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    EIF2S1 eukaryotic translation initiation factor 2 subunit alpha [ Canis lupus familiaris (dog) ]

    Gene ID: 480361, updated on 17-Aug-2024

    Summary

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    Official Symbol
    EIF2S1provided by VGNC
    Official Full Name
    eukaryotic translation initiation factor 2 subunit alphaprovided by VGNC
    Primary source
    VGNC:VGNC:40266
    See related
    Ensembl:ENSCAFG00845003308
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Orthologs
    human mouse all
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    Genomic context

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    See EIF2S1 in Genome Data Viewer
    Location:
    chromosome: 8
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 8 NC_051812.1 (41581554..41598447)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 8 NC_006590.4 (41045920..41062790)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 8 NC_049229.1 (41632932..41649922)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 8 NC_049268.1 (41200418..41217284)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 8 NC_049749.1 (41273999..41290966)

    Chromosome 8 - NC_051812.1Genomic Context describing neighboring genes Neighboring gene protein associated with LIN7 1, MAGUK p55 family member Neighboring gene uncharacterized LOC106559172 Neighboring gene ATPase H+ transporting V1 subunit D Neighboring gene pleckstrin 2 Neighboring gene uncharacterized LOC111097223

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables ribosome binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables translation initiation factor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of eukaryotic 48S preinitiation complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    part_of eukaryotic translation initiation factor 2 complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    part_of eukaryotic translation initiation factor 2B complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    part_of multi-eIF complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    eukaryotic translation initiation factor 2 subunit 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051812.1 Reference ROS_Cfam_1.0

      Range
      41581554..41598447
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038673911.1 → XP_038529839.1  eukaryotic translation initiation factor 2 subunit 1

      UniProtKB/TrEMBL
      A0A8C0K002, A0A8C0NPW2, A0A8C0RLY3, A0A8I3MV19
      Related
      ENSCAFP00845004658.1, ENSCAFT00845005861.1
      Conserved Domains (1) summary
      PTZ00248
      Location:4 → 315
      PTZ00248; eukaryotic translation initiation factor 2 subunit 1; Provisional

    2. XM_038673910.1 → XP_038529838.1  eukaryotic translation initiation factor 2 subunit 1

      UniProtKB/TrEMBL
      A0A8C0K002, A0A8C0NPW2, A0A8C0RLY3, A0A8I3MV19
      Conserved Domains (1) summary
      PTZ00248
      Location:4 → 315
      PTZ00248; eukaryotic translation initiation factor 2 subunit 1; Provisional

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049268.1 Alternate UMICH_Zoey_3.1

      Range
      41200418..41217284
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038483526.1 → XP_038339454.1  eukaryotic translation initiation factor 2 subunit 1

      Conserved Domains (1) summary
      PTZ00248
      Location:4 → 315
      PTZ00248; eukaryotic translation initiation factor 2 subunit 1; Provisional

    2. XM_038483525.1 → XP_038339453.1  eukaryotic translation initiation factor 2 subunit 1

      Conserved Domains (1) summary
      PTZ00248
      Location:4 → 315
      PTZ00248; eukaryotic translation initiation factor 2 subunit 1; Provisional

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049749.1 Alternate UNSW_CanFamBas_1.0

      Range
      41273999..41290966
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038609106.1 → XP_038465034.1  eukaryotic translation initiation factor 2 subunit 1

      Conserved Domains (1) summary
      PTZ00248
      Location:4 → 315
      PTZ00248; eukaryotic translation initiation factor 2 subunit 1; Provisional

    2. XM_038609105.1 → XP_038465033.1  eukaryotic translation initiation factor 2 subunit 1

      Conserved Domains (1) summary
      PTZ00248
      Location:4 → 315
      PTZ00248; eukaryotic translation initiation factor 2 subunit 1; Provisional

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049229.1 Alternate UU_Cfam_GSD_1.0

      Range
      41632932..41649922
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038544993.1 → XP_038400921.1  eukaryotic translation initiation factor 2 subunit 1

      UniProtKB/TrEMBL
      A0A8C0K002, A0A8C0NPW2, A0A8C0RLY3, A0A8I3MV19
      Conserved Domains (1) summary
      PTZ00248
      Location:4 → 315
      PTZ00248; eukaryotic translation initiation factor 2 subunit 1; Provisional

    2. XM_038544992.1 → XP_038400920.1  eukaryotic translation initiation factor 2 subunit 1

      UniProtKB/TrEMBL
      A0A8C0K002, A0A8C0NPW2, A0A8C0RLY3, A0A8I3MV19
      Conserved Domains (1) summary
      PTZ00248
      Location:4 → 315
      PTZ00248; eukaryotic translation initiation factor 2 subunit 1; Provisional

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006590.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      41045920..41062790
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005623535.4 → XP_005623592.1  eukaryotic translation initiation factor 2 subunit 1

      See identical proteins and their annotated locations for XP_005623592.1

      UniProtKB/TrEMBL
      A0A8C0K002, A0A8C0NPW2, A0A8C0RLY3, A0A8I3MV19
      Conserved Domains (1) summary
      PTZ00248
      Location:4 → 315
      PTZ00248; eukaryotic translation initiation factor 2 subunit 1; Provisional

    2. XM_038589523.1 → XP_038445451.1  eukaryotic translation initiation factor 2 subunit 1

      UniProtKB/TrEMBL
      A0A8C0K002, A0A8C0NPW2, A0A8C0RLY3, A0A8I3MV19
      Conserved Domains (1) summary
      PTZ00248
      Location:4 → 315
      PTZ00248; eukaryotic translation initiation factor 2 subunit 1; Provisional
    Nucleotide Protein
    Heading Accession and Version

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