DYRK1A dual specificity tyrosine phosphorylation regulated kinase 1A [Canis lupus familiaris (dog)] - Gene

Summary

Official Symbol: DYRK1Aprovided by VGNC
Official Full Name: dual specificity tyrosine phosphorylation regulated kinase 1Aprovided by VGNC
Primary source: VGNC:VGNC:40155
See related: Ensembl:ENSCAFG00845028759
Gene type: protein coding
RefSeq status: MODEL
Organism: Canis lupus familiaris (sub-species: familiaris)
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 31

Exon count:: 13

Annotation release	Status	Assembly	Chr	Location
106	current	ROS_Cfam_1.0 (GCF_014441545.1)	31	NC_051835.1 (31812898..31959979)
106	current	Dog10K_Boxer_Tasha (GCF_000002285.5)	31	NC_006613.4 (31572154..31719378)
106	current	UU_Cfam_GSD_1.0 (GCF_011100685.1)	31	NC_049252.1 (32186102..32332696)
106	current	UMICH_Zoey_3.1 (GCF_005444595.1)	31	NC_049291.1 (31682502..31829001)
106	current	UNSW_CanFamBas_1.0 (GCF_013276365.1)	31	NC_049772.1 (31695751..31842602)

Chromosome 31 - NC_051835.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Pathways from PubChem

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General gene information

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Markers

DYRK1A__4795 (e-PCR)
- UniSTS:462887

D11Wox11 (e-PCR)
- UniSTS:518811

Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables ATP binding	IEA Inferred from Electronic Annotation more info	PubMed
enables protein serine/threonine kinase activity	IEA Inferred from Electronic Annotation more info	PubMed
enables protein serine/threonine/tyrosine kinase activity	IEA Inferred from Electronic Annotation more info	PubMed
enables transcription coactivator activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in peptidyl-serine phosphorylation	IEA Inferred from Electronic Annotation more info	PubMed
involved_in peptidyl-threonine phosphorylation	IEA Inferred from Electronic Annotation more info	PubMed
involved_in positive regulation of DNA-templated transcription	IEA Inferred from Electronic Annotation more info	PubMed
involved_in protein autophosphorylation	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in nucleus	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: dual specificity tyrosine-phosphorylation-regulated kinase 1A

XP_038299423.1

EC 2.7.1.-

EC 2.7.11.23

EC 2.7.12.1

XP_038299424.1

EC 2.7.1.-

EC 2.7.11.23

EC 2.7.12.1

XP_038299425.1

EC 2.7.1.-

EC 2.7.11.23

EC 2.7.12.1

XP_038317628.1

EC 2.7.1.-

EC 2.7.11.23

EC 2.7.12.1

XP_038317629.1

EC 2.7.1.-

EC 2.7.11.23

EC 2.7.12.1

XP_038317630.1

EC 2.7.1.-

EC 2.7.11.23

EC 2.7.12.1

XP_038373835.1

EC 2.7.1.-

EC 2.7.11.23

EC 2.7.12.1

XP_038373836.1

EC 2.7.1.-

EC 2.7.11.23

EC 2.7.12.1

XP_038373837.1

EC 2.7.1.-

EC 2.7.11.23

EC 2.7.12.1

XP_038437403.1

EC 2.7.1.-

EC 2.7.11.23

EC 2.7.12.1

XP_038437404.1

EC 2.7.1.-

EC 2.7.11.23

EC 2.7.12.1

XP_038437405.1

EC 2.7.1.-

EC 2.7.11.23

EC 2.7.12.1

XP_038501786.1

EC 2.7.1.-

EC 2.7.11.23

EC 2.7.12.1

XP_038501787.1

EC 2.7.1.-

EC 2.7.11.23

EC 2.7.12.1

XP_038501788.1

EC 2.7.1.-

EC 2.7.11.23

EC 2.7.12.1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

NC_051835.1 Reference ROS_Cfam_1.0

Range

31812898..31959979

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038443495.1 → XP_038299423.1 dual specificity tyrosine-phosphorylation-regulated kinase 1A isoform X1

UniProtKB/TrEMBL

A0A8C0LF11, A0A8C0PFN4, A0A8I3QQK0, A0A8P0TPS2

Conserved Domains (1) summary

cd14226
Location:148 → 484

PKc_DYRK1; Catalytic domain of the protein kinase, Dual-specificity tYrosine-phosphorylated and -Regulated Kinase 1
XM_038443496.1 → XP_038299424.1 dual specificity tyrosine-phosphorylation-regulated kinase 1A isoform X2

UniProtKB/TrEMBL

A0A8C0LF11, A0A8I3Q182, A0A8I3QQK0, A0A8P0NBW5, A0A8P0TPS2

Related

ENSCAFP00845039923.1, ENSCAFT00845050926.1

Conserved Domains (1) summary

cd14226
Location:139 → 475

PKc_DYRK1; Catalytic domain of the protein kinase, Dual-specificity tYrosine-phosphorylated and -Regulated Kinase 1
XM_038443497.1 → XP_038299425.1 dual specificity tyrosine-phosphorylation-regulated kinase 1A isoform X3

UniProtKB/TrEMBL

A0A8C0LF11, A0A8I3QQK0, A0A8P0TPS2

Related

ENSCAFP00845039970.1, ENSCAFT00845050986.1

Conserved Domains (1) summary

cd14226
Location:119 → 455

PKc_DYRK1; Catalytic domain of the protein kinase, Dual-specificity tYrosine-phosphorylated and -Regulated Kinase 1

Alternate UMICH_Zoey_3.1

Genomic

NC_049291.1 Alternate UMICH_Zoey_3.1

Range

31682502..31829001

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038517907.1 → XP_038373835.1 dual specificity tyrosine-phosphorylation-regulated kinase 1A isoform X1

Conserved Domains (1) summary

cd14226
Location:148 → 484

PKc_DYRK1; Catalytic domain of the protein kinase, Dual-specificity tYrosine-phosphorylated and -Regulated Kinase 1
XM_038517908.1 → XP_038373836.1 dual specificity tyrosine-phosphorylation-regulated kinase 1A isoform X2

Conserved Domains (1) summary

cd14226
Location:139 → 475

PKc_DYRK1; Catalytic domain of the protein kinase, Dual-specificity tYrosine-phosphorylated and -Regulated Kinase 1
XM_038517909.1 → XP_038373837.1 dual specificity tyrosine-phosphorylation-regulated kinase 1A isoform X3

Conserved Domains (1) summary

cd14226
Location:119 → 455

PKc_DYRK1; Catalytic domain of the protein kinase, Dual-specificity tYrosine-phosphorylated and -Regulated Kinase 1

Alternate UNSW_CanFamBas_1.0

Genomic

NC_049772.1 Alternate UNSW_CanFamBas_1.0

Range

31695751..31842602

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038645858.1 → XP_038501786.1 dual specificity tyrosine-phosphorylation-regulated kinase 1A isoform X1

Conserved Domains (1) summary

cd14226
Location:148 → 484

PKc_DYRK1; Catalytic domain of the protein kinase, Dual-specificity tYrosine-phosphorylated and -Regulated Kinase 1
XM_038645859.1 → XP_038501787.1 dual specificity tyrosine-phosphorylation-regulated kinase 1A isoform X2

Conserved Domains (1) summary

cd14226
Location:139 → 475

PKc_DYRK1; Catalytic domain of the protein kinase, Dual-specificity tYrosine-phosphorylated and -Regulated Kinase 1
XM_038645860.1 → XP_038501788.1 dual specificity tyrosine-phosphorylation-regulated kinase 1A isoform X3

Conserved Domains (1) summary

cd14226
Location:119 → 455

PKc_DYRK1; Catalytic domain of the protein kinase, Dual-specificity tYrosine-phosphorylated and -Regulated Kinase 1

Alternate UU_Cfam_GSD_1.0

Genomic

NC_049252.1 Alternate UU_Cfam_GSD_1.0

Range

32186102..32332696

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038581475.1 → XP_038437403.1 dual specificity tyrosine-phosphorylation-regulated kinase 1A isoform X1

UniProtKB/TrEMBL

A0A8C0LF11, A0A8C0PFN4, A0A8I3QQK0, A0A8P0TPS2

Conserved Domains (1) summary

cd14226
Location:148 → 484

PKc_DYRK1; Catalytic domain of the protein kinase, Dual-specificity tYrosine-phosphorylated and -Regulated Kinase 1
XM_038581476.1 → XP_038437404.1 dual specificity tyrosine-phosphorylation-regulated kinase 1A isoform X2

UniProtKB/TrEMBL

A0A8C0LF11, A0A8I3Q182, A0A8I3QQK0, A0A8P0NBW5, A0A8P0TPS2

Conserved Domains (1) summary

cd14226
Location:139 → 475

PKc_DYRK1; Catalytic domain of the protein kinase, Dual-specificity tYrosine-phosphorylated and -Regulated Kinase 1
XM_038581477.1 → XP_038437405.1 dual specificity tyrosine-phosphorylation-regulated kinase 1A isoform X3

UniProtKB/TrEMBL

A0A8C0LF11, A0A8I3QQK0, A0A8P0TPS2

Conserved Domains (1) summary

cd14226
Location:119 → 455

PKc_DYRK1; Catalytic domain of the protein kinase, Dual-specificity tYrosine-phosphorylated and -Regulated Kinase 1

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

NC_006613.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

Range

31572154..31719378

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038461700.1 → XP_038317628.1 dual specificity tyrosine-phosphorylation-regulated kinase 1A isoform X1

UniProtKB/TrEMBL

A0A8C0LF11, A0A8C0PFN4, A0A8I3QQK0, A0A8P0TPS2

Conserved Domains (1) summary

cd14226
Location:148 → 484

PKc_DYRK1; Catalytic domain of the protein kinase, Dual-specificity tYrosine-phosphorylated and -Regulated Kinase 1
XM_038461701.1 → XP_038317629.1 dual specificity tyrosine-phosphorylation-regulated kinase 1A isoform X2

UniProtKB/TrEMBL

A0A8C0LF11, A0A8I3Q182, A0A8I3QQK0, A0A8P0NBW5, A0A8P0TPS2

Conserved Domains (1) summary

cd14226
Location:139 → 475

PKc_DYRK1; Catalytic domain of the protein kinase, Dual-specificity tYrosine-phosphorylated and -Regulated Kinase 1
XM_038461702.1 → XP_038317630.1 dual specificity tyrosine-phosphorylation-regulated kinase 1A isoform X3

UniProtKB/TrEMBL

A0A8C0LF11, A0A8I3QQK0, A0A8P0TPS2

Conserved Domains (1) summary

cd14226
Location:119 → 455

PKc_DYRK1; Catalytic domain of the protein kinase, Dual-specificity tYrosine-phosphorylated and -Regulated Kinase 1