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    S1PR1 sphingosine-1-phosphate receptor 1 [ Canis lupus familiaris (dog) ]

    Gene ID: 490138, updated on 17-Aug-2024

    Summary

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    Official Symbol
    S1PR1provided by VGNC
    Official Full Name
    sphingosine-1-phosphate receptor 1provided by VGNC
    Primary source
    VGNC:VGNC:45836
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Also known as
    EDG1
    Orthologs
    human mouse all
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    Genomic context

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    See S1PR1 in Genome Data Viewer
    Location:
    chromosome: 6
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 6 NC_051810.1 (49235333..49239909, complement)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 6 NC_049227.1 (49337617..49339895, complement)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 6 NC_049266.1 (48928661..48930939, complement)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 6 NC_049747.1 (48908285..48910563, complement)

    Chromosome 6 - NC_051810.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC111096512 Neighboring gene uncharacterized LOC119872352 Neighboring gene keratin, type I cytoskeletal 18-like Neighboring gene uncharacterized LOC102153396 Neighboring gene uncharacterized LOC111096368

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Molecular phylogenetics and the origins of placental mammals. Murphy WJ, et al. Nature, 2001 Feb 1. PMID 11214319

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables sphingosine-1-phosphate receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in angiogenesis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in sphingosine-1-phosphate receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    sphingosine 1-phosphate receptor 1
    Names
    endothelial differentiation, sphingolipid G-protein-coupled receptor, 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001314114.1 → NP_001301043.1  sphingosine 1-phosphate receptor 1

      Status: PROVISIONAL

      Source sequence(s)
      KF841603
      UniProtKB/TrEMBL
      A0A8C0NP36, W5VNF7
      Conserved Domains (2) summary
      pfam00001
      Location:62 → 310
      7tm_1; 7 transmembrane receptor (rhodopsin family)
      cl21561
      Location:52 → 144
      7tm_4; Olfactory receptor

    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051810.1 Reference ROS_Cfam_1.0

      Range
      49235333..49239909 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038667612.1 → XP_038523540.1  sphingosine 1-phosphate receptor 1 isoform X1

      UniProtKB/TrEMBL
      A0A8C0NP36, A0A8C0QZ24
      Conserved Domains (1) summary
      cd15346
      Location:46 → 322
      7tmA_S1PR1_Edg1; sphingosine-1-phosphate receptor subtype 1 (S1PR1 or S1P1), also called endothelial differentiation gene 1 (Edg1), member of the class A family of seven-transmembrane G protein-coupled receptors

    2. XM_038667615.1 → XP_038523543.1  sphingosine 1-phosphate receptor 1 isoform X1

      UniProtKB/TrEMBL
      A0A8C0NP36, A0A8C0QZ24
      Conserved Domains (1) summary
      cd15346
      Location:46 → 322
      7tmA_S1PR1_Edg1; sphingosine-1-phosphate receptor subtype 1 (S1PR1 or S1P1), also called endothelial differentiation gene 1 (Edg1), member of the class A family of seven-transmembrane G protein-coupled receptors

    3. XM_038667613.1 → XP_038523541.1  sphingosine 1-phosphate receptor 1 isoform X1

      UniProtKB/TrEMBL
      A0A8C0NP36, A0A8C0QZ24
      Conserved Domains (1) summary
      cd15346
      Location:46 → 322
      7tmA_S1PR1_Edg1; sphingosine-1-phosphate receptor subtype 1 (S1PR1 or S1P1), also called endothelial differentiation gene 1 (Edg1), member of the class A family of seven-transmembrane G protein-coupled receptors

    4. XM_038667614.1 → XP_038523542.1  sphingosine 1-phosphate receptor 1 isoform X1

      UniProtKB/TrEMBL
      A0A8C0NP36, A0A8C0QZ24
      Conserved Domains (1) summary
      cd15346
      Location:46 → 322
      7tmA_S1PR1_Edg1; sphingosine-1-phosphate receptor subtype 1 (S1PR1 or S1P1), also called endothelial differentiation gene 1 (Edg1), member of the class A family of seven-transmembrane G protein-coupled receptors

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049266.1 Alternate UMICH_Zoey_3.1

      Range
      48928661..48930939 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049747.1 Alternate UNSW_CanFamBas_1.0

      Range
      48908285..48910563 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049227.1 Alternate UU_Cfam_GSD_1.0

      Range
      49337617..49339895 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

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