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    NEDD9 neural precursor cell expressed, developmentally down-regulated 9 [ Canis lupus familiaris (dog) ]

    Gene ID: 488220, updated on 17-Aug-2024

    Summary

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    Official Symbol
    NEDD9provided by VGNC
    Official Full Name
    neural precursor cell expressed, developmentally down-regulated 9provided by VGNC
    Primary source
    VGNC:VGNC:43722
    See related
    Ensembl:ENSCAFG00845020672
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Orthologs
    human mouse all
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    Genomic context

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    See NEDD9 in Genome Data Viewer
    Location:
    chromosome: 35
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 35 NC_051839.1 (10954569..11138759, complement)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 35 NC_006617.4 (10801380..10984979, complement)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 35 NC_049256.1 (12155116..12341102, complement)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 35 NC_049295.1 (10785077..10968606, complement)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 35 NC_049776.1 (10833555..11017186, complement)

    Chromosome 35 - NC_051839.1Genomic Context describing neighboring genes Neighboring gene ELOVL fatty acid elongase 2 Neighboring gene U6 snRNA-associated Sm-like protein LSm5 Neighboring gene small integral membrane protein 13 Neighboring gene uncharacterized LOC111094048 Neighboring gene uncharacterized LOC111094049 Neighboring gene uncharacterized LOC119867652 Neighboring gene uncharacterized LOC102152864

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cell migration IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cell surface receptor protein tyrosine kinase signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    enhancer of filamentation 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051839.1 Reference ROS_Cfam_1.0

      Range
      10954569..11138759 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038446380.1 → XP_038302308.1  enhancer of filamentation 1 isoform X2

      UniProtKB/Swiss-Prot
      A0A8I3P5P7, A0A8I3PDQ1, A0A8I3PEK1
      UniProtKB/TrEMBL
      A0A8C0ND23, A0A8C0R025
      Related
      ENSCAFP00845028565.1, ENSCAFT00845036501.1
      Conserved Domains (3) summary
      cd11550
      Location:401 → 562
      Serine_rich_NEDD9; Serine rich Four helix bundle domain of CAS (Crk-Associated Substrate) scaffolding protein, Neural precursor cell Expressed, Developmentally Down-regulated 9; a protein interaction module
      cd12002
      Location:7 → 63
      SH3_NEDD9; Src homology 3 domain of CAS (Crk-Associated Substrate) scaffolding protein family member, Neural precursor cell Expressed, Developmentally Down-regulated 9
      pfam12026
      Location:621 → 828
      DUF3513; Domain of unknown function (DUF3513)

    2. XM_038446379.1 → XP_038302307.1  enhancer of filamentation 1 isoform X1

      UniProtKB/TrEMBL
      A0A8C0ND23, A0A8C0R025, A0A8U4QSS3
      Related
      ENSCAFP00845028663.1, ENSCAFT00845036623.1
      Conserved Domains (3) summary
      cd11550
      Location:401 → 562
      Serine_rich_NEDD9; Serine rich Four helix bundle domain of CAS (Crk-Associated Substrate) scaffolding protein, Neural precursor cell Expressed, Developmentally Down-regulated 9; a protein interaction module
      cd12002
      Location:7 → 63
      SH3_NEDD9; Src homology 3 domain of CAS (Crk-Associated Substrate) scaffolding protein family member, Neural precursor cell Expressed, Developmentally Down-regulated 9
      pfam12026
      Location:621 → 828
      DUF3513; Domain of unknown function (DUF3513)

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049295.1 Alternate UMICH_Zoey_3.1

      Range
      10785077..10968606 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038520536.1 → XP_038376464.1  enhancer of filamentation 1 isoform X2

    2. XM_038520535.1 → XP_038376463.1  enhancer of filamentation 1 isoform X1

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049776.1 Alternate UNSW_CanFamBas_1.0

      Range
      10833555..11017186 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038648579.1 → XP_038504507.1  enhancer of filamentation 1 isoform X2

    2. XM_038648578.1 → XP_038504506.1  enhancer of filamentation 1 isoform X1

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049256.1 Alternate UU_Cfam_GSD_1.0

      Range
      12155116..12341102 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038584173.1 → XP_038440101.1  enhancer of filamentation 1 isoform X2

      UniProtKB/TrEMBL
      A0A8C0ND23, A0A8C0R025, A0A8P0NWP4

    2. XM_038584172.1 → XP_038440100.1  enhancer of filamentation 1 isoform X1

      UniProtKB/TrEMBL
      A0A8C0ND23, A0A8C0R025, A0A8P0NC68

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006617.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      10801380..10984979 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005640036.4 → XP_005640093.1  enhancer of filamentation 1 isoform X2

      UniProtKB/TrEMBL
      A0A8C0ND23, A0A8C0R025, A0A8P0NWP4
      Conserved Domains (3) summary
      cd11550
      Location:401 → 562
      Serine_rich_NEDD9; Serine rich Four helix bundle domain of CAS (Crk-Associated Substrate) scaffolding protein, Neural precursor cell Expressed, Developmentally Down-regulated 9; a protein interaction module
      cd12002
      Location:7 → 63
      SH3_NEDD9; Src homology 3 domain of CAS (Crk-Associated Substrate) scaffolding protein family member, Neural precursor cell Expressed, Developmentally Down-regulated 9
      pfam12026
      Location:621 → 828
      DUF3513; Domain of unknown function (DUF3513)

    2. XM_545342.7 → XP_545342.4  enhancer of filamentation 1 isoform X1

      UniProtKB/TrEMBL
      A0A8C0ND23, A0A8C0R025, A0A8P0NC68
      Conserved Domains (3) summary
      cd11550
      Location:401 → 562
      Serine_rich_NEDD9; Serine rich Four helix bundle domain of CAS (Crk-Associated Substrate) scaffolding protein, Neural precursor cell Expressed, Developmentally Down-regulated 9; a protein interaction module
      cd12002
      Location:7 → 63
      SH3_NEDD9; Src homology 3 domain of CAS (Crk-Associated Substrate) scaffolding protein family member, Neural precursor cell Expressed, Developmentally Down-regulated 9
      pfam12026
      Location:621 → 828
      DUF3513; Domain of unknown function (DUF3513)
    Nucleotide Protein
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