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    CHRNA7 cholinergic receptor nicotinic alpha 7 subunit [ Canis lupus familiaris (dog) ]

    Gene ID: 488696, updated on 17-Aug-2024

    Summary

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    Official Symbol
    CHRNA7provided by VGNC
    Official Full Name
    cholinergic receptor nicotinic alpha 7 subunitprovided by VGNC
    Primary source
    VGNC:VGNC:109335
    See related
    Ensembl:ENSCAFG00845019829
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Orthologs
    human all
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    Genomic context

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    See CHRNA7 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 3 NC_051807.1 (37232973..37359572, complement)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 3 NC_006585.4 (39517659..39644156, complement)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 3 NC_049224.1 (37222873..37349426, complement)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 3 NC_049263.1 (36756424..36882829, complement)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 3 NC_049744.1 (37011929..37138401, complement)

    Chromosome 3 - NC_051807.1Genomic Context describing neighboring genes Neighboring gene S-formylglutathione hydrolase-like Neighboring gene U4 spliceosomal RNA Neighboring gene uncharacterized LOC119871186 Neighboring gene cleavage and polyadenylation specificity factor subunit 6 Neighboring gene OTU deubiquitinase 7A Neighboring gene pre-mRNA-splicing regulator WTAP-like

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables acetylcholine-gated monoatomic cation-selective channel activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables transmembrane signaling receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in chemical synaptic transmission IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in monoatomic ion transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in nervous system process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of membrane potential IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in neuron projection IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in postsynaptic membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in synapse IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    neuronal acetylcholine receptor subunit alpha-7; LOW QUALITY PROTEIN: neuronal acetylcholine receptor subunit alpha-7

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051807.1 Reference ROS_Cfam_1.0

      Range
      37232973..37359572 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038661111.1 → XP_038517039.1  neuronal acetylcholine receptor subunit alpha-7 isoform X2

      Conserved Domains (1) summary
      TIGR00860
      Location:21 → 427
      LIC; Cation transporter family protein

    2. XM_038661110.1 → XP_038517038.1  neuronal acetylcholine receptor subunit alpha-7 isoform X1

      UniProtKB/TrEMBL
      A0A8C0S3B3
      Related
      ENSCAFP00845027416.1, ENSCAFT00845035011.1
      Conserved Domains (1) summary
      TIGR00860
      Location:6 → 487
      LIC; Cation transporter family protein

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049263.1 Alternate UMICH_Zoey_3.1

      Range
      36756424..36882829 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038471672.1 → XP_038327600.1  LOW QUALITY PROTEIN: neuronal acetylcholine receptor subunit alpha-7 isoform X1

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049744.1 Alternate UNSW_CanFamBas_1.0

      Range
      37011929..37138401 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038596904.1 → XP_038452832.1  neuronal acetylcholine receptor subunit alpha-7 isoform X2

      Conserved Domains (1) summary
      TIGR00860
      Location:21 → 427
      LIC; Cation transporter family protein

    2. XM_038596903.1 → XP_038452831.1  neuronal acetylcholine receptor subunit alpha-7 isoform X1

      Conserved Domains (1) summary
      TIGR00860
      Location:6 → 487
      LIC; Cation transporter family protein

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049224.1 Alternate UU_Cfam_GSD_1.0

      Range
      37222873..37349426 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038532598.1 → XP_038388526.1  neuronal acetylcholine receptor subunit alpha-7 isoform X2

      Conserved Domains (1) summary
      TIGR00860
      Location:21 → 427
      LIC; Cation transporter family protein

    2. XM_038532597.1 → XP_038388525.1  neuronal acetylcholine receptor subunit alpha-7 isoform X1

      UniProtKB/TrEMBL
      A0A8C0S3B3

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006585.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      39517659..39644156 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_022416819.2 → XP_022272527.1  neuronal acetylcholine receptor subunit alpha-7 isoform X2

      Conserved Domains (1) summary
      TIGR00860
      Location:21 → 427
      LIC; Cation transporter family protein

    2. XM_545813.7 → XP_545813.4  neuronal acetylcholine receptor subunit alpha-7 isoform X1

      UniProtKB/TrEMBL
      A0A8C0S3B3, A0A8P0NCK2
      Conserved Domains (1) summary
      TIGR00860
      Location:6 → 487
      LIC; Cation transporter family protein
    Nucleotide Protein
    Heading Accession and Version

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