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    IDH2 isocitrate dehydrogenase (NADP(+)) 2 [ Canis lupus familiaris (dog) ]

    Gene ID: 479043, updated on 17-Aug-2024

    Summary

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    Official Symbol
    IDH2provided by VGNC
    Official Full Name
    isocitrate dehydrogenase (NADP(+)) 2provided by VGNC
    Primary source
    VGNC:VGNC:53183
    See related
    Ensembl:ENSCAFG00845000909
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Orthologs
    human mouse all
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    Genomic context

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    See IDH2 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 3 NC_051807.1 (53486432..53502992, complement)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 3 NC_006585.4 (55708523..55724976, complement)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 3 NC_049224.1 (53558279..53574816, complement)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 3 NC_049263.1 (53006922..53023434, complement)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 3 NC_049744.1 (53217752..53234294, complement)

    Chromosome 3 - NC_051807.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC111095225 Neighboring gene actin related protein 2/3 complex inhibitor Neighboring gene zinc finger protein 710 Neighboring gene uncharacterized LOC111095226 Neighboring gene semaphorin 4B Neighboring gene GDP-D-glucose phosphorylase 1 Neighboring gene calcium and integrin binding 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Functional alteration of canine isocitrate dehydrogenase 2 (IDH2) via an R174K mutation. Kawakami S, et al. J Vet Med Sci, 2018 Jan 27. PMID 29162772, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables NAD binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables isocitrate dehydrogenase (NADP+) activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables magnesium ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in isocitrate metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    isocitrate dehydrogenase [NADP], mitochondrial; LOW QUALITY PROTEIN: isocitrate dehydrogenase [NADP], mitochondrial
    Names
    isocitrate dehydrogenase (NADP(+)) 2, mitochondrial
    XP_038327851.1
    XP_038331210.1
    XP_038388781.1
    XP_038453104.1
    XP_038517286.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051807.1 Reference ROS_Cfam_1.0

      Range
      53486432..53502992 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038661358.1 → XP_038517286.1  isocitrate dehydrogenase [NADP], mitochondrial

      UniProtKB/TrEMBL
      A0A2Z5XAD4, A0A8C0R241, A0A8P0NE04
      Related
      ENSCAFP00845001268.1, ENSCAFT00845001600.1
      Conserved Domains (1) summary
      PTZ00435
      Location:41 → 453
      PTZ00435; isocitrate dehydrogenase; Provisional

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049263.1 Alternate UMICH_Zoey_3.1

      Range
      53006922..53023434 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038471923.1 → XP_038327851.1  isocitrate dehydrogenase [NADP], mitochondrial

      Conserved Domains (1) summary
      PTZ00435
      Location:41 → 453
      PTZ00435; isocitrate dehydrogenase; Provisional

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049744.1 Alternate UNSW_CanFamBas_1.0

      Range
      53217752..53234294 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038597176.1 → XP_038453104.1  isocitrate dehydrogenase [NADP], mitochondrial

      Conserved Domains (1) summary
      PTZ00435
      Location:41 → 453
      PTZ00435; isocitrate dehydrogenase; Provisional

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049224.1 Alternate UU_Cfam_GSD_1.0

      Range
      53558279..53574816 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038532853.1 → XP_038388781.1  isocitrate dehydrogenase [NADP], mitochondrial

      UniProtKB/TrEMBL
      A0A2Z5XAD4, A0A8C0R241, A0A8P0NE04
      Conserved Domains (1) summary
      PTZ00435
      Location:41 → 453
      PTZ00435; isocitrate dehydrogenase; Provisional

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006585.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      55708523..55724976 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038475282.1 → XP_038331210.1  LOW QUALITY PROTEIN: isocitrate dehydrogenase [NADP], mitochondrial

      UniProtKB/TrEMBL
      A0A8P0NE04
      Conserved Domains (1) summary
      PTZ00435
      Location:41 → 453
      PTZ00435; isocitrate dehydrogenase; Provisional
    Nucleotide Protein
    Heading Accession and Version

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