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    CAPN14 calpain 14 [ Canis lupus familiaris (dog) ]

    Gene ID: 483026, updated on 17-Aug-2024

    Summary

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    Official Symbol
    CAPN14provided by VGNC
    Official Full Name
    calpain 14provided by VGNC
    Primary source
    VGNC:VGNC:38702
    See related
    Ensembl:ENSCAFG00845012156
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Orthologs
    human all
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    Genomic context

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    See CAPN14 in Genome Data Viewer
    Location:
    chromosome: 17
    Exon count:
    27
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 17 NC_051821.1 (25338344..25378171, complement)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 17 NC_006599.4 (24568877..24608698, complement)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 17 NC_049238.1 (24803646..24843487, complement)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 17 NC_049277.1 (24641601..24681433, complement)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 17 NC_049758.1 (24703580..24743527, complement)

    Chromosome 17 - NC_051821.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC119869804 Neighboring gene polypeptide N-acetylgalactosaminyltransferase 14 Neighboring gene uncharacterized LOC119869778 Neighboring gene uncharacterized LOC119869732 Neighboring gene uncharacterized LOC111090424 Neighboring gene EH domain containing 3

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables calcium ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables calcium-dependent cysteine-type endopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in proteolysis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    calpain-14
    XP_022260325.1
    XP_038309195.1
    XP_038309196.1
    XP_038355826.1
    XP_038355827.1
    XP_038355828.1
    XP_038416517.1
    XP_038416518.1
    XP_038416519.1
    XP_038480542.1
    XP_038480543.1
    XP_038480544.1
    XP_038546457.1
    XP_038546458.1
    XP_038546459.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051821.1 Reference ROS_Cfam_1.0

      Range
      25338344..25378171 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038690529.1 → XP_038546457.1  calpain-14 isoform X1

      UniProtKB/TrEMBL
      A0A8I3NLB8, A0A8P0SSI6
      Related
      ENSCAFP00845017105.1, ENSCAFT00845021752.1
      Conserved Domains (3) summary
      cd16195
      Location:583 → 750
      EFh_PEF_CAPN13_14; Penta-EF hand, calcium binding motifs, found in calpain-13 (CAPN13), calpain-14 (CAPN14), and similar proteins
      pfam00648
      Location:108 → 399
      Peptidase_C2; Calpain family cysteine protease
      pfam01067
      Location:420 → 556
      Calpain_III; Calpain large subunit, domain III

    2. XM_038690531.1 → XP_038546459.1  calpain-14 isoform X2

      UniProtKB/TrEMBL
      A0A8C0SCW2, A0A8I3NAT4
      Related
      ENSCAFP00845017126.1, ENSCAFT00845021775.1
      Conserved Domains (3) summary
      cd16195
      Location:519 → 686
      EFh_PEF_CAPN13_14; Penta-EF hand, calcium binding motifs, found in calpain-13 (CAPN13), calpain-14 (CAPN14), and similar proteins
      pfam00648
      Location:44 → 335
      Peptidase_C2; Calpain family cysteine protease
      pfam01067
      Location:356 → 492
      Calpain_III; Calpain large subunit, domain III

    3. XM_038690530.1 → XP_038546458.1  calpain-14 isoform X2

      UniProtKB/TrEMBL
      A0A8C0SCW2, A0A8I3NAT4
      Conserved Domains (3) summary
      cd16195
      Location:519 → 686
      EFh_PEF_CAPN13_14; Penta-EF hand, calcium binding motifs, found in calpain-13 (CAPN13), calpain-14 (CAPN14), and similar proteins
      pfam00648
      Location:44 → 335
      Peptidase_C2; Calpain family cysteine protease
      pfam01067
      Location:356 → 492
      Calpain_III; Calpain large subunit, domain III

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049277.1 Alternate UMICH_Zoey_3.1

      Range
      24641601..24681433 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038499898.1 → XP_038355826.1  calpain-14 isoform X1

      Conserved Domains (3) summary
      cd16195
      Location:583 → 750
      EFh_PEF_CAPN13_14; Penta-EF hand, calcium binding motifs, found in calpain-13 (CAPN13), calpain-14 (CAPN14), and similar proteins
      pfam00648
      Location:108 → 399
      Peptidase_C2; Calpain family cysteine protease
      pfam01067
      Location:420 → 556
      Calpain_III; Calpain large subunit, domain III

    2. XM_038499900.1 → XP_038355828.1  calpain-14 isoform X2

      Conserved Domains (3) summary
      cd16195
      Location:519 → 686
      EFh_PEF_CAPN13_14; Penta-EF hand, calcium binding motifs, found in calpain-13 (CAPN13), calpain-14 (CAPN14), and similar proteins
      pfam00648
      Location:44 → 335
      Peptidase_C2; Calpain family cysteine protease
      pfam01067
      Location:356 → 492
      Calpain_III; Calpain large subunit, domain III

    3. XM_038499899.1 → XP_038355827.1  calpain-14 isoform X2

      Conserved Domains (3) summary
      cd16195
      Location:519 → 686
      EFh_PEF_CAPN13_14; Penta-EF hand, calcium binding motifs, found in calpain-13 (CAPN13), calpain-14 (CAPN14), and similar proteins
      pfam00648
      Location:44 → 335
      Peptidase_C2; Calpain family cysteine protease
      pfam01067
      Location:356 → 492
      Calpain_III; Calpain large subunit, domain III

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049758.1 Alternate UNSW_CanFamBas_1.0

      Range
      24703580..24743527 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038624614.1 → XP_038480542.1  calpain-14 isoform X1

    2. XM_038624616.1 → XP_038480544.1  calpain-14 isoform X2

    3. XM_038624615.1 → XP_038480543.1  calpain-14 isoform X2

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049238.1 Alternate UU_Cfam_GSD_1.0

      Range
      24803646..24843487 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038560589.1 → XP_038416517.1  calpain-14 isoform X1

      UniProtKB/TrEMBL
      A0A8I3NLB8, A0A8P0SSI6

    2. XM_038560591.1 → XP_038416519.1  calpain-14 isoform X2

      UniProtKB/TrEMBL
      A0A8C0NDJ1

    3. XM_038560590.1 → XP_038416518.1  calpain-14 isoform X2

      UniProtKB/TrEMBL
      A0A8C0NDJ1

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006599.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      24568877..24608698 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_022404617.2 → XP_022260325.1  calpain-14 isoform X1

      UniProtKB/TrEMBL
      A0A8I3NLB8, A0A8P0SSI6
      Conserved Domains (3) summary
      cd16195
      Location:583 → 750
      EFh_PEF_CAPN13_14; Penta-EF hand, calcium binding motifs, found in calpain-13 (CAPN13), calpain-14 (CAPN14), and similar proteins
      pfam00648
      Location:108 → 399
      Peptidase_C2; Calpain family cysteine protease
      pfam01067
      Location:420 → 556
      Calpain_III; Calpain large subunit, domain III

    2. XM_038453268.1 → XP_038309196.1  calpain-14 isoform X2

      UniProtKB/TrEMBL
      A0A8C0SCW2, A0A8I3NAT4
      Conserved Domains (3) summary
      cd16195
      Location:519 → 686
      EFh_PEF_CAPN13_14; Penta-EF hand, calcium binding motifs, found in calpain-13 (CAPN13), calpain-14 (CAPN14), and similar proteins
      pfam00648
      Location:44 → 335
      Peptidase_C2; Calpain family cysteine protease
      pfam01067
      Location:356 → 492
      Calpain_III; Calpain large subunit, domain III

    3. XM_038453267.1 → XP_038309195.1  calpain-14 isoform X2

      UniProtKB/TrEMBL
      A0A8C0SCW2, A0A8I3NAT4
      Conserved Domains (3) summary
      cd16195
      Location:519 → 686
      EFh_PEF_CAPN13_14; Penta-EF hand, calcium binding motifs, found in calpain-13 (CAPN13), calpain-14 (CAPN14), and similar proteins
      pfam00648
      Location:44 → 335
      Peptidase_C2; Calpain family cysteine protease
      pfam01067
      Location:356 → 492
      Calpain_III; Calpain large subunit, domain III
    Nucleotide Protein
    Heading Accession and Version

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