U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination
    • Showing Current items.

    MAP2K3 mitogen-activated protein kinase kinase 3 [ Canis lupus familiaris (dog) ]

    Gene ID: 489547, updated on 17-Aug-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    MAP2K3provided by VGNC
    Official Full Name
    mitogen-activated protein kinase kinase 3provided by VGNC
    Primary source
    VGNC:VGNC:42961
    See related
    Ensembl:ENSCAFG00845026332
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Orthologs
    human mouse all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See MAP2K3 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 5 NC_051809.1 (42839802..42869464)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 5 NC_006587.4 (42870421..42900078)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 5 NC_049226.1 (42946459..42976119)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 5 NC_049265.1 (42806533..42836183)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 5 NC_049746.1 (42753555..42783186)

    Chromosome 5 - NC_051809.1Genomic Context describing neighboring genes Neighboring gene coiled-coil-helix-coiled-coil-helix domain-containing protein 10, mitochondrial-like Neighboring gene uncharacterized LOC106558821 Neighboring gene N-acetyltransferase domain containing 1 Neighboring gene uncharacterized LOC102154017 Neighboring gene potassium inwardly rectifying channel subfamily J member 12 Neighboring gene lysine-rich nucleolar protein 1-like

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Role of Src signal transduction pathways in scatter factor-mediated cellular protection. Fan S, et al. J Biol Chem, 2009 Mar 20. PMID 19047046, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

    Go to the top of the page

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables MAP kinase kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in MAPK cascade IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    dual specificity mitogen-activated protein kinase kinase 3
    XP_038331891.1
    XP_038393080.1
    XP_038457208.1
    XP_038521774.1
    XP_546666.2

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051809.1 Reference ROS_Cfam_1.0

      Range
      42839802..42869464
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038665846.1 → XP_038521774.1  dual specificity mitogen-activated protein kinase kinase 3

      UniProtKB/TrEMBL
      A0A8C0L936, A0A8C0Q0W7, A0A8C0RB66
      Related
      ENSCAFP00845036454.1, ENSCAFT00845046424.1
      Conserved Domains (1) summary
      cd06617
      Location:62 → 344
      PKc_MKK3_6; Catalytic domain of the dual-specificity Protein Kinases, Mitogen-activated protein Kinase Kinases 3 and 6

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049265.1 Alternate UMICH_Zoey_3.1

      Range
      42806533..42836183
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038475963.1 → XP_038331891.1  dual specificity mitogen-activated protein kinase kinase 3

      Conserved Domains (1) summary
      cd06617
      Location:62 → 344
      PKc_MKK3_6; Catalytic domain of the dual-specificity Protein Kinases, Mitogen-activated protein Kinase Kinases 3 and 6

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049746.1 Alternate UNSW_CanFamBas_1.0

      Range
      42753555..42783186
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038601280.1 → XP_038457208.1  dual specificity mitogen-activated protein kinase kinase 3

      Conserved Domains (1) summary
      cd06617
      Location:62 → 344
      PKc_MKK3_6; Catalytic domain of the dual-specificity Protein Kinases, Mitogen-activated protein Kinase Kinases 3 and 6

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049226.1 Alternate UU_Cfam_GSD_1.0

      Range
      42946459..42976119
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038537152.1 → XP_038393080.1  dual specificity mitogen-activated protein kinase kinase 3

      UniProtKB/TrEMBL
      A0A8C0L936, A0A8C0Q0W7, A0A8C0RB66
      Conserved Domains (1) summary
      cd06617
      Location:62 → 344
      PKc_MKK3_6; Catalytic domain of the dual-specificity Protein Kinases, Mitogen-activated protein Kinase Kinases 3 and 6

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006587.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      42870421..42900078
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_546666.6 → XP_546666.2  dual specificity mitogen-activated protein kinase kinase 3

      UniProtKB/TrEMBL
      A0A8C0L936, A0A8C0Q0W7, A0A8C0RB66
      Conserved Domains (1) summary
      cd06617
      Location:62 → 344
      PKc_MKK3_6; Catalytic domain of the dual-specificity Protein Kinases, Mitogen-activated protein Kinase Kinases 3 and 6
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials