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    BECN1 beclin 1 [ Canis lupus familiaris (dog) ]

    Gene ID: 480513, updated on 17-Aug-2024

    Summary

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    Official Symbol
    BECN1provided by VGNC
    Official Full Name
    beclin 1provided by VGNC
    Primary source
    VGNC:VGNC:111361
    See related
    Ensembl:ENSCAFG00845007505
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Orthologs
    human mouse all
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    Genomic context

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    See BECN1 in Genome Data Viewer
    Location:
    chromosome: 9
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 9 NC_051813.1 (20922592..20933221)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 9 NC_006591.4 (19665517..19676150)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 9 NC_049230.1 (20076426..20087053)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 9 NC_049269.1 (19707479..19718113)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 9 NC_049750.1 (19973720..19984352)

    Chromosome 9 - NC_051813.1Genomic Context describing neighboring genes Neighboring gene amine oxidase copper containing 2 Neighboring gene proteasome activator subunit 3 Neighboring gene cyclin N-terminal domain containing 1 Neighboring gene coiled-coil domain containing 56 Neighboring gene WNK lysine deficient protein kinase 4

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Process Evidence Code Pubs
    involved_in autophagosome assembly IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in autophagy IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cellular response to nitrogen starvation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in late endosome to vacuole transport IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in phagophore assembly site IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    part_of phosphatidylinositol 3-kinase complex, class III, type I IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    part_of phosphatidylinositol 3-kinase complex, class III, type II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    Beclin-1; beclin-1
    Names
    beclin 1, autophagy related

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051813.1 Reference ROS_Cfam_1.0

      Range
      20922592..20933221
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038676393.1 → XP_038532321.1  beclin-1 isoform X1

      UniProtKB/TrEMBL
      A0A8C0RAA1, A0A8C0Z385, A0A8I3N683
      Conserved Domains (3) summary
      pfam15285
      Location:128 → 150
      BH3; Beclin-1 BH3 domain, Bcl-2-interacting
      pfam04111
      Location:288 → 466
      APG6; Autophagy protein Apg6
      pfam17675
      Location:156 → 282
      APG6_N; Apg6 coiled-coil region

    2. XM_038676392.1 → XP_038532320.1  beclin-1 isoform X1

      UniProtKB/TrEMBL
      A0A8C0RAA1, A0A8C0Z385, A0A8I3N683
      Related
      ENSCAFP00845010315.1, ENSCAFT00845013287.1
      Conserved Domains (3) summary
      pfam15285
      Location:128 → 150
      BH3; Beclin-1 BH3 domain, Bcl-2-interacting
      pfam04111
      Location:288 → 466
      APG6; Autophagy protein Apg6
      pfam17675
      Location:156 → 282
      APG6_N; Apg6 coiled-coil region

    3. XM_038676394.1 → XP_038532322.1  beclin-1 isoform X2

      UniProtKB/TrEMBL
      A0A8C0KJH3, A0A8C0TAY3, A0A8C0Z385, A0A8I3MVR6
      Related
      ENSCAFP00845010343.1, ENSCAFT00845013332.1
      Conserved Domains (3) summary
      pfam15285
      Location:105 → 127
      BH3; Beclin-1 BH3 domain, Bcl-2-interacting
      pfam04111
      Location:265 → 443
      APG6; Autophagy protein Apg6
      pfam17675
      Location:133 → 259
      APG6_N; Apg6 coiled-coil region

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049269.1 Alternate UMICH_Zoey_3.1

      Range
      19707479..19718113
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038485476.1 → XP_038341404.1  beclin-1 isoform X1

    2. XM_038485475.1 → XP_038341403.1  beclin-1 isoform X1

    3. XM_038485477.1 → XP_038341405.1  beclin-1 isoform X2

      Conserved Domains (3) summary
      pfam15285
      Location:105 → 127
      BH3; Beclin-1 BH3 domain, Bcl-2-interacting
      pfam04111
      Location:265 → 443
      APG6; Autophagy protein Apg6
      pfam17675
      Location:133 → 259
      APG6_N; Apg6 coiled-coil region

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049750.1 Alternate UNSW_CanFamBas_1.0

      Range
      19973720..19984352
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038611207.1 → XP_038467135.1  beclin-1 isoform X1

      Conserved Domains (3) summary
      pfam15285
      Location:128 → 150
      BH3; Beclin-1 BH3 domain, Bcl-2-interacting
      pfam04111
      Location:288 → 466
      APG6; Autophagy protein Apg6
      pfam17675
      Location:156 → 282
      APG6_N; Apg6 coiled-coil region

    2. XM_038611206.1 → XP_038467134.1  beclin-1 isoform X1

      Conserved Domains (3) summary
      pfam15285
      Location:128 → 150
      BH3; Beclin-1 BH3 domain, Bcl-2-interacting
      pfam04111
      Location:288 → 466
      APG6; Autophagy protein Apg6
      pfam17675
      Location:156 → 282
      APG6_N; Apg6 coiled-coil region

    3. XM_038611208.1 → XP_038467136.1  beclin-1 isoform X2

      Conserved Domains (3) summary
      pfam15285
      Location:105 → 127
      BH3; Beclin-1 BH3 domain, Bcl-2-interacting
      pfam04111
      Location:265 → 443
      APG6; Autophagy protein Apg6
      pfam17675
      Location:133 → 259
      APG6_N; Apg6 coiled-coil region

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049230.1 Alternate UU_Cfam_GSD_1.0

      Range
      20076426..20087053
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038547237.1 → XP_038403165.1  beclin-1 isoform X1

      UniProtKB/TrEMBL
      A0A8C0RAA1, A0A8C0Z385, A0A8I3N683
      Conserved Domains (3) summary
      pfam15285
      Location:128 → 150
      BH3; Beclin-1 BH3 domain, Bcl-2-interacting
      pfam04111
      Location:288 → 466
      APG6; Autophagy protein Apg6
      pfam17675
      Location:156 → 282
      APG6_N; Apg6 coiled-coil region

    2. XM_038547238.1 → XP_038403166.1  beclin-1 isoform X2

      UniProtKB/TrEMBL
      A0A8C0KJH3, A0A8C0TAY3, A0A8C0Z385, A0A8I3MVR6
      Conserved Domains (3) summary
      pfam15285
      Location:105 → 127
      BH3; Beclin-1 BH3 domain, Bcl-2-interacting
      pfam04111
      Location:265 → 443
      APG6; Autophagy protein Apg6
      pfam17675
      Location:133 → 259
      APG6_N; Apg6 coiled-coil region

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006591.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      19665517..19676150
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_022422964.2 → XP_022278672.1  beclin-1 isoform X1

      UniProtKB/TrEMBL
      A0A8C0RAA1, A0A8C0Z385, A0A8I3N683
      Conserved Domains (3) summary
      pfam15285
      Location:128 → 150
      BH3; Beclin-1 BH3 domain, Bcl-2-interacting
      pfam04111
      Location:288 → 466
      APG6; Autophagy protein Apg6
      pfam17675
      Location:156 → 282
      APG6_N; Apg6 coiled-coil region

    2. XM_005624442.4 → XP_005624499.1  beclin-1 isoform X1

      UniProtKB/TrEMBL
      A0A8C0RAA1, A0A8C0Z385, A0A8I3N683
      Conserved Domains (3) summary
      pfam15285
      Location:128 → 150
      BH3; Beclin-1 BH3 domain, Bcl-2-interacting
      pfam04111
      Location:288 → 466
      APG6; Autophagy protein Apg6
      pfam17675
      Location:156 → 282
      APG6_N; Apg6 coiled-coil region

    3. XM_537634.7 → XP_537634.3  beclin-1 isoform X2

      UniProtKB/TrEMBL
      A0A8C0KJH3, A0A8C0TAY3, A0A8C0Z385, A0A8I3MVR6
      Conserved Domains (3) summary
      pfam15285
      Location:105 → 127
      BH3; Beclin-1 BH3 domain, Bcl-2-interacting
      pfam04111
      Location:265 → 443
      APG6; Autophagy protein Apg6
      pfam17675
      Location:133 → 259
      APG6_N; Apg6 coiled-coil region
    Nucleotide Protein
    Heading Accession and Version

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