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    ABCD4 ATP binding cassette subfamily D member 4 [ Canis lupus familiaris (dog) ]

    Gene ID: 490781, updated on 11-Apr-2024

    Summary

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    Official Symbol
    ABCD4provided by VGNC
    Official Full Name
    ATP binding cassette subfamily D member 4provided by VGNC
    Primary source
    VGNC:VGNC:37448
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Orthologs
    human mouse all
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    Genomic context

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    See ABCD4 in Genome Data Viewer
    Location:
    chromosome: 8
    Exon count:
    19
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 8 NC_051812.1 (47715766..47732070, complement)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 8 NC_006590.4 (47173373..47191986, complement)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 8 NC_049229.1 (47793455..47812081, complement)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 8 NC_049268.1 (47384860..47403479, complement)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 8 NC_049749.1 (47406500..47425091, complement)

    Chromosome 8 - NC_051812.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC119873002 Neighboring gene visual system homeobox 2 Neighboring gene vertebrae development associated Neighboring gene synapse differentiation inducing 1 like

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ABC-type transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables ATP hydrolysis activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables long-chain fatty acid transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in fatty acid beta-oxidation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in long-chain fatty acid import into peroxisome IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in peroxisome organization IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in very long-chain fatty acid catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in peroxisomal membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    ATP-binding cassette sub-family D member 4; LOW QUALITY PROTEIN: lysosomal cobalamin transporter ABCD4; lysosomal cobalamin transporter ABCD4

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051812.1 Reference ROS_Cfam_1.0

      Range
      47715766..47732070 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038674184.1 → XP_038530112.1  LOW QUALITY PROTEIN: lysosomal cobalamin transporter ABCD4 isoform X1

      UniProtKB/TrEMBL
      A0A8I3S4Z0
      Conserved Domains (2) summary
      TIGR00954
      Location:16 → 605
      3a01203; Peroxysomal Fatty Acyl CoA Transporter (FAT) Family protein
      pfam06472
      Location:27 → 294
      ABC_membrane_2; ABC transporter transmembrane region 2

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049268.1 Alternate UMICH_Zoey_3.1

      Range
      47384860..47403479 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038483782.1 → XP_038339710.1  lysosomal cobalamin transporter ABCD4 isoform X3

    2. XM_038483781.1 → XP_038339709.1  lysosomal cobalamin transporter ABCD4 isoform X2

    3. XM_038483783.1 → XP_038339711.1  lysosomal cobalamin transporter ABCD4 isoform X4

      Conserved Domains (2) summary
      cd03223
      Location:124 → 335
      ABCD_peroxisomal_ALDP; ATP-binding cassette domain of peroxisomal transporter, subfamily D
      TIGR02868
      Location:19 → 299
      CydC; thiol reductant ABC exporter, CydC subunit

    4. XM_038483784.1 → XP_038339712.1  lysosomal cobalamin transporter ABCD4 isoform X5

    RNA

    1. XR_005329671.1 RNA Sequence

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049749.1 Alternate UNSW_CanFamBas_1.0

      Range
      47406500..47425091 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038609358.1 → XP_038465286.1  lysosomal cobalamin transporter ABCD4 isoform X7

    2. XM_038609357.1 → XP_038465285.1  lysosomal cobalamin transporter ABCD4 isoform X6

    3. XM_038609359.1 → XP_038465287.1  lysosomal cobalamin transporter ABCD4 isoform X8

      Conserved Domains (2) summary
      cd03223
      Location:124 → 335
      ABCD_peroxisomal_ALDP; ATP-binding cassette domain of peroxisomal transporter, subfamily D
      TIGR02868
      Location:19 → 299
      CydC; thiol reductant ABC exporter, CydC subunit

    4. XM_038609360.1 → XP_038465288.1  lysosomal cobalamin transporter ABCD4 isoform X9

    RNA

    1. XR_005397982.1 RNA Sequence

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049229.1 Alternate UU_Cfam_GSD_1.0

      Range
      47793455..47812081 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038545262.1 → XP_038401190.1  lysosomal cobalamin transporter ABCD4 isoform X11

      UniProtKB/TrEMBL
      A0A8I3S4Z0

    2. XM_038545261.1 → XP_038401189.1  lysosomal cobalamin transporter ABCD4 isoform X10

      UniProtKB/TrEMBL
      A0A8C0S8X6, A0A8I3S4Z0, A0A8P0NIE2

    3. XM_038545263.1 → XP_038401191.1  lysosomal cobalamin transporter ABCD4 isoform X12

      Conserved Domains (2) summary
      cd03223
      Location:124 → 335
      ABCD_peroxisomal_ALDP; ATP-binding cassette domain of peroxisomal transporter, subfamily D
      TIGR02868
      Location:19 → 299
      CydC; thiol reductant ABC exporter, CydC subunit

    4. XM_038545264.1 → XP_038401192.1  lysosomal cobalamin transporter ABCD4 isoform X13

    RNA

    1. XR_005363527.1 RNA Sequence

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006590.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      47173373..47191986 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005623658.4 → XP_005623715.1  lysosomal cobalamin transporter ABCD4 isoform X15

      UniProtKB/TrEMBL
      A0A8I3S4Z0
      Conserved Domains (1) summary
      COG4178
      Location:1 → 560
      YddA; ABC-type uncharacterized transport system, permease and ATPase components [General function prediction only]

    2. XM_547903.7 → XP_547903.2  lysosomal cobalamin transporter ABCD4 isoform X14

      UniProtKB/TrEMBL
      A0A8C0S8X6, A0A8I3S4Z0, A0A8P0NIE2
      Conserved Domains (2) summary
      pfam06472
      Location:16 → 294
      ABC_membrane_2; ABC transporter transmembrane region 2
      cl26602
      Location:16 → 600
      SunT; ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain [Defense mechanisms]

    3. XM_022422213.1 → XP_022277921.1  lysosomal cobalamin transporter ABCD4 isoform X16

      Conserved Domains (2) summary
      cd03223
      Location:124 → 335
      ABCD_peroxisomal_ALDP; ATP-binding cassette domain of peroxisomal transporter, subfamily D
      TIGR02868
      Location:19 → 299
      CydC; thiol reductant ABC exporter, CydC subunit

    4. XM_022422214.2 → XP_022277922.1  lysosomal cobalamin transporter ABCD4 isoform X17

      Conserved Domains (1) summary
      cl26602
      Location:31 → 442
      SunT; ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain [Defense mechanisms]

    RNA

    1. XR_292979.4 RNA Sequence

    Nucleotide Protein
    Heading Accession and Version

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