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    RACGAP1 Rac GTPase activating protein 1 [ Canis lupus familiaris (dog) ]

    Gene ID: 486549, updated on 17-Aug-2024

    Summary

    Official Symbol
    RACGAP1provided by VGNC
    Official Full Name
    Rac GTPase activating protein 1provided by VGNC
    Primary source
    VGNC:VGNC:45308
    See related
    Ensembl:ENSCAFG00845017966
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See RACGAP1 in Genome Data Viewer
    Location:
    chromosome: 27
    Exon count:
    18
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 27 NC_051831.1 (4737980..4766051)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 27 NC_006609.4 (41541242..41569279, complement)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 27 NC_049248.1 (41935897..41964171, complement)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 27 NC_049287.1 (4702991..4731034)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 27 NC_049768.1 (4692808..4720859)

    Chromosome 27 - NC_051831.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC119866368 Neighboring gene SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1 Neighboring gene acid sensing ion channel subunit 1 Neighboring gene uncharacterized LOC111092823 Neighboring gene aquaporin 6 Neighboring gene aquaporin 5

    Genomic regions, transcripts, and products

    Pathways from PubChem

    General protein information

    Preferred Names
    rac GTPase-activating protein 1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051831.1 Reference ROS_Cfam_1.0

      Range
      4737980..4766051
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038438224.1XP_038294152.1  rac GTPase-activating protein 1 isoform X1

      UniProtKB/TrEMBL
      A0A8C0KNK3, A0A8C0KNV2, A0A8I3PA63, A0A8P0SDH2
      Conserved Domains (3) summary
      cd04382
      Location:346539
      RhoGAP_MgcRacGAP; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in MgcRacGAP proteins. MgcRacGAP plays an important dual role in cytokinesis: i) it is part of centralspindlin-complex, together with the mitotic kinesin MKLP1, which is ...
      TIGR02168
      Location:13105
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      cd20821
      Location:285338
      C1_MgcRacGAP; protein kinase C conserved region 1 (C1 domain) found in male germ cell RacGap (MgcRacGAP) and similar proteins
    2. XM_038438228.1XP_038294156.1  rac GTPase-activating protein 1 isoform X1

      UniProtKB/TrEMBL
      A0A8C0KNK3, A0A8C0KNV2, A0A8I3PA63, A0A8P0SDH2
      Conserved Domains (3) summary
      cd04382
      Location:346539
      RhoGAP_MgcRacGAP; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in MgcRacGAP proteins. MgcRacGAP plays an important dual role in cytokinesis: i) it is part of centralspindlin-complex, together with the mitotic kinesin MKLP1, which is ...
      TIGR02168
      Location:13105
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      cd20821
      Location:285338
      C1_MgcRacGAP; protein kinase C conserved region 1 (C1 domain) found in male germ cell RacGap (MgcRacGAP) and similar proteins
    3. XM_038438223.1XP_038294151.1  rac GTPase-activating protein 1 isoform X1

      UniProtKB/TrEMBL
      A0A8C0KNK3, A0A8C0KNV2, A0A8I3PA63, A0A8P0SDH2
      Related
      ENSCAFP00845024997.1, ENSCAFT00845031965.1
      Conserved Domains (3) summary
      cd04382
      Location:346539
      RhoGAP_MgcRacGAP; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in MgcRacGAP proteins. MgcRacGAP plays an important dual role in cytokinesis: i) it is part of centralspindlin-complex, together with the mitotic kinesin MKLP1, which is ...
      TIGR02168
      Location:13105
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      cd20821
      Location:285338
      C1_MgcRacGAP; protein kinase C conserved region 1 (C1 domain) found in male germ cell RacGap (MgcRacGAP) and similar proteins
    4. XM_038438226.1XP_038294154.1  rac GTPase-activating protein 1 isoform X1

      UniProtKB/TrEMBL
      A0A8C0KNK3, A0A8C0KNV2, A0A8I3PA63, A0A8P0SDH2
      Conserved Domains (3) summary
      cd04382
      Location:346539
      RhoGAP_MgcRacGAP; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in MgcRacGAP proteins. MgcRacGAP plays an important dual role in cytokinesis: i) it is part of centralspindlin-complex, together with the mitotic kinesin MKLP1, which is ...
      TIGR02168
      Location:13105
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      cd20821
      Location:285338
      C1_MgcRacGAP; protein kinase C conserved region 1 (C1 domain) found in male germ cell RacGap (MgcRacGAP) and similar proteins
    5. XM_038438225.1XP_038294153.1  rac GTPase-activating protein 1 isoform X1

      UniProtKB/TrEMBL
      A0A8C0KNK3, A0A8C0KNV2, A0A8I3PA63, A0A8P0SDH2
      Conserved Domains (3) summary
      cd04382
      Location:346539
      RhoGAP_MgcRacGAP; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in MgcRacGAP proteins. MgcRacGAP plays an important dual role in cytokinesis: i) it is part of centralspindlin-complex, together with the mitotic kinesin MKLP1, which is ...
      TIGR02168
      Location:13105
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      cd20821
      Location:285338
      C1_MgcRacGAP; protein kinase C conserved region 1 (C1 domain) found in male germ cell RacGap (MgcRacGAP) and similar proteins
    6. XM_038438227.1XP_038294155.1  rac GTPase-activating protein 1 isoform X2

      UniProtKB/TrEMBL
      A0A8C0KNV2
      Conserved Domains (2) summary
      cd04382
      Location:253446
      RhoGAP_MgcRacGAP; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in MgcRacGAP proteins. MgcRacGAP plays an important dual role in cytokinesis: i) it is part of centralspindlin-complex, together with the mitotic kinesin MKLP1, which is ...
      cd20821
      Location:192245
      C1_MgcRacGAP; protein kinase C conserved region 1 (C1 domain) found in male germ cell RacGap (MgcRacGAP) and similar proteins

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049287.1 Alternate UMICH_Zoey_3.1

      Range
      4702991..4731034
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038512926.1XP_038368854.1  rac GTPase-activating protein 1 isoform X1

      Conserved Domains (3) summary
      cd04382
      Location:346539
      RhoGAP_MgcRacGAP; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in MgcRacGAP proteins. MgcRacGAP plays an important dual role in cytokinesis: i) it is part of centralspindlin-complex, together with the mitotic kinesin MKLP1, which is ...
      TIGR02168
      Location:13105
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      cd20821
      Location:285338
      C1_MgcRacGAP; protein kinase C conserved region 1 (C1 domain) found in male germ cell RacGap (MgcRacGAP) and similar proteins
    2. XM_038512930.1XP_038368858.1  rac GTPase-activating protein 1 isoform X1

      Conserved Domains (3) summary
      cd04382
      Location:346539
      RhoGAP_MgcRacGAP; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in MgcRacGAP proteins. MgcRacGAP plays an important dual role in cytokinesis: i) it is part of centralspindlin-complex, together with the mitotic kinesin MKLP1, which is ...
      TIGR02168
      Location:13105
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      cd20821
      Location:285338
      C1_MgcRacGAP; protein kinase C conserved region 1 (C1 domain) found in male germ cell RacGap (MgcRacGAP) and similar proteins
    3. XM_038512924.1XP_038368852.1  rac GTPase-activating protein 1 isoform X1

      Conserved Domains (3) summary
      cd04382
      Location:346539
      RhoGAP_MgcRacGAP; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in MgcRacGAP proteins. MgcRacGAP plays an important dual role in cytokinesis: i) it is part of centralspindlin-complex, together with the mitotic kinesin MKLP1, which is ...
      TIGR02168
      Location:13105
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      cd20821
      Location:285338
      C1_MgcRacGAP; protein kinase C conserved region 1 (C1 domain) found in male germ cell RacGap (MgcRacGAP) and similar proteins
    4. XM_038512928.1XP_038368856.1  rac GTPase-activating protein 1 isoform X1

      Conserved Domains (3) summary
      cd04382
      Location:346539
      RhoGAP_MgcRacGAP; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in MgcRacGAP proteins. MgcRacGAP plays an important dual role in cytokinesis: i) it is part of centralspindlin-complex, together with the mitotic kinesin MKLP1, which is ...
      TIGR02168
      Location:13105
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      cd20821
      Location:285338
      C1_MgcRacGAP; protein kinase C conserved region 1 (C1 domain) found in male germ cell RacGap (MgcRacGAP) and similar proteins
    5. XM_038512927.1XP_038368855.1  rac GTPase-activating protein 1 isoform X1

      Conserved Domains (3) summary
      cd04382
      Location:346539
      RhoGAP_MgcRacGAP; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in MgcRacGAP proteins. MgcRacGAP plays an important dual role in cytokinesis: i) it is part of centralspindlin-complex, together with the mitotic kinesin MKLP1, which is ...
      TIGR02168
      Location:13105
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      cd20821
      Location:285338
      C1_MgcRacGAP; protein kinase C conserved region 1 (C1 domain) found in male germ cell RacGap (MgcRacGAP) and similar proteins
    6. XM_038512929.1XP_038368857.1  rac GTPase-activating protein 1 isoform X2

      Conserved Domains (2) summary
      cd04382
      Location:253446
      RhoGAP_MgcRacGAP; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in MgcRacGAP proteins. MgcRacGAP plays an important dual role in cytokinesis: i) it is part of centralspindlin-complex, together with the mitotic kinesin MKLP1, which is ...
      cd20821
      Location:192245
      C1_MgcRacGAP; protein kinase C conserved region 1 (C1 domain) found in male germ cell RacGap (MgcRacGAP) and similar proteins

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049768.1 Alternate UNSW_CanFamBas_1.0

      Range
      4692808..4720859
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038640697.1XP_038496625.1  rac GTPase-activating protein 1 isoform X1

      Conserved Domains (3) summary
      cd04382
      Location:346539
      RhoGAP_MgcRacGAP; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in MgcRacGAP proteins. MgcRacGAP plays an important dual role in cytokinesis: i) it is part of centralspindlin-complex, together with the mitotic kinesin MKLP1, which is ...
      TIGR02168
      Location:13105
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      cd20821
      Location:285338
      C1_MgcRacGAP; protein kinase C conserved region 1 (C1 domain) found in male germ cell RacGap (MgcRacGAP) and similar proteins
    2. XM_038640701.1XP_038496629.1  rac GTPase-activating protein 1 isoform X1

      Conserved Domains (3) summary
      cd04382
      Location:346539
      RhoGAP_MgcRacGAP; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in MgcRacGAP proteins. MgcRacGAP plays an important dual role in cytokinesis: i) it is part of centralspindlin-complex, together with the mitotic kinesin MKLP1, which is ...
      TIGR02168
      Location:13105
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      cd20821
      Location:285338
      C1_MgcRacGAP; protein kinase C conserved region 1 (C1 domain) found in male germ cell RacGap (MgcRacGAP) and similar proteins
    3. XM_038640696.1XP_038496624.1  rac GTPase-activating protein 1 isoform X1

      Conserved Domains (3) summary
      cd04382
      Location:346539
      RhoGAP_MgcRacGAP; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in MgcRacGAP proteins. MgcRacGAP plays an important dual role in cytokinesis: i) it is part of centralspindlin-complex, together with the mitotic kinesin MKLP1, which is ...
      TIGR02168
      Location:13105
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      cd20821
      Location:285338
      C1_MgcRacGAP; protein kinase C conserved region 1 (C1 domain) found in male germ cell RacGap (MgcRacGAP) and similar proteins
    4. XM_038640699.1XP_038496627.1  rac GTPase-activating protein 1 isoform X1

      Conserved Domains (3) summary
      cd04382
      Location:346539
      RhoGAP_MgcRacGAP; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in MgcRacGAP proteins. MgcRacGAP plays an important dual role in cytokinesis: i) it is part of centralspindlin-complex, together with the mitotic kinesin MKLP1, which is ...
      TIGR02168
      Location:13105
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      cd20821
      Location:285338
      C1_MgcRacGAP; protein kinase C conserved region 1 (C1 domain) found in male germ cell RacGap (MgcRacGAP) and similar proteins
    5. XM_038640698.1XP_038496626.1  rac GTPase-activating protein 1 isoform X1

      Conserved Domains (3) summary
      cd04382
      Location:346539
      RhoGAP_MgcRacGAP; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in MgcRacGAP proteins. MgcRacGAP plays an important dual role in cytokinesis: i) it is part of centralspindlin-complex, together with the mitotic kinesin MKLP1, which is ...
      TIGR02168
      Location:13105
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      cd20821
      Location:285338
      C1_MgcRacGAP; protein kinase C conserved region 1 (C1 domain) found in male germ cell RacGap (MgcRacGAP) and similar proteins
    6. XM_038640700.1XP_038496628.1  rac GTPase-activating protein 1 isoform X2

      Conserved Domains (2) summary
      cd04382
      Location:253446
      RhoGAP_MgcRacGAP; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in MgcRacGAP proteins. MgcRacGAP plays an important dual role in cytokinesis: i) it is part of centralspindlin-complex, together with the mitotic kinesin MKLP1, which is ...
      cd20821
      Location:192245
      C1_MgcRacGAP; protein kinase C conserved region 1 (C1 domain) found in male germ cell RacGap (MgcRacGAP) and similar proteins

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049248.1 Alternate UU_Cfam_GSD_1.0

      Range
      41935897..41964171 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038577615.1XP_038433543.1  rac GTPase-activating protein 1 isoform X1

      UniProtKB/TrEMBL
      A0A8C0KNV2
    2. XM_038577613.1XP_038433541.1  rac GTPase-activating protein 1 isoform X1

      UniProtKB/TrEMBL
      A0A8C0KNV2
    3. XM_038577614.1XP_038433542.1  rac GTPase-activating protein 1 isoform X1

      UniProtKB/TrEMBL
      A0A8C0KNV2
    4. XM_038577617.1XP_038433545.1  rac GTPase-activating protein 1 isoform X1

      UniProtKB/TrEMBL
      A0A8C0KNV2
    5. XM_038577616.1XP_038433544.1  rac GTPase-activating protein 1 isoform X1

      UniProtKB/TrEMBL
      A0A8C0KNV2
    6. XM_038577618.1XP_038433546.1  rac GTPase-activating protein 1 isoform X2

      UniProtKB/TrEMBL
      A0A8C0KNV2

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006609.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      41541242..41569279 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005636864.3XP_005636921.2  rac GTPase-activating protein 1 isoform X1

      UniProtKB/TrEMBL
      A0A8C0KNK3, A0A8C0KNV2, A0A8I3PA63, A0A8P0SDH2
      Conserved Domains (3) summary
      cd04382
      Location:346539
      RhoGAP_MgcRacGAP; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in MgcRacGAP proteins. MgcRacGAP plays an important dual role in cytokinesis: i) it is part of centralspindlin-complex, together with the mitotic kinesin MKLP1, which is ...
      TIGR02168
      Location:13105
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      cd20821
      Location:285338
      C1_MgcRacGAP; protein kinase C conserved region 1 (C1 domain) found in male germ cell RacGap (MgcRacGAP) and similar proteins
    2. XM_005636863.4XP_005636920.2  rac GTPase-activating protein 1 isoform X1

      UniProtKB/TrEMBL
      A0A8C0KNK3, A0A8C0KNV2, A0A8I3PA63, A0A8P0SDH2
      Conserved Domains (3) summary
      cd04382
      Location:346539
      RhoGAP_MgcRacGAP; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in MgcRacGAP proteins. MgcRacGAP plays an important dual role in cytokinesis: i) it is part of centralspindlin-complex, together with the mitotic kinesin MKLP1, which is ...
      TIGR02168
      Location:13105
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      cd20821
      Location:285338
      C1_MgcRacGAP; protein kinase C conserved region 1 (C1 domain) found in male germ cell RacGap (MgcRacGAP) and similar proteins
    3. XM_005636865.4XP_005636922.2  rac GTPase-activating protein 1 isoform X1

      UniProtKB/TrEMBL
      A0A8C0KNK3, A0A8C0KNV2, A0A8I3PA63, A0A8P0SDH2
      Conserved Domains (3) summary
      cd04382
      Location:346539
      RhoGAP_MgcRacGAP; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in MgcRacGAP proteins. MgcRacGAP plays an important dual role in cytokinesis: i) it is part of centralspindlin-complex, together with the mitotic kinesin MKLP1, which is ...
      TIGR02168
      Location:13105
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      cd20821
      Location:285338
      C1_MgcRacGAP; protein kinase C conserved region 1 (C1 domain) found in male germ cell RacGap (MgcRacGAP) and similar proteins
    4. XM_543675.7XP_543675.3  rac GTPase-activating protein 1 isoform X1

      UniProtKB/TrEMBL
      A0A8C0KNK3, A0A8C0KNV2, A0A8I3PA63, A0A8P0SDH2
      Conserved Domains (3) summary
      cd04382
      Location:346539
      RhoGAP_MgcRacGAP; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in MgcRacGAP proteins. MgcRacGAP plays an important dual role in cytokinesis: i) it is part of centralspindlin-complex, together with the mitotic kinesin MKLP1, which is ...
      TIGR02168
      Location:13105
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      cd20821
      Location:285338
      C1_MgcRacGAP; protein kinase C conserved region 1 (C1 domain) found in male germ cell RacGap (MgcRacGAP) and similar proteins
    5. XM_022411182.2XP_022266890.2  rac GTPase-activating protein 1 isoform X1

      UniProtKB/TrEMBL
      A0A8C0KNK3, A0A8C0KNV2, A0A8I3PA63, A0A8P0SDH2
      Conserved Domains (3) summary
      cd04382
      Location:346539
      RhoGAP_MgcRacGAP; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in MgcRacGAP proteins. MgcRacGAP plays an important dual role in cytokinesis: i) it is part of centralspindlin-complex, together with the mitotic kinesin MKLP1, which is ...
      TIGR02168
      Location:13105
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      cd20821
      Location:285338
      C1_MgcRacGAP; protein kinase C conserved region 1 (C1 domain) found in male germ cell RacGap (MgcRacGAP) and similar proteins
    6. XM_014108730.3XP_013964205.2  rac GTPase-activating protein 1 isoform X2

      UniProtKB/TrEMBL
      A0A8C0KNV2
      Conserved Domains (2) summary
      cd04382
      Location:253446
      RhoGAP_MgcRacGAP; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in MgcRacGAP proteins. MgcRacGAP plays an important dual role in cytokinesis: i) it is part of centralspindlin-complex, together with the mitotic kinesin MKLP1, which is ...
      cd20821
      Location:192245
      C1_MgcRacGAP; protein kinase C conserved region 1 (C1 domain) found in male germ cell RacGap (MgcRacGAP) and similar proteins