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    ATG4C autophagy related 4C cysteine peptidase [ Canis lupus familiaris (dog) ]

    Gene ID: 489561, updated on 17-Aug-2024

    Summary

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    Official Symbol
    ATG4Cprovided by VGNC
    Official Full Name
    autophagy related 4C cysteine peptidaseprovided by VGNC
    Primary source
    VGNC:VGNC:38224
    See related
    Ensembl:ENSCAFG00845005004
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Orthologs
    human mouse all
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    Genomic context

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    See ATG4C in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 5 NC_051809.1 (47456697..47542055, complement)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 5 NC_006587.4 (47335099..47420547, complement)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 5 NC_049226.1 (47621837..47707196, complement)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 5 NC_049265.1 (47412900..47497781, complement)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 5 NC_049746.1 (47358502..47443312, complement)

    Chromosome 5 - NC_051809.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC106558771 Neighboring gene uncharacterized LOC111095935 Neighboring gene uncharacterized LOC111095936 Neighboring gene U2 spliceosomal RNA Neighboring gene nicotinamide riboside kinase 1-like Neighboring gene dedicator of cytokinesis 7

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein-phosphatidylethanolamide deconjugating activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    cysteine protease ATG4C
    Names
    ATG4 autophagy related 4 homolog C
    XP_022274474.1
    XP_038332065.1
    XP_038332066.1
    XP_038332067.1
    XP_038332068.1
    XP_038332069.1
    XP_038332070.1
    XP_038375648.1
    XP_038375672.1
    XP_038375680.1
    XP_038375684.1
    XP_038393250.1
    XP_038393251.1
    XP_038393252.1
    XP_038393253.1
    XP_038393254.1
    XP_038393255.1
    XP_038457379.1
    XP_038457380.1
    XP_038457381.1
    XP_038457382.1
    XP_038457383.1
    XP_038457384.1
    XP_038521944.1
    XP_038521945.1
    XP_038521946.1
    XP_038521947.1
    XP_038521948.1
    XP_038521949.1
    XP_852273.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051809.1 Reference ROS_Cfam_1.0

      Range
      47456697..47542055 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038666019.1 → XP_038521947.1  cysteine protease ATG4C isoform X2

      UniProtKB/TrEMBL
      A0A8C0LUE1, A0A8I3MN07, A0A8P0P2P0
      Related
      ENSCAFP00845007100.1, ENSCAFT00845009005.1
      Conserved Domains (1) summary
      pfam03416
      Location:48 → 366
      Peptidase_C54; Peptidase family C54

    2. XM_038666018.1 → XP_038521946.1  cysteine protease ATG4C isoform X1

      UniProtKB/TrEMBL
      A0A8C0L0P5, A0A8C0LUE1, A0A8C0S777, A0A8I3MPV7
      Conserved Domains (1) summary
      pfam03416
      Location:76 → 394
      Peptidase_C54; Peptidase family C54

    3. XM_038666016.1 → XP_038521944.1  cysteine protease ATG4C isoform X1

      UniProtKB/TrEMBL
      A0A8C0L0P5, A0A8C0LUE1, A0A8C0S777, A0A8I3MPV7
      Related
      ENSCAFP00845007093.1, ENSCAFT00845008998.1
      Conserved Domains (1) summary
      pfam03416
      Location:76 → 394
      Peptidase_C54; Peptidase family C54

    4. XM_038666017.1 → XP_038521945.1  cysteine protease ATG4C isoform X1

      UniProtKB/TrEMBL
      A0A8C0L0P5, A0A8C0LUE1, A0A8C0S777, A0A8I3MPV7
      Conserved Domains (1) summary
      pfam03416
      Location:76 → 394
      Peptidase_C54; Peptidase family C54

    5. XM_038666020.1 → XP_038521948.1  cysteine protease ATG4C isoform X3

      UniProtKB/TrEMBL
      A0A8I3MS42, A0A8I3MZ28, A0A8P0TDK9
      Related
      ENSCAFP00845007090.1, ENSCAFT00845008994.1
      Conserved Domains (1) summary
      pfam03416
      Location:76 → 394
      Peptidase_C54; Peptidase family C54

    6. XM_038666021.1 → XP_038521949.1  cysteine protease ATG4C isoform X4

      UniProtKB/TrEMBL
      A0A8C0KX17
      Conserved Domains (1) summary
      pfam03416
      Location:76 → 363
      Peptidase_C54; Peptidase family C54

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049265.1 Alternate UMICH_Zoey_3.1

      Range
      47412900..47497781 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038476140.1 → XP_038332068.1  cysteine protease ATG4C isoform X2

      Conserved Domains (1) summary
      pfam03416
      Location:48 → 366
      Peptidase_C54; Peptidase family C54

    2. XM_038476139.1 → XP_038332067.1  cysteine protease ATG4C isoform X1

      Conserved Domains (1) summary
      pfam03416
      Location:76 → 394
      Peptidase_C54; Peptidase family C54

    3. XM_038476137.1 → XP_038332065.1  cysteine protease ATG4C isoform X1

      Conserved Domains (1) summary
      pfam03416
      Location:76 → 394
      Peptidase_C54; Peptidase family C54

    4. XM_038476138.1 → XP_038332066.1  cysteine protease ATG4C isoform X1

      Conserved Domains (1) summary
      pfam03416
      Location:76 → 394
      Peptidase_C54; Peptidase family C54

    5. XM_038476141.1 → XP_038332069.1  cysteine protease ATG4C isoform X3

      Conserved Domains (1) summary
      pfam03416
      Location:76 → 394
      Peptidase_C54; Peptidase family C54

    6. XM_038476142.1 → XP_038332070.1  cysteine protease ATG4C isoform X4

      Conserved Domains (1) summary
      pfam03416
      Location:76 → 363
      Peptidase_C54; Peptidase family C54

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049746.1 Alternate UNSW_CanFamBas_1.0

      Range
      47358502..47443312 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038601454.1 → XP_038457382.1  cysteine protease ATG4C isoform X2

      Conserved Domains (1) summary
      pfam03416
      Location:48 → 366
      Peptidase_C54; Peptidase family C54

    2. XM_038601453.1 → XP_038457381.1  cysteine protease ATG4C isoform X1

      Conserved Domains (1) summary
      pfam03416
      Location:76 → 394
      Peptidase_C54; Peptidase family C54

    3. XM_038601451.1 → XP_038457379.1  cysteine protease ATG4C isoform X1

      Conserved Domains (1) summary
      pfam03416
      Location:76 → 394
      Peptidase_C54; Peptidase family C54

    4. XM_038601452.1 → XP_038457380.1  cysteine protease ATG4C isoform X1

      Conserved Domains (1) summary
      pfam03416
      Location:76 → 394
      Peptidase_C54; Peptidase family C54

    5. XM_038601455.1 → XP_038457383.1  cysteine protease ATG4C isoform X3

      Conserved Domains (1) summary
      pfam03416
      Location:76 → 394
      Peptidase_C54; Peptidase family C54

    6. XM_038601456.1 → XP_038457384.1  cysteine protease ATG4C isoform X4

      Conserved Domains (1) summary
      pfam03416
      Location:76 → 363
      Peptidase_C54; Peptidase family C54

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049226.1 Alternate UU_Cfam_GSD_1.0

      Range
      47621837..47707196 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038537325.1 → XP_038393253.1  cysteine protease ATG4C isoform X2

      UniProtKB/TrEMBL
      A0A8C0LUE1, A0A8I3MN07, A0A8P0P2P0
      Conserved Domains (1) summary
      pfam03416
      Location:48 → 366
      Peptidase_C54; Peptidase family C54

    2. XM_038537324.1 → XP_038393252.1  cysteine protease ATG4C isoform X1

      UniProtKB/TrEMBL
      A0A8C0L0P5, A0A8C0LUE1, A0A8C0S777, A0A8I3MPV7
      Conserved Domains (1) summary
      pfam03416
      Location:76 → 394
      Peptidase_C54; Peptidase family C54

    3. XM_038537322.1 → XP_038393250.1  cysteine protease ATG4C isoform X1

      UniProtKB/TrEMBL
      A0A8C0L0P5, A0A8C0LUE1, A0A8C0S777, A0A8I3MPV7
      Conserved Domains (1) summary
      pfam03416
      Location:76 → 394
      Peptidase_C54; Peptidase family C54

    4. XM_038537323.1 → XP_038393251.1  cysteine protease ATG4C isoform X1

      UniProtKB/TrEMBL
      A0A8C0L0P5, A0A8C0LUE1, A0A8C0S777, A0A8I3MPV7
      Conserved Domains (1) summary
      pfam03416
      Location:76 → 394
      Peptidase_C54; Peptidase family C54

    5. XM_038537326.1 → XP_038393254.1  cysteine protease ATG4C isoform X3

      UniProtKB/TrEMBL
      A0A8I3MS42, A0A8I3MZ28, A0A8P0TDK9
      Conserved Domains (1) summary
      pfam03416
      Location:76 → 394
      Peptidase_C54; Peptidase family C54

    6. XM_038537327.1 → XP_038393255.1  cysteine protease ATG4C isoform X4

      UniProtKB/TrEMBL
      A0A8C0KX17
      Conserved Domains (1) summary
      pfam03416
      Location:76 → 363
      Peptidase_C54; Peptidase family C54

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006587.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      47335099..47420547 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038519744.1 → XP_038375672.1  cysteine protease ATG4C isoform X2

      UniProtKB/TrEMBL
      A0A8C0LUE1, A0A8I3MN07, A0A8P0P2P0
      Conserved Domains (1) summary
      pfam03416
      Location:48 → 366
      Peptidase_C54; Peptidase family C54

    2. XM_847180.6 → XP_852273.1  cysteine protease ATG4C isoform X1

      See identical proteins and their annotated locations for XP_852273.1

      UniProtKB/TrEMBL
      A0A8C0L0P5, A0A8C0LUE1, A0A8C0S777, A0A8I3MPV7
      Conserved Domains (1) summary
      pfam03416
      Location:76 → 394
      Peptidase_C54; Peptidase family C54

    3. XM_038519720.1 → XP_038375648.1  cysteine protease ATG4C isoform X1

      UniProtKB/TrEMBL
      A0A8C0L0P5, A0A8C0LUE1, A0A8C0S777, A0A8I3MPV7
      Conserved Domains (1) summary
      pfam03416
      Location:76 → 394
      Peptidase_C54; Peptidase family C54

    4. XM_022418766.2 → XP_022274474.1  cysteine protease ATG4C isoform X1

      UniProtKB/TrEMBL
      A0A8C0L0P5, A0A8C0LUE1, A0A8C0S777, A0A8I3MPV7
      Conserved Domains (1) summary
      pfam03416
      Location:76 → 394
      Peptidase_C54; Peptidase family C54

    5. XM_038519752.1 → XP_038375680.1  cysteine protease ATG4C isoform X3

      UniProtKB/TrEMBL
      A0A8I3MS42, A0A8I3MZ28, A0A8P0TDK9
      Conserved Domains (1) summary
      pfam03416
      Location:76 → 394
      Peptidase_C54; Peptidase family C54

    6. XM_038519756.1 → XP_038375684.1  cysteine protease ATG4C isoform X4

      UniProtKB/TrEMBL
      A0A8C0KX17
      Conserved Domains (1) summary
      pfam03416
      Location:76 → 363
      Peptidase_C54; Peptidase family C54
    Nucleotide Protein
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