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    RIT2 Ras like without CAAX 2 [ Canis lupus familiaris (dog) ]

    Gene ID: 490475, updated on 17-Aug-2024

    Summary

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    Official Symbol
    RIT2provided by VGNC
    Official Full Name
    Ras like without CAAX 2provided by VGNC
    Primary source
    VGNC:VGNC:45601
    See related
    Ensembl:ENSCAFG00845003778
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Orthologs
    human mouse all
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    Genomic context

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    See RIT2 in Genome Data Viewer
    Location:
    chromosome: 7
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 7 NC_051811.1 (47553975..48020921)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 7 NC_006589.4 (47014511..47480592)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 7 NC_049228.1 (47581850..48049236)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 7 NC_049267.1 (47256327..47722627)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 7 NC_049748.1 (47292605..47760797)

    Chromosome 7 - NC_051811.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC111096900 Neighboring gene synaptotagmin 4 Neighboring gene uncharacterized LOC102153101 Neighboring gene U6 spliceosomal RNA Neighboring gene uncharacterized LOC111096901

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables GDP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables GTP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables GTPase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables calmodulin binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in Ras protein signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of neuron projection development IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    GTP-binding protein Rit2
    XP_005622913.1
    XP_013970921.1
    XP_038337943.1
    XP_038337944.1
    XP_038337945.1
    XP_038337946.1
    XP_038399324.1
    XP_038399325.1
    XP_038399326.1
    XP_038399327.1
    XP_038429406.1
    XP_038463432.1
    XP_038463433.1
    XP_038463434.1
    XP_038463435.1
    XP_038463436.1
    XP_038528121.1
    XP_038528122.1
    XP_038528123.1
    XP_038528124.1
    XP_547597.3

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051811.1 Reference ROS_Cfam_1.0

      Range
      47553975..48020921
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038672194.1 → XP_038528122.1  GTP-binding protein Rit2 isoform X2

      UniProtKB/TrEMBL
      A0A8C0RC24
      Conserved Domains (1) summary
      cl38936
      Location:12 → 167
      P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

    2. XM_038672196.1 → XP_038528124.1  GTP-binding protein Rit2 isoform X3

      UniProtKB/TrEMBL
      A0A8C0RC24
      Conserved Domains (1) summary
      cl38936
      Location:1 → 155
      P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

    3. XM_038672195.1 → XP_038528123.1  GTP-binding protein Rit2 isoform X3

      UniProtKB/TrEMBL
      A0A8C0RC24
      Conserved Domains (1) summary
      cl38936
      Location:1 → 155
      P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

    4. XM_038672193.1 → XP_038528121.1  GTP-binding protein Rit2 isoform X1

      UniProtKB/TrEMBL
      A0A8C0QDI3, A0A8C0QYV5, A0A8C0RC24, A0A8I3MQY9
      Related
      ENSCAFP00845005403.1, ENSCAFT00845006791.1
      Conserved Domains (1) summary
      cd04141
      Location:19 → 190
      Rit_Rin_Ric; Ras-like protein in all tissues (Rit), Ras-like protein in neurons (Rin) and Ras-related protein which interacts with calmodulin (Ric)

    RNA

    1. XR_005430152.1 RNA Sequence

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049267.1 Alternate UMICH_Zoey_3.1

      Range
      47256327..47722627
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038482016.1 → XP_038337944.1  GTP-binding protein Rit2 isoform X2

      Conserved Domains (1) summary
      cl38936
      Location:12 → 167
      P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

    2. XM_038482018.1 → XP_038337946.1  GTP-binding protein Rit2 isoform X3

      Conserved Domains (1) summary
      cl38936
      Location:1 → 155
      P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

    3. XM_038482017.1 → XP_038337945.1  GTP-binding protein Rit2 isoform X3

      Conserved Domains (1) summary
      cl38936
      Location:1 → 155
      P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

    4. XM_038482015.1 → XP_038337943.1  GTP-binding protein Rit2 isoform X1

      Conserved Domains (1) summary
      cd04141
      Location:19 → 190
      Rit_Rin_Ric; Ras-like protein in all tissues (Rit), Ras-like protein in neurons (Rin) and Ras-related protein which interacts with calmodulin (Ric)

    RNA

    1. XR_005328603.1 RNA Sequence

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049748.1 Alternate UNSW_CanFamBas_1.0

      Range
      47292605..47760797
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038607505.1 → XP_038463433.1  GTP-binding protein Rit2 isoform X2

      Conserved Domains (1) summary
      cl38936
      Location:12 → 167
      P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

    2. XM_038607507.1 → XP_038463435.1  GTP-binding protein Rit2 isoform X3

      Conserved Domains (1) summary
      cl38936
      Location:1 → 155
      P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

    3. XM_038607506.1 → XP_038463434.1  GTP-binding protein Rit2 isoform X3

      Conserved Domains (1) summary
      cl38936
      Location:1 → 155
      P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

    4. XM_038607508.1 → XP_038463436.1  GTP-binding protein Rit2 isoform X3

      Conserved Domains (1) summary
      cl38936
      Location:1 → 155
      P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

    5. XM_038607504.1 → XP_038463432.1  GTP-binding protein Rit2 isoform X1

    RNA

    1. XR_005396947.1 RNA Sequence

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049228.1 Alternate UU_Cfam_GSD_1.0

      Range
      47581850..48049236
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038543397.1 → XP_038399325.1  GTP-binding protein Rit2 isoform X2

      UniProtKB/TrEMBL
      A0A8C0RC24
      Conserved Domains (1) summary
      cl38936
      Location:12 → 167
      P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

    2. XM_038543399.1 → XP_038399327.1  GTP-binding protein Rit2 isoform X3

      UniProtKB/TrEMBL
      A0A8C0RC24
      Conserved Domains (1) summary
      cl38936
      Location:1 → 155
      P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

    3. XM_038543398.1 → XP_038399326.1  GTP-binding protein Rit2 isoform X3

      UniProtKB/TrEMBL
      A0A8C0RC24
      Conserved Domains (1) summary
      cl38936
      Location:1 → 155
      P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

    4. XM_038543396.1 → XP_038399324.1  GTP-binding protein Rit2 isoform X1

      UniProtKB/TrEMBL
      A0A8C0QDI3, A0A8C0QYV5, A0A8C0RC24, A0A8I3MQY9
      Conserved Domains (1) summary
      cd04141
      Location:19 → 190
      Rit_Rin_Ric; Ras-like protein in all tissues (Rit), Ras-like protein in neurons (Rin) and Ras-related protein which interacts with calmodulin (Ric)

    RNA

    1. XR_005362443.1 RNA Sequence

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006589.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      47014511..47480592
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038573478.1 → XP_038429406.1  GTP-binding protein Rit2 isoform X2

      UniProtKB/TrEMBL
      A0A8C0RC24
      Conserved Domains (1) summary
      cl38936
      Location:12 → 167
      P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

    2. XM_014115446.3 → XP_013970921.1  GTP-binding protein Rit2 isoform X3

      UniProtKB/TrEMBL
      A0A8C0RC24
      Conserved Domains (1) summary
      cl38936
      Location:1 → 155
      P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

    3. XM_005622856.4 → XP_005622913.1  GTP-binding protein Rit2 isoform X3

      See identical proteins and their annotated locations for XP_005622913.1

      UniProtKB/TrEMBL
      A0A8C0RC24
      Conserved Domains (1) summary
      cl38936
      Location:1 → 155
      P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

    4. XM_547597.7 → XP_547597.3  GTP-binding protein Rit2 isoform X1

      UniProtKB/TrEMBL
      A0A8C0QDI3, A0A8C0QYV5, A0A8C0RC24, A0A8I3MQY9
      Conserved Domains (1) summary
      cd04141
      Location:19 → 190
      Rit_Rin_Ric; Ras-like protein in all tissues (Rit), Ras-like protein in neurons (Rin) and Ras-related protein which interacts with calmodulin (Ric)

    RNA

    1. XR_005378481.1 RNA Sequence

    Nucleotide Protein
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