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    MYO1B myosin IB [ Canis lupus familiaris (dog) ]

    Gene ID: 478846, updated on 17-Aug-2024

    Summary

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    Official Symbol
    MYO1Bprovided by VGNC
    Official Full Name
    myosin IBprovided by VGNC
    Primary source
    VGNC:VGNC:43561
    See related
    Ensembl:ENSCAFG00845019502
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Orthologs
    human mouse all
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    Genomic context

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    See MYO1B in Genome Data Viewer
    Location:
    chromosome: 37
    Exon count:
    33
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 37 NC_051841.1 (1632808..1808623)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 37 NC_006619.4 (2693497..2869182)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 37 NC_049258.1 (1638672..1814273)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 37 NC_049297.1 (1642176..1819468)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 37 NC_049778.1 (1610548..1786134)

    Chromosome 37 - NC_051841.1Genomic Context describing neighboring genes Neighboring gene signal transducer and activator of transcription 4 Neighboring gene uncharacterized LOC119867891 Neighboring gene uncharacterized LOC111094431 Neighboring gene uncharacterized LOC111094373

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables actin filament binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables microfilament motor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in actin filament organization IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in vesicle transport along actin filament IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in actin cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in brush border IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in microvillus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    part_of myosin complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in vesicle IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    myosin-Ib; unconventional myosin-Ib

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051841.1 Reference ROS_Cfam_1.0

      Range
      1632808..1808623
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038447433.1 → XP_038303361.1  unconventional myosin-Ib isoform X1

      UniProtKB/TrEMBL
      A0A8C0JX95, A0A8C0SRE8, A0A8I3PFN0, A0A8I3S1E3, A0A8P0NC41
      Related
      ENSCAFP00845027290.1, ENSCAFT00845034840.1
      Conserved Domains (3) summary
      smart00015
      Location:749 → 771
      IQ; Calmodulin-binding motif
      cd01378
      Location:29 → 688
      MYSc_Myo1; class I myosin, motor domain
      pfam06017
      Location:941 → 1118
      Myosin_TH1; Unconventional myosin tail, actin- and lipid-binding

    2. XM_038447432.1 → XP_038303360.1  unconventional myosin-Ib isoform X1

      UniProtKB/TrEMBL
      A0A8C0JX95, A0A8C0SRE8, A0A8I3PFN0, A0A8I3S1E3, A0A8P0NC41
      Related
      ENSCAFP00845027494.1, ENSCAFT00845035124.1
      Conserved Domains (3) summary
      smart00015
      Location:749 → 771
      IQ; Calmodulin-binding motif
      cd01378
      Location:29 → 688
      MYSc_Myo1; class I myosin, motor domain
      pfam06017
      Location:941 → 1118
      Myosin_TH1; Unconventional myosin tail, actin- and lipid-binding

    3. XM_038447435.1 → XP_038303363.1  unconventional myosin-Ib isoform X2

      UniProtKB/TrEMBL
      A0A8C0JWN2, A0A8C0SSZ1, A0A8C0SV28, A0A8I3P9E4
      Related
      ENSCAFP00845026949.1, ENSCAFT00845034412.1
      Conserved Domains (3) summary
      smart00015
      Location:749 → 771
      IQ; Calmodulin-binding motif
      cd01378
      Location:29 → 688
      MYSc_Myo1; class I myosin, motor domain
      pfam06017
      Location:912 → 1089
      Myosin_TH1; Unconventional myosin tail, actin- and lipid-binding

    4. XM_038447436.1 → XP_038303364.1  unconventional myosin-Ib isoform X3

      UniProtKB/TrEMBL
      A0A8C0JY87, A0A8C0SSU8, A0A8C0SSZ1, A0A8I3S1I2
      Related
      ENSCAFP00845027722.1, ENSCAFT00845035414.1
      Conserved Domains (3) summary
      smart00015
      Location:749 → 771
      IQ; Calmodulin-binding motif
      cd01378
      Location:29 → 688
      MYSc_Myo1; class I myosin, motor domain
      pfam06017
      Location:883 → 1060
      Myosin_TH1; Unconventional myosin tail, actin- and lipid-binding

    5. XM_038447434.1 → XP_038303362.1  unconventional myosin-Ib isoform X1

      UniProtKB/TrEMBL
      A0A8C0JX95, A0A8C0SRE8, A0A8I3PFN0, A0A8I3S1E3, A0A8P0NC41
      Conserved Domains (3) summary
      smart00015
      Location:749 → 771
      IQ; Calmodulin-binding motif
      cd01378
      Location:29 → 688
      MYSc_Myo1; class I myosin, motor domain
      pfam06017
      Location:941 → 1118
      Myosin_TH1; Unconventional myosin tail, actin- and lipid-binding

    6. XM_038447437.1 → XP_038303365.1  unconventional myosin-Ib isoform X4

      UniProtKB/TrEMBL
      A0A8C0RNB7
      Conserved Domains (3) summary
      smart00015
      Location:669 → 691
      IQ; Calmodulin-binding motif
      cd01378
      Location:4 → 608
      MYSc_Myo1; class I myosin, motor domain
      pfam06017
      Location:861 → 1038
      Myosin_TH1; Unconventional myosin tail, actin- and lipid-binding

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049297.1 Alternate UMICH_Zoey_3.1

      Range
      1642176..1819468
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038521497.1 → XP_038377425.1  unconventional myosin-Ib isoform X1

      Conserved Domains (3) summary
      smart00015
      Location:749 → 771
      IQ; Calmodulin-binding motif
      cd01378
      Location:29 → 688
      MYSc_Myo1; class I myosin, motor domain
      pfam06017
      Location:941 → 1118
      Myosin_TH1; Unconventional myosin tail, actin- and lipid-binding

    2. XM_038521496.1 → XP_038377424.1  unconventional myosin-Ib isoform X1

      Conserved Domains (3) summary
      smart00015
      Location:749 → 771
      IQ; Calmodulin-binding motif
      cd01378
      Location:29 → 688
      MYSc_Myo1; class I myosin, motor domain
      pfam06017
      Location:941 → 1118
      Myosin_TH1; Unconventional myosin tail, actin- and lipid-binding

    3. XM_038521500.1 → XP_038377428.1  unconventional myosin-Ib isoform X2

      Conserved Domains (3) summary
      smart00015
      Location:749 → 771
      IQ; Calmodulin-binding motif
      cd01378
      Location:29 → 688
      MYSc_Myo1; class I myosin, motor domain
      pfam06017
      Location:912 → 1089
      Myosin_TH1; Unconventional myosin tail, actin- and lipid-binding

    4. XM_038521501.1 → XP_038377429.1  unconventional myosin-Ib isoform X3

      Conserved Domains (3) summary
      smart00015
      Location:749 → 771
      IQ; Calmodulin-binding motif
      cd01378
      Location:29 → 688
      MYSc_Myo1; class I myosin, motor domain
      pfam06017
      Location:883 → 1060
      Myosin_TH1; Unconventional myosin tail, actin- and lipid-binding

    5. XM_038521498.1 → XP_038377426.1  unconventional myosin-Ib isoform X1

      Conserved Domains (3) summary
      smart00015
      Location:749 → 771
      IQ; Calmodulin-binding motif
      cd01378
      Location:29 → 688
      MYSc_Myo1; class I myosin, motor domain
      pfam06017
      Location:941 → 1118
      Myosin_TH1; Unconventional myosin tail, actin- and lipid-binding

    6. XM_038521502.1 → XP_038377430.1  unconventional myosin-Ib isoform X4

      Conserved Domains (3) summary
      smart00015
      Location:669 → 691
      IQ; Calmodulin-binding motif
      cd01378
      Location:4 → 608
      MYSc_Myo1; class I myosin, motor domain
      pfam06017
      Location:861 → 1038
      Myosin_TH1; Unconventional myosin tail, actin- and lipid-binding

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049778.1 Alternate UNSW_CanFamBas_1.0

      Range
      1610548..1786134
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038649606.1 → XP_038505534.1  unconventional myosin-Ib isoform X1

    2. XM_038649605.1 → XP_038505533.1  unconventional myosin-Ib isoform X1

    3. XM_038649608.1 → XP_038505536.1  unconventional myosin-Ib isoform X2

    4. XM_038649609.1 → XP_038505537.1  unconventional myosin-Ib isoform X3

    5. XM_038649607.1 → XP_038505535.1  unconventional myosin-Ib isoform X1

    6. XM_038649610.1 → XP_038505538.1  unconventional myosin-Ib isoform X4

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049258.1 Alternate UU_Cfam_GSD_1.0

      Range
      1638672..1814273
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038585198.1 → XP_038441126.1  unconventional myosin-Ib isoform X1

      UniProtKB/TrEMBL
      A0A8C0JX95, A0A8C0SRE8, A0A8I3PFN0, A0A8I3S1E3, A0A8P0NC41
      Conserved Domains (3) summary
      smart00015
      Location:749 → 771
      IQ; Calmodulin-binding motif
      cd01378
      Location:29 → 688
      MYSc_Myo1; class I myosin, motor domain
      pfam06017
      Location:941 → 1118
      Myosin_TH1; Unconventional myosin tail, actin- and lipid-binding

    2. XM_038585197.1 → XP_038441125.1  unconventional myosin-Ib isoform X1

      UniProtKB/TrEMBL
      A0A8C0JX95, A0A8C0SRE8, A0A8I3PFN0, A0A8I3S1E3, A0A8P0NC41
      Conserved Domains (3) summary
      smart00015
      Location:749 → 771
      IQ; Calmodulin-binding motif
      cd01378
      Location:29 → 688
      MYSc_Myo1; class I myosin, motor domain
      pfam06017
      Location:941 → 1118
      Myosin_TH1; Unconventional myosin tail, actin- and lipid-binding

    3. XM_038585200.1 → XP_038441128.1  unconventional myosin-Ib isoform X2

      UniProtKB/TrEMBL
      A0A8C0JWN2, A0A8C0SSZ1, A0A8C0SV28, A0A8I3P9E4
      Conserved Domains (3) summary
      smart00015
      Location:749 → 771
      IQ; Calmodulin-binding motif
      cd01378
      Location:29 → 688
      MYSc_Myo1; class I myosin, motor domain
      pfam06017
      Location:912 → 1089
      Myosin_TH1; Unconventional myosin tail, actin- and lipid-binding

    4. XM_038585201.1 → XP_038441129.1  unconventional myosin-Ib isoform X3

      UniProtKB/TrEMBL
      A0A8C0JY87, A0A8C0SSU8, A0A8C0SSZ1, A0A8I3S1I2
      Conserved Domains (3) summary
      smart00015
      Location:749 → 771
      IQ; Calmodulin-binding motif
      cd01378
      Location:29 → 688
      MYSc_Myo1; class I myosin, motor domain
      pfam06017
      Location:883 → 1060
      Myosin_TH1; Unconventional myosin tail, actin- and lipid-binding

    5. XM_038585199.1 → XP_038441127.1  unconventional myosin-Ib isoform X1

      UniProtKB/TrEMBL
      A0A8C0JX95, A0A8C0SRE8, A0A8I3PFN0, A0A8I3S1E3, A0A8P0NC41
      Conserved Domains (3) summary
      smart00015
      Location:749 → 771
      IQ; Calmodulin-binding motif
      cd01378
      Location:29 → 688
      MYSc_Myo1; class I myosin, motor domain
      pfam06017
      Location:941 → 1118
      Myosin_TH1; Unconventional myosin tail, actin- and lipid-binding

    6. XM_038585202.1 → XP_038441130.1  unconventional myosin-Ib isoform X4

      UniProtKB/TrEMBL
      A0A8C0RNB7
      Conserved Domains (3) summary
      smart00015
      Location:669 → 691
      IQ; Calmodulin-binding motif
      cd01378
      Location:4 → 608
      MYSc_Myo1; class I myosin, motor domain
      pfam06017
      Location:861 → 1038
      Myosin_TH1; Unconventional myosin tail, actin- and lipid-binding

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006619.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      2693497..2869182
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038463646.1 → XP_038319574.1  unconventional myosin-Ib isoform X1

      UniProtKB/TrEMBL
      A0A8C0JX95, A0A8C0SRE8, A0A8I3PFN0, A0A8I3S1E3, A0A8P0NC41
      Conserved Domains (3) summary
      smart00015
      Location:749 → 771
      IQ; Calmodulin-binding motif
      cd01378
      Location:29 → 688
      MYSc_Myo1; class I myosin, motor domain
      pfam06017
      Location:941 → 1118
      Myosin_TH1; Unconventional myosin tail, actin- and lipid-binding

    2. XM_038463645.1 → XP_038319573.1  unconventional myosin-Ib isoform X1

      UniProtKB/TrEMBL
      A0A8C0JX95, A0A8C0SRE8, A0A8I3PFN0, A0A8I3S1E3, A0A8P0NC41
      Conserved Domains (3) summary
      smart00015
      Location:749 → 771
      IQ; Calmodulin-binding motif
      cd01378
      Location:29 → 688
      MYSc_Myo1; class I myosin, motor domain
      pfam06017
      Location:941 → 1118
      Myosin_TH1; Unconventional myosin tail, actin- and lipid-binding

    3. XM_038463648.1 → XP_038319576.1  unconventional myosin-Ib isoform X2

      UniProtKB/TrEMBL
      A0A8C0JWN2, A0A8C0SSZ1, A0A8C0SV28, A0A8I3P9E4
      Conserved Domains (3) summary
      smart00015
      Location:749 → 771
      IQ; Calmodulin-binding motif
      cd01378
      Location:29 → 688
      MYSc_Myo1; class I myosin, motor domain
      pfam06017
      Location:912 → 1089
      Myosin_TH1; Unconventional myosin tail, actin- and lipid-binding

    4. XM_038463649.1 → XP_038319577.1  unconventional myosin-Ib isoform X3

      UniProtKB/TrEMBL
      A0A8C0JY87, A0A8C0SSU8, A0A8C0SSZ1, A0A8I3S1I2
      Conserved Domains (3) summary
      smart00015
      Location:749 → 771
      IQ; Calmodulin-binding motif
      cd01378
      Location:29 → 688
      MYSc_Myo1; class I myosin, motor domain
      pfam06017
      Location:883 → 1060
      Myosin_TH1; Unconventional myosin tail, actin- and lipid-binding

    5. XM_038463647.1 → XP_038319575.1  unconventional myosin-Ib isoform X1

      UniProtKB/TrEMBL
      A0A8C0JX95, A0A8C0SRE8, A0A8I3PFN0, A0A8I3S1E3, A0A8P0NC41
      Conserved Domains (3) summary
      smart00015
      Location:749 → 771
      IQ; Calmodulin-binding motif
      cd01378
      Location:29 → 688
      MYSc_Myo1; class I myosin, motor domain
      pfam06017
      Location:941 → 1118
      Myosin_TH1; Unconventional myosin tail, actin- and lipid-binding

    6. XM_038463650.1 → XP_038319578.1  unconventional myosin-Ib isoform X4

      UniProtKB/TrEMBL
      A0A8C0RNB7
      Conserved Domains (3) summary
      smart00015
      Location:669 → 691
      IQ; Calmodulin-binding motif
      cd01378
      Location:4 → 608
      MYSc_Myo1; class I myosin, motor domain
      pfam06017
      Location:861 → 1038
      Myosin_TH1; Unconventional myosin tail, actin- and lipid-binding
    Nucleotide Protein
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