CHRNB2 cholinergic receptor nicotinic beta 2 subunit [Canis lupus familiaris (dog)] - Gene

Summary

Official Symbol: CHRNB2provided by VGNC
Official Full Name: cholinergic receptor nicotinic beta 2 subunitprovided by VGNC
Primary source: VGNC:VGNC:39243
See related: Ensembl:ENSCAFG00845014294
Gene type: protein coding
RefSeq status: MODEL
Organism: Canis lupus familiaris (sub-species: familiaris)
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 7

Exon count:: 7

Annotation release	Status	Assembly	Chr	Location
106	current	ROS_Cfam_1.0 (GCF_014441545.1)	7	NC_051811.1 (42656510..42668001, complement)
106	current	Dog10K_Boxer_Tasha (GCF_000002285.5)	7	NC_006589.4 (42277266..42288752, complement)
106	current	UU_Cfam_GSD_1.0 (GCF_011100685.1)	7	NC_049228.1 (42773221..42784709, complement)
106	current	UMICH_Zoey_3.1 (GCF_005444595.1)	7	NC_049267.1 (42435765..42447248, complement)
106	current	UNSW_CanFamBas_1.0 (GCF_013276365.1)	7	NC_049748.1 (42489629..42501090, complement)

Chromosome 7 - NC_051811.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables acetylcholine-gated monoatomic cation-selective channel activity	IEA Inferred from Electronic Annotation more info	PubMed
enables transmembrane signaling receptor activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in chemical synaptic transmission	IEA Inferred from Electronic Annotation more info	PubMed
involved_in monoatomic ion transmembrane transport	IEA Inferred from Electronic Annotation more info	PubMed
involved_in nervous system process	IEA Inferred from Electronic Annotation more info	PubMed
involved_in regulation of membrane potential	IEA Inferred from Electronic Annotation more info	PubMed
involved_in signal transduction	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in neuron projection	IEA Inferred from Electronic Annotation more info	PubMed
located_in postsynaptic membrane	IEA Inferred from Electronic Annotation more info	PubMed
located_in synapse	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: neuronal acetylcholine receptor subunit beta-2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

NC_051811.1 Reference ROS_Cfam_1.0

Range

42656510..42668001 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038672047.1 → XP_038527975.1 neuronal acetylcholine receptor subunit beta-2 isoform X1

UniProtKB/TrEMBL

A0A8C0K5B0, A0A8I3NJ59, A0A8P0SL74

Related

ENSCAFP00845020128.1, ENSCAFT00845025559.1

Conserved Domains (2) summary

TIGR00860
Location:29 → 455

LIC; Cation transporter family protein

cd19025
Location:31 → 234

LGIC_ECD_nAChR_B2; extracellular domain of nicotinic acetylcholine receptor subunit beta 2 (CHRNB2)
XM_038672048.1 → XP_038527976.1 neuronal acetylcholine receptor subunit beta-2 isoform X2

UniProtKB/TrEMBL

A0A8C0K5B0

Conserved Domains (3) summary

TIGR00860
Location:2 → 395

LIC; Cation transporter family protein

cd03558
Location:95 → 109

LGIC_ECD; Cys-loop [structural motif]

cl28912
Location:1 → 174

LGIC_ECD; extracellular domain (ECD) of Cys-loop neurotransmitter-gated ion channels (also known as ligand-gated ion channel (LGIC))

Alternate UMICH_Zoey_3.1

Genomic

NC_049267.1 Alternate UMICH_Zoey_3.1

Range

42435765..42447248 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038481837.1 → XP_038337765.1 neuronal acetylcholine receptor subunit beta-2 isoform X1

Conserved Domains (2) summary

TIGR00860
Location:29 → 455

LIC; Cation transporter family protein

cd19025
Location:31 → 234

LGIC_ECD_nAChR_B2; extracellular domain of nicotinic acetylcholine receptor subunit beta 2 (CHRNB2)
XM_038481838.1 → XP_038337766.1 neuronal acetylcholine receptor subunit beta-2 isoform X2

Conserved Domains (3) summary

TIGR00860
Location:2 → 395

LIC; Cation transporter family protein

cd03558
Location:95 → 109

LGIC_ECD; Cys-loop [structural motif]

cl28912
Location:1 → 174

LGIC_ECD; extracellular domain (ECD) of Cys-loop neurotransmitter-gated ion channels (also known as ligand-gated ion channel (LGIC))

Alternate UNSW_CanFamBas_1.0

Genomic

NC_049748.1 Alternate UNSW_CanFamBas_1.0

Range

42489629..42501090 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038607330.1 → XP_038463258.1 neuronal acetylcholine receptor subunit beta-2 isoform X1

Conserved Domains (2) summary

TIGR00860
Location:29 → 455

LIC; Cation transporter family protein

cd19025
Location:31 → 234

LGIC_ECD_nAChR_B2; extracellular domain of nicotinic acetylcholine receptor subunit beta 2 (CHRNB2)
XM_038607331.1 → XP_038463259.1 neuronal acetylcholine receptor subunit beta-2 isoform X2

Conserved Domains (3) summary

TIGR00860
Location:2 → 395

LIC; Cation transporter family protein

cd03558
Location:95 → 109

LGIC_ECD; Cys-loop [structural motif]

cl28912
Location:1 → 174

LGIC_ECD; extracellular domain (ECD) of Cys-loop neurotransmitter-gated ion channels (also known as ligand-gated ion channel (LGIC))

Alternate UU_Cfam_GSD_1.0

Genomic

NC_049228.1 Alternate UU_Cfam_GSD_1.0

Range

42773221..42784709 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038543221.1 → XP_038399149.1 neuronal acetylcholine receptor subunit beta-2 isoform X1

UniProtKB/TrEMBL

A0A8C0K5B0, A0A8I3NJ59, A0A8P0SL74

Conserved Domains (2) summary

TIGR00860
Location:29 → 455

LIC; Cation transporter family protein

cd19025
Location:31 → 234

LGIC_ECD_nAChR_B2; extracellular domain of nicotinic acetylcholine receptor subunit beta 2 (CHRNB2)
XM_038543222.1 → XP_038399150.1 neuronal acetylcholine receptor subunit beta-2 isoform X2

UniProtKB/TrEMBL

A0A8C0K5B0

Conserved Domains (3) summary

TIGR00860
Location:2 → 395

LIC; Cation transporter family protein

cd03558
Location:95 → 109

LGIC_ECD; Cys-loop [structural motif]

cl28912
Location:1 → 174

LGIC_ECD; extracellular domain (ECD) of Cys-loop neurotransmitter-gated ion channels (also known as ligand-gated ion channel (LGIC))

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

NC_006589.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

Range

42277266..42288752 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_547565.6 → XP_547565.2 neuronal acetylcholine receptor subunit beta-2 isoform X1

UniProtKB/TrEMBL

A0A8C0K5B0, A0A8I3NJ59, A0A8P0SL74

Conserved Domains (2) summary

TIGR00860
Location:29 → 455

LIC; Cation transporter family protein

cd19025
Location:31 → 234

LGIC_ECD_nAChR_B2; extracellular domain of nicotinic acetylcholine receptor subunit beta 2 (CHRNB2)
XM_022421343.2 → XP_022277051.1 neuronal acetylcholine receptor subunit beta-2 isoform X2

UniProtKB/TrEMBL

A0A8C0K5B0

Conserved Domains (3) summary

TIGR00860
Location:2 → 395

LIC; Cation transporter family protein

cd03558
Location:95 → 109

LGIC_ECD; Cys-loop [structural motif]

cl28912
Location:1 → 174

LGIC_ECD; extracellular domain (ECD) of Cys-loop neurotransmitter-gated ion channels (also known as ligand-gated ion channel (LGIC))