U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination
    • Showing Current items.

    PC pyruvate carboxylase [ Canis lupus familiaris (dog) ]

    Gene ID: 483704, updated on 17-Aug-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    PCprovided by VGNC
    Official Full Name
    pyruvate carboxylaseprovided by VGNC
    Primary source
    VGNC:VGNC:51885
    See related
    Ensembl:ENSCAFG00845011738
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Orthologs
    human mouse all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    Location:
    chromosome: 18
    Exon count:
    25
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 18 NC_051822.1 (51357399..51457857)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 18 NC_006600.4 (49016958..49117517)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 18 NC_049239.1 (50910958..51011409)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 18 NC_049278.1 (50541749..50642299)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 18 NC_049759.1 (50121287..50221660)

    Chromosome 18 - NC_051822.1Genomic Context describing neighboring genes Neighboring gene lateral signaling target protein 2 homolog Neighboring gene chromosome 18 C11orf86 homolog Neighboring gene uncharacterized LOC111090994 Neighboring gene leucine rich repeat and fibronectin type III domain containing 4 Neighboring gene TOP6B like initiator of meiotic double strand breaks Neighboring gene Ras converting CAAX endopeptidase 1

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Light-activated BioID - an optically activated proximity labeling system to study protein-protein interactions. Shafraz O, et al. J Cell Sci, 2023 Oct 1. PMID 37756605, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables pyruvate carboxylase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in gluconeogenesis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in pyruvate metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    pyruvate carboxylase, mitochondrial
    XP_005631472.1
    XP_005631473.1
    XP_038280769.1
    XP_038280770.1
    XP_038280771.1
    XP_038280772.1
    XP_038310442.1
    XP_038357013.1
    XP_038357014.1
    XP_038357015.1
    XP_038357016.1
    XP_038419712.1
    XP_038419713.1
    XP_038419714.1
    XP_038419715.1
    XP_038483830.1
    XP_038483831.1
    XP_038483832.1
    XP_038483833.1
    XP_540825.2

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051822.1 Reference ROS_Cfam_1.0

      Range
      51357399..51457857
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038424843.1 → XP_038280771.1  pyruvate carboxylase, mitochondrial isoform X1

      UniProtKB/TrEMBL
      A0A8C0NP94
      Related
      ENSCAFP00845016350.1, ENSCAFT00845020828.1
      Conserved Domains (1) summary
      PRK12999
      Location:33 → 1178
      PRK12999; pyruvate carboxylase; Reviewed

    2. XM_038424842.1 → XP_038280770.1  pyruvate carboxylase, mitochondrial isoform X2

      UniProtKB/TrEMBL
      A0A8C0NP94, A0A8I3NKZ1, A0A8P0PBZ5
      Related
      ENSCAFP00845016398.1, ENSCAFT00845020879.1
      Conserved Domains (1) summary
      PRK12999
      Location:45 → 1190
      PRK12999; pyruvate carboxylase; Reviewed

    3. XM_038424841.1 → XP_038280769.1  pyruvate carboxylase, mitochondrial isoform X1

      UniProtKB/TrEMBL
      A0A8C0NP94
      Conserved Domains (1) summary
      PRK12999
      Location:33 → 1178
      PRK12999; pyruvate carboxylase; Reviewed

    4. XM_038424844.1 → XP_038280772.1  pyruvate carboxylase, mitochondrial isoform X1

      UniProtKB/TrEMBL
      A0A8C0NP94
      Conserved Domains (1) summary
      PRK12999
      Location:33 → 1178
      PRK12999; pyruvate carboxylase; Reviewed

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049278.1 Alternate UMICH_Zoey_3.1

      Range
      50541749..50642299
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038501087.1 → XP_038357015.1  pyruvate carboxylase, mitochondrial isoform X1

      Conserved Domains (1) summary
      PRK12999
      Location:33 → 1178
      PRK12999; pyruvate carboxylase; Reviewed

    2. XM_038501086.1 → XP_038357014.1  pyruvate carboxylase, mitochondrial isoform X2

      Conserved Domains (1) summary
      PRK12999
      Location:45 → 1190
      PRK12999; pyruvate carboxylase; Reviewed

    3. XM_038501085.1 → XP_038357013.1  pyruvate carboxylase, mitochondrial isoform X1

      Conserved Domains (1) summary
      PRK12999
      Location:33 → 1178
      PRK12999; pyruvate carboxylase; Reviewed

    4. XM_038501088.1 → XP_038357016.1  pyruvate carboxylase, mitochondrial isoform X1

      Conserved Domains (1) summary
      PRK12999
      Location:33 → 1178
      PRK12999; pyruvate carboxylase; Reviewed

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049759.1 Alternate UNSW_CanFamBas_1.0

      Range
      50121287..50221660
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038627904.1 → XP_038483832.1  pyruvate carboxylase, mitochondrial isoform X1

      Conserved Domains (1) summary
      PRK12999
      Location:33 → 1178
      PRK12999; pyruvate carboxylase; Reviewed

    2. XM_038627903.1 → XP_038483831.1  pyruvate carboxylase, mitochondrial isoform X2

      Conserved Domains (1) summary
      PRK12999
      Location:45 → 1190
      PRK12999; pyruvate carboxylase; Reviewed

    3. XM_038627902.1 → XP_038483830.1  pyruvate carboxylase, mitochondrial isoform X1

      Conserved Domains (1) summary
      PRK12999
      Location:33 → 1178
      PRK12999; pyruvate carboxylase; Reviewed

    4. XM_038627905.1 → XP_038483833.1  pyruvate carboxylase, mitochondrial isoform X1

      Conserved Domains (1) summary
      PRK12999
      Location:33 → 1178
      PRK12999; pyruvate carboxylase; Reviewed

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049239.1 Alternate UU_Cfam_GSD_1.0

      Range
      50910958..51011409
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038563786.1 → XP_038419714.1  pyruvate carboxylase, mitochondrial isoform X1

      UniProtKB/TrEMBL
      A0A8C0NP94
      Conserved Domains (1) summary
      PRK12999
      Location:33 → 1178
      PRK12999; pyruvate carboxylase; Reviewed

    2. XM_038563785.1 → XP_038419713.1  pyruvate carboxylase, mitochondrial isoform X2

      UniProtKB/TrEMBL
      A0A8C0NP94, A0A8I3NKZ1, A0A8P0PBZ5
      Conserved Domains (1) summary
      PRK12999
      Location:45 → 1190
      PRK12999; pyruvate carboxylase; Reviewed

    3. XM_038563784.1 → XP_038419712.1  pyruvate carboxylase, mitochondrial isoform X1

      UniProtKB/TrEMBL
      A0A8C0NP94
      Conserved Domains (1) summary
      PRK12999
      Location:33 → 1178
      PRK12999; pyruvate carboxylase; Reviewed

    4. XM_038563787.1 → XP_038419715.1  pyruvate carboxylase, mitochondrial isoform X1

      UniProtKB/TrEMBL
      A0A8C0NP94
      Conserved Domains (1) summary
      PRK12999
      Location:33 → 1178
      PRK12999; pyruvate carboxylase; Reviewed

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006600.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      49016958..49117517
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_540825.7 → XP_540825.2  pyruvate carboxylase, mitochondrial isoform X1

      See identical proteins and their annotated locations for XP_540825.2

      UniProtKB/TrEMBL
      A0A8C0NP94
      Conserved Domains (1) summary
      PRK12999
      Location:33 → 1178
      PRK12999; pyruvate carboxylase; Reviewed

    2. XM_005631415.4 → XP_005631472.1  pyruvate carboxylase, mitochondrial isoform X2

      UniProtKB/TrEMBL
      A0A8C0NP94, A0A8I3NKZ1, A0A8P0PBZ5
      Conserved Domains (1) summary
      PRK12999
      Location:45 → 1190
      PRK12999; pyruvate carboxylase; Reviewed

    3. XM_038454514.1 → XP_038310442.1  pyruvate carboxylase, mitochondrial isoform X1

      UniProtKB/TrEMBL
      A0A8C0NP94
      Conserved Domains (1) summary
      PRK12999
      Location:33 → 1178
      PRK12999; pyruvate carboxylase; Reviewed

    4. XM_005631416.4 → XP_005631473.1  pyruvate carboxylase, mitochondrial isoform X1

      See identical proteins and their annotated locations for XP_005631473.1

      UniProtKB/TrEMBL
      A0A8C0NP94
      Conserved Domains (1) summary
      PRK12999
      Location:33 → 1178
      PRK12999; pyruvate carboxylase; Reviewed
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.