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    DLG4 discs large MAGUK scaffold protein 4 [ Canis lupus familiaris (dog) ]

    Gene ID: 489462, updated on 5-Mar-2024

    Summary

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    Official Symbol
    DLG4provided by VGNC
    Official Full Name
    discs large MAGUK scaffold protein 4provided by VGNC
    Primary source
    VGNC:VGNC:106596
    See related
    Ensembl:ENSCAFG00845018777
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Orthologs
    human mouse all
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    Genomic context

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    See DLG4 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    24
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 5 NC_051809.1 (32271402..32294586, complement)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 5 NC_006587.4 (32303501..32327281, complement)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 5 NC_049226.1 (32372643..32395864, complement)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 5 NC_049265.1 (32236680..32259896, complement)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 5 NC_049746.1 (32195151..32218943, complement)

    Chromosome 5 - NC_051809.1Genomic Context describing neighboring genes Neighboring gene asialoglycoprotein receptor 2 Neighboring gene uncharacterized LOC119871842 Neighboring gene asialoglycoprotein receptor 1 Neighboring gene uncharacterized LOC119871843 Neighboring gene acyl-CoA dehydrogenase very long chain Neighboring gene microRNA mir-324 Neighboring gene dishevelled segment polarity protein 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables kinase binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in AMPA glutamate receptor clustering IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in chemical synaptic transmission IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in postsynaptic neurotransmitter receptor diffusion trapping IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in neuromuscular junction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in neuron projection IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in postsynaptic density membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    disks large homolog 4

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051809.1 Reference ROS_Cfam_1.0

      Range
      32271402..32294586 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038665348.1 → XP_038521276.1  disks large homolog 4 isoform X4

      UniProtKB/TrEMBL
      A0A8C0MXR4, A0A8I3P9L3
      Conserved Domains (6) summary
      cd12030
      Location:463 → 528
      SH3_DLG4; Src Homology 3 domain of Disks Large homolog 4
      smart00228
      Location:343 → 427
      PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
      pfam00595
      Location:98 → 182
      PDZ; PDZ domain (Also known as DHR or GLGF)
      pfam00625
      Location:566 → 744
      Guanylate_kin; Guanylate kinase
      pfam10600
      Location:278 → 345
      PDZ_assoc; PDZ-associated domain of NMDA receptors
      pfam10608
      Location:10 → 97
      MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK

    2. XM_038665347.1 → XP_038521275.1  disks large homolog 4 isoform X3

      UniProtKB/TrEMBL
      A0A8C0PZ14, A0A8I3S101
      Related
      ENSCAFP00845026638.1, ENSCAFT00845034033.1
      Conserved Domains (7) summary
      cd12030
      Location:522 → 587
      SH3_DLG4; Src Homology 3 domain of Disks Large homolog 4
      smart00228
      Location:402 → 486
      PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
      pfam00595
      Location:157 → 241
      PDZ; PDZ domain (Also known as DHR or GLGF)
      pfam00625
      Location:625 → 803
      Guanylate_kin; Guanylate kinase
      pfam10600
      Location:337 → 404
      PDZ_assoc; PDZ-associated domain of NMDA receptors
      pfam10608
      Location:70 → 156
      MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK
      cl02672
      Location:42 → 63
      L27; L27 domain

    3. XM_038665344.1 → XP_038521272.1  disks large homolog 4 isoform X2

      UniProtKB/TrEMBL
      A0A8C0PZ14, A0A8I3S101
      Conserved Domains (7) summary
      cd12030
      Location:556 → 621
      SH3_DLG4; Src Homology 3 domain of Disks Large homolog 4
      smart00228
      Location:436 → 520
      PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
      pfam00595
      Location:191 → 275
      PDZ; PDZ domain (Also known as DHR or GLGF)
      pfam00625
      Location:659 → 837
      Guanylate_kin; Guanylate kinase
      pfam10600
      Location:371 → 438
      PDZ_assoc; PDZ-associated domain of NMDA receptors
      pfam10608
      Location:104 → 190
      MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK
      cl02672
      Location:76 → 97
      L27; L27 domain

    4. XM_038665346.1 → XP_038521274.1  disks large homolog 4 isoform X1

      UniProtKB/TrEMBL
      A0A8C0MXR4, A0A8I3P9L3
      Conserved Domains (5) summary
      cd12030
      Location:370 → 435
      SH3_DLG4; Src Homology 3 domain of Disks Large homolog 4
      smart00228
      Location:250 → 334
      PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
      pfam00595
      Location:5 → 89
      PDZ; PDZ domain (Also known as DHR or GLGF)
      pfam00625
      Location:473 → 651
      Guanylate_kin; Guanylate kinase
      pfam10600
      Location:185 → 252
      PDZ_assoc; PDZ-associated domain of NMDA receptors

    5. XM_038665343.1 → XP_038521271.1  disks large homolog 4 isoform X1

      UniProtKB/TrEMBL
      A0A8C0MXR4, A0A8I3P9L3
      Conserved Domains (5) summary
      cd12030
      Location:370 → 435
      SH3_DLG4; Src Homology 3 domain of Disks Large homolog 4
      smart00228
      Location:250 → 334
      PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
      pfam00595
      Location:5 → 89
      PDZ; PDZ domain (Also known as DHR or GLGF)
      pfam00625
      Location:473 → 651
      Guanylate_kin; Guanylate kinase
      pfam10600
      Location:185 → 252
      PDZ_assoc; PDZ-associated domain of NMDA receptors

    6. XM_038665345.1 → XP_038521273.1  disks large homolog 4 isoform X1

      UniProtKB/TrEMBL
      A0A8C0MXR4, A0A8I3P9L3
      Conserved Domains (5) summary
      cd12030
      Location:370 → 435
      SH3_DLG4; Src Homology 3 domain of Disks Large homolog 4
      smart00228
      Location:250 → 334
      PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
      pfam00595
      Location:5 → 89
      PDZ; PDZ domain (Also known as DHR or GLGF)
      pfam00625
      Location:473 → 651
      Guanylate_kin; Guanylate kinase
      pfam10600
      Location:185 → 252
      PDZ_assoc; PDZ-associated domain of NMDA receptors

    7. XM_038665350.1 → XP_038521278.1  disks large homolog 4 isoform X6

      UniProtKB/TrEMBL
      A0A8C0MXR4, A0A8I3P9L3
      Conserved Domains (6) summary
      cd12030
      Location:427 → 492
      SH3_DLG4; Src Homology 3 domain of Disks Large homolog 4
      smart00228
      Location:307 → 391
      PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
      pfam00595
      Location:62 → 146
      PDZ; PDZ domain (Also known as DHR or GLGF)
      pfam00625
      Location:530 → 708
      Guanylate_kin; Guanylate kinase
      pfam10600
      Location:242 → 309
      PDZ_assoc; PDZ-associated domain of NMDA receptors
      pfam10608
      Location:10 → 61
      MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK

    8. XM_038665349.1 → XP_038521277.1  disks large homolog 4 isoform X5

      UniProtKB/TrEMBL
      A0A8C0KDZ9, A0A8C0MXR4, A0A8C0NAW3, A0A8I3P9L3, A0A8I3PGP6
      Related
      ENSCAFP00845026767.1, ENSCAFT00845034190.1
      Conserved Domains (6) summary
      cd12030
      Location:430 → 495
      SH3_DLG4; Src Homology 3 domain of Disks Large homolog 4
      smart00228
      Location:310 → 394
      PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
      pfam00595
      Location:65 → 149
      PDZ; PDZ domain (Also known as DHR or GLGF)
      pfam00625
      Location:533 → 711
      Guanylate_kin; Guanylate kinase
      pfam10600
      Location:245 → 312
      PDZ_assoc; PDZ-associated domain of NMDA receptors
      pfam10608
      Location:10 → 64
      MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK

    9. XM_038665352.1 → XP_038521280.1  disks large homolog 4 isoform X8

      UniProtKB/TrEMBL
      A0A8C0MXR4, A0A8I3P9L3
      Related
      ENSCAFP00845026873.1, ENSCAFT00845034329.1
      Conserved Domains (6) summary
      cd12030
      Location:405 → 470
      SH3_DLG4; Src Homology 3 domain of Disks Large homolog 4
      smart00228
      Location:285 → 369
      PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
      pfam00595
      Location:40 → 124
      PDZ; PDZ domain (Also known as DHR or GLGF)
      pfam00625
      Location:508 → 686
      Guanylate_kin; Guanylate kinase
      pfam10600
      Location:220 → 287
      PDZ_assoc; PDZ-associated domain of NMDA receptors
      pfam10608
      Location:7 → 39
      MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK

    10. XM_038665351.1 → XP_038521279.1  disks large homolog 4 isoform X7

      UniProtKB/TrEMBL
      A0A8C0MXR4, A0A8I3P9L3
      Conserved Domains (6) summary
      cd12030
      Location:408 → 473
      SH3_DLG4; Src Homology 3 domain of Disks Large homolog 4
      smart00228
      Location:288 → 372
      PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
      pfam00595
      Location:43 → 127
      PDZ; PDZ domain (Also known as DHR or GLGF)
      pfam00625
      Location:511 → 689
      Guanylate_kin; Guanylate kinase
      pfam10600
      Location:223 → 290
      PDZ_assoc; PDZ-associated domain of NMDA receptors
      pfam10608
      Location:7 → 42
      MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK

    11. XM_038665353.1 → XP_038521281.1  disks large homolog 4 isoform X9

      Conserved Domains (4) summary
      cd12030
      Location:145 → 210
      SH3_DLG4; Src Homology 3 domain of Disks Large homolog 4
      smart00228
      Location:25 → 109
      PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
      pfam00625
      Location:248 → 426
      Guanylate_kin; Guanylate kinase
      pfam10600
      Location:1 → 27
      PDZ_assoc; PDZ-associated domain of NMDA receptors

    RNA

    1. XR_005427064.1 RNA Sequence

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049265.1 Alternate UMICH_Zoey_3.1

      Range
      32236680..32259896 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038475453.1 → XP_038331381.1  disks large homolog 4 isoform X4

      Conserved Domains (6) summary
      cd12030
      Location:463 → 528
      SH3_DLG4; Src Homology 3 domain of Disks Large homolog 4
      smart00228
      Location:343 → 427
      PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
      pfam00595
      Location:98 → 182
      PDZ; PDZ domain (Also known as DHR or GLGF)
      pfam00625
      Location:566 → 744
      Guanylate_kin; Guanylate kinase
      pfam10600
      Location:278 → 345
      PDZ_assoc; PDZ-associated domain of NMDA receptors
      pfam10608
      Location:10 → 97
      MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK

    2. XM_038475456.1 → XP_038331384.1  disks large homolog 4 isoform X6

      Conserved Domains (6) summary
      cd12030
      Location:427 → 492
      SH3_DLG4; Src Homology 3 domain of Disks Large homolog 4
      smart00228
      Location:307 → 391
      PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
      pfam00595
      Location:62 → 146
      PDZ; PDZ domain (Also known as DHR or GLGF)
      pfam00625
      Location:530 → 708
      Guanylate_kin; Guanylate kinase
      pfam10600
      Location:242 → 309
      PDZ_assoc; PDZ-associated domain of NMDA receptors
      pfam10608
      Location:10 → 61
      MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK

    3. XM_038475454.1 → XP_038331382.1  disks large homolog 4 isoform X5

      Conserved Domains (6) summary
      cd12030
      Location:430 → 495
      SH3_DLG4; Src Homology 3 domain of Disks Large homolog 4
      smart00228
      Location:310 → 394
      PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
      pfam00595
      Location:65 → 149
      PDZ; PDZ domain (Also known as DHR or GLGF)
      pfam00625
      Location:533 → 711
      Guanylate_kin; Guanylate kinase
      pfam10600
      Location:245 → 312
      PDZ_assoc; PDZ-associated domain of NMDA receptors
      pfam10608
      Location:10 → 64
      MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK

    4. XM_038475459.1 → XP_038331387.1  disks large homolog 4 isoform X9

      Conserved Domains (4) summary
      cd12030
      Location:145 → 210
      SH3_DLG4; Src Homology 3 domain of Disks Large homolog 4
      smart00228
      Location:25 → 109
      PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
      pfam00625
      Location:248 → 426
      Guanylate_kin; Guanylate kinase
      pfam10600
      Location:1 → 27
      PDZ_assoc; PDZ-associated domain of NMDA receptors

    5. XM_038475452.1 → XP_038331380.1  disks large homolog 4 isoform X3

      Conserved Domains (7) summary
      cd12030
      Location:522 → 587
      SH3_DLG4; Src Homology 3 domain of Disks Large homolog 4
      smart00228
      Location:402 → 486
      PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
      pfam00595
      Location:157 → 241
      PDZ; PDZ domain (Also known as DHR or GLGF)
      pfam00625
      Location:625 → 803
      Guanylate_kin; Guanylate kinase
      pfam10600
      Location:337 → 404
      PDZ_assoc; PDZ-associated domain of NMDA receptors
      pfam10608
      Location:70 → 156
      MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK
      cl02672
      Location:42 → 63
      L27; L27 domain

    6. XM_038475449.1 → XP_038331377.1  disks large homolog 4 isoform X2

      Conserved Domains (7) summary
      cd12030
      Location:556 → 621
      SH3_DLG4; Src Homology 3 domain of Disks Large homolog 4
      smart00228
      Location:436 → 520
      PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
      pfam00595
      Location:191 → 275
      PDZ; PDZ domain (Also known as DHR or GLGF)
      pfam00625
      Location:659 → 837
      Guanylate_kin; Guanylate kinase
      pfam10600
      Location:371 → 438
      PDZ_assoc; PDZ-associated domain of NMDA receptors
      pfam10608
      Location:104 → 190
      MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK
      cl02672
      Location:76 → 97
      L27; L27 domain

    7. XM_038475451.1 → XP_038331379.1  disks large homolog 4 isoform X1

      Conserved Domains (5) summary
      cd12030
      Location:370 → 435
      SH3_DLG4; Src Homology 3 domain of Disks Large homolog 4
      smart00228
      Location:250 → 334
      PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
      pfam00595
      Location:5 → 89
      PDZ; PDZ domain (Also known as DHR or GLGF)
      pfam00625
      Location:473 → 651
      Guanylate_kin; Guanylate kinase
      pfam10600
      Location:185 → 252
      PDZ_assoc; PDZ-associated domain of NMDA receptors

    8. XM_038475448.1 → XP_038331376.1  disks large homolog 4 isoform X1

      Conserved Domains (5) summary
      cd12030
      Location:370 → 435
      SH3_DLG4; Src Homology 3 domain of Disks Large homolog 4
      smart00228
      Location:250 → 334
      PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
      pfam00595
      Location:5 → 89
      PDZ; PDZ domain (Also known as DHR or GLGF)
      pfam00625
      Location:473 → 651
      Guanylate_kin; Guanylate kinase
      pfam10600
      Location:185 → 252
      PDZ_assoc; PDZ-associated domain of NMDA receptors

    9. XM_038475450.1 → XP_038331378.1  disks large homolog 4 isoform X1

      Conserved Domains (5) summary
      cd12030
      Location:370 → 435
      SH3_DLG4; Src Homology 3 domain of Disks Large homolog 4
      smart00228
      Location:250 → 334
      PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
      pfam00595
      Location:5 → 89
      PDZ; PDZ domain (Also known as DHR or GLGF)
      pfam00625
      Location:473 → 651
      Guanylate_kin; Guanylate kinase
      pfam10600
      Location:185 → 252
      PDZ_assoc; PDZ-associated domain of NMDA receptors

    10. XM_038475458.1 → XP_038331386.1  disks large homolog 4 isoform X8

      Conserved Domains (6) summary
      cd12030
      Location:405 → 470
      SH3_DLG4; Src Homology 3 domain of Disks Large homolog 4
      smart00228
      Location:285 → 369
      PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
      pfam00595
      Location:40 → 124
      PDZ; PDZ domain (Also known as DHR or GLGF)
      pfam00625
      Location:508 → 686
      Guanylate_kin; Guanylate kinase
      pfam10600
      Location:220 → 287
      PDZ_assoc; PDZ-associated domain of NMDA receptors
      pfam10608
      Location:7 → 39
      MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK

    11. XM_038475457.1 → XP_038331385.1  disks large homolog 4 isoform X7

      Conserved Domains (6) summary
      cd12030
      Location:408 → 473
      SH3_DLG4; Src Homology 3 domain of Disks Large homolog 4
      smart00228
      Location:288 → 372
      PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
      pfam00595
      Location:43 → 127
      PDZ; PDZ domain (Also known as DHR or GLGF)
      pfam00625
      Location:511 → 689
      Guanylate_kin; Guanylate kinase
      pfam10600
      Location:223 → 290
      PDZ_assoc; PDZ-associated domain of NMDA receptors
      pfam10608
      Location:7 → 42
      MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK

    RNA

    1. XR_005325581.1 RNA Sequence

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049746.1 Alternate UNSW_CanFamBas_1.0

      Range
      32195151..32218943 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038600812.1 → XP_038456740.1  disks large homolog 4 isoform X3

      Conserved Domains (7) summary
      cd12030
      Location:522 → 587
      SH3_DLG4; Src Homology 3 domain of Disks Large homolog 4
      smart00228
      Location:402 → 486
      PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
      pfam00595
      Location:157 → 241
      PDZ; PDZ domain (Also known as DHR or GLGF)
      pfam00625
      Location:625 → 803
      Guanylate_kin; Guanylate kinase
      pfam10600
      Location:337 → 404
      PDZ_assoc; PDZ-associated domain of NMDA receptors
      pfam10608
      Location:70 → 156
      MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK
      cl02672
      Location:42 → 63
      L27; L27 domain

    2. XM_038600809.1 → XP_038456737.1  disks large homolog 4 isoform X2

      Conserved Domains (7) summary
      cd12030
      Location:556 → 621
      SH3_DLG4; Src Homology 3 domain of Disks Large homolog 4
      smart00228
      Location:436 → 520
      PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
      pfam00595
      Location:191 → 275
      PDZ; PDZ domain (Also known as DHR or GLGF)
      pfam00625
      Location:659 → 837
      Guanylate_kin; Guanylate kinase
      pfam10600
      Location:371 → 438
      PDZ_assoc; PDZ-associated domain of NMDA receptors
      pfam10608
      Location:104 → 190
      MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK
      cl02672
      Location:76 → 97
      L27; L27 domain

    3. XM_038600811.1 → XP_038456739.1  disks large homolog 4 isoform X1

      Conserved Domains (5) summary
      cd12030
      Location:370 → 435
      SH3_DLG4; Src Homology 3 domain of Disks Large homolog 4
      smart00228
      Location:250 → 334
      PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
      pfam00595
      Location:5 → 89
      PDZ; PDZ domain (Also known as DHR or GLGF)
      pfam00625
      Location:473 → 651
      Guanylate_kin; Guanylate kinase
      pfam10600
      Location:185 → 252
      PDZ_assoc; PDZ-associated domain of NMDA receptors

    4. XM_038600808.1 → XP_038456736.1  disks large homolog 4 isoform X1

      Conserved Domains (5) summary
      cd12030
      Location:370 → 435
      SH3_DLG4; Src Homology 3 domain of Disks Large homolog 4
      smart00228
      Location:250 → 334
      PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
      pfam00595
      Location:5 → 89
      PDZ; PDZ domain (Also known as DHR or GLGF)
      pfam00625
      Location:473 → 651
      Guanylate_kin; Guanylate kinase
      pfam10600
      Location:185 → 252
      PDZ_assoc; PDZ-associated domain of NMDA receptors

    5. XM_038600810.1 → XP_038456738.1  disks large homolog 4 isoform X1

      Conserved Domains (5) summary
      cd12030
      Location:370 → 435
      SH3_DLG4; Src Homology 3 domain of Disks Large homolog 4
      smart00228
      Location:250 → 334
      PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
      pfam00595
      Location:5 → 89
      PDZ; PDZ domain (Also known as DHR or GLGF)
      pfam00625
      Location:473 → 651
      Guanylate_kin; Guanylate kinase
      pfam10600
      Location:185 → 252
      PDZ_assoc; PDZ-associated domain of NMDA receptors

    6. XM_038600813.1 → XP_038456741.1  disks large homolog 4 isoform X4

      Conserved Domains (6) summary
      cd12030
      Location:463 → 528
      SH3_DLG4; Src Homology 3 domain of Disks Large homolog 4
      smart00228
      Location:343 → 427
      PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
      pfam00595
      Location:98 → 182
      PDZ; PDZ domain (Also known as DHR or GLGF)
      pfam00625
      Location:566 → 744
      Guanylate_kin; Guanylate kinase
      pfam10600
      Location:278 → 345
      PDZ_assoc; PDZ-associated domain of NMDA receptors
      pfam10608
      Location:10 → 97
      MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK

    7. XM_038600815.1 → XP_038456743.1  disks large homolog 4 isoform X6

      Conserved Domains (6) summary
      cd12030
      Location:427 → 492
      SH3_DLG4; Src Homology 3 domain of Disks Large homolog 4
      smart00228
      Location:307 → 391
      PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
      pfam00595
      Location:62 → 146
      PDZ; PDZ domain (Also known as DHR or GLGF)
      pfam00625
      Location:530 → 708
      Guanylate_kin; Guanylate kinase
      pfam10600
      Location:242 → 309
      PDZ_assoc; PDZ-associated domain of NMDA receptors
      pfam10608
      Location:10 → 61
      MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK

    8. XM_038600814.1 → XP_038456742.1  disks large homolog 4 isoform X5

      Conserved Domains (6) summary
      cd12030
      Location:430 → 495
      SH3_DLG4; Src Homology 3 domain of Disks Large homolog 4
      smart00228
      Location:310 → 394
      PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
      pfam00595
      Location:65 → 149
      PDZ; PDZ domain (Also known as DHR or GLGF)
      pfam00625
      Location:533 → 711
      Guanylate_kin; Guanylate kinase
      pfam10600
      Location:245 → 312
      PDZ_assoc; PDZ-associated domain of NMDA receptors
      pfam10608
      Location:10 → 64
      MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK

    9. XM_038600817.1 → XP_038456745.1  disks large homolog 4 isoform X8

      Conserved Domains (6) summary
      cd12030
      Location:405 → 470
      SH3_DLG4; Src Homology 3 domain of Disks Large homolog 4
      smart00228
      Location:285 → 369
      PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
      pfam00595
      Location:40 → 124
      PDZ; PDZ domain (Also known as DHR or GLGF)
      pfam00625
      Location:508 → 686
      Guanylate_kin; Guanylate kinase
      pfam10600
      Location:220 → 287
      PDZ_assoc; PDZ-associated domain of NMDA receptors
      pfam10608
      Location:7 → 39
      MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK

    10. XM_038600816.1 → XP_038456744.1  disks large homolog 4 isoform X7

      Conserved Domains (6) summary
      cd12030
      Location:408 → 473
      SH3_DLG4; Src Homology 3 domain of Disks Large homolog 4
      smart00228
      Location:288 → 372
      PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
      pfam00595
      Location:43 → 127
      PDZ; PDZ domain (Also known as DHR or GLGF)
      pfam00625
      Location:511 → 689
      Guanylate_kin; Guanylate kinase
      pfam10600
      Location:223 → 290
      PDZ_assoc; PDZ-associated domain of NMDA receptors
      pfam10608
      Location:7 → 42
      MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK

    11. XM_038600818.1 → XP_038456746.1  disks large homolog 4 isoform X9

      Conserved Domains (4) summary
      cd12030
      Location:145 → 210
      SH3_DLG4; Src Homology 3 domain of Disks Large homolog 4
      smart00228
      Location:25 → 109
      PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
      pfam00625
      Location:248 → 426
      Guanylate_kin; Guanylate kinase
      pfam10600
      Location:1 → 27
      PDZ_assoc; PDZ-associated domain of NMDA receptors

    RNA

    1. XR_005394004.1 RNA Sequence

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049226.1 Alternate UU_Cfam_GSD_1.0

      Range
      32372643..32395864 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038536622.1 → XP_038392550.1  disks large homolog 4 isoform X4

      UniProtKB/TrEMBL
      A0A8C0MXR4, A0A8I3P9L3
      Conserved Domains (6) summary
      cd12030
      Location:463 → 528
      SH3_DLG4; Src Homology 3 domain of Disks Large homolog 4
      smart00228
      Location:343 → 427
      PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
      pfam00595
      Location:98 → 182
      PDZ; PDZ domain (Also known as DHR or GLGF)
      pfam00625
      Location:566 → 744
      Guanylate_kin; Guanylate kinase
      pfam10600
      Location:278 → 345
      PDZ_assoc; PDZ-associated domain of NMDA receptors
      pfam10608
      Location:10 → 97
      MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK

    2. XM_038536624.1 → XP_038392552.1  disks large homolog 4 isoform X6

      UniProtKB/TrEMBL
      A0A8C0MXR4, A0A8I3P9L3
      Conserved Domains (6) summary
      cd12030
      Location:427 → 492
      SH3_DLG4; Src Homology 3 domain of Disks Large homolog 4
      smart00228
      Location:307 → 391
      PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
      pfam00595
      Location:62 → 146
      PDZ; PDZ domain (Also known as DHR or GLGF)
      pfam00625
      Location:530 → 708
      Guanylate_kin; Guanylate kinase
      pfam10600
      Location:242 → 309
      PDZ_assoc; PDZ-associated domain of NMDA receptors
      pfam10608
      Location:10 → 61
      MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK

    3. XM_038536623.1 → XP_038392551.1  disks large homolog 4 isoform X5

      UniProtKB/TrEMBL
      A0A8C0KDZ9, A0A8C0MXR4, A0A8C0NAW3, A0A8I3P9L3, A0A8I3PGP6
      Conserved Domains (6) summary
      cd12030
      Location:430 → 495
      SH3_DLG4; Src Homology 3 domain of Disks Large homolog 4
      smart00228
      Location:310 → 394
      PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
      pfam00595
      Location:65 → 149
      PDZ; PDZ domain (Also known as DHR or GLGF)
      pfam00625
      Location:533 → 711
      Guanylate_kin; Guanylate kinase
      pfam10600
      Location:245 → 312
      PDZ_assoc; PDZ-associated domain of NMDA receptors
      pfam10608
      Location:10 → 64
      MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK

    4. XM_038536627.1 → XP_038392555.1  disks large homolog 4 isoform X9

      Conserved Domains (4) summary
      cd12030
      Location:145 → 210
      SH3_DLG4; Src Homology 3 domain of Disks Large homolog 4
      smart00228
      Location:25 → 109
      PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
      pfam00625
      Location:248 → 426
      Guanylate_kin; Guanylate kinase
      pfam10600
      Location:1 → 27
      PDZ_assoc; PDZ-associated domain of NMDA receptors

    5. XM_038536621.1 → XP_038392549.1  disks large homolog 4 isoform X3

      UniProtKB/TrEMBL
      A0A8C0PZ14, A0A8I3S101
      Conserved Domains (7) summary
      cd12030
      Location:522 → 587
      SH3_DLG4; Src Homology 3 domain of Disks Large homolog 4
      smart00228
      Location:402 → 486
      PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
      pfam00595
      Location:157 → 241
      PDZ; PDZ domain (Also known as DHR or GLGF)
      pfam00625
      Location:625 → 803
      Guanylate_kin; Guanylate kinase
      pfam10600
      Location:337 → 404
      PDZ_assoc; PDZ-associated domain of NMDA receptors
      pfam10608
      Location:70 → 156
      MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK
      cl02672
      Location:42 → 63
      L27; L27 domain

    6. XM_038536617.1 → XP_038392545.1  disks large homolog 4 isoform X2

      UniProtKB/TrEMBL
      A0A8C0PZ14, A0A8I3S101
      Conserved Domains (7) summary
      cd12030
      Location:556 → 621
      SH3_DLG4; Src Homology 3 domain of Disks Large homolog 4
      smart00228
      Location:436 → 520
      PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
      pfam00595
      Location:191 → 275
      PDZ; PDZ domain (Also known as DHR or GLGF)
      pfam00625
      Location:659 → 837
      Guanylate_kin; Guanylate kinase
      pfam10600
      Location:371 → 438
      PDZ_assoc; PDZ-associated domain of NMDA receptors
      pfam10608
      Location:104 → 190
      MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK
      cl02672
      Location:76 → 97
      L27; L27 domain

    7. XM_038536619.1 → XP_038392547.1  disks large homolog 4 isoform X1

      UniProtKB/TrEMBL
      A0A8C0MXR4, A0A8I3P9L3
      Conserved Domains (5) summary
      cd12030
      Location:370 → 435
      SH3_DLG4; Src Homology 3 domain of Disks Large homolog 4
      smart00228
      Location:250 → 334
      PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
      pfam00595
      Location:5 → 89
      PDZ; PDZ domain (Also known as DHR or GLGF)
      pfam00625
      Location:473 → 651
      Guanylate_kin; Guanylate kinase
      pfam10600
      Location:185 → 252
      PDZ_assoc; PDZ-associated domain of NMDA receptors

    8. XM_038536616.1 → XP_038392544.1  disks large homolog 4 isoform X1

      UniProtKB/TrEMBL
      A0A8C0MXR4, A0A8I3P9L3
      Conserved Domains (5) summary
      cd12030
      Location:370 → 435
      SH3_DLG4; Src Homology 3 domain of Disks Large homolog 4
      smart00228
      Location:250 → 334
      PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
      pfam00595
      Location:5 → 89
      PDZ; PDZ domain (Also known as DHR or GLGF)
      pfam00625
      Location:473 → 651
      Guanylate_kin; Guanylate kinase
      pfam10600
      Location:185 → 252
      PDZ_assoc; PDZ-associated domain of NMDA receptors

    9. XM_038536618.1 → XP_038392546.1  disks large homolog 4 isoform X1

      UniProtKB/TrEMBL
      A0A8C0MXR4, A0A8I3P9L3
      Conserved Domains (5) summary
      cd12030
      Location:370 → 435
      SH3_DLG4; Src Homology 3 domain of Disks Large homolog 4
      smart00228
      Location:250 → 334
      PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
      pfam00595
      Location:5 → 89
      PDZ; PDZ domain (Also known as DHR or GLGF)
      pfam00625
      Location:473 → 651
      Guanylate_kin; Guanylate kinase
      pfam10600
      Location:185 → 252
      PDZ_assoc; PDZ-associated domain of NMDA receptors

    10. XM_038536626.1 → XP_038392554.1  disks large homolog 4 isoform X8

      UniProtKB/TrEMBL
      A0A8C0MXR4, A0A8I3P9L3
      Conserved Domains (6) summary
      cd12030
      Location:405 → 470
      SH3_DLG4; Src Homology 3 domain of Disks Large homolog 4
      smart00228
      Location:285 → 369
      PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
      pfam00595
      Location:40 → 124
      PDZ; PDZ domain (Also known as DHR or GLGF)
      pfam00625
      Location:508 → 686
      Guanylate_kin; Guanylate kinase
      pfam10600
      Location:220 → 287
      PDZ_assoc; PDZ-associated domain of NMDA receptors
      pfam10608
      Location:7 → 39
      MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK

    11. XM_038536625.1 → XP_038392553.1  disks large homolog 4 isoform X7

      UniProtKB/TrEMBL
      A0A8C0MXR4, A0A8I3P9L3
      Conserved Domains (6) summary
      cd12030
      Location:408 → 473
      SH3_DLG4; Src Homology 3 domain of Disks Large homolog 4
      smart00228
      Location:288 → 372
      PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
      pfam00595
      Location:43 → 127
      PDZ; PDZ domain (Also known as DHR or GLGF)
      pfam00625
      Location:511 → 689
      Guanylate_kin; Guanylate kinase
      pfam10600
      Location:223 → 290
      PDZ_assoc; PDZ-associated domain of NMDA receptors
      pfam10608
      Location:7 → 42
      MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK

    RNA

    1. XR_005359455.1 RNA Sequence

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006587.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      32303501..32327281 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038514580.1 → XP_038370508.1  disks large homolog 4 isoform X3

      UniProtKB/TrEMBL
      A0A8C0PZ14, A0A8I3S101
      Conserved Domains (7) summary
      cd12030
      Location:522 → 587
      SH3_DLG4; Src Homology 3 domain of Disks Large homolog 4
      smart00228
      Location:402 → 486
      PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
      pfam00595
      Location:157 → 241
      PDZ; PDZ domain (Also known as DHR or GLGF)
      pfam00625
      Location:625 → 803
      Guanylate_kin; Guanylate kinase
      pfam10600
      Location:337 → 404
      PDZ_assoc; PDZ-associated domain of NMDA receptors
      pfam10608
      Location:70 → 156
      MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK
      cl02672
      Location:42 → 63
      L27; L27 domain

    2. XM_038514558.1 → XP_038370486.1  disks large homolog 4 isoform X2

      UniProtKB/TrEMBL
      A0A8C0PZ14, A0A8I3S101
      Conserved Domains (7) summary
      cd12030
      Location:556 → 621
      SH3_DLG4; Src Homology 3 domain of Disks Large homolog 4
      smart00228
      Location:436 → 520
      PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
      pfam00595
      Location:191 → 275
      PDZ; PDZ domain (Also known as DHR or GLGF)
      pfam00625
      Location:659 → 837
      Guanylate_kin; Guanylate kinase
      pfam10600
      Location:371 → 438
      PDZ_assoc; PDZ-associated domain of NMDA receptors
      pfam10608
      Location:104 → 190
      MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK
      cl02672
      Location:76 → 97
      L27; L27 domain

    3. XM_038514570.1 → XP_038370498.1  disks large homolog 4 isoform X1

      UniProtKB/TrEMBL
      A0A8C0MXR4, A0A8I3P9L3
      Conserved Domains (5) summary
      cd12030
      Location:370 → 435
      SH3_DLG4; Src Homology 3 domain of Disks Large homolog 4
      smart00228
      Location:250 → 334
      PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
      pfam00595
      Location:5 → 89
      PDZ; PDZ domain (Also known as DHR or GLGF)
      pfam00625
      Location:473 → 651
      Guanylate_kin; Guanylate kinase
      pfam10600
      Location:185 → 252
      PDZ_assoc; PDZ-associated domain of NMDA receptors

    4. XM_038514553.1 → XP_038370481.1  disks large homolog 4 isoform X1

      UniProtKB/TrEMBL
      A0A8C0MXR4, A0A8I3P9L3
      Conserved Domains (5) summary
      cd12030
      Location:370 → 435
      SH3_DLG4; Src Homology 3 domain of Disks Large homolog 4
      smart00228
      Location:250 → 334
      PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
      pfam00595
      Location:5 → 89
      PDZ; PDZ domain (Also known as DHR or GLGF)
      pfam00625
      Location:473 → 651
      Guanylate_kin; Guanylate kinase
      pfam10600
      Location:185 → 252
      PDZ_assoc; PDZ-associated domain of NMDA receptors

    5. XM_038514561.1 → XP_038370489.1  disks large homolog 4 isoform X1

      UniProtKB/TrEMBL
      A0A8C0MXR4, A0A8I3P9L3
      Conserved Domains (5) summary
      cd12030
      Location:370 → 435
      SH3_DLG4; Src Homology 3 domain of Disks Large homolog 4
      smart00228
      Location:250 → 334
      PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
      pfam00595
      Location:5 → 89
      PDZ; PDZ domain (Also known as DHR or GLGF)
      pfam00625
      Location:473 → 651
      Guanylate_kin; Guanylate kinase
      pfam10600
      Location:185 → 252
      PDZ_assoc; PDZ-associated domain of NMDA receptors

    6. XM_038514587.1 → XP_038370515.1  disks large homolog 4 isoform X4

      UniProtKB/TrEMBL
      A0A8C0MXR4, A0A8I3P9L3
      Conserved Domains (6) summary
      cd12030
      Location:463 → 528
      SH3_DLG4; Src Homology 3 domain of Disks Large homolog 4
      smart00228
      Location:343 → 427
      PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
      pfam00595
      Location:98 → 182
      PDZ; PDZ domain (Also known as DHR or GLGF)
      pfam00625
      Location:566 → 744
      Guanylate_kin; Guanylate kinase
      pfam10600
      Location:278 → 345
      PDZ_assoc; PDZ-associated domain of NMDA receptors
      pfam10608
      Location:10 → 97
      MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK

    7. XM_038514604.1 → XP_038370532.1  disks large homolog 4 isoform X6

      UniProtKB/TrEMBL
      A0A8C0MXR4, A0A8I3P9L3
      Conserved Domains (6) summary
      cd12030
      Location:427 → 492
      SH3_DLG4; Src Homology 3 domain of Disks Large homolog 4
      smart00228
      Location:307 → 391
      PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
      pfam00595
      Location:62 → 146
      PDZ; PDZ domain (Also known as DHR or GLGF)
      pfam00625
      Location:530 → 708
      Guanylate_kin; Guanylate kinase
      pfam10600
      Location:242 → 309
      PDZ_assoc; PDZ-associated domain of NMDA receptors
      pfam10608
      Location:10 → 61
      MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK

    8. XM_038514597.1 → XP_038370525.1  disks large homolog 4 isoform X5

      UniProtKB/TrEMBL
      A0A8C0KDZ9, A0A8C0MXR4, A0A8C0NAW3, A0A8I3P9L3, A0A8I3PGP6
      Conserved Domains (6) summary
      cd12030
      Location:430 → 495
      SH3_DLG4; Src Homology 3 domain of Disks Large homolog 4
      smart00228
      Location:310 → 394
      PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
      pfam00595
      Location:65 → 149
      PDZ; PDZ domain (Also known as DHR or GLGF)
      pfam00625
      Location:533 → 711
      Guanylate_kin; Guanylate kinase
      pfam10600
      Location:245 → 312
      PDZ_assoc; PDZ-associated domain of NMDA receptors
      pfam10608
      Location:10 → 64
      MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK

    9. XM_038514626.1 → XP_038370554.1  disks large homolog 4 isoform X8

      UniProtKB/TrEMBL
      A0A8C0MXR4, A0A8I3P9L3
      Conserved Domains (6) summary
      cd12030
      Location:405 → 470
      SH3_DLG4; Src Homology 3 domain of Disks Large homolog 4
      smart00228
      Location:285 → 369
      PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
      pfam00595
      Location:40 → 124
      PDZ; PDZ domain (Also known as DHR or GLGF)
      pfam00625
      Location:508 → 686
      Guanylate_kin; Guanylate kinase
      pfam10600
      Location:220 → 287
      PDZ_assoc; PDZ-associated domain of NMDA receptors
      pfam10608
      Location:7 → 39
      MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK

    10. XM_038514615.1 → XP_038370543.1  disks large homolog 4 isoform X7

      UniProtKB/TrEMBL
      A0A8C0MXR4, A0A8I3P9L3
      Conserved Domains (6) summary
      cd12030
      Location:408 → 473
      SH3_DLG4; Src Homology 3 domain of Disks Large homolog 4
      smart00228
      Location:288 → 372
      PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
      pfam00595
      Location:43 → 127
      PDZ; PDZ domain (Also known as DHR or GLGF)
      pfam00625
      Location:511 → 689
      Guanylate_kin; Guanylate kinase
      pfam10600
      Location:223 → 290
      PDZ_assoc; PDZ-associated domain of NMDA receptors
      pfam10608
      Location:7 → 42
      MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK

    11. XM_038514637.1 → XP_038370565.1  disks large homolog 4 isoform X9

      Conserved Domains (4) summary
      cd12030
      Location:145 → 210
      SH3_DLG4; Src Homology 3 domain of Disks Large homolog 4
      smart00228
      Location:25 → 109
      PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
      pfam00625
      Location:248 → 426
      Guanylate_kin; Guanylate kinase
      pfam10600
      Location:1 → 27
      PDZ_assoc; PDZ-associated domain of NMDA receptors

    RNA

    1. XR_005346672.1 RNA Sequence

    Nucleotide Protein
    Heading Accession and Version

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