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    MAP3K8 mitogen-activated protein kinase kinase kinase 8 [ Canis lupus familiaris (dog) ]

    Gene ID: 487085, updated on 17-Aug-2024

    Summary

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    Official Symbol
    MAP3K8provided by VGNC
    Official Full Name
    mitogen-activated protein kinase kinase kinase 8provided by VGNC
    Primary source
    VGNC:VGNC:42979
    See related
    Ensembl:ENSCAFG00845011569
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Orthologs
    human mouse all
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    Genomic context

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    See MAP3K8 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 2 NC_051806.1 (14958609..14981846)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 2 NC_006584.4 (14213953..14236910)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 2 NC_049223.1 (14562884..14585927)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 2 NC_049262.1 (14403368..14426326)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 2 NC_049743.1 (14289689..14313028)

    Chromosome 2 - NC_051806.1Genomic Context describing neighboring genes Neighboring gene mitochondrial poly(A) polymerase Neighboring gene uncharacterized LOC119870122 Neighboring gene 60S ribosomal protein L23a-like Neighboring gene lysozyme-like protein 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    mitogen-activated protein kinase kinase kinase 8
    XP_005617113.1
    XP_005617114.1
    XP_038312444.1
    XP_038312460.1
    XP_038325133.1
    XP_038325134.1
    XP_038325135.1
    XP_038325136.1
    XP_038325137.1
    XP_038385844.1
    XP_038385845.1
    XP_038385846.1
    XP_038385847.1
    XP_038385848.1
    XP_038385849.1
    XP_038450113.1
    XP_038450114.1
    XP_038450115.1
    XP_038450116.1
    XP_038450117.1
    XP_038450118.1
    XP_038514169.1
    XP_038514170.1
    XP_038514171.1
    XP_038514172.1
    XP_038514173.1
    XP_038514174.1
    XP_544213.3

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051806.1 Reference ROS_Cfam_1.0

      Range
      14958609..14981846
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038658243.1 → XP_038514171.1  mitogen-activated protein kinase kinase kinase 8

      UniProtKB/TrEMBL
      A0A8C0LWP0, A0A8C0PSJ6, A0A8I3N8I4
      Conserved Domains (1) summary
      cd13995
      Location:133 → 388
      STKc_MAP3K8; Catalytic domain of the Serine/Threonine kinase, Mitogen-Activated Protein Kinase (MAPK) Kinase Kinase 8

    2. XM_038658244.1 → XP_038514172.1  mitogen-activated protein kinase kinase kinase 8

      UniProtKB/TrEMBL
      A0A8C0LWP0, A0A8C0PSJ6, A0A8I3N8I4
      Conserved Domains (1) summary
      cd13995
      Location:133 → 388
      STKc_MAP3K8; Catalytic domain of the Serine/Threonine kinase, Mitogen-Activated Protein Kinase (MAPK) Kinase Kinase 8

    3. XM_038658241.1 → XP_038514169.1  mitogen-activated protein kinase kinase kinase 8

      UniProtKB/TrEMBL
      A0A8C0LWP0, A0A8C0PSJ6, A0A8I3N8I4
      Conserved Domains (1) summary
      cd13995
      Location:133 → 388
      STKc_MAP3K8; Catalytic domain of the Serine/Threonine kinase, Mitogen-Activated Protein Kinase (MAPK) Kinase Kinase 8

    4. XM_038658245.1 → XP_038514173.1  mitogen-activated protein kinase kinase kinase 8

      UniProtKB/TrEMBL
      A0A8C0LWP0, A0A8C0PSJ6, A0A8I3N8I4
      Conserved Domains (1) summary
      cd13995
      Location:133 → 388
      STKc_MAP3K8; Catalytic domain of the Serine/Threonine kinase, Mitogen-Activated Protein Kinase (MAPK) Kinase Kinase 8

    5. XM_038658242.1 → XP_038514170.1  mitogen-activated protein kinase kinase kinase 8

      UniProtKB/TrEMBL
      A0A8C0LWP0, A0A8C0PSJ6, A0A8I3N8I4
      Related
      ENSCAFP00845016086.1, ENSCAFT00845020516.1
      Conserved Domains (1) summary
      cd13995
      Location:133 → 388
      STKc_MAP3K8; Catalytic domain of the Serine/Threonine kinase, Mitogen-Activated Protein Kinase (MAPK) Kinase Kinase 8

    6. XM_038658246.1 → XP_038514174.1  mitogen-activated protein kinase kinase kinase 8

      UniProtKB/TrEMBL
      A0A8C0LWP0, A0A8C0PSJ6, A0A8I3N8I4
      Conserved Domains (1) summary
      cd13995
      Location:133 → 388
      STKc_MAP3K8; Catalytic domain of the Serine/Threonine kinase, Mitogen-Activated Protein Kinase (MAPK) Kinase Kinase 8

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049262.1 Alternate UMICH_Zoey_3.1

      Range
      14403368..14426326
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038469206.1 → XP_038325134.1  mitogen-activated protein kinase kinase kinase 8

      Conserved Domains (1) summary
      cd13995
      Location:133 → 388
      STKc_MAP3K8; Catalytic domain of the Serine/Threonine kinase, Mitogen-Activated Protein Kinase (MAPK) Kinase Kinase 8

    2. XM_038469207.1 → XP_038325135.1  mitogen-activated protein kinase kinase kinase 8

      Conserved Domains (1) summary
      cd13995
      Location:133 → 388
      STKc_MAP3K8; Catalytic domain of the Serine/Threonine kinase, Mitogen-Activated Protein Kinase (MAPK) Kinase Kinase 8

    3. XM_038469205.1 → XP_038325133.1  mitogen-activated protein kinase kinase kinase 8

      Conserved Domains (1) summary
      cd13995
      Location:133 → 388
      STKc_MAP3K8; Catalytic domain of the Serine/Threonine kinase, Mitogen-Activated Protein Kinase (MAPK) Kinase Kinase 8

    4. XM_038469208.1 → XP_038325136.1  mitogen-activated protein kinase kinase kinase 8

      Conserved Domains (1) summary
      cd13995
      Location:133 → 388
      STKc_MAP3K8; Catalytic domain of the Serine/Threonine kinase, Mitogen-Activated Protein Kinase (MAPK) Kinase Kinase 8

    5. XM_038469209.1 → XP_038325137.1  mitogen-activated protein kinase kinase kinase 8

      Conserved Domains (1) summary
      cd13995
      Location:133 → 388
      STKc_MAP3K8; Catalytic domain of the Serine/Threonine kinase, Mitogen-Activated Protein Kinase (MAPK) Kinase Kinase 8

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049743.1 Alternate UNSW_CanFamBas_1.0

      Range
      14289689..14313028
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038594187.1 → XP_038450115.1  mitogen-activated protein kinase kinase kinase 8

      Conserved Domains (1) summary
      cd13995
      Location:133 → 388
      STKc_MAP3K8; Catalytic domain of the Serine/Threonine kinase, Mitogen-Activated Protein Kinase (MAPK) Kinase Kinase 8

    2. XM_038594188.1 → XP_038450116.1  mitogen-activated protein kinase kinase kinase 8

      Conserved Domains (1) summary
      cd13995
      Location:133 → 388
      STKc_MAP3K8; Catalytic domain of the Serine/Threonine kinase, Mitogen-Activated Protein Kinase (MAPK) Kinase Kinase 8

    3. XM_038594185.1 → XP_038450113.1  mitogen-activated protein kinase kinase kinase 8

      Conserved Domains (1) summary
      cd13995
      Location:133 → 388
      STKc_MAP3K8; Catalytic domain of the Serine/Threonine kinase, Mitogen-Activated Protein Kinase (MAPK) Kinase Kinase 8

    4. XM_038594189.1 → XP_038450117.1  mitogen-activated protein kinase kinase kinase 8

      Conserved Domains (1) summary
      cd13995
      Location:133 → 388
      STKc_MAP3K8; Catalytic domain of the Serine/Threonine kinase, Mitogen-Activated Protein Kinase (MAPK) Kinase Kinase 8

    5. XM_038594186.1 → XP_038450114.1  mitogen-activated protein kinase kinase kinase 8

      Conserved Domains (1) summary
      cd13995
      Location:133 → 388
      STKc_MAP3K8; Catalytic domain of the Serine/Threonine kinase, Mitogen-Activated Protein Kinase (MAPK) Kinase Kinase 8

    6. XM_038594190.1 → XP_038450118.1  mitogen-activated protein kinase kinase kinase 8

      Conserved Domains (1) summary
      cd13995
      Location:133 → 388
      STKc_MAP3K8; Catalytic domain of the Serine/Threonine kinase, Mitogen-Activated Protein Kinase (MAPK) Kinase Kinase 8

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049223.1 Alternate UU_Cfam_GSD_1.0

      Range
      14562884..14585927
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038529918.1 → XP_038385846.1  mitogen-activated protein kinase kinase kinase 8

      UniProtKB/TrEMBL
      A0A8C0LWP0, A0A8C0PSJ6, A0A8I3N8I4
      Conserved Domains (1) summary
      cd13995
      Location:133 → 388
      STKc_MAP3K8; Catalytic domain of the Serine/Threonine kinase, Mitogen-Activated Protein Kinase (MAPK) Kinase Kinase 8

    2. XM_038529919.1 → XP_038385847.1  mitogen-activated protein kinase kinase kinase 8

      UniProtKB/TrEMBL
      A0A8C0LWP0, A0A8C0PSJ6, A0A8I3N8I4
      Conserved Domains (1) summary
      cd13995
      Location:133 → 388
      STKc_MAP3K8; Catalytic domain of the Serine/Threonine kinase, Mitogen-Activated Protein Kinase (MAPK) Kinase Kinase 8

    3. XM_038529916.1 → XP_038385844.1  mitogen-activated protein kinase kinase kinase 8

      UniProtKB/TrEMBL
      A0A8C0LWP0, A0A8C0PSJ6, A0A8I3N8I4
      Conserved Domains (1) summary
      cd13995
      Location:133 → 388
      STKc_MAP3K8; Catalytic domain of the Serine/Threonine kinase, Mitogen-Activated Protein Kinase (MAPK) Kinase Kinase 8

    4. XM_038529920.1 → XP_038385848.1  mitogen-activated protein kinase kinase kinase 8

      UniProtKB/TrEMBL
      A0A8C0LWP0, A0A8C0PSJ6, A0A8I3N8I4
      Conserved Domains (1) summary
      cd13995
      Location:133 → 388
      STKc_MAP3K8; Catalytic domain of the Serine/Threonine kinase, Mitogen-Activated Protein Kinase (MAPK) Kinase Kinase 8

    5. XM_038529917.1 → XP_038385845.1  mitogen-activated protein kinase kinase kinase 8

      UniProtKB/TrEMBL
      A0A8C0LWP0, A0A8C0PSJ6, A0A8I3N8I4
      Conserved Domains (1) summary
      cd13995
      Location:133 → 388
      STKc_MAP3K8; Catalytic domain of the Serine/Threonine kinase, Mitogen-Activated Protein Kinase (MAPK) Kinase Kinase 8

    6. XM_038529921.1 → XP_038385849.1  mitogen-activated protein kinase kinase kinase 8

      UniProtKB/TrEMBL
      A0A8C0LWP0, A0A8C0PSJ6, A0A8I3N8I4
      Conserved Domains (1) summary
      cd13995
      Location:133 → 388
      STKc_MAP3K8; Catalytic domain of the Serine/Threonine kinase, Mitogen-Activated Protein Kinase (MAPK) Kinase Kinase 8

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006584.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      14213953..14236910
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038456516.1 → XP_038312444.1  mitogen-activated protein kinase kinase kinase 8

      UniProtKB/TrEMBL
      A0A8C0LWP0, A0A8C0PSJ6, A0A8I3N8I4
      Conserved Domains (1) summary
      cd13995
      Location:133 → 388
      STKc_MAP3K8; Catalytic domain of the Serine/Threonine kinase, Mitogen-Activated Protein Kinase (MAPK) Kinase Kinase 8

    2. XM_005617057.4 → XP_005617114.1  mitogen-activated protein kinase kinase kinase 8

      See identical proteins and their annotated locations for XP_005617114.1

      UniProtKB/TrEMBL
      A0A8C0LWP0, A0A8C0PSJ6, A0A8I3N8I4
      Conserved Domains (1) summary
      cd13995
      Location:133 → 388
      STKc_MAP3K8; Catalytic domain of the Serine/Threonine kinase, Mitogen-Activated Protein Kinase (MAPK) Kinase Kinase 8

    3. XM_005617056.4 → XP_005617113.1  mitogen-activated protein kinase kinase kinase 8

      See identical proteins and their annotated locations for XP_005617113.1

      UniProtKB/TrEMBL
      A0A8C0LWP0, A0A8C0PSJ6, A0A8I3N8I4
      Conserved Domains (1) summary
      cd13995
      Location:133 → 388
      STKc_MAP3K8; Catalytic domain of the Serine/Threonine kinase, Mitogen-Activated Protein Kinase (MAPK) Kinase Kinase 8

    4. XM_544213.7 → XP_544213.3  mitogen-activated protein kinase kinase kinase 8

      See identical proteins and their annotated locations for XP_544213.3

      UniProtKB/TrEMBL
      A0A8C0LWP0, A0A8C0PSJ6, A0A8I3N8I4
      Conserved Domains (1) summary
      cd13995
      Location:133 → 388
      STKc_MAP3K8; Catalytic domain of the Serine/Threonine kinase, Mitogen-Activated Protein Kinase (MAPK) Kinase Kinase 8

    5. XM_038456532.1 → XP_038312460.1  mitogen-activated protein kinase kinase kinase 8

      UniProtKB/TrEMBL
      A0A8C0LWP0, A0A8C0PSJ6, A0A8I3N8I4
      Conserved Domains (1) summary
      cd13995
      Location:133 → 388
      STKc_MAP3K8; Catalytic domain of the Serine/Threonine kinase, Mitogen-Activated Protein Kinase (MAPK) Kinase Kinase 8
    Nucleotide Protein
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