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    SERPINB1 serpin family B member 1 [ Canis lupus familiaris (dog) ]

    Gene ID: 488191, updated on 17-Aug-2024

    Summary

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    Official Symbol
    SERPINB1provided by VGNC
    Official Full Name
    serpin family B member 1provided by VGNC
    Primary source
    VGNC:VGNC:58332
    See related
    Ensembl:ENSCAFG00845017116
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Orthologs
    human all
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    Genomic context

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    See SERPINB1 in Genome Data Viewer
    Location:
    chromosome: 35
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 35 NC_051839.1 (3201536..3210182, complement)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 35 NC_006617.4 (3154221..3162902, complement)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 35 NC_049256.1 (4432360..4441097, complement)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 35 NC_049295.1 (3077400..3086040, complement)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 35 NC_049776.1 (3099914..3108812, complement)

    Chromosome 35 - NC_051839.1Genomic Context describing neighboring genes Neighboring gene myosin light chain kinase family member 4 Neighboring gene WRN helicase interacting protein 1 Neighboring gene uncharacterized LOC119867601 Neighboring gene uncharacterized LOC111094000 Neighboring gene uncharacterized LOC119867602 Neighboring gene serpin family B member 9 Neighboring gene uncharacterized LOC119867635

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables serine-type endopeptidase inhibitor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in negative regulation of endopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in extracellular space IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    leukocyte elastase inhibitor

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051839.1 Reference ROS_Cfam_1.0

      Range
      3201536..3210182 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038446224.1 → XP_038302152.1  leukocyte elastase inhibitor

      UniProtKB/TrEMBL
      A0A8C0MLU0, A0A8C0T1R4, A0A8I3P391
      Related
      ENSCAFP00845023788.1, ENSCAFT00845030333.1
      Conserved Domains (1) summary
      cd19560
      Location:1 → 378
      serpinB1_LEI; serpin family B member 1 (serpin B1), leukocyte elastase inhibitor (LEI)

    2. XM_038446225.1 → XP_038302153.1  leukocyte elastase inhibitor

      UniProtKB/TrEMBL
      A0A8C0MLU0, A0A8C0T1R4, A0A8I3P391
      Conserved Domains (1) summary
      cd19560
      Location:1 → 378
      serpinB1_LEI; serpin family B member 1 (serpin B1), leukocyte elastase inhibitor (LEI)

    3. XM_038446226.1 → XP_038302154.1  leukocyte elastase inhibitor

      UniProtKB/TrEMBL
      A0A8C0MLU0, A0A8C0T1R4, A0A8I3P391
      Conserved Domains (1) summary
      cd19560
      Location:1 → 378
      serpinB1_LEI; serpin family B member 1 (serpin B1), leukocyte elastase inhibitor (LEI)

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049295.1 Alternate UMICH_Zoey_3.1

      Range
      3077400..3086040 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038520399.1 → XP_038376327.1  leukocyte elastase inhibitor

    2. XM_038520400.1 → XP_038376328.1  leukocyte elastase inhibitor

    3. XM_038520401.1 → XP_038376329.1  leukocyte elastase inhibitor

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049776.1 Alternate UNSW_CanFamBas_1.0

      Range
      3099914..3108812 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038648434.1 → XP_038504362.1  leukocyte elastase inhibitor

    2. XM_038648435.1 → XP_038504363.1  leukocyte elastase inhibitor

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049256.1 Alternate UU_Cfam_GSD_1.0

      Range
      4432360..4441097 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038584019.1 → XP_038439947.1  leukocyte elastase inhibitor

      UniProtKB/TrEMBL
      A0A8C0MLU0, A0A8C0T1R4, A0A8I3P391
      Conserved Domains (1) summary
      cd19560
      Location:1 → 378
      serpinB1_LEI; serpin family B member 1 (serpin B1), leukocyte elastase inhibitor (LEI)

    2. XM_038584020.1 → XP_038439948.1  leukocyte elastase inhibitor

      UniProtKB/TrEMBL
      A0A8C0MLU0, A0A8C0T1R4, A0A8I3P391
      Conserved Domains (1) summary
      cd19560
      Location:1 → 378
      serpinB1_LEI; serpin family B member 1 (serpin B1), leukocyte elastase inhibitor (LEI)

    3. XM_038584021.1 → XP_038439949.1  leukocyte elastase inhibitor

      UniProtKB/TrEMBL
      A0A8C0MLU0, A0A8C0T1R4, A0A8I3P391
      Conserved Domains (1) summary
      cd19560
      Location:1 → 378
      serpinB1_LEI; serpin family B member 1 (serpin B1), leukocyte elastase inhibitor (LEI)

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006617.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      3154221..3162902 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038463111.1 → XP_038319039.1  leukocyte elastase inhibitor

      UniProtKB/TrEMBL
      A0A8C0MLU0, A0A8C0T1R4, A0A8I3P391
      Conserved Domains (1) summary
      cd19560
      Location:1 → 378
      serpinB1_LEI; serpin family B member 1 (serpin B1), leukocyte elastase inhibitor (LEI)

    2. XM_038463112.1 → XP_038319040.1  leukocyte elastase inhibitor

      UniProtKB/TrEMBL
      A0A8C0MLU0, A0A8C0T1R4, A0A8I3P391
      Conserved Domains (1) summary
      cd19560
      Location:1 → 378
      serpinB1_LEI; serpin family B member 1 (serpin B1), leukocyte elastase inhibitor (LEI)

    3. XM_038463113.1 → XP_038319041.1  leukocyte elastase inhibitor

      UniProtKB/TrEMBL
      A0A8C0MLU0, A0A8C0T1R4, A0A8I3P391
      Conserved Domains (1) summary
      cd19560
      Location:1 → 378
      serpinB1_LEI; serpin family B member 1 (serpin B1), leukocyte elastase inhibitor (LEI)
    Nucleotide Protein
    Heading Accession and Version

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