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    FADS1 fatty acid desaturase 1 [ Canis lupus familiaris (dog) ]

    Gene ID: 483793, updated on 17-Aug-2024

    Summary

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    Official Symbol
    FADS1provided by VGNC
    Official Full Name
    fatty acid desaturase 1provided by VGNC
    Primary source
    VGNC:VGNC:51870
    See related
    Ensembl:ENSCAFG00845011265
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Orthologs
    human mouse all
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    Genomic context

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    See FADS1 in Genome Data Viewer
    Location:
    chromosome: 18
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 18 NC_051822.1 (55712876..55726262)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 18 NC_006600.4 (53240872..53254256)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 18 NC_049239.1 (55262070..55273351)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 18 NC_049278.1 (54773452..54786834)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 18 NC_049759.1 (54394906..54406186)

    Chromosome 18 - NC_051822.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC111091016 Neighboring gene dnaJ homolog subfamily A member 1-like Neighboring gene uncharacterized LOC111091015 Neighboring gene transmembrane protein 258 Neighboring gene flap structure-specific endonuclease 1 Neighboring gene myelin regulatory factor

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in lipid metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    fatty acid desaturase 1; acyl-CoA (8-3)-desaturase

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051822.1 Reference ROS_Cfam_1.0

      Range
      55712876..55726262
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038425393.1 → XP_038281321.1  acyl-CoA (8-3)-desaturase isoform X1

      UniProtKB/TrEMBL
      A0A8C0KIA4
      Related
      ENSCAFP00845015677.1, ENSCAFT00845020011.1
      Conserved Domains (2) summary
      PLN03199
      Location:15 → 437
      PLN03199; delta6-acyl-lipid desaturase-like protein; Provisional
      cd03506
      Location:159 → 410
      Delta6-FADS-like; The Delta6 Fatty Acid Desaturase (Delta6-FADS)-like CD includes the integral-membrane enzymes: delta-4, delta-5, delta-6, delta-8, delta-8-sphingolipid, and delta-11 desaturases found in vertebrates, higher plants, fungi, and bacteria. These desaturases ...

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049278.1 Alternate UMICH_Zoey_3.1

      Range
      54773452..54786834
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038501629.1 → XP_038357557.1  acyl-CoA (8-3)-desaturase isoform X1

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049759.1 Alternate UNSW_CanFamBas_1.0

      Range
      54394906..54406186
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038628484.1 → XP_038484412.1  acyl-CoA (8-3)-desaturase isoform X1

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049239.1 Alternate UU_Cfam_GSD_1.0

      Range
      55262070..55273351
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038564347.1 → XP_038420275.1  acyl-CoA (8-3)-desaturase isoform X1

      UniProtKB/TrEMBL
      A0A8C0KFP6, A0A8C0KIA4

    2. XM_038564348.1 → XP_038420276.1  acyl-CoA (8-3)-desaturase isoform X2

      UniProtKB/TrEMBL
      A0A8C0PDS1
      Conserved Domains (1) summary
      cd03506
      Location:90 → 341
      Delta6-FADS-like; The Delta6 Fatty Acid Desaturase (Delta6-FADS)-like CD includes the integral-membrane enzymes: delta-4, delta-5, delta-6, delta-8, delta-8-sphingolipid, and delta-11 desaturases found in vertebrates, higher plants, fungi, and bacteria. These desaturases ...

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006600.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      53240872..53254256
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_014120903.3 → XP_013976378.2  acyl-CoA (8-3)-desaturase isoform X1

      UniProtKB/TrEMBL
      A0A8C0KIA4
      Conserved Domains (2) summary
      PLN03199
      Location:15 → 437
      PLN03199; delta6-acyl-lipid desaturase-like protein; Provisional
      cd03506
      Location:159 → 410
      Delta6-FADS-like; The Delta6 Fatty Acid Desaturase (Delta6-FADS)-like CD includes the integral-membrane enzymes: delta-4, delta-5, delta-6, delta-8, delta-8-sphingolipid, and delta-11 desaturases found in vertebrates, higher plants, fungi, and bacteria. These desaturases ...
    Nucleotide Protein
    Heading Accession and Version

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    Research Materials