necl-2; Second immunoglobulin (Ig)-like domain of nectin-like molecule 2 (also known as cell adhesion molecule 1 (CADM1))
      smart00410
      Location:255 → 333
      IG_like; Immunoglobulin like

    2. XM_036155131.1 → XP_036011024.1  cell adhesion molecule 1 isoform X4

      UniProtKB/TrEMBL
      Q9QYL3
      Conserved Domains (4) summary
      smart00294
      Location:249 → 267
      4.1m; putative band 4.1 homologues' binding motif
      smart00409
      Location:105 → 183
      IG; Immunoglobulin
      cd00096
      Location:1 → 4
      Ig; Ig strand A' [structural motif]
      cl11960
      Location:1 → 92
      Ig; Immunoglobulin domain

    3. XM_017313487.3 → XP_017168976.1  cell adhesion molecule 1 isoform X2

      UniProtKB/TrEMBL
      Q9QYL4
      Conserved Domains (4) summary
      smart00294
      Location:277 → 295
      4.1m; putative band 4.1 homologues' binding motif
      smart00409
      Location:105 → 183
      IG; Immunoglobulin
      cd00096
      Location:1 → 4
      Ig; Ig strand A' [structural motif]
      cl11960
      Location:1 → 92
      Ig; Immunoglobulin domain

    4. XM_036155137.1 → XP_036011030.1  cell adhesion molecule 1 isoform X6

      UniProtKB/TrEMBL
      Q9QYL3
      Conserved Domains (4) summary
      smart00294
      Location:231 → 249
      4.1m; putative band 4.1 homologues' binding motif
      smart00409
      Location:105 → 183
      IG; Immunoglobulin
      cd00096
      Location:1 → 4
      Ig; Ig strand A' [structural motif]
      cl11960
      Location:1 → 92
      Ig; Immunoglobulin domain

    5. XM_036155128.1 → XP_036011021.1  cell adhesion molecule 1 isoform X3

      UniProtKB/TrEMBL
      Q9QYL4
      Conserved Domains (3) summary
      smart00409
      Location:105 → 183
      IG; Immunoglobulin
      cd00096
      Location:1 → 4
      Ig; Ig strand A' [structural motif]
      cl11960
      Location:1 → 92
      Ig; Immunoglobulin domain

    6. XM_036155133.1 → XP_036011026.1  cell adhesion molecule 1 isoform X5

      UniProtKB/TrEMBL
      Q9QYL4
      Conserved Domains (3) summary
      smart00409
      Location:105 → 183
      IG; Immunoglobulin
      cd00096
      Location:1 → 4
      Ig; Ig strand A' [structural motif]
      cl11960
      Location:1 → 92
      Ig; Immunoglobulin domain

    7. XM_036155124.1 → XP_036011017.1  cell adhesion molecule 1 isoform X2

      UniProtKB/TrEMBL
      Q9QYL4
      Conserved Domains (4) summary
      smart00294
      Location:277 → 295
      4.1m; putative band 4.1 homologues' binding motif
      smart00409
      Location:105 → 183
      IG; Immunoglobulin
      cd00096
      Location:1 → 4
      Ig; Ig strand A' [structural motif]
      cl11960
      Location:1 → 92
      Ig; Immunoglobulin domain

    8. XM_036155129.1 → XP_036011022.1  cell adhesion molecule 1 isoform X3

      UniProtKB/TrEMBL
      Q9QYL4
      Conserved Domains (3) summary
      smart00409
      Location:105 → 183
      IG; Immunoglobulin
      cd00096
      Location:1 → 4
      Ig; Ig strand A' [structural motif]
      cl11960
      Location:1 → 92
      Ig; Immunoglobulin domain

    9. XM_036155125.1 → XP_036011018.1  cell adhesion molecule 1 isoform X2

      UniProtKB/TrEMBL
      Q9QYL4
      Conserved Domains (4) summary
      smart00294
      Location:277 → 295
      4.1m; putative band 4.1 homologues' binding motif
      smart00409
      Location:105 → 183
      IG; Immunoglobulin
      cd00096
      Location:1 → 4
      Ig; Ig strand A' [structural motif]
      cl11960
      Location:1 → 92
      Ig; Immunoglobulin domain

    10. XM_036155130.1 → XP_036011023.1  cell adhesion molecule 1 isoform X3

      UniProtKB/TrEMBL
      Q9QYL4
      Conserved Domains (3) summary
      smart00409
      Location:105 → 183
      IG; Immunoglobulin
      cd00096
      Location:1 → 4
      Ig; Ig strand A' [structural motif]
      cl11960
      Location:1 → 92
      Ig; Immunoglobulin domain

    11. XM_036155134.1 → XP_036011027.1  cell adhesion molecule 1 isoform X5

      UniProtKB/TrEMBL
      Q9QYL4
      Conserved Domains (3) summary
      smart00409
      Location:105 → 183
      IG; Immunoglobulin
      cd00096
      Location:1 → 4
      Ig; Ig strand A' [structural motif]
      cl11960
      Location:1 → 92
      Ig; Immunoglobulin domain

    12. XM_036155138.1 → XP_036011031.1  cell adhesion molecule 1 isoform X6

      UniProtKB/TrEMBL
      Q9QYL3
      Conserved Domains (4) summary
      smart00294
      Location:231 → 249
      4.1m; putative band 4.1 homologues' binding motif
      smart00409
      Location:105 → 183
      IG; Immunoglobulin
      cd00096
      Location:1 → 4
      Ig; Ig strand A' [structural motif]
      cl11960
      Location:1 → 92
      Ig; Immunoglobulin domain

    13. XM_030244460.2 → XP_030100320.1  cell adhesion molecule 1 isoform X6

      UniProtKB/TrEMBL
      Q9QYL3
      Conserved Domains (4) summary
      smart00294
      Location:231 → 249
      4.1m; putative band 4.1 homologues' binding motif
      smart00409
      Location:105 → 183
      IG; Immunoglobulin
      cd00096
      Location:1 → 4
      Ig; Ig strand A' [structural motif]
      cl11960
      Location:1 → 92
      Ig; Immunoglobulin domain

    14. XM_017313488.2 → XP_017168977.1  cell adhesion molecule 1 isoform X2

      UniProtKB/TrEMBL
      Q9QYL4
      Conserved Domains (4) summary
      smart00294
      Location:277 → 295
      4.1m; putative band 4.1 homologues' binding motif
      smart00409
      Location:105 → 183
      IG; Immunoglobulin
      cd00096
      Location:1 → 4
      Ig; Ig strand A' [structural motif]
      cl11960
      Location:1 → 92
      Ig; Immunoglobulin domain

    15. XM_036155132.1 → XP_036011025.1  cell adhesion molecule 1 isoform X4

      UniProtKB/TrEMBL
      Q9QYL3
      Conserved Domains (4) summary
      smart00294
      Location:249 → 267
      4.1m; putative band 4.1 homologues' binding motif
      smart00409
      Location:105 → 183
      IG; Immunoglobulin
      cd00096
      Location:1 → 4
      Ig; Ig strand A' [structural motif]
      cl11960
      Location:1 → 92
      Ig; Immunoglobulin domain

    16. XM_036155127.1 → XP_036011020.1  cell adhesion molecule 1 isoform X2

      UniProtKB/TrEMBL
      Q9QYL4
      Conserved Domains (4) summary
      smart00294
      Location:277 → 295
      4.1m; putative band 4.1 homologues' binding motif
      smart00409
      Location:105 → 183
      IG; Immunoglobulin
      cd00096
      Location:1 → 4
      Ig; Ig strand A' [structural motif]
      cl11960
      Location:1 → 92
      Ig; Immunoglobulin domain

    17. XM_036155136.1 → XP_036011029.1  cell adhesion molecule 1 isoform X5

      UniProtKB/TrEMBL
      Q9QYL4
      Conserved Domains (3) summary
      smart00409
      Location:105 → 183
      IG; Immunoglobulin
      cd00096
      Location:1 → 4
      Ig; Ig strand A' [structural motif]
      cl11960
      Location:1 → 92
      Ig; Immunoglobulin domain

    18. XM_036155135.1 → XP_036011028.1  cell adhesion molecule 1 isoform X5

      UniProtKB/TrEMBL
      Q9QYL4
      Conserved Domains (3) summary
      smart00409
      Location:105 → 183
      IG; Immunoglobulin
      cd00096
      Location:1 → 4
      Ig; Ig strand A' [structural motif]
      cl11960
      Location:1 → 92
      Ig; Immunoglobulin domain

    19. XM_036155126.1 → XP_036011019.1  cell adhesion molecule 1 isoform X2

      UniProtKB/TrEMBL
      Q9QYL4
      Conserved Domains (4) summary
      smart00294
      Location:277 → 295
      4.1m; putative band 4.1 homologues' binding motif
      smart00409
      Location:105 → 183
      IG; Immunoglobulin
      cd00096
      Location:1 → 4
      Ig; Ig strand A' [structural motif]
      cl11960
      Location:1 → 92
      Ig; Immunoglobulin domain
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8R5M8.2 GenPept UniProtKB/Swiss-Prot:Q8R5M8

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