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    NPY2R neuropeptide Y receptor Y2 [ Canis lupus familiaris (dog) ]

    Gene ID: 482661, updated on 5-Mar-2024

    Summary

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    Gene symbol
    NPY2R
    Gene description
    neuropeptide Y receptor Y2
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Orthologs
    human mouse all
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    Genomic context

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    See NPY2R in Genome Data Viewer
    Location:
    chromosome: 15
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 15 NC_051819.1 (53475002..53484515)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 15 NC_006597.4 (53131265..53141184)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 15 NC_049236.1 (53149800..53159345)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 15 NC_049275.1 (52727621..52737421)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 15 NC_049756.1 (52836294..52846610)

    Chromosome 15 - NC_051819.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC111098917 Neighboring gene uncharacterized LOC111098918 Neighboring gene uncharacterized LOC111090108 Neighboring gene dnaJ homolog subfamily C member 21-like

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Suppression of ethanol self-administration by the neuropeptide Y (NPY) Y2 receptor antagonist BIIE0246: evidence for sensitization in rats with a history of dependence. Rimondini R, et al. Neurosci Lett, 2005 Feb 28. PMID 15670655

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. These data confirm that antagonism at central NPY-Y2 receptors selectively suppresses motivation to self-administer ethanol, and indicate that the NPY system is sensitized in animals with a history of dependence.
      Title: Suppression of ethanol self-administration by the neuropeptide Y (NPY) Y2 receptor antagonist BIIE0246: evidence for sensitization in rats with a history of dependence.
    Submit: New GeneRIF Correction

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables neuropeptide Y receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in G protein-coupled receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    neuropeptide Y receptor type 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051819.1 Reference ROS_Cfam_1.0

      Range
      53475002..53484515
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      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038688696.1 → XP_038544624.1  neuropeptide Y receptor type 2

      Conserved Domains (1) summary
      cd15399
      Location:52 → 337
      7tmA_NPY2R; neuropeptide Y receptor type 2, member of the class A family of seven-transmembrane G protein-coupled receptors

    2. XM_038688695.1 → XP_038544623.1  neuropeptide Y receptor type 2

      Conserved Domains (1) summary
      cd15399
      Location:52 → 337
      7tmA_NPY2R; neuropeptide Y receptor type 2, member of the class A family of seven-transmembrane G protein-coupled receptors

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049275.1 Alternate UMICH_Zoey_3.1

      Range
      52727621..52737421
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038496693.1 → XP_038352621.1  neuropeptide Y receptor type 2

      Conserved Domains (1) summary
      cd15399
      Location:52 → 337
      7tmA_NPY2R; neuropeptide Y receptor type 2, member of the class A family of seven-transmembrane G protein-coupled receptors

    2. XM_038496692.1 → XP_038352620.1  neuropeptide Y receptor type 2

      Conserved Domains (1) summary
      cd15399
      Location:52 → 337
      7tmA_NPY2R; neuropeptide Y receptor type 2, member of the class A family of seven-transmembrane G protein-coupled receptors

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049756.1 Alternate UNSW_CanFamBas_1.0

      Range
      52836294..52846610
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038623023.1 → XP_038478951.1  neuropeptide Y receptor type 2

      Conserved Domains (1) summary
      cd15399
      Location:52 → 337
      7tmA_NPY2R; neuropeptide Y receptor type 2, member of the class A family of seven-transmembrane G protein-coupled receptors

    2. XM_038623022.1 → XP_038478950.1  neuropeptide Y receptor type 2

      Conserved Domains (1) summary
      cd15399
      Location:52 → 337
      7tmA_NPY2R; neuropeptide Y receptor type 2, member of the class A family of seven-transmembrane G protein-coupled receptors

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049236.1 Alternate UU_Cfam_GSD_1.0

      Range
      53149800..53159345
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038559086.1 → XP_038415014.1  neuropeptide Y receptor type 2

      Conserved Domains (1) summary
      cd15399
      Location:52 → 337
      7tmA_NPY2R; neuropeptide Y receptor type 2, member of the class A family of seven-transmembrane G protein-coupled receptors

    2. XM_038559085.1 → XP_038415013.1  neuropeptide Y receptor type 2

      Conserved Domains (1) summary
      cd15399
      Location:52 → 337
      7tmA_NPY2R; neuropeptide Y receptor type 2, member of the class A family of seven-transmembrane G protein-coupled receptors

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006597.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      53131265..53141184
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038451982.1 → XP_038307910.1  neuropeptide Y receptor type 2

      Conserved Domains (1) summary
      cd15399
      Location:52 → 337
      7tmA_NPY2R; neuropeptide Y receptor type 2, member of the class A family of seven-transmembrane G protein-coupled receptors

    2. XM_005629373.4 → XP_005629430.3  neuropeptide Y receptor type 2

      Conserved Domains (1) summary
      cd15399
      Location:52 → 337
      7tmA_NPY2R; neuropeptide Y receptor type 2, member of the class A family of seven-transmembrane G protein-coupled receptors
    Nucleotide Protein
    Heading Accession and Version

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