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    PRDM4 PR/SET domain 4 [ Canis lupus familiaris (dog) ]

    Gene ID: 481291, updated on 17-Aug-2024

    Summary

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    Official Symbol
    PRDM4provided by VGNC
    Official Full Name
    PR/SET domain 4provided by VGNC
    Primary source
    VGNC:VGNC:44949
    See related
    Ensembl:ENSCAFG00845011355
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Orthologs
    human mouse all
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    Genomic context

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    See PRDM4 in Genome Data Viewer
    Location:
    chromosome: 10
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 10 NC_051814.1 (31916430..31944338)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 10 NC_006592.4 (31056699..31084641)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 10 NC_049231.1 (32131601..32159592)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 10 NC_049270.1 (31655923..31683803)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 10 NC_049751.1 (31945006..31972913)

    Chromosome 10 - NC_051814.1Genomic Context describing neighboring genes Neighboring gene U4 spliceosomal RNA Neighboring gene voltage-dependent anion-selective channel protein 2-like Neighboring gene achaete-scute family bHLH transcription factor 4 Neighboring gene uncharacterized LOC119873640 Neighboring gene PWP1 homolog, endonuclein Neighboring gene ankyrin repeat and BTB domain containing 3 Neighboring gene uncharacterized LOC119873641

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables histone deacetylase binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables histone methyltransferase binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cell fate commitment IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    PR domain zinc finger protein 4

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051814.1 Reference ROS_Cfam_1.0

      Range
      31916430..31944338
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038680062.1 → XP_038535990.1  PR domain zinc finger protein 4 isoform X3

      UniProtKB/TrEMBL
      A0A8C0QGN3
      Conserved Domains (5) summary
      sd00017
      Location:550 → 570
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam18445
      Location:365 → 402
      zf_PR_Knuckle; PR zinc knuckle motif
      cd19189
      Location:405 → 544
      PR-SET_PRDM4; PR-SET domain found in PR domain zinc finger protein 4 (PRDM4) and similar proteins
      pfam00096
      Location:548 → 570
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:562 → 585
      zf-H2C2_2; Zinc-finger double domain

    2. XM_038680060.1 → XP_038535988.1  PR domain zinc finger protein 4 isoform X1

      UniProtKB/TrEMBL
      A0A8C0QGN3
      Conserved Domains (4) summary
      sd00017
      Location:627 → 647
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam18445
      Location:365 → 402
      zf_PR_Knuckle; PR zinc knuckle motif
      cd19189
      Location:405 → 544
      PR-SET_PRDM4; PR-SET domain found in PR domain zinc finger protein 4 (PRDM4) and similar proteins
      pfam13465
      Location:639 → 664
      zf-H2C2_2; Zinc-finger double domain

    3. XM_038680061.1 → XP_038535989.1  PR domain zinc finger protein 4 isoform X2

      UniProtKB/TrEMBL
      A0A8C0JWQ6, A0A8C0M9U0, A0A8C0QGN3, A0A8I3NKI9
      Related
      ENSCAFP00845015777.1, ENSCAFT00845020127.1
      Conserved Domains (4) summary
      sd00017
      Location:620 → 640
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam18445
      Location:365 → 402
      zf_PR_Knuckle; PR zinc knuckle motif
      cd19189
      Location:405 → 537
      PR-SET_PRDM4; PR-SET domain found in PR domain zinc finger protein 4 (PRDM4) and similar proteins
      pfam13465
      Location:632 → 657
      zf-H2C2_2; Zinc-finger double domain

    RNA

    1. XR_005433478.1 RNA Sequence

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049270.1 Alternate UMICH_Zoey_3.1

      Range
      31655923..31683803
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038488810.1 → XP_038344738.1  PR domain zinc finger protein 4 isoform X3

      Conserved Domains (5) summary
      sd00017
      Location:550 → 570
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam18445
      Location:365 → 402
      zf_PR_Knuckle; PR zinc knuckle motif
      cd19189
      Location:405 → 544
      PR-SET_PRDM4; PR-SET domain found in PR domain zinc finger protein 4 (PRDM4) and similar proteins
      pfam00096
      Location:548 → 570
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:562 → 585
      zf-H2C2_2; Zinc-finger double domain

    2. XM_038488808.1 → XP_038344736.1  PR domain zinc finger protein 4 isoform X1

    3. XM_038488809.1 → XP_038344737.1  PR domain zinc finger protein 4 isoform X2

    RNA

    1. XR_005331995.1 RNA Sequence

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049751.1 Alternate UNSW_CanFamBas_1.0

      Range
      31945006..31972913
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038614689.1 → XP_038470617.1  PR domain zinc finger protein 4 isoform X3

      Conserved Domains (5) summary
      sd00017
      Location:550 → 570
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam18445
      Location:365 → 402
      zf_PR_Knuckle; PR zinc knuckle motif
      cd19189
      Location:405 → 544
      PR-SET_PRDM4; PR-SET domain found in PR domain zinc finger protein 4 (PRDM4) and similar proteins
      pfam00096
      Location:548 → 570
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:562 → 585
      zf-H2C2_2; Zinc-finger double domain

    2. XM_038614687.1 → XP_038470615.1  PR domain zinc finger protein 4 isoform X1

      Conserved Domains (4) summary
      sd00017
      Location:627 → 647
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam18445
      Location:365 → 402
      zf_PR_Knuckle; PR zinc knuckle motif
      cd19189
      Location:405 → 544
      PR-SET_PRDM4; PR-SET domain found in PR domain zinc finger protein 4 (PRDM4) and similar proteins
      pfam13465
      Location:639 → 664
      zf-H2C2_2; Zinc-finger double domain

    3. XM_038614688.1 → XP_038470616.1  PR domain zinc finger protein 4 isoform X2

      Conserved Domains (4) summary
      sd00017
      Location:620 → 640
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam18445
      Location:365 → 402
      zf_PR_Knuckle; PR zinc knuckle motif
      cd19189
      Location:405 → 537
      PR-SET_PRDM4; PR-SET domain found in PR domain zinc finger protein 4 (PRDM4) and similar proteins
      pfam13465
      Location:632 → 657
      zf-H2C2_2; Zinc-finger double domain

    RNA

    1. XR_005400112.1 RNA Sequence

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049231.1 Alternate UU_Cfam_GSD_1.0

      Range
      32131601..32159592
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038550767.1 → XP_038406695.1  PR domain zinc finger protein 4 isoform X3

      UniProtKB/TrEMBL
      A0A8C0QGN3
      Conserved Domains (5) summary
      sd00017
      Location:550 → 570
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam18445
      Location:365 → 402
      zf_PR_Knuckle; PR zinc knuckle motif
      cd19189
      Location:405 → 544
      PR-SET_PRDM4; PR-SET domain found in PR domain zinc finger protein 4 (PRDM4) and similar proteins
      pfam00096
      Location:548 → 570
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:562 → 585
      zf-H2C2_2; Zinc-finger double domain

    2. XM_038550764.1 → XP_038406692.1  PR domain zinc finger protein 4 isoform X1

      UniProtKB/TrEMBL
      A0A8C0QGN3
      Conserved Domains (4) summary
      sd00017
      Location:627 → 647
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam18445
      Location:365 → 402
      zf_PR_Knuckle; PR zinc knuckle motif
      cd19189
      Location:405 → 544
      PR-SET_PRDM4; PR-SET domain found in PR domain zinc finger protein 4 (PRDM4) and similar proteins
      pfam13465
      Location:639 → 664
      zf-H2C2_2; Zinc-finger double domain

    3. XM_038550766.1 → XP_038406694.1  PR domain zinc finger protein 4 isoform X2

      UniProtKB/TrEMBL
      A0A8C0JWQ6, A0A8C0M9U0, A0A8C0QGN3, A0A8I3NKI9
      Conserved Domains (4) summary
      sd00017
      Location:620 → 640
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam18445
      Location:365 → 402
      zf_PR_Knuckle; PR zinc knuckle motif
      cd19189
      Location:405 → 537
      PR-SET_PRDM4; PR-SET domain found in PR domain zinc finger protein 4 (PRDM4) and similar proteins
      pfam13465
      Location:632 → 657
      zf-H2C2_2; Zinc-finger double domain

    RNA

    1. XR_005365663.1 RNA Sequence

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006592.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      31056699..31084641
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038642087.1 → XP_038498015.1  PR domain zinc finger protein 4 isoform X3

      UniProtKB/TrEMBL
      A0A8C0QGN3
      Conserved Domains (5) summary
      sd00017
      Location:550 → 570
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam18445
      Location:365 → 402
      zf_PR_Knuckle; PR zinc knuckle motif
      cd19189
      Location:405 → 544
      PR-SET_PRDM4; PR-SET domain found in PR domain zinc finger protein 4 (PRDM4) and similar proteins
      pfam00096
      Location:548 → 570
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:562 → 585
      zf-H2C2_2; Zinc-finger double domain

    2. XM_038642075.1 → XP_038498003.1  PR domain zinc finger protein 4 isoform X1

      UniProtKB/TrEMBL
      A0A8C0QGN3
      Conserved Domains (4) summary
      sd00017
      Location:627 → 647
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam18445
      Location:365 → 402
      zf_PR_Knuckle; PR zinc knuckle motif
      cd19189
      Location:405 → 544
      PR-SET_PRDM4; PR-SET domain found in PR domain zinc finger protein 4 (PRDM4) and similar proteins
      pfam13465
      Location:639 → 664
      zf-H2C2_2; Zinc-finger double domain

    3. XM_038642084.1 → XP_038498012.1  PR domain zinc finger protein 4 isoform X2

      UniProtKB/TrEMBL
      A0A8C0JWQ6, A0A8C0M9U0, A0A8C0QGN3, A0A8I3NKI9
      Conserved Domains (4) summary
      sd00017
      Location:620 → 640
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam18445
      Location:365 → 402
      zf_PR_Knuckle; PR zinc knuckle motif
      cd19189
      Location:405 → 537
      PR-SET_PRDM4; PR-SET domain found in PR domain zinc finger protein 4 (PRDM4) and similar proteins
      pfam13465
      Location:632 → 657
      zf-H2C2_2; Zinc-finger double domain

    RNA

    1. XR_005413951.1 RNA Sequence

    Nucleotide Protein
    Heading Accession and Version

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