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    CSK C-terminal Src kinase [ Canis lupus familiaris (dog) ]

    Gene ID: 487649, updated on 17-Aug-2024

    Summary

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    Official Symbol
    CSKprovided by VGNC
    Official Full Name
    C-terminal Src kinaseprovided by VGNC
    Primary source
    VGNC:VGNC:39661
    See related
    Ensembl:ENSCAFG00845017685
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Orthologs
    human mouse all
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    Genomic context

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    See CSK in Genome Data Viewer
    Location:
    chromosome: 30
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 30 NC_051834.1 (38056541..38074206)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 30 NC_006612.4 (37784125..37802413)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 30 NC_049251.1 (38291119..38309429)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 30 NC_049290.1 (38009325..38027610)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 30 NC_049771.1 (38055644..38073934)

    Chromosome 30 - NC_051834.1Genomic Context describing neighboring genes Neighboring gene cytochrome P450 family 1 subfamily A member 1 Neighboring gene cytochrome P450 family 1 subfamily A member 2 Neighboring gene lectin, mannose binding 1 like Neighboring gene complexin 3

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein tyrosine kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in adherens junction organization IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of Fc receptor mediated stimulatory signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    tyrosine-protein kinase CSK
    Names
    CSK, non-receptor tyrosine kinase
    c-src tyrosine kinase
    XP_005638681.1
    XP_005638682.1
    XP_022268391.1
    XP_038298884.1
    XP_038298885.1
    XP_038298886.1
    XP_038373330.1
    XP_038373331.1
    XP_038373332.1
    XP_038373333.1
    XP_038436926.1
    XP_038436927.1
    XP_038436928.1
    XP_038436929.1
    XP_038501292.1
    XP_038501293.1
    XP_038501294.1
    XP_038501295.1
    XP_544774.4

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051834.1 Reference ROS_Cfam_1.0

      Range
      38056541..38074206
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038442956.1 → XP_038298884.1  tyrosine-protein kinase CSK

      UniProtKB/TrEMBL
      A0A8I3P4Z0
      Related
      ENSCAFP00845024518.1, ENSCAFT00845031318.1
      Conserved Domains (3) summary
      cd05082
      Location:193 → 448
      PTKc_Csk; Catalytic domain of the Protein Tyrosine Kinase, C-terminal Src kinase
      cd09937
      Location:78 → 180
      SH2_csk_like; Src homology 2 (SH2) domain found in Carboxyl-Terminal Src Kinase (Csk)
      cd11769
      Location:11 → 67
      SH3_CSK; Src Homology 3 domain of C-terminal Src kinase

    2. XM_038442957.1 → XP_038298885.1  tyrosine-protein kinase CSK

      UniProtKB/TrEMBL
      A0A8I3P4Z0
      Conserved Domains (3) summary
      cd05082
      Location:193 → 448
      PTKc_Csk; Catalytic domain of the Protein Tyrosine Kinase, C-terminal Src kinase
      cd09937
      Location:78 → 180
      SH2_csk_like; Src homology 2 (SH2) domain found in Carboxyl-Terminal Src Kinase (Csk)
      cd11769
      Location:11 → 67
      SH3_CSK; Src Homology 3 domain of C-terminal Src kinase

    3. XM_038442958.1 → XP_038298886.1  tyrosine-protein kinase CSK

      UniProtKB/TrEMBL
      A0A8I3P4Z0
      Conserved Domains (3) summary
      cd05082
      Location:193 → 448
      PTKc_Csk; Catalytic domain of the Protein Tyrosine Kinase, C-terminal Src kinase
      cd09937
      Location:78 → 180
      SH2_csk_like; Src homology 2 (SH2) domain found in Carboxyl-Terminal Src Kinase (Csk)
      cd11769
      Location:11 → 67
      SH3_CSK; Src Homology 3 domain of C-terminal Src kinase

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049290.1 Alternate UMICH_Zoey_3.1

      Range
      38009325..38027610
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038517402.1 → XP_038373330.1  tyrosine-protein kinase CSK

      Conserved Domains (3) summary
      cd05082
      Location:188 → 443
      PTKc_Csk; Catalytic domain of the Protein Tyrosine Kinase, C-terminal Src kinase
      cd09937
      Location:78 → 175
      SH2_csk_like; Src homology 2 (SH2) domain found in Carboxyl-Terminal Src Kinase (Csk)
      cd11769
      Location:11 → 67
      SH3_CSK; Src Homology 3 domain of C-terminal Src kinase

    2. XM_038517403.1 → XP_038373331.1  tyrosine-protein kinase CSK

      Conserved Domains (3) summary
      cd05082
      Location:188 → 443
      PTKc_Csk; Catalytic domain of the Protein Tyrosine Kinase, C-terminal Src kinase
      cd09937
      Location:78 → 175
      SH2_csk_like; Src homology 2 (SH2) domain found in Carboxyl-Terminal Src Kinase (Csk)
      cd11769
      Location:11 → 67
      SH3_CSK; Src Homology 3 domain of C-terminal Src kinase

    3. XM_038517404.1 → XP_038373332.1  tyrosine-protein kinase CSK

      Conserved Domains (3) summary
      cd05082
      Location:188 → 443
      PTKc_Csk; Catalytic domain of the Protein Tyrosine Kinase, C-terminal Src kinase
      cd09937
      Location:78 → 175
      SH2_csk_like; Src homology 2 (SH2) domain found in Carboxyl-Terminal Src Kinase (Csk)
      cd11769
      Location:11 → 67
      SH3_CSK; Src Homology 3 domain of C-terminal Src kinase

    4. XM_038517405.1 → XP_038373333.1  tyrosine-protein kinase CSK

      Conserved Domains (3) summary
      cd05082
      Location:188 → 443
      PTKc_Csk; Catalytic domain of the Protein Tyrosine Kinase, C-terminal Src kinase
      cd09937
      Location:78 → 175
      SH2_csk_like; Src homology 2 (SH2) domain found in Carboxyl-Terminal Src Kinase (Csk)
      cd11769
      Location:11 → 67
      SH3_CSK; Src Homology 3 domain of C-terminal Src kinase

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049771.1 Alternate UNSW_CanFamBas_1.0

      Range
      38055644..38073934
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038645364.1 → XP_038501292.1  tyrosine-protein kinase CSK

      Conserved Domains (3) summary
      cd05082
      Location:188 → 443
      PTKc_Csk; Catalytic domain of the Protein Tyrosine Kinase, C-terminal Src kinase
      cd09937
      Location:78 → 175
      SH2_csk_like; Src homology 2 (SH2) domain found in Carboxyl-Terminal Src Kinase (Csk)
      cd11769
      Location:11 → 67
      SH3_CSK; Src Homology 3 domain of C-terminal Src kinase

    2. XM_038645365.1 → XP_038501293.1  tyrosine-protein kinase CSK

      Conserved Domains (3) summary
      cd05082
      Location:188 → 443
      PTKc_Csk; Catalytic domain of the Protein Tyrosine Kinase, C-terminal Src kinase
      cd09937
      Location:78 → 175
      SH2_csk_like; Src homology 2 (SH2) domain found in Carboxyl-Terminal Src Kinase (Csk)
      cd11769
      Location:11 → 67
      SH3_CSK; Src Homology 3 domain of C-terminal Src kinase

    3. XM_038645366.1 → XP_038501294.1  tyrosine-protein kinase CSK

      Conserved Domains (3) summary
      cd05082
      Location:188 → 443
      PTKc_Csk; Catalytic domain of the Protein Tyrosine Kinase, C-terminal Src kinase
      cd09937
      Location:78 → 175
      SH2_csk_like; Src homology 2 (SH2) domain found in Carboxyl-Terminal Src Kinase (Csk)
      cd11769
      Location:11 → 67
      SH3_CSK; Src Homology 3 domain of C-terminal Src kinase

    4. XM_038645367.1 → XP_038501295.1  tyrosine-protein kinase CSK

      Conserved Domains (3) summary
      cd05082
      Location:188 → 443
      PTKc_Csk; Catalytic domain of the Protein Tyrosine Kinase, C-terminal Src kinase
      cd09937
      Location:78 → 175
      SH2_csk_like; Src homology 2 (SH2) domain found in Carboxyl-Terminal Src Kinase (Csk)
      cd11769
      Location:11 → 67
      SH3_CSK; Src Homology 3 domain of C-terminal Src kinase

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049251.1 Alternate UU_Cfam_GSD_1.0

      Range
      38291119..38309429
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038580998.1 → XP_038436926.1  tyrosine-protein kinase CSK

      UniProtKB/TrEMBL
      A0A8C0JTF8, A0A8C0RH82, A0A8P0NJE6
      Conserved Domains (3) summary
      cd05082
      Location:188 → 443
      PTKc_Csk; Catalytic domain of the Protein Tyrosine Kinase, C-terminal Src kinase
      cd09937
      Location:78 → 175
      SH2_csk_like; Src homology 2 (SH2) domain found in Carboxyl-Terminal Src Kinase (Csk)
      cd11769
      Location:11 → 67
      SH3_CSK; Src Homology 3 domain of C-terminal Src kinase

    2. XM_038580999.1 → XP_038436927.1  tyrosine-protein kinase CSK

      UniProtKB/TrEMBL
      A0A8C0JTF8, A0A8C0RH82, A0A8P0NJE6
      Conserved Domains (3) summary
      cd05082
      Location:188 → 443
      PTKc_Csk; Catalytic domain of the Protein Tyrosine Kinase, C-terminal Src kinase
      cd09937
      Location:78 → 175
      SH2_csk_like; Src homology 2 (SH2) domain found in Carboxyl-Terminal Src Kinase (Csk)
      cd11769
      Location:11 → 67
      SH3_CSK; Src Homology 3 domain of C-terminal Src kinase

    3. XM_038581000.1 → XP_038436928.1  tyrosine-protein kinase CSK

      UniProtKB/TrEMBL
      A0A8C0JTF8, A0A8C0RH82, A0A8P0NJE6
      Conserved Domains (3) summary
      cd05082
      Location:188 → 443
      PTKc_Csk; Catalytic domain of the Protein Tyrosine Kinase, C-terminal Src kinase
      cd09937
      Location:78 → 175
      SH2_csk_like; Src homology 2 (SH2) domain found in Carboxyl-Terminal Src Kinase (Csk)
      cd11769
      Location:11 → 67
      SH3_CSK; Src Homology 3 domain of C-terminal Src kinase

    4. XM_038581001.1 → XP_038436929.1  tyrosine-protein kinase CSK

      UniProtKB/TrEMBL
      A0A8C0JTF8, A0A8C0RH82, A0A8P0NJE6
      Conserved Domains (3) summary
      cd05082
      Location:188 → 443
      PTKc_Csk; Catalytic domain of the Protein Tyrosine Kinase, C-terminal Src kinase
      cd09937
      Location:78 → 175
      SH2_csk_like; Src homology 2 (SH2) domain found in Carboxyl-Terminal Src Kinase (Csk)
      cd11769
      Location:11 → 67
      SH3_CSK; Src Homology 3 domain of C-terminal Src kinase

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006612.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      37784125..37802413
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_544774.7 → XP_544774.4  tyrosine-protein kinase CSK

      See identical proteins and their annotated locations for XP_544774.4

      UniProtKB/TrEMBL
      A0A8C0JTF8, A0A8C0RH82, A0A8P0NJE6
      Conserved Domains (3) summary
      cd05082
      Location:188 → 443
      PTKc_Csk; Catalytic domain of the Protein Tyrosine Kinase, C-terminal Src kinase
      cd09937
      Location:78 → 175
      SH2_csk_like; Src homology 2 (SH2) domain found in Carboxyl-Terminal Src Kinase (Csk)
      cd11769
      Location:11 → 67
      SH3_CSK; Src Homology 3 domain of C-terminal Src kinase

    2. XM_005638624.4 → XP_005638681.1  tyrosine-protein kinase CSK

      See identical proteins and their annotated locations for XP_005638681.1

      UniProtKB/TrEMBL
      A0A8C0JTF8, A0A8C0RH82, A0A8P0NJE6
      Conserved Domains (3) summary
      cd05082
      Location:188 → 443
      PTKc_Csk; Catalytic domain of the Protein Tyrosine Kinase, C-terminal Src kinase
      cd09937
      Location:78 → 175
      SH2_csk_like; Src homology 2 (SH2) domain found in Carboxyl-Terminal Src Kinase (Csk)
      cd11769
      Location:11 → 67
      SH3_CSK; Src Homology 3 domain of C-terminal Src kinase

    3. XM_005638625.4 → XP_005638682.1  tyrosine-protein kinase CSK

      See identical proteins and their annotated locations for XP_005638682.1

      UniProtKB/TrEMBL
      A0A8C0JTF8, A0A8C0RH82, A0A8P0NJE6
      Conserved Domains (3) summary
      cd05082
      Location:188 → 443
      PTKc_Csk; Catalytic domain of the Protein Tyrosine Kinase, C-terminal Src kinase
      cd09937
      Location:78 → 175
      SH2_csk_like; Src homology 2 (SH2) domain found in Carboxyl-Terminal Src Kinase (Csk)
      cd11769
      Location:11 → 67
      SH3_CSK; Src Homology 3 domain of C-terminal Src kinase

    4. XM_022412683.2 → XP_022268391.1  tyrosine-protein kinase CSK

      UniProtKB/TrEMBL
      A0A8C0JTF8, A0A8C0RH82, A0A8P0NJE6
      Conserved Domains (3) summary
      cd05082
      Location:188 → 443
      PTKc_Csk; Catalytic domain of the Protein Tyrosine Kinase, C-terminal Src kinase
      cd09937
      Location:78 → 175
      SH2_csk_like; Src homology 2 (SH2) domain found in Carboxyl-Terminal Src Kinase (Csk)
      cd11769
      Location:11 → 67
      SH3_CSK; Src Homology 3 domain of C-terminal Src kinase
    Nucleotide Protein
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