U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination
    • Showing Current items.

    GLI3 GLI family zinc finger 3 [ Canis lupus familiaris (dog) ]

    Gene ID: 483244, updated on 17-Aug-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    GLI3provided by VGNC
    Official Full Name
    GLI family zinc finger 3provided by VGNC
    Primary source
    VGNC:VGNC:41258
    See related
    Ensembl:ENSCAFG00845018240
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Orthologs
    human mouse all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See GLI3 in Genome Data Viewer
    Location:
    chromosome: 18
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 18 NC_051822.1 (7847548..8118213)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 18 NC_006600.4 (7651291..7921706)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 18 NC_049239.1 (7912805..8183294)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 18 NC_049278.1 (7829563..8099968)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 18 NC_049759.1 (7798494..8068961)

    Chromosome 18 - NC_051822.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC119864095 Neighboring gene uncharacterized LOC119864159 Neighboring gene uncharacterized LOC119864158 Neighboring gene uncharacterized LOC119864160 Neighboring gene uncharacterized LOC111090866 Neighboring gene uncharacterized LOC119864096 Neighboring gene uncharacterized LOC119864097

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

    Go to the top of the page

    General gene information

    Go to the top of the page Help

    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in smoothened signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    zinc finger protein GLI3; LOW QUALITY PROTEIN: transcriptional activator GLI3; transcriptional activator GLI3
    Names
    GLI-Kruppel family member GLI3 (Greig cephalopolysyndactyly syndrome)

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051822.1 Reference ROS_Cfam_1.0

      Range
      7847548..8118213
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038423703.1 → XP_038279631.1  transcriptional activator GLI3

      UniProtKB/TrEMBL
      A0A8C0LC73, A0A8C0S0Q7, A0A8I3P2B2
      Related
      ENSCAFP00845025228.1, ENSCAFT00845032272.1
      Conserved Domains (4) summary
      COG5048
      Location:278 → 626
      COG5048; FOG: Zn-finger [General function prediction only]
      COG5189
      Location:541 → 631
      SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
      PRK07764
      Location:1191 → 1306
      PRK07764; DNA polymerase III subunits gamma and tau; Validated
      sd00017
      Location:547 → 569
      ZF_C2H2; C2H2 Zn finger [structural motif]

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049278.1 Alternate UMICH_Zoey_3.1

      Range
      7829563..8099968
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038500069.1 → XP_038355997.1  transcriptional activator GLI3

      Conserved Domains (4) summary
      COG5048
      Location:278 → 626
      COG5048; FOG: Zn-finger [General function prediction only]
      COG5189
      Location:541 → 631
      SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
      PRK07764
      Location:1191 → 1306
      PRK07764; DNA polymerase III subunits gamma and tau; Validated
      sd00017
      Location:547 → 569
      ZF_C2H2; C2H2 Zn finger [structural motif]

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049759.1 Alternate UNSW_CanFamBas_1.0

      Range
      7798494..8068961
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038626733.1 → XP_038482661.1  LOW QUALITY PROTEIN: transcriptional activator GLI3

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049239.1 Alternate UU_Cfam_GSD_1.0

      Range
      7912805..8183294
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038562653.1 → XP_038418581.1  transcriptional activator GLI3

      UniProtKB/TrEMBL
      A0A8C0LC73, A0A8C0S0Q7, A0A8I3P2B2
      Conserved Domains (4) summary
      COG5048
      Location:278 → 626
      COG5048; FOG: Zn-finger [General function prediction only]
      COG5189
      Location:541 → 631
      SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
      PRK07764
      Location:1191 → 1306
      PRK07764; DNA polymerase III subunits gamma and tau; Validated
      sd00017
      Location:547 → 569
      ZF_C2H2; C2H2 Zn finger [structural motif]

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006600.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      7651291..7921706
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038454031.1 → XP_038309959.1  transcriptional activator GLI3

      UniProtKB/TrEMBL
      A0A8C0LC73, A0A8P0NQW6
      Conserved Domains (4) summary
      COG5048
      Location:278 → 626
      COG5048; FOG: Zn-finger [General function prediction only]
      COG5189
      Location:541 → 631
      SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
      PRK07764
      Location:1191 → 1306
      PRK07764; DNA polymerase III subunits gamma and tau; Validated
      sd00017
      Location:547 → 569
      ZF_C2H2; C2H2 Zn finger [structural motif]
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials