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    CAPN11 calpain 11 [ Bos taurus (domestic cattle) ]

    Gene ID: 527966, updated on 4-Oct-2024

    Summary

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    Official Symbol
    CAPN11provided by VGNC
    Official Full Name
    calpain 11provided by VGNC
    Primary source
    VGNC:VGNC:26742
    See related
    BGD:BT26310; Ensembl:ENSBTAG00000021066
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See CAPN11 in Genome Data Viewer
    Location:
    chromosome: 23
    Exon count:
    21
    Annotation release Status Assembly Chr Location
    RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 23 NC_037350.1 (17687157..17705325)

    Chromosome 23 - NC_037350.1Genomic Context describing neighboring genes Neighboring gene mitochondrial ribosomal protein L14 Neighboring gene transfer RNA alanine (anticodon UGC) Neighboring gene transmembrane protein 63B Neighboring gene cysteine-rich protein 1-like Neighboring gene myomixer, myoblast fusion factor Neighboring gene solute carrier family 29 member 1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037350.1 Chromosome 23 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables calcium ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables calcium-dependent cysteine-type endopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in proteolysis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    calpain-11
    XP_015315311.2
    XP_059736565.1
    XP_059736566.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037350.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      17687157..17705325
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_059880583.1 → XP_059736566.1  calpain-11 isoform X2

    2. XM_015459825.3 → XP_015315311.2  calpain-11 isoform X3

      UniProtKB/TrEMBL
      F1MXQ5
      Related
      ENSBTAP00000004690.7, ENSBTAT00000004690.7
      Conserved Domains (4) summary
      pfam00648
      Location:61 → 357
      Peptidase_C2; Calpain family cysteine protease
      pfam01067
      Location:378 → 522
      Calpain_III; Calpain large subunit, domain III
      cd15897
      Location:549 → 578
      EFh_PEF; EF-hand motif [structural motif]
      cl25352
      Location:549 → 718
      EFh_PEF; The penta-EF hand (PEF) family

    3. XM_059880582.1 → XP_059736565.1  calpain-11 isoform X1

    Nucleotide Protein Strain
    Heading Accession and Version

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