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    UNC5B unc-5 netrin receptor B [ Canis lupus familiaris (dog) ]

    Gene ID: 479239, updated on 17-Aug-2024

    Summary

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    Official Symbol
    UNC5Bprovided by VGNC
    Official Full Name
    unc-5 netrin receptor Bprovided by VGNC
    Primary source
    VGNC:VGNC:48140
    See related
    Ensembl:ENSCAFG00845004449
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: 4
    Exon count:
    17
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 4 NC_051808.1 (22280582..22358557)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 4 NC_006586.4 (22139026..22219691)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 4 NC_049225.1 (22736647..22817352)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 4 NC_049264.1 (22178248..22258859)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 4 NC_049745.1 (22383898..22464744)

    Chromosome 4 - NC_051808.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC111095475 Neighboring gene uncharacterized LOC119871626 Neighboring gene solute carrier family 29 member 3 Neighboring gene cadherin related 23 Neighboring gene U2 spliceosomal RNA

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables netrin receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in anterior/posterior axon guidance IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in netrin-activated signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    netrin receptor UNC5B; LOW QUALITY PROTEIN: netrin receptor UNC5B
    Names
    unc-5 homolog B

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051808.1 Reference ROS_Cfam_1.0

      Range
      22280582..22358557
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038662836.1 → XP_038518764.1  netrin receptor UNC5B isoform X2

      UniProtKB/TrEMBL
      A0A8C0LPB0, A0A8C0N5Y9, A0A8I3MS99
      Related
      ENSCAFP00845006284.1, ENSCAFT00845007984.1
      Conserved Domains (6) summary
      smart00218
      Location:541 → 644
      ZU5; Domain present in ZO-1 and Unc5-like netrin receptors
      cd08802
      Location:858 → 941
      Death_UNC5B; Death domain found in Uncoordinated-5B
      smart00209
      Location:249 → 300
      TSP1; Thrombospondin type 1 repeats
      pfam17217
      Location:691 → 830
      UPA; UPA domain
      cd00096
      Location:161 → 165
      Ig; Ig strand A' [structural motif]
      cl11960
      Location:157 → 243
      Ig; Immunoglobulin domain

    2. XM_038662837.1 → XP_038518765.1  netrin receptor UNC5B isoform X1

      UniProtKB/TrEMBL
      A0A8C0LPB0, A0A8C0PT81, A0A8I3RTJ0
      Related
      ENSCAFP00845006302.1, ENSCAFT00845008009.1
      Conserved Domains (6) summary
      smart00218
      Location:530 → 633
      ZU5; Domain present in ZO-1 and Unc5-like netrin receptors
      cd08802
      Location:847 → 930
      Death_UNC5B; Death domain found in Uncoordinated-5B
      smart00209
      Location:249 → 300
      TSP1; Thrombospondin type 1 repeats
      pfam17217
      Location:680 → 819
      UPA; UPA domain
      cd00096
      Location:161 → 165
      Ig; Ig strand A' [structural motif]
      cl11960
      Location:157 → 243
      Ig; Immunoglobulin domain

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049264.1 Alternate UMICH_Zoey_3.1

      Range
      22178248..22258859
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038473189.1 → XP_038329117.1  netrin receptor UNC5B isoform X2

      Conserved Domains (6) summary
      smart00218
      Location:541 → 644
      ZU5; Domain present in ZO-1 and Unc5-like netrin receptors
      cd08802
      Location:858 → 941
      Death_UNC5B; Death domain found in Uncoordinated-5B
      smart00209
      Location:249 → 300
      TSP1; Thrombospondin type 1 repeats
      pfam17217
      Location:691 → 830
      UPA; UPA domain
      cd00096
      Location:161 → 165
      Ig; Ig strand A' [structural motif]
      cl11960
      Location:157 → 243
      Ig; Immunoglobulin domain

    2. XM_038473190.1 → XP_038329118.1  netrin receptor UNC5B isoform X1

      Conserved Domains (6) summary
      smart00218
      Location:530 → 633
      ZU5; Domain present in ZO-1 and Unc5-like netrin receptors
      cd08802
      Location:847 → 930
      Death_UNC5B; Death domain found in Uncoordinated-5B
      smart00209
      Location:249 → 300
      TSP1; Thrombospondin type 1 repeats
      pfam17217
      Location:680 → 819
      UPA; UPA domain
      cd00096
      Location:161 → 165
      Ig; Ig strand A' [structural motif]
      cl11960
      Location:157 → 243
      Ig; Immunoglobulin domain

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049745.1 Alternate UNSW_CanFamBas_1.0

      Range
      22383898..22464744
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038598566.1 → XP_038454494.1  LOW QUALITY PROTEIN: netrin receptor UNC5B isoform X2

      Conserved Domains (6) summary
      smart00218
      Location:541 → 644
      ZU5; Domain present in ZO-1 and Unc5-like netrin receptors
      cd08802
      Location:858 → 941
      Death_UNC5B; Death domain found in Uncoordinated-5B
      smart00209
      Location:249 → 300
      TSP1; Thrombospondin type 1 repeats
      pfam17217
      Location:691 → 830
      UPA; UPA domain
      cd00096
      Location:161 → 165
      Ig; Ig strand A' [structural motif]
      cl11960
      Location:157 → 243
      Ig; Immunoglobulin domain

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049225.1 Alternate UU_Cfam_GSD_1.0

      Range
      22736647..22817352
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038534250.1 → XP_038390178.1  netrin receptor UNC5B isoform X2

      UniProtKB/TrEMBL
      A0A8C0LPB0

    2. XM_038534251.1 → XP_038390179.1  netrin receptor UNC5B isoform X1

      UniProtKB/TrEMBL
      A0A8C0LPB0

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006586.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      22139026..22219691
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_845335.6 → XP_850428.2  netrin receptor UNC5B isoform X2

      UniProtKB/TrEMBL
      A0A8C0LPB0, A0A8C0N5Y9, A0A8I3MS99
      Conserved Domains (6) summary
      smart00218
      Location:541 → 644
      ZU5; Domain present in ZO-1 and Unc5-like netrin receptors
      cd08802
      Location:858 → 941
      Death_UNC5B; Death domain found in Uncoordinated-5B
      smart00209
      Location:249 → 300
      TSP1; Thrombospondin type 1 repeats
      pfam17217
      Location:691 → 830
      UPA; UPA domain
      cd00096
      Location:161 → 165
      Ig; Ig strand A' [structural motif]
      cl11960
      Location:157 → 243
      Ig; Immunoglobulin domain

    2. XM_003638992.4 → XP_003639040.2  netrin receptor UNC5B isoform X1

      UniProtKB/TrEMBL
      A0A8C0LPB0, A0A8C0PT81, A0A8I3RTJ0
      Conserved Domains (6) summary
      smart00218
      Location:530 → 633
      ZU5; Domain present in ZO-1 and Unc5-like netrin receptors
      cd08802
      Location:847 → 930
      Death_UNC5B; Death domain found in Uncoordinated-5B
      smart00209
      Location:249 → 300
      TSP1; Thrombospondin type 1 repeats
      pfam17217
      Location:680 → 819
      UPA; UPA domain
      cd00096
      Location:161 → 165
      Ig; Ig strand A' [structural motif]
      cl11960
      Location:157 → 243
      Ig; Immunoglobulin domain
    Nucleotide Protein
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