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    LOX lysyl oxidase [ Canis lupus familiaris (dog) ]

    Gene ID: 481478, updated on 5-Mar-2024

    Summary

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    Official Symbol
    LOXprovided by VGNC
    Official Full Name
    lysyl oxidaseprovided by VGNC
    Primary source
    VGNC:VGNC:42737
    See related
    Ensembl:ENSCAFG00845007914
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Orthologs
    human mouse all
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    Genomic context

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    See LOX in Genome Data Viewer
    Location:
    chromosome: 11
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 11 NC_051815.1 (12730282..12744862, complement)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 11 NC_006593.4 (10807698..10821728, complement)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 11 NC_049232.1 (11920314..11934905, complement)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 11 NC_049271.1 (11471714..11486299, complement)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 11 NC_049752.1 (11289217..11303248, complement)

    Chromosome 11 - NC_051815.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC106559531 Neighboring gene ferritin heavy chain-like Neighboring gene serum response factor binding protein 1 Neighboring gene uncharacterized LOC106559462 Neighboring gene uncharacterized LOC111097999 Neighboring gene zinc finger protein 474 Neighboring gene synuclein alpha interacting protein Neighboring gene ribosomal protein L10a pseudogene

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genetic basis of cranial cruciate ligament rupture (CCLR) in dogs. Baird AE, et al. Connect Tissue Res, 2014 Aug. PMID 24684544

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables copper ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein-lysine 6-oxidase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in peptidyl-lysine oxidation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in extracellular space IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    protein-lysine 6-oxidase
    XP_005626496.1
    XP_038345811.1
    XP_038345812.1
    XP_038407872.1
    XP_038407873.1
    XP_038471740.1
    XP_038471741.1
    XP_038537235.1
    XP_038537236.1
    XP_538599.2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051815.1 Reference ROS_Cfam_1.0

      Range
      12730282..12744862 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038681307.1 → XP_038537235.1  protein-lysine 6-oxidase isoform X1

      UniProtKB/TrEMBL
      A0A411DZC1, A0A8C0Q980, A0A8I3N9H6
      Related
      ENSCAFP00845010795.1, ENSCAFT00845013929.1
      Conserved Domains (1) summary
      pfam01186
      Location:206 → 406
      Lysyl_oxidase; Lysyl oxidase

    2. XM_038681308.1 → XP_038537236.1  protein-lysine 6-oxidase isoform X2

      UniProtKB/TrEMBL
      A0A411DZC1, A0A8C0K9G4
      Conserved Domains (1) summary
      pfam01186
      Location:206 → 406
      Lysyl_oxidase; Lysyl oxidase

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049271.1 Alternate UMICH_Zoey_3.1

      Range
      11471714..11486299 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038489883.1 → XP_038345811.1  protein-lysine 6-oxidase isoform X1

      Conserved Domains (1) summary
      pfam01186
      Location:206 → 406
      Lysyl_oxidase; Lysyl oxidase

    2. XM_038489884.1 → XP_038345812.1  protein-lysine 6-oxidase isoform X2

      Conserved Domains (1) summary
      pfam01186
      Location:206 → 406
      Lysyl_oxidase; Lysyl oxidase

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049752.1 Alternate UNSW_CanFamBas_1.0

      Range
      11289217..11303248 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038615812.1 → XP_038471740.1  protein-lysine 6-oxidase isoform X1

      Conserved Domains (1) summary
      pfam01186
      Location:206 → 406
      Lysyl_oxidase; Lysyl oxidase

    2. XM_038615813.1 → XP_038471741.1  protein-lysine 6-oxidase isoform X2

      Conserved Domains (1) summary
      pfam01186
      Location:206 → 406
      Lysyl_oxidase; Lysyl oxidase

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049232.1 Alternate UU_Cfam_GSD_1.0

      Range
      11920314..11934905 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038551944.1 → XP_038407872.1  protein-lysine 6-oxidase isoform X1

      UniProtKB/TrEMBL
      A0A411DZC1, A0A8C0Q980, A0A8I3N9H6
      Conserved Domains (1) summary
      pfam01186
      Location:206 → 406
      Lysyl_oxidase; Lysyl oxidase

    2. XM_038551945.1 → XP_038407873.1  protein-lysine 6-oxidase isoform X2

      UniProtKB/TrEMBL
      A0A411DZC1, A0A8C0K9G4
      Conserved Domains (1) summary
      pfam01186
      Location:206 → 406
      Lysyl_oxidase; Lysyl oxidase

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006593.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      10807698..10821728 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005626439.4 → XP_005626496.1  protein-lysine 6-oxidase isoform X1

      UniProtKB/TrEMBL
      A0A411DZC1, A0A8C0Q980, A0A8I3N9H6
      Conserved Domains (1) summary
      pfam01186
      Location:206 → 406
      Lysyl_oxidase; Lysyl oxidase

    2. XM_538599.6 → XP_538599.2  protein-lysine 6-oxidase isoform X2

      UniProtKB/TrEMBL
      A0A411DZC1, A0A8C0K9G4
      Conserved Domains (1) summary
      pfam01186
      Location:206 → 406
      Lysyl_oxidase; Lysyl oxidase
    Nucleotide Protein
    Heading Accession and Version

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