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    SSB small RNA binding exonuclease protection factor La [ Canis lupus familiaris (dog) ]

    Gene ID: 478787, updated on 17-Aug-2024

    Summary

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    Official Symbol
    SSBprovided by VGNC
    Official Full Name
    small RNA binding exonuclease protection factor Laprovided by VGNC
    Primary source
    VGNC:VGNC:58552
    See related
    Ensembl:ENSCAFG00845024004
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Orthologs
    human mouse all
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    Genomic context

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    See SSB in Genome Data Viewer
    Location:
    chromosome: 36
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 36 NC_051840.1 (14584035..14595782)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 36 NC_006618.4 (14477215..14488515)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 36 NC_049257.1 (14770849..14782579)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 36 NC_049296.1 (14667144..14678600)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 36 NC_049777.1 (14659402..14670867)

    Chromosome 36 - NC_051840.1Genomic Context describing neighboring genes Neighboring gene kelch like family member 23 Neighboring gene Ewing sarcoma breakpoint region 1 pseudogene Neighboring gene methyltransferase 5, N6-adenosine Neighboring gene ubiquitin protein ligase E3 component n-recognin 3 Neighboring gene uncharacterized LOC111094278

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in RNA processing IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of translation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasmic stress granule IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    part_of ribonucleoprotein complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    lupus La protein
    Names
    Sjogren syndrome antigen B

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051840.1 Reference ROS_Cfam_1.0

      Range
      14584035..14595782
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038446997.1 → XP_038302925.1  lupus La protein

      UniProtKB/TrEMBL
      A0A8C0MPL8, A0A8C0QUD0, A0A8C0TUD6, A0A8I3PZQ3, A0A8I3S7X5
      Related
      ENSCAFP00845033280.1, ENSCAFT00845042454.1
      Conserved Domains (3) summary
      cd08028
      Location:10 → 91
      LARP_3; La RNA-binding domain of La-related protein 3
      pfam08777
      Location:231 → 334
      RRM_3; RNA binding motif
      cd12291
      Location:112 → 183
      RRM1_La; RNA recognition motif 1 in La autoantigen (La or LARP3) and similar proteins

    2. XM_038446998.1 → XP_038302926.1  lupus La protein

      UniProtKB/TrEMBL
      A0A8C0MPL8, A0A8C0QUD0, A0A8C0TUD6, A0A8I3PZQ3, A0A8I3S7X5
      Conserved Domains (3) summary
      cd08028
      Location:10 → 91
      LARP_3; La RNA-binding domain of La-related protein 3
      pfam08777
      Location:231 → 334
      RRM_3; RNA binding motif
      cd12291
      Location:112 → 183
      RRM1_La; RNA recognition motif 1 in La autoantigen (La or LARP3) and similar proteins

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049296.1 Alternate UMICH_Zoey_3.1

      Range
      14667144..14678600
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038521072.1 → XP_038377000.1  lupus La protein

      Conserved Domains (3) summary
      cd08028
      Location:10 → 91
      LARP_3; La RNA-binding domain of La-related protein 3
      pfam08777
      Location:231 → 334
      RRM_3; RNA binding motif
      cd12291
      Location:112 → 183
      RRM1_La; RNA recognition motif 1 in La autoantigen (La or LARP3) and similar proteins

    2. XM_038521073.1 → XP_038377001.1  lupus La protein

      Conserved Domains (3) summary
      cd08028
      Location:10 → 91
      LARP_3; La RNA-binding domain of La-related protein 3
      pfam08777
      Location:231 → 334
      RRM_3; RNA binding motif
      cd12291
      Location:112 → 183
      RRM1_La; RNA recognition motif 1 in La autoantigen (La or LARP3) and similar proteins

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049777.1 Alternate UNSW_CanFamBas_1.0

      Range
      14659402..14670867
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038649189.1 → XP_038505117.1  lupus La protein

      Conserved Domains (3) summary
      cd08028
      Location:10 → 91
      LARP_3; La RNA-binding domain of La-related protein 3
      pfam08777
      Location:231 → 334
      RRM_3; RNA binding motif
      cd12291
      Location:112 → 183
      RRM1_La; RNA recognition motif 1 in La autoantigen (La or LARP3) and similar proteins

    2. XM_038649190.1 → XP_038505118.1  lupus La protein

      Conserved Domains (3) summary
      cd08028
      Location:10 → 91
      LARP_3; La RNA-binding domain of La-related protein 3
      pfam08777
      Location:231 → 334
      RRM_3; RNA binding motif
      cd12291
      Location:112 → 183
      RRM1_La; RNA recognition motif 1 in La autoantigen (La or LARP3) and similar proteins

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049257.1 Alternate UU_Cfam_GSD_1.0

      Range
      14770849..14782579
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038584773.1 → XP_038440701.1  lupus La protein

      UniProtKB/TrEMBL
      A0A8C0MPL8, A0A8C0QUD0, A0A8C0TUD6, A0A8I3PZQ3, A0A8I3S7X5
      Conserved Domains (3) summary
      cd08028
      Location:10 → 91
      LARP_3; La RNA-binding domain of La-related protein 3
      pfam08777
      Location:231 → 334
      RRM_3; RNA binding motif
      cd12291
      Location:112 → 183
      RRM1_La; RNA recognition motif 1 in La autoantigen (La or LARP3) and similar proteins

    2. XM_038584774.1 → XP_038440702.1  lupus La protein

      UniProtKB/TrEMBL
      A0A8C0MPL8, A0A8C0QUD0, A0A8C0TUD6, A0A8I3PZQ3, A0A8I3S7X5
      Conserved Domains (3) summary
      cd08028
      Location:10 → 91
      LARP_3; La RNA-binding domain of La-related protein 3
      pfam08777
      Location:231 → 334
      RRM_3; RNA binding motif
      cd12291
      Location:112 → 183
      RRM1_La; RNA recognition motif 1 in La autoantigen (La or LARP3) and similar proteins

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006618.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      14477215..14488515
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_535952.7 → XP_535952.2  lupus La protein

      UniProtKB/TrEMBL
      A0A8C0MPL8, A0A8C0QUD0, A0A8C0TUD6, A0A8I3PZQ3, A0A8I3S7X5
      Conserved Domains (3) summary
      cd08028
      Location:10 → 91
      LARP_3; La RNA-binding domain of La-related protein 3
      pfam08777
      Location:231 → 334
      RRM_3; RNA binding motif
      cd12291
      Location:112 → 183
      RRM1_La; RNA recognition motif 1 in La autoantigen (La or LARP3) and similar proteins

    2. XM_022414678.2 → XP_022270386.1  lupus La protein

      UniProtKB/TrEMBL
      A0A8C0MPL8, A0A8C0QUD0, A0A8C0TUD6, A0A8I3PZQ3, A0A8I3S7X5
      Conserved Domains (3) summary
      cd08028
      Location:10 → 91
      LARP_3; La RNA-binding domain of La-related protein 3
      pfam08777
      Location:231 → 334
      RRM_3; RNA binding motif
      cd12291
      Location:112 → 183
      RRM1_La; RNA recognition motif 1 in La autoantigen (La or LARP3) and similar proteins
    Nucleotide Protein
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