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    FH fumarate hydratase [ Canis lupus familiaris (dog) ]

    Gene ID: 480092, updated on 17-Aug-2024

    Summary

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    Official Symbol
    FHprovided by VGNC
    Official Full Name
    fumarate hydrataseprovided by VGNC
    Primary source
    VGNC:VGNC:40867
    See related
    Ensembl:ENSCAFG00845004348
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: 7
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 7 NC_051811.1 (32726854..32753856, complement)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 7 NC_006589.4 (32378016..32404992, complement)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 7 NC_049228.1 (32834235..32861236, complement)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 7 NC_049267.1 (32562040..32588973, complement)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 7 NC_049748.1 (32586108..32613094, complement)

    Chromosome 7 - NC_051811.1Genomic Context describing neighboring genes Neighboring gene regulator of G protein signaling 7 Neighboring gene uncharacterized LOC119872538 Neighboring gene ribosome biogenesis protein NSA2 homolog Neighboring gene uncharacterized LOC106559037 Neighboring gene kynurenine 3-monooxygenase Neighboring gene opsin 3 Neighboring gene CHM like Rab escort protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables fumarate hydratase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in fumarate metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in malate metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in tricarboxylic acid cycle IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    part_of tricarboxylic acid cycle heteromeric enzyme complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    fumarate hydratase, mitochondrial
    XP_038337246.1
    XP_038398603.1
    XP_038462750.1
    XP_038527428.1
    XP_537215.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051811.1 Reference ROS_Cfam_1.0

      Range
      32726854..32753856 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038671500.1 → XP_038527428.1  fumarate hydratase, mitochondrial

      UniProtKB/TrEMBL
      A0A8C0LBE5, A0A8C0NZZ1, A0A8C0Q033, A0A8I3MXC4
      Related
      ENSCAFP00845006196.1, ENSCAFT00845007825.1
      Conserved Domains (1) summary
      PRK00485
      Location:47 → 508
      fumC; fumarate hydratase; Reviewed

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049267.1 Alternate UMICH_Zoey_3.1

      Range
      32562040..32588973 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038481318.1 → XP_038337246.1  fumarate hydratase, mitochondrial

      Conserved Domains (1) summary
      PRK00485
      Location:47 → 508
      fumC; fumarate hydratase; Reviewed

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049748.1 Alternate UNSW_CanFamBas_1.0

      Range
      32586108..32613094 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038606822.1 → XP_038462750.1  fumarate hydratase, mitochondrial

      Conserved Domains (1) summary
      PRK00485
      Location:47 → 508
      fumC; fumarate hydratase; Reviewed

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049228.1 Alternate UU_Cfam_GSD_1.0

      Range
      32834235..32861236 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038542675.1 → XP_038398603.1  fumarate hydratase, mitochondrial

      UniProtKB/TrEMBL
      A0A8C0LBE5, A0A8C0NZZ1, A0A8C0Q033, A0A8I3MXC4
      Conserved Domains (1) summary
      PRK00485
      Location:47 → 508
      fumC; fumarate hydratase; Reviewed

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006589.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      32378016..32404992 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_537215.6 → XP_537215.1  fumarate hydratase, mitochondrial

      UniProtKB/TrEMBL
      A0A8C0LBE5, A0A8C0NZZ1, A0A8C0Q033, A0A8I3MXC4
      Conserved Domains (1) summary
      PRK00485
      Location:47 → 508
      fumC; fumarate hydratase; Reviewed
    Nucleotide Protein
    Heading Accession and Version

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