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    ITGA3 integrin subunit alpha 3 [ Canis lupus familiaris (dog) ]

    Gene ID: 491074, updated on 17-Aug-2024

    Summary

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    Official Symbol
    ITGA3provided by VGNC
    Official Full Name
    integrin subunit alpha 3provided by VGNC
    Primary source
    VGNC:VGNC:42125
    See related
    Ensembl:ENSCAFG00845011823
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Orthologs
    human mouse all
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    Genomic context

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    See ITGA3 in Genome Data Viewer
    Location:
    chromosome: 9
    Exon count:
    26
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 9 NC_051813.1 (26860362..26890161)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 9 NC_006591.4 (25458998..25488798)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 9 NC_049230.1 (26016729..26046536)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 9 NC_049269.1 (25628148..25657945)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 9 NC_049750.1 (25886765..25916569)

    Chromosome 9 - NC_051813.1Genomic Context describing neighboring genes Neighboring gene distal-less homeobox 3 Neighboring gene uncharacterized LOC119873286 Neighboring gene pyruvate dehydrogenase kinase 2 Neighboring gene sterile alpha motif domain containing 14

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables integrin binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cell adhesion mediated by integrin IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cell-cell adhesion IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cell-matrix adhesion IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in integrin-mediated signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in leukocyte migration IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in external side of plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    part_of integrin complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    integrin alpha-3
    Names
    integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051813.1 Reference ROS_Cfam_1.0

      Range
      26860362..26890161
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038675123.1 → XP_038531051.1  integrin alpha-3

      UniProtKB/TrEMBL
      A0A8C0LGI8, A0A8C0S8I9, A0A8I3NFG9
      Related
      ENSCAFP00845016828.1, ENSCAFT00845021412.1
      Conserved Domains (2) summary
      smart00191
      Location:367 → 417
      Int_alpha; Integrin alpha (beta-propellor repeats)
      pfam08441
      Location:462 → 916
      Integrin_alpha2; Integrin alpha

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049269.1 Alternate UMICH_Zoey_3.1

      Range
      25628148..25657945
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038484513.1 → XP_038340441.1  integrin alpha-3

      Conserved Domains (2) summary
      smart00191
      Location:367 → 417
      Int_alpha; Integrin alpha (beta-propellor repeats)
      pfam08441
      Location:462 → 916
      Integrin_alpha2; Integrin alpha

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049750.1 Alternate UNSW_CanFamBas_1.0

      Range
      25886765..25916569
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038610060.1 → XP_038465988.1  integrin alpha-3

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049230.1 Alternate UU_Cfam_GSD_1.0

      Range
      26016729..26046536
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038546032.1 → XP_038401960.1  integrin alpha-3

      UniProtKB/TrEMBL
      A0A8C0LGI8, A0A8C0S8I9, A0A8I3NFG9
      Conserved Domains (2) summary
      smart00191
      Location:367 → 417
      Int_alpha; Integrin alpha (beta-propellor repeats)
      pfam08441
      Location:462 → 916
      Integrin_alpha2; Integrin alpha

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006591.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      25458998..25488798
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005624631.3 → XP_005624688.1  integrin alpha-3

      UniProtKB/TrEMBL
      A0A8C0LGI8, A0A8C0S8I9, A0A8I3NFG9
      Conserved Domains (2) summary
      smart00191
      Location:367 → 417
      Int_alpha; Integrin alpha (beta-propellor repeats)
      pfam08441
      Location:462 → 916
      Integrin_alpha2; Integrin alpha
    Nucleotide Protein
    Heading Accession and Version

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