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    PSMA6 proteasome 20S subunit alpha 6 [ Canis lupus familiaris (dog) ]

    Gene ID: 480290, updated on 17-Aug-2024

    Summary

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    Official Symbol
    PSMA6provided by VGNC
    Official Full Name
    proteasome 20S subunit alpha 6provided by VGNC
    Primary source
    VGNC:VGNC:45091
    See related
    Ensembl:ENSCAFG00845001929
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Orthologs
    human mouse all
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    Genomic context

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    See PSMA6 in Genome Data Viewer
    Location:
    chromosome: 8
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 8 NC_051812.1 (14116970..14144066)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 8 NC_006590.4 (13807535..13834775)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 8 NC_049229.1 (14173313..14200558)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 8 NC_049268.1 (13818618..13845898)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 8 NC_049749.1 (13883420..13910936)

    Chromosome 8 - NC_051812.1Genomic Context describing neighboring genes Neighboring gene protein phosphatase 2 regulatory subunit B''gamma Neighboring gene protein only RNase P catalytic subunit Neighboring gene uncharacterized LOC111096992 Neighboring gene dnaJ homolog subfamily A member 1-like Neighboring gene uncharacterized LOC111096993 Neighboring gene uncharacterized LOC111096994

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Process Evidence Code Pubs
    involved_in ubiquitin-dependent protein catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    part_of proteasome core complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    part_of proteasome core complex, alpha-subunit complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    proteasome subunit alpha type-6
    Names
    proteasome (prosome, macropain) subunit, alpha type, 6
    proteasome subunit alpha 6
    XP_005623383.1
    XP_038338965.1
    XP_038338966.1
    XP_038400418.1
    XP_038400419.1
    XP_038464533.1
    XP_038464534.1
    XP_038529350.1
    XP_038529351.1
    XP_537412.2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051812.1 Reference ROS_Cfam_1.0

      Range
      14116970..14144066
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038673423.1 → XP_038529351.1  proteasome subunit alpha type-6 isoform X2

      UniProtKB/TrEMBL
      A0A8C0LEB1, A0A8C0N3Q9, A0A8C0RDG3, A0A8I3MJ89, A0A8I3PJW0
      Related
      ENSCAFP00845002685.1, ENSCAFT00845003382.1
      Conserved Domains (1) summary
      cd03754
      Location:7 → 201
      proteasome_alpha_type_6; The 20S proteasome, multisubunit proteolytic complex, is the central enzyme of nonlysosomal protein degradation in both the cytosol and nucleus. It is composed of 28 subunits arranged as four homoheptameric rings that stack on top of one another forming ...

    2. XM_038673422.1 → XP_038529350.1  proteasome subunit alpha type-6 isoform X1

      UniProtKB/TrEMBL
      A0A8C0LBT3, A0A8C0LEB1, A0A8C0N3Q9, A0A8C0SR54, A0A8I3N0P1, A0A8I3PJW0
      Related
      ENSCAFP00845002811.1, ENSCAFT00845003540.1
      Conserved Domains (1) summary
      cd03754
      Location:8 → 220
      proteasome_alpha_type_6; The 20S proteasome, multisubunit proteolytic complex, is the central enzyme of nonlysosomal protein degradation in both the cytosol and nucleus. It is composed of 28 subunits arranged as four homoheptameric rings that stack on top of one another forming ...

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049268.1 Alternate UMICH_Zoey_3.1

      Range
      13818618..13845898
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038483038.1 → XP_038338966.1  proteasome subunit alpha type-6 isoform X2

      Conserved Domains (1) summary
      cd03754
      Location:7 → 201
      proteasome_alpha_type_6; The 20S proteasome, multisubunit proteolytic complex, is the central enzyme of nonlysosomal protein degradation in both the cytosol and nucleus. It is composed of 28 subunits arranged as four homoheptameric rings that stack on top of one another forming ...

    2. XM_038483037.1 → XP_038338965.1  proteasome subunit alpha type-6 isoform X1

      Conserved Domains (1) summary
      cd03754
      Location:8 → 220
      proteasome_alpha_type_6; The 20S proteasome, multisubunit proteolytic complex, is the central enzyme of nonlysosomal protein degradation in both the cytosol and nucleus. It is composed of 28 subunits arranged as four homoheptameric rings that stack on top of one another forming ...

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049749.1 Alternate UNSW_CanFamBas_1.0

      Range
      13883420..13910936
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038608606.1 → XP_038464534.1  proteasome subunit alpha type-6 isoform X2

      Conserved Domains (1) summary
      cd03754
      Location:7 → 201
      proteasome_alpha_type_6; The 20S proteasome, multisubunit proteolytic complex, is the central enzyme of nonlysosomal protein degradation in both the cytosol and nucleus. It is composed of 28 subunits arranged as four homoheptameric rings that stack on top of one another forming ...

    2. XM_038608605.1 → XP_038464533.1  proteasome subunit alpha type-6 isoform X1

      Conserved Domains (1) summary
      cd03754
      Location:8 → 220
      proteasome_alpha_type_6; The 20S proteasome, multisubunit proteolytic complex, is the central enzyme of nonlysosomal protein degradation in both the cytosol and nucleus. It is composed of 28 subunits arranged as four homoheptameric rings that stack on top of one another forming ...

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049229.1 Alternate UU_Cfam_GSD_1.0

      Range
      14173313..14200558
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038544491.1 → XP_038400419.1  proteasome subunit alpha type-6 isoform X2

      UniProtKB/TrEMBL
      A0A8C0LEB1, A0A8C0N3Q9, A0A8C0RDG3, A0A8I3MJ89, A0A8I3PJW0
      Conserved Domains (1) summary
      cd03754
      Location:7 → 201
      proteasome_alpha_type_6; The 20S proteasome, multisubunit proteolytic complex, is the central enzyme of nonlysosomal protein degradation in both the cytosol and nucleus. It is composed of 28 subunits arranged as four homoheptameric rings that stack on top of one another forming ...

    2. XM_038544490.1 → XP_038400418.1  proteasome subunit alpha type-6 isoform X1

      UniProtKB/TrEMBL
      A0A8C0LBT3, A0A8C0LEB1, A0A8C0N3Q9, A0A8C0SR54, A0A8I3N0P1, A0A8I3PJW0
      Conserved Domains (1) summary
      cd03754
      Location:8 → 220
      proteasome_alpha_type_6; The 20S proteasome, multisubunit proteolytic complex, is the central enzyme of nonlysosomal protein degradation in both the cytosol and nucleus. It is composed of 28 subunits arranged as four homoheptameric rings that stack on top of one another forming ...

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006590.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      13807535..13834775
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005623326.4 → XP_005623383.1  proteasome subunit alpha type-6 isoform X2

      See identical proteins and their annotated locations for XP_005623383.1

      UniProtKB/TrEMBL
      A0A8C0LEB1, A0A8C0N3Q9, A0A8C0RDG3, A0A8I3MJ89, A0A8I3PJW0
      Conserved Domains (1) summary
      cd03754
      Location:7 → 201
      proteasome_alpha_type_6; The 20S proteasome, multisubunit proteolytic complex, is the central enzyme of nonlysosomal protein degradation in both the cytosol and nucleus. It is composed of 28 subunits arranged as four homoheptameric rings that stack on top of one another forming ...

    2. XM_537412.7 → XP_537412.2  proteasome subunit alpha type-6 isoform X1

      See identical proteins and their annotated locations for XP_537412.2

      UniProtKB/TrEMBL
      A0A8C0LBT3, A0A8C0LEB1, A0A8C0N3Q9, A0A8C0SR54, A0A8I3N0P1, A0A8I3PJW0
      Conserved Domains (1) summary
      cd03754
      Location:8 → 220
      proteasome_alpha_type_6; The 20S proteasome, multisubunit proteolytic complex, is the central enzyme of nonlysosomal protein degradation in both the cytosol and nucleus. It is composed of 28 subunits arranged as four homoheptameric rings that stack on top of one another forming ...
    Nucleotide Protein
    Heading Accession and Version

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