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    FBXL12 F-box and leucine rich repeat protein 12 [ Canis lupus familiaris (dog) ]

    Gene ID: 484965, updated on 17-Aug-2024

    Summary

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    Official Symbol
    FBXL12provided by VGNC
    Official Full Name
    F-box and leucine rich repeat protein 12provided by VGNC
    Primary source
    VGNC:VGNC:54945
    See related
    Ensembl:ENSCAFG00845023009
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Orthologs
    human mouse all
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    Genomic context

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    See FBXL12 in Genome Data Viewer
    Location:
    chromosome: 20
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 20 NC_051824.1 (51704430..51708761)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 20 NC_006602.4 (51046830..51051154)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 20 NC_049241.1 (51578289..51582631)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 20 NC_049280.1 (50912024..50916339)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 20 NC_049761.1 (51337013..51341338)

    Chromosome 20 - NC_051824.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC102153974 Neighboring gene peptidylprolyl cis/trans isomerase, NIMA-interacting 1 Neighboring gene ubiquitin like 5 Neighboring gene zinc finger protein 846 Neighboring gene 60S ribosomal protein L15-like

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in SCF-dependent proteasomal ubiquitin-dependent protein catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of protein ubiquitination IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of SCF ubiquitin ligase complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    F-box/LRR-repeat protein 12

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051824.1 Reference ROS_Cfam_1.0

      Range
      51704430..51708761
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038428701.1 → XP_038284629.1  F-box/LRR-repeat protein 12

      UniProtKB/TrEMBL
      A0A8C0LGY7, A0A8C0PHW4, A0A8I3PHW9
      Related
      ENSCAFP00845031828.1, ENSCAFT00845040663.1
      Conserved Domains (3) summary
      sd00034
      Location:104 → 125
      LRR_AMN1; leucine-rich repeat [structural motif]
      pfam12937
      Location:4 → 48
      F-box-like
      cd21340
      Location:167 → 291
      PPP1R42; protein phosphatase 1 regulatory subunit 42

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049280.1 Alternate UMICH_Zoey_3.1

      Range
      50912024..50916339
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038504344.1 → XP_038360272.1  F-box/LRR-repeat protein 12

      Conserved Domains (3) summary
      sd00034
      Location:104 → 125
      LRR_AMN1; leucine-rich repeat [structural motif]
      pfam12937
      Location:4 → 48
      F-box-like
      cd21340
      Location:167 → 291
      PPP1R42; protein phosphatase 1 regulatory subunit 42

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049761.1 Alternate UNSW_CanFamBas_1.0

      Range
      51337013..51341338
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038631524.1 → XP_038487452.1  F-box/LRR-repeat protein 12

      Conserved Domains (3) summary
      sd00034
      Location:104 → 125
      LRR_AMN1; leucine-rich repeat [structural motif]
      pfam12937
      Location:4 → 48
      F-box-like
      cd21340
      Location:167 → 291
      PPP1R42; protein phosphatase 1 regulatory subunit 42

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049241.1 Alternate UU_Cfam_GSD_1.0

      Range
      51578289..51582631
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038567376.1 → XP_038423304.1  F-box/LRR-repeat protein 12

      UniProtKB/TrEMBL
      A0A8C0LGY7, A0A8C0PHW4, A0A8I3PHW9
      Conserved Domains (3) summary
      sd00034
      Location:104 → 125
      LRR_AMN1; leucine-rich repeat [structural motif]
      pfam12937
      Location:4 → 48
      F-box-like
      cd21340
      Location:167 → 291
      PPP1R42; protein phosphatase 1 regulatory subunit 42

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006602.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      51046830..51051154
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_542082.7 → XP_542082.4  F-box/LRR-repeat protein 12

      UniProtKB/TrEMBL
      A0A8C0LGY7, A0A8C0PHW4, A0A8I3PHW9
      Conserved Domains (3) summary
      sd00034
      Location:104 → 125
      LRR_AMN1; leucine-rich repeat [structural motif]
      pfam12937
      Location:4 → 48
      F-box-like
      cd21340
      Location:167 → 291
      PPP1R42; protein phosphatase 1 regulatory subunit 42
    Nucleotide Protein
    Heading Accession and Version

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