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    OTUB2 OTU deubiquitinase, ubiquitin aldehyde binding 2 [ Canis lupus familiaris (dog) ]

    Gene ID: 480420, updated on 17-Aug-2024

    Summary

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    Official Symbol
    OTUB2provided by VGNC
    Official Full Name
    OTU deubiquitinase, ubiquitin aldehyde binding 2provided by VGNC
    Primary source
    VGNC:VGNC:44183
    See related
    Ensembl:ENSCAFG00845002573
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Orthologs
    human mouse all
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    Genomic context

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    See OTUB2 in Genome Data Viewer
    Location:
    chromosome: 8
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 8 NC_051812.1 (63365723..63384970)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 8 NC_006590.4 (62671269..62687875)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 8 NC_049229.1 (63424888..63441523)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 8 NC_049268.1 (63043280..63059899)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 8 NC_049749.1 (63094695..63111321)

    Chromosome 8 - NC_051812.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC102152467 Neighboring gene coiled-coil domain containing 197 Neighboring gene DEAD-box helicase 24 Neighboring gene uncharacterized LOC119872921

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables cysteine-type deubiquitinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables ubiquitin binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in negative regulation of double-strand break repair IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein K48-linked deubiquitination IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    ubiquitin thioesterase OTUB2
    Names
    OTU domain, ubiquitin aldehyde binding 2
    XP_005623818.1
    XP_022278051.1
    XP_038340035.1
    XP_038340036.1
    XP_038401545.1
    XP_038401546.1
    XP_038465641.1
    XP_038465642.1
    XP_038530452.1
    XP_038530453.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051812.1 Reference ROS_Cfam_1.0

      Range
      63365723..63384970
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038674524.1 → XP_038530452.1  ubiquitin thioesterase OTUB2 isoform X1

      Conserved Domains (1) summary
      pfam10275
      Location:35 → 262
      Peptidase_C65; Peptidase C65 Otubain

    2. XM_038674525.1 → XP_038530453.1  ubiquitin thioesterase OTUB2 isoform X2

      UniProtKB/TrEMBL
      A0A8I3MLD1, A0A8P0TMU6
      Related
      ENSCAFP00845003648.1, ENSCAFT00845004566.1
      Conserved Domains (1) summary
      pfam10275
      Location:1 → 229
      Peptidase_C65; Peptidase C65 Otubain

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049268.1 Alternate UMICH_Zoey_3.1

      Range
      63043280..63059899
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038484107.1 → XP_038340035.1  ubiquitin thioesterase OTUB2 isoform X1

      Conserved Domains (1) summary
      pfam10275
      Location:35 → 262
      Peptidase_C65; Peptidase C65 Otubain

    2. XM_038484108.1 → XP_038340036.1  ubiquitin thioesterase OTUB2 isoform X2

      Conserved Domains (1) summary
      pfam10275
      Location:1 → 229
      Peptidase_C65; Peptidase C65 Otubain

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049749.1 Alternate UNSW_CanFamBas_1.0

      Range
      63094695..63111321
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038609713.1 → XP_038465641.1  ubiquitin thioesterase OTUB2 isoform X1

      Conserved Domains (1) summary
      pfam10275
      Location:35 → 262
      Peptidase_C65; Peptidase C65 Otubain

    2. XM_038609714.1 → XP_038465642.1  ubiquitin thioesterase OTUB2 isoform X2

      Conserved Domains (1) summary
      pfam10275
      Location:1 → 229
      Peptidase_C65; Peptidase C65 Otubain

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049229.1 Alternate UU_Cfam_GSD_1.0

      Range
      63424888..63441523
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038545617.1 → XP_038401545.1  ubiquitin thioesterase OTUB2 isoform X1

      Conserved Domains (1) summary
      pfam10275
      Location:35 → 262
      Peptidase_C65; Peptidase C65 Otubain

    2. XM_038545618.1 → XP_038401546.1  ubiquitin thioesterase OTUB2 isoform X2

      UniProtKB/TrEMBL
      A0A8I3MLD1, A0A8P0TMU6
      Conserved Domains (1) summary
      pfam10275
      Location:1 → 229
      Peptidase_C65; Peptidase C65 Otubain

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006590.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      62671269..62687875
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_022422343.2 → XP_022278051.1  ubiquitin thioesterase OTUB2 isoform X1

      Conserved Domains (1) summary
      pfam10275
      Location:35 → 262
      Peptidase_C65; Peptidase C65 Otubain

    2. XM_005623761.3 → XP_005623818.1  ubiquitin thioesterase OTUB2 isoform X2

      UniProtKB/TrEMBL
      A0A8I3MLD1, A0A8P0TMU6
      Conserved Domains (1) summary
      pfam10275
      Location:1 → 229
      Peptidase_C65; Peptidase C65 Otubain
    Nucleotide Protein
    Heading Accession and Version

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