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    RXRG retinoid X receptor gamma [ Canis lupus familiaris (dog) ]

    Gene ID: 478989, updated on 17-Aug-2024

    Summary

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    Official Symbol
    RXRGprovided by VGNC
    Official Full Name
    retinoid X receptor gammaprovided by VGNC
    Primary source
    VGNC:VGNC:45819
    See related
    Ensembl:ENSCAFG00845024833
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Orthologs
    human mouse all
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    Genomic context

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    See RXRG in Genome Data Viewer
    Location:
    chromosome: 38
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 38 NC_051842.1 (17947065..17992337)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 38 NC_006620.4 (17922970..17968200)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 38 NC_049259.1 (18565728..18610954)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 38 NC_049298.1 (17919625..17964835)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 38 NC_049779.1 (18271342..18316575)

    Chromosome 38 - NC_051842.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC119868056 Neighboring gene uncharacterized LOC102152982 Neighboring gene leucine rich repeat containing 52 Neighboring gene uncharacterized LOC119868085 Neighboring gene uncharacterized LOC102153440 Neighboring gene LIM homeobox transcription factor 1 alpha

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Comparison of the expression patterns of newly identified zebrafish retinoic acid and retinoid X receptors. Waxman JS, et al. Dev Dyn, 2007 Feb. PMID 17195188
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables nuclear receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables nuclear steroid receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables retinoic acid-responsive element binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in anatomical structure development IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cell differentiation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in response to retinoic acid IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in retinoic acid receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of RNA polymerase II transcription regulator complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    retinoic acid receptor RXR-gamma

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051842.1 Reference ROS_Cfam_1.0

      Range
      17947065..17992337
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038448544.1 → XP_038304472.1  retinoic acid receptor RXR-gamma isoform X3

      UniProtKB/TrEMBL
      A0A8C0JMH8, A0A8C0PBD5, A0A8C0Z0Z0, A0A8I3PIS2
      Related
      ENSCAFP00845034329.1, ENSCAFT00845043809.1
      Conserved Domains (3) summary
      cd06943
      Location:233 → 441
      NR_LBD_RXR_like; The ligand binding domain of the retinoid X receptor and Ultraspiracle, members of nuclear receptor superfamily
      cd06956
      Location:137 → 213
      NR_DBD_RXR; DNA-binding domain of retinoid X receptor (RXR) is composed of two C4-type zinc fingers
      pfam11825
      Location:25 → 133
      Nuc_recep-AF1; Nuclear/hormone receptor activator site AF-1

    2. XM_038448542.1 → XP_038304470.1  retinoic acid receptor RXR-gamma isoform X1

      UniProtKB/TrEMBL
      A0A8I3PJP1, A0A8I3PNM7
      Conserved Domains (3) summary
      cd06943
      Location:274 → 482
      NR_LBD_RXR_like; The ligand binding domain of the retinoid X receptor and Ultraspiracle, members of nuclear receptor superfamily
      cd06956
      Location:178 → 254
      NR_DBD_RXR; DNA-binding domain of retinoid X receptor (RXR) is composed of two C4-type zinc fingers
      pfam11825
      Location:66 → 174
      Nuc_recep-AF1; Nuclear/hormone receptor activator site AF-1

    3. XM_038448541.1 → XP_038304469.1  retinoic acid receptor RXR-gamma isoform X1

      UniProtKB/TrEMBL
      A0A8I3PJP1, A0A8I3PNM7
      Related
      ENSCAFP00845034504.1, ENSCAFT00845044032.1
      Conserved Domains (3) summary
      cd06943
      Location:274 → 482
      NR_LBD_RXR_like; The ligand binding domain of the retinoid X receptor and Ultraspiracle, members of nuclear receptor superfamily
      cd06956
      Location:178 → 254
      NR_DBD_RXR; DNA-binding domain of retinoid X receptor (RXR) is composed of two C4-type zinc fingers
      pfam11825
      Location:66 → 174
      Nuc_recep-AF1; Nuclear/hormone receptor activator site AF-1

    4. XM_038448543.1 → XP_038304471.1  retinoic acid receptor RXR-gamma isoform X2

      UniProtKB/TrEMBL
      A0A8I3PNM7
      Related
      ENSCAFP00845034591.1, ENSCAFT00845044145.1
      Conserved Domains (3) summary
      cd06943
      Location:246 → 454
      NR_LBD_RXR_like; The ligand binding domain of the retinoid X receptor and Ultraspiracle, members of nuclear receptor superfamily
      cd06956
      Location:150 → 226
      NR_DBD_RXR; DNA-binding domain of retinoid X receptor (RXR) is composed of two C4-type zinc fingers
      pfam11825
      Location:38 → 146
      Nuc_recep-AF1; Nuclear/hormone receptor activator site AF-1

    5. XM_038448546.1 → XP_038304474.1  retinoic acid receptor RXR-gamma isoform X4

      Conserved Domains (2) summary
      cd06943
      Location:110 → 318
      NR_LBD_RXR_like; The ligand binding domain of the retinoid X receptor and Ultraspiracle, members of nuclear receptor superfamily
      cd06956
      Location:14 → 90
      NR_DBD_RXR; DNA-binding domain of retinoid X receptor (RXR) is composed of two C4-type zinc fingers

    6. XM_038448545.1 → XP_038304473.1  retinoic acid receptor RXR-gamma isoform X4

      Conserved Domains (2) summary
      cd06943
      Location:110 → 318
      NR_LBD_RXR_like; The ligand binding domain of the retinoid X receptor and Ultraspiracle, members of nuclear receptor superfamily
      cd06956
      Location:14 → 90
      NR_DBD_RXR; DNA-binding domain of retinoid X receptor (RXR) is composed of two C4-type zinc fingers

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049298.1 Alternate UMICH_Zoey_3.1

      Range
      17919625..17964835
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038522432.1 → XP_038378360.1  retinoic acid receptor RXR-gamma isoform X3

      Conserved Domains (3) summary
      cd06943
      Location:233 → 441
      NR_LBD_RXR_like; The ligand binding domain of the retinoid X receptor and Ultraspiracle, members of nuclear receptor superfamily
      cd06956
      Location:137 → 213
      NR_DBD_RXR; DNA-binding domain of retinoid X receptor (RXR) is composed of two C4-type zinc fingers
      pfam11825
      Location:25 → 133
      Nuc_recep-AF1; Nuclear/hormone receptor activator site AF-1

    2. XM_038522430.1 → XP_038378358.1  retinoic acid receptor RXR-gamma isoform X1

      Conserved Domains (3) summary
      cd06943
      Location:274 → 482
      NR_LBD_RXR_like; The ligand binding domain of the retinoid X receptor and Ultraspiracle, members of nuclear receptor superfamily
      cd06956
      Location:178 → 254
      NR_DBD_RXR; DNA-binding domain of retinoid X receptor (RXR) is composed of two C4-type zinc fingers
      pfam11825
      Location:66 → 174
      Nuc_recep-AF1; Nuclear/hormone receptor activator site AF-1

    3. XM_038522429.1 → XP_038378357.1  retinoic acid receptor RXR-gamma isoform X1

      Conserved Domains (3) summary
      cd06943
      Location:274 → 482
      NR_LBD_RXR_like; The ligand binding domain of the retinoid X receptor and Ultraspiracle, members of nuclear receptor superfamily
      cd06956
      Location:178 → 254
      NR_DBD_RXR; DNA-binding domain of retinoid X receptor (RXR) is composed of two C4-type zinc fingers
      pfam11825
      Location:66 → 174
      Nuc_recep-AF1; Nuclear/hormone receptor activator site AF-1

    4. XM_038522431.1 → XP_038378359.1  retinoic acid receptor RXR-gamma isoform X2

      Conserved Domains (3) summary
      cd06943
      Location:246 → 454
      NR_LBD_RXR_like; The ligand binding domain of the retinoid X receptor and Ultraspiracle, members of nuclear receptor superfamily
      cd06956
      Location:150 → 226
      NR_DBD_RXR; DNA-binding domain of retinoid X receptor (RXR) is composed of two C4-type zinc fingers
      pfam11825
      Location:38 → 146
      Nuc_recep-AF1; Nuclear/hormone receptor activator site AF-1

    5. XM_038522434.1 → XP_038378362.1  retinoic acid receptor RXR-gamma isoform X4

      Conserved Domains (2) summary
      cd06943
      Location:110 → 318
      NR_LBD_RXR_like; The ligand binding domain of the retinoid X receptor and Ultraspiracle, members of nuclear receptor superfamily
      cd06956
      Location:14 → 90
      NR_DBD_RXR; DNA-binding domain of retinoid X receptor (RXR) is composed of two C4-type zinc fingers

    6. XM_038522433.1 → XP_038378361.1  retinoic acid receptor RXR-gamma isoform X4

      Conserved Domains (2) summary
      cd06943
      Location:110 → 318
      NR_LBD_RXR_like; The ligand binding domain of the retinoid X receptor and Ultraspiracle, members of nuclear receptor superfamily
      cd06956
      Location:14 → 90
      NR_DBD_RXR; DNA-binding domain of retinoid X receptor (RXR) is composed of two C4-type zinc fingers

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049779.1 Alternate UNSW_CanFamBas_1.0

      Range
      18271342..18316575
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038650637.1 → XP_038506565.1  retinoic acid receptor RXR-gamma isoform X3

      Conserved Domains (3) summary
      cd06943
      Location:233 → 441
      NR_LBD_RXR_like; The ligand binding domain of the retinoid X receptor and Ultraspiracle, members of nuclear receptor superfamily
      cd06956
      Location:137 → 213
      NR_DBD_RXR; DNA-binding domain of retinoid X receptor (RXR) is composed of two C4-type zinc fingers
      pfam11825
      Location:25 → 133
      Nuc_recep-AF1; Nuclear/hormone receptor activator site AF-1

    2. XM_038650635.1 → XP_038506563.1  retinoic acid receptor RXR-gamma isoform X1

      Conserved Domains (3) summary
      cd06943
      Location:274 → 482
      NR_LBD_RXR_like; The ligand binding domain of the retinoid X receptor and Ultraspiracle, members of nuclear receptor superfamily
      cd06956
      Location:178 → 254
      NR_DBD_RXR; DNA-binding domain of retinoid X receptor (RXR) is composed of two C4-type zinc fingers
      pfam11825
      Location:66 → 174
      Nuc_recep-AF1; Nuclear/hormone receptor activator site AF-1

    3. XM_038650634.1 → XP_038506562.1  retinoic acid receptor RXR-gamma isoform X1

      Conserved Domains (3) summary
      cd06943
      Location:274 → 482
      NR_LBD_RXR_like; The ligand binding domain of the retinoid X receptor and Ultraspiracle, members of nuclear receptor superfamily
      cd06956
      Location:178 → 254
      NR_DBD_RXR; DNA-binding domain of retinoid X receptor (RXR) is composed of two C4-type zinc fingers
      pfam11825
      Location:66 → 174
      Nuc_recep-AF1; Nuclear/hormone receptor activator site AF-1

    4. XM_038650636.1 → XP_038506564.1  retinoic acid receptor RXR-gamma isoform X2

      Conserved Domains (3) summary
      cd06943
      Location:246 → 454
      NR_LBD_RXR_like; The ligand binding domain of the retinoid X receptor and Ultraspiracle, members of nuclear receptor superfamily
      cd06956
      Location:150 → 226
      NR_DBD_RXR; DNA-binding domain of retinoid X receptor (RXR) is composed of two C4-type zinc fingers
      pfam11825
      Location:38 → 146
      Nuc_recep-AF1; Nuclear/hormone receptor activator site AF-1

    5. XM_038650639.1 → XP_038506567.1  retinoic acid receptor RXR-gamma isoform X4

      Conserved Domains (2) summary
      cd06943
      Location:110 → 318
      NR_LBD_RXR_like; The ligand binding domain of the retinoid X receptor and Ultraspiracle, members of nuclear receptor superfamily
      cd06956
      Location:14 → 90
      NR_DBD_RXR; DNA-binding domain of retinoid X receptor (RXR) is composed of two C4-type zinc fingers

    6. XM_038650638.1 → XP_038506566.1  retinoic acid receptor RXR-gamma isoform X4

      Conserved Domains (2) summary
      cd06943
      Location:110 → 318
      NR_LBD_RXR_like; The ligand binding domain of the retinoid X receptor and Ultraspiracle, members of nuclear receptor superfamily
      cd06956
      Location:14 → 90
      NR_DBD_RXR; DNA-binding domain of retinoid X receptor (RXR) is composed of two C4-type zinc fingers

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049259.1 Alternate UU_Cfam_GSD_1.0

      Range
      18565728..18610954
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038586224.1 → XP_038442152.1  retinoic acid receptor RXR-gamma isoform X3

      UniProtKB/TrEMBL
      A0A8C0JMH8, A0A8C0PBD5, A0A8C0Z0Z0, A0A8I3PIS2
      Conserved Domains (3) summary
      cd06943
      Location:233 → 441
      NR_LBD_RXR_like; The ligand binding domain of the retinoid X receptor and Ultraspiracle, members of nuclear receptor superfamily
      cd06956
      Location:137 → 213
      NR_DBD_RXR; DNA-binding domain of retinoid X receptor (RXR) is composed of two C4-type zinc fingers
      pfam11825
      Location:25 → 133
      Nuc_recep-AF1; Nuclear/hormone receptor activator site AF-1

    2. XM_038586222.1 → XP_038442150.1  retinoic acid receptor RXR-gamma isoform X1

      UniProtKB/TrEMBL
      A0A8I3PJP1, A0A8I3PNM7
      Conserved Domains (3) summary
      cd06943
      Location:274 → 482
      NR_LBD_RXR_like; The ligand binding domain of the retinoid X receptor and Ultraspiracle, members of nuclear receptor superfamily
      cd06956
      Location:178 → 254
      NR_DBD_RXR; DNA-binding domain of retinoid X receptor (RXR) is composed of two C4-type zinc fingers
      pfam11825
      Location:66 → 174
      Nuc_recep-AF1; Nuclear/hormone receptor activator site AF-1

    3. XM_038586221.1 → XP_038442149.1  retinoic acid receptor RXR-gamma isoform X1

      UniProtKB/TrEMBL
      A0A8I3PJP1, A0A8I3PNM7
      Conserved Domains (3) summary
      cd06943
      Location:274 → 482
      NR_LBD_RXR_like; The ligand binding domain of the retinoid X receptor and Ultraspiracle, members of nuclear receptor superfamily
      cd06956
      Location:178 → 254
      NR_DBD_RXR; DNA-binding domain of retinoid X receptor (RXR) is composed of two C4-type zinc fingers
      pfam11825
      Location:66 → 174
      Nuc_recep-AF1; Nuclear/hormone receptor activator site AF-1

    4. XM_038586223.1 → XP_038442151.1  retinoic acid receptor RXR-gamma isoform X2

      UniProtKB/TrEMBL
      A0A8I3PNM7
      Conserved Domains (3) summary
      cd06943
      Location:246 → 454
      NR_LBD_RXR_like; The ligand binding domain of the retinoid X receptor and Ultraspiracle, members of nuclear receptor superfamily
      cd06956
      Location:150 → 226
      NR_DBD_RXR; DNA-binding domain of retinoid X receptor (RXR) is composed of two C4-type zinc fingers
      pfam11825
      Location:38 → 146
      Nuc_recep-AF1; Nuclear/hormone receptor activator site AF-1

    5. XM_038586226.1 → XP_038442154.1  retinoic acid receptor RXR-gamma isoform X4

      Conserved Domains (2) summary
      cd06943
      Location:110 → 318
      NR_LBD_RXR_like; The ligand binding domain of the retinoid X receptor and Ultraspiracle, members of nuclear receptor superfamily
      cd06956
      Location:14 → 90
      NR_DBD_RXR; DNA-binding domain of retinoid X receptor (RXR) is composed of two C4-type zinc fingers

    6. XM_038586225.1 → XP_038442153.1  retinoic acid receptor RXR-gamma isoform X4

      Conserved Domains (2) summary
      cd06943
      Location:110 → 318
      NR_LBD_RXR_like; The ligand binding domain of the retinoid X receptor and Ultraspiracle, members of nuclear receptor superfamily
      cd06956
      Location:14 → 90
      NR_DBD_RXR; DNA-binding domain of retinoid X receptor (RXR) is composed of two C4-type zinc fingers

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006620.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      17922970..17968200
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_014111278.3 → XP_013966753.1  retinoic acid receptor RXR-gamma isoform X3

      UniProtKB/TrEMBL
      A0A8C0JMH8, A0A8C0PBD5, A0A8C0Z0Z0, A0A8I3PIS2
      Conserved Domains (3) summary
      cd06943
      Location:233 → 441
      NR_LBD_RXR_like; The ligand binding domain of the retinoid X receptor and Ultraspiracle, members of nuclear receptor superfamily
      cd06956
      Location:137 → 213
      NR_DBD_RXR; DNA-binding domain of retinoid X receptor (RXR) is composed of two C4-type zinc fingers
      pfam11825
      Location:25 → 133
      Nuc_recep-AF1; Nuclear/hormone receptor activator site AF-1

    2. XM_038464167.1 → XP_038320095.1  retinoic acid receptor RXR-gamma isoform X1

      UniProtKB/TrEMBL
      A0A8C0T1Q9, A0A8I3PNM7, A0A8P0PBJ6
      Conserved Domains (3) summary
      cd06943
      Location:274 → 482
      NR_LBD_RXR_like; The ligand binding domain of the retinoid X receptor and Ultraspiracle, members of nuclear receptor superfamily
      cd06956
      Location:178 → 254
      NR_DBD_RXR; DNA-binding domain of retinoid X receptor (RXR) is composed of two C4-type zinc fingers
      pfam11825
      Location:66 → 174
      Nuc_recep-AF1; Nuclear/hormone receptor activator site AF-1

    3. XM_005640843.3 → XP_005640900.1  retinoic acid receptor RXR-gamma isoform X1

      UniProtKB/TrEMBL
      A0A8C0T1Q9, A0A8I3PNM7, A0A8P0PBJ6
      Conserved Domains (3) summary
      cd06943
      Location:274 → 482
      NR_LBD_RXR_like; The ligand binding domain of the retinoid X receptor and Ultraspiracle, members of nuclear receptor superfamily
      cd06956
      Location:178 → 254
      NR_DBD_RXR; DNA-binding domain of retinoid X receptor (RXR) is composed of two C4-type zinc fingers
      pfam11825
      Location:66 → 174
      Nuc_recep-AF1; Nuclear/hormone receptor activator site AF-1

    4. XM_014111277.2 → XP_013966752.1  retinoic acid receptor RXR-gamma isoform X2

      UniProtKB/TrEMBL
      A0A8I3PNM7
      Conserved Domains (3) summary
      cd06943
      Location:246 → 454
      NR_LBD_RXR_like; The ligand binding domain of the retinoid X receptor and Ultraspiracle, members of nuclear receptor superfamily
      cd06956
      Location:150 → 226
      NR_DBD_RXR; DNA-binding domain of retinoid X receptor (RXR) is composed of two C4-type zinc fingers
      pfam11825
      Location:38 → 146
      Nuc_recep-AF1; Nuclear/hormone receptor activator site AF-1

    5. XM_014111280.2 → XP_013966755.1  retinoic acid receptor RXR-gamma isoform X4

      Conserved Domains (2) summary
      cd06943
      Location:110 → 318
      NR_LBD_RXR_like; The ligand binding domain of the retinoid X receptor and Ultraspiracle, members of nuclear receptor superfamily
      cd06956
      Location:14 → 90
      NR_DBD_RXR; DNA-binding domain of retinoid X receptor (RXR) is composed of two C4-type zinc fingers

    6. XM_014111279.3 → XP_013966754.1  retinoic acid receptor RXR-gamma isoform X4

      Conserved Domains (2) summary
      cd06943
      Location:110 → 318
      NR_LBD_RXR_like; The ligand binding domain of the retinoid X receptor and Ultraspiracle, members of nuclear receptor superfamily
      cd06956
      Location:14 → 90
      NR_DBD_RXR; DNA-binding domain of retinoid X receptor (RXR) is composed of two C4-type zinc fingers
    Nucleotide Protein
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