U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination
    • Showing Current items.

    CUL4B cullin 4B [ Canis lupus familiaris (dog) ]

    Gene ID: 492102, updated on 17-Aug-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    CUL4Bprovided by VGNC
    Official Full Name
    cullin 4Bprovided by VGNC
    Primary source
    VGNC:VGNC:39732
    See related
    Ensembl:ENSCAFG00845022607
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Orthologs
    human mouse all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See CUL4B in Genome Data Viewer
    Location:
    chromosome: X
    Exon count:
    26
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) X NC_051843.1 (94236531..94284539, complement)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) X NC_006621.4 (78521518..78569760, complement)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) X NC_049260.1 (93223172..93271175, complement)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) X NC_049299.1 (91685541..91733782, complement)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) X NC_049780.1 (93448317..93496329, complement)

    Chromosome X - NC_051843.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC119868232 Neighboring gene eukaryotic translation initiation factor 4E type 2-like Neighboring gene U6 spliceosomal RNA Neighboring gene 40S ribosomal protein S2-like Neighboring gene uncharacterized LOC111094921 Neighboring gene MCTS1 re-initiation and release factor

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    GeneRIFs: Gene References Into Functions

    General gene information

    Go to the top of the page Help

    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ubiquitin protein ligase binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in DNA damage response IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein ubiquitination IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in ubiquitin-dependent protein catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of Cul4B-RING E3 ubiquitin ligase complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    cullin-4B

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051843.1 Reference ROS_Cfam_1.0

      Range
      94236531..94284539 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038450780.1 → XP_038306708.1  cullin-4B isoform X3

      UniProtKB/TrEMBL
      A0A8I3PD29
      Conserved Domains (2) summary
      smart00884
      Location:913 → 978
      Cullin_Nedd8; Cullin protein neddylation domain
      pfam00888
      Location:286 → 885
      Cullin; Cullin family

    2. XM_038450782.1 → XP_038306710.1  cullin-4B isoform X5

      UniProtKB/TrEMBL
      A0A8I3PV51
      Conserved Domains (2) summary
      smart00884
      Location:842 → 907
      Cullin_Nedd8; Cullin protein neddylation domain
      pfam00888
      Location:215 → 814
      Cullin; Cullin family

    3. XM_038450777.1 → XP_038306705.1  cullin-4B isoform X1

      UniProtKB/TrEMBL
      A0A8I3PD29
      Conserved Domains (2) summary
      smart00884
      Location:950 → 1015
      Cullin_Nedd8; Cullin protein neddylation domain
      pfam00888
      Location:323 → 922
      Cullin; Cullin family

    4. XM_038450781.1 → XP_038306709.1  cullin-4B isoform X4

      UniProtKB/TrEMBL
      A0A8I3PV51
      Related
      ENSCAFP00845032189.1, ENSCAFT00845041077.1
      Conserved Domains (2) summary
      smart00884
      Location:879 → 944
      Cullin_Nedd8; Cullin protein neddylation domain
      pfam00888
      Location:252 → 851
      Cullin; Cullin family

    5. XM_038450778.1 → XP_038306706.1  cullin-4B isoform X2

      UniProtKB/TrEMBL
      A0A8I3PD29, A0A8I3PE50
      Related
      ENSCAFP00845032038.1, ENSCAFT00845040909.1
      Conserved Domains (2) summary
      smart00884
      Location:948 → 1013
      Cullin_Nedd8; Cullin protein neddylation domain
      pfam00888
      Location:323 → 920
      Cullin; Cullin family

    6. XM_038450784.1 → XP_038306712.1  cullin-4B isoform X7

      UniProtKB/TrEMBL
      A0A8I3PI16, A0A8I3PSQ6
      Related
      ENSCAFP00845032281.1, ENSCAFT00845041189.1
      Conserved Domains (2) summary
      smart00884
      Location:829 → 894
      Cullin_Nedd8; Cullin protein neddylation domain
      pfam00888
      Location:204 → 801
      Cullin; Cullin family

    7. XM_038450783.1 → XP_038306711.1  cullin-4B isoform X6

      UniProtKB/TrEMBL
      A0A8I3PSQ6
      Conserved Domains (2) summary
      smart00884
      Location:831 → 896
      Cullin_Nedd8; Cullin protein neddylation domain
      pfam00888
      Location:204 → 803
      Cullin; Cullin family

    8. XM_038450785.1 → XP_038306713.1  cullin-4B isoform X8

      UniProtKB/TrEMBL
      A0A8C0JRJ4, A0A8I3PSQ6, A0A8I3S3A7, A0A8P0PQ22, A0A8P0TU95
      Related
      ENSCAFP00845031490.1, ENSCAFT00845040205.1
      Conserved Domains (2) summary
      smart00884
      Location:646 → 711
      Cullin_Nedd8; Cullin protein neddylation domain
      pfam00888
      Location:21 → 618
      Cullin; Cullin family

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049299.1 Alternate UMICH_Zoey_3.1

      Range
      91685541..91733782 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038524247.1 → XP_038380175.1  cullin-4B isoform X3

    2. XM_038524249.1 → XP_038380177.1  cullin-4B isoform X5

    3. XM_038524245.1 → XP_038380173.1  cullin-4B isoform X1

      Conserved Domains (2) summary
      smart00884
      Location:950 → 1015
      Cullin_Nedd8; Cullin protein neddylation domain
      pfam00888
      Location:323 → 922
      Cullin; Cullin family

    4. XM_038524248.1 → XP_038380176.1  cullin-4B isoform X4

      Conserved Domains (2) summary
      smart00884
      Location:879 → 944
      Cullin_Nedd8; Cullin protein neddylation domain
      pfam00888
      Location:252 → 851
      Cullin; Cullin family

    5. XM_038524246.1 → XP_038380174.1  cullin-4B isoform X2

      Conserved Domains (2) summary
      smart00884
      Location:948 → 1013
      Cullin_Nedd8; Cullin protein neddylation domain
      pfam00888
      Location:323 → 920
      Cullin; Cullin family

    6. XM_038524251.1 → XP_038380179.1  cullin-4B isoform X7

      Conserved Domains (2) summary
      smart00884
      Location:829 → 894
      Cullin_Nedd8; Cullin protein neddylation domain
      pfam00888
      Location:204 → 801
      Cullin; Cullin family

    7. XM_038524250.1 → XP_038380178.1  cullin-4B isoform X6

      Conserved Domains (2) summary
      smart00884
      Location:831 → 896
      Cullin_Nedd8; Cullin protein neddylation domain
      pfam00888
      Location:204 → 803
      Cullin; Cullin family

    8. XM_038524252.1 → XP_038380180.1  cullin-4B isoform X8

      Conserved Domains (2) summary
      smart00884
      Location:646 → 711
      Cullin_Nedd8; Cullin protein neddylation domain
      pfam00888
      Location:21 → 618
      Cullin; Cullin family

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049780.1 Alternate UNSW_CanFamBas_1.0

      Range
      93448317..93496329 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038652736.1 → XP_038508664.1  cullin-4B isoform X3

    2. XM_038652738.1 → XP_038508666.1  cullin-4B isoform X5

    3. XM_038652734.1 → XP_038508662.1  cullin-4B isoform X1

      Conserved Domains (2) summary
      smart00884
      Location:950 → 1015
      Cullin_Nedd8; Cullin protein neddylation domain
      pfam00888
      Location:323 → 922
      Cullin; Cullin family

    4. XM_038652737.1 → XP_038508665.1  cullin-4B isoform X4

      Conserved Domains (2) summary
      smart00884
      Location:879 → 944
      Cullin_Nedd8; Cullin protein neddylation domain
      pfam00888
      Location:252 → 851
      Cullin; Cullin family

    5. XM_038652735.1 → XP_038508663.1  cullin-4B isoform X2

      Conserved Domains (2) summary
      smart00884
      Location:948 → 1013
      Cullin_Nedd8; Cullin protein neddylation domain
      pfam00888
      Location:323 → 920
      Cullin; Cullin family

    6. XM_038652740.1 → XP_038508668.1  cullin-4B isoform X7

      Conserved Domains (2) summary
      smart00884
      Location:829 → 894
      Cullin_Nedd8; Cullin protein neddylation domain
      pfam00888
      Location:204 → 801
      Cullin; Cullin family

    7. XM_038652739.1 → XP_038508667.1  cullin-4B isoform X6

      Conserved Domains (2) summary
      smart00884
      Location:831 → 896
      Cullin_Nedd8; Cullin protein neddylation domain
      pfam00888
      Location:204 → 803
      Cullin; Cullin family

    8. XM_038652741.1 → XP_038508669.1  cullin-4B isoform X8

      Conserved Domains (2) summary
      smart00884
      Location:646 → 711
      Cullin_Nedd8; Cullin protein neddylation domain
      pfam00888
      Location:21 → 618
      Cullin; Cullin family

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049260.1 Alternate UU_Cfam_GSD_1.0

      Range
      93223172..93271175 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038588217.1 → XP_038444145.1  cullin-4B isoform X3

      UniProtKB/TrEMBL
      A0A8I3PD29

    2. XM_038588219.1 → XP_038444147.1  cullin-4B isoform X5

      UniProtKB/TrEMBL
      A0A8C0P7B0, A0A8P0NUY9

    3. XM_038588215.1 → XP_038444143.1  cullin-4B isoform X1

      UniProtKB/TrEMBL
      A0A8I3PD29
      Conserved Domains (2) summary
      smart00884
      Location:950 → 1015
      Cullin_Nedd8; Cullin protein neddylation domain
      pfam00888
      Location:323 → 922
      Cullin; Cullin family

    4. XM_038588218.1 → XP_038444146.1  cullin-4B isoform X4

      UniProtKB/TrEMBL
      A0A8C0P7B0, A0A8P0NUY9
      Conserved Domains (2) summary
      smart00884
      Location:879 → 944
      Cullin_Nedd8; Cullin protein neddylation domain
      pfam00888
      Location:252 → 851
      Cullin; Cullin family

    5. XM_038588216.1 → XP_038444144.1  cullin-4B isoform X2

      UniProtKB/TrEMBL
      A0A8C0PB39, A0A8I3PD29, A0A8P0P312
      Conserved Domains (2) summary
      smart00884
      Location:948 → 1013
      Cullin_Nedd8; Cullin protein neddylation domain
      pfam00888
      Location:323 → 920
      Cullin; Cullin family

    6. XM_038588221.1 → XP_038444149.1  cullin-4B isoform X7

      UniProtKB/TrEMBL
      A0A8C0JRJ4, A0A8C0JRZ3, A0A8C0P7H0, A0A8P0PE73, A0A8P0TU95
      Conserved Domains (2) summary
      smart00884
      Location:829 → 894
      Cullin_Nedd8; Cullin protein neddylation domain
      pfam00888
      Location:204 → 801
      Cullin; Cullin family

    7. XM_038588220.1 → XP_038444148.1  cullin-4B isoform X6

      UniProtKB/TrEMBL
      A0A8C0JRJ4, A0A8P0TU95
      Conserved Domains (2) summary
      smart00884
      Location:831 → 896
      Cullin_Nedd8; Cullin protein neddylation domain
      pfam00888
      Location:204 → 803
      Cullin; Cullin family

    8. XM_038588222.1 → XP_038444150.1  cullin-4B isoform X8

      UniProtKB/TrEMBL
      A0A8C0JRJ4, A0A8I3PSQ6, A0A8I3S3A7, A0A8P0PQ22, A0A8P0TU95
      Conserved Domains (2) summary
      smart00884
      Location:646 → 711
      Cullin_Nedd8; Cullin protein neddylation domain
      pfam00888
      Location:21 → 618
      Cullin; Cullin family

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006621.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      78521518..78569760 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_014111725.3 → XP_013967200.2  cullin-4B isoform X3

      UniProtKB/TrEMBL
      A0A8I3PD29
      Conserved Domains (2) summary
      smart00884
      Location:913 → 978
      Cullin_Nedd8; Cullin protein neddylation domain
      pfam00888
      Location:287 → 884
      Cullin; Cullin family

    2. XM_022415630.2 → XP_022271338.1  cullin-4B isoform X5

      UniProtKB/TrEMBL
      A0A8C0P7B0, A0A8P0NUY9
      Conserved Domains (2) summary
      smart00884
      Location:842 → 907
      Cullin_Nedd8; Cullin protein neddylation domain
      pfam00888
      Location:216 → 813
      Cullin; Cullin family

    3. XM_038464390.1 → XP_038320318.1  cullin-4B isoform X1

      UniProtKB/TrEMBL
      A0A8I3PD29
      Conserved Domains (2) summary
      smart00884
      Location:950 → 1015
      Cullin_Nedd8; Cullin protein neddylation domain
      pfam00888
      Location:323 → 922
      Cullin; Cullin family

    4. XM_038464391.1 → XP_038320319.1  cullin-4B isoform X4

      UniProtKB/TrEMBL
      A0A8C0P7B0, A0A8P0NUY9
      Conserved Domains (2) summary
      smart00884
      Location:879 → 944
      Cullin_Nedd8; Cullin protein neddylation domain
      pfam00888
      Location:252 → 851
      Cullin; Cullin family

    5. XM_859535.7 → XP_864628.5  cullin-4B isoform X2

      UniProtKB/TrEMBL
      A0A8C0PB39, A0A8I3PD29, A0A8P0P312
      Conserved Domains (2) summary
      smart00884
      Location:948 → 1013
      Cullin_Nedd8; Cullin protein neddylation domain
      pfam00888
      Location:323 → 920
      Cullin; Cullin family

    6. XM_014111727.3 → XP_013967202.1  cullin-4B isoform X7

      UniProtKB/TrEMBL
      A0A8C0JRJ4, A0A8C0JRZ3, A0A8C0P7H0, A0A8P0PE73, A0A8P0TU95
      Conserved Domains (2) summary
      smart00884
      Location:829 → 894
      Cullin_Nedd8; Cullin protein neddylation domain
      pfam00888
      Location:204 → 801
      Cullin; Cullin family

    7. XM_014111726.3 → XP_013967201.1  cullin-4B isoform X6

      UniProtKB/TrEMBL
      A0A8C0JRJ4, A0A8P0TU95
      Conserved Domains (2) summary
      smart00884
      Location:831 → 896
      Cullin_Nedd8; Cullin protein neddylation domain
      pfam00888
      Location:204 → 803
      Cullin; Cullin family

    8. XM_038464392.1 → XP_038320320.1  cullin-4B isoform X8

      UniProtKB/TrEMBL
      A0A8C0JRJ4, A0A8I3PSQ6, A0A8I3S3A7, A0A8P0PQ22, A0A8P0TU95
      Conserved Domains (2) summary
      smart00884
      Location:646 → 711
      Cullin_Nedd8; Cullin protein neddylation domain
      pfam00888
      Location:21 → 618
      Cullin; Cullin family
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials