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    MC3R melanocortin 3 receptor [ Canis lupus familiaris (dog) ]

    Gene ID: 485938, updated on 17-Aug-2024

    Summary

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    Official Symbol
    MC3Rprovided by VGNC
    Official Full Name
    melanocortin 3 receptorprovided by VGNC
    Primary source
    VGNC:VGNC:110518
    See related
    Ensembl:ENSCAFG00845029148
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Orthologs
    human mouse all
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    Genomic context

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    See MC3R in Genome Data Viewer
    Location:
    chromosome: 24
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 24 NC_051828.1 (42204101..42206852)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 24 NC_006606.4 (40740767..40742429)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 24 NC_049245.1 (42240608..42242272)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 24 NC_049284.1 (41443631..41445290)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 24 NC_049765.1 (41583159..41584826)

    Chromosome 24 - NC_051828.1Genomic Context describing neighboring genes Neighboring gene biliverdin reductase A-like Neighboring gene cerebellin 4 precursor Neighboring gene uncharacterized LOC111092149 Neighboring gene uncharacterized LOC119865566

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Melanocortin 3 receptor has a 5' exon that directs translation of apically localized protein from the second in-frame ATG. Park J, et al. Mol Endocrinol, 2014 Sep. PMID 25051171, Free PMC Article

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. MC3R is a 2-exon gene that requires a 5' UTR for translation, localization, and potential interaction with MRAP2
      Title: Melanocortin 3 receptor has a 5' exon that directs translation of apically localized protein from the second in-frame ATG.
    Submit: New GeneRIF Correction

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables melanocyte-stimulating hormone receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables peptide hormone binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in G protein-coupled receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    melanocortin receptor 3

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001135124.1 → NP_001128596.1  melanocortin receptor 3

      See identical proteins and their annotated locations for NP_001128596.1

      Status: PROVISIONAL

      Source sequence(s)
      FJ005193
      UniProtKB/TrEMBL
      A0A8C0LCJ1, A0A8C0PID6, A0A8P0NTM1, B5TQW3
      Related
      ENSCAFP00845040470.1, ENSCAFT00845051577.1
      Conserved Domains (1) summary
      cd15352
      Location:39 → 310
      7tmA_MC3R; melanocortin receptor subtype 3, member of the class A family of seven-transmembrane G protein-coupled receptors

    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051828.1 Reference ROS_Cfam_1.0

      Range
      42204101..42206852
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038432837.1 → XP_038288765.1  melanocortin receptor 3 isoform X1

      UniProtKB/TrEMBL
      A0A8C0LCJ1, A0A8C0PID6, A0A8P0NTM1, B5TQW3
      Conserved Domains (1) summary
      cd15352
      Location:39 → 310
      7tmA_MC3R; melanocortin receptor subtype 3, member of the class A family of seven-transmembrane G protein-coupled receptors

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049284.1 Alternate UMICH_Zoey_3.1

      Range
      41443631..41445290
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049765.1 Alternate UNSW_CanFamBas_1.0

      Range
      41583159..41584826
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049245.1 Alternate UU_Cfam_GSD_1.0

      Range
      42240608..42242272
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006606.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      40740767..40742429
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version

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