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    KPNA4 karyopherin subunit alpha 4 [ Canis lupus familiaris (dog) ]

    Gene ID: 478680, updated on 17-Aug-2024

    Summary

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    Official Symbol
    KPNA4provided by VGNC
    Official Full Name
    karyopherin subunit alpha 4provided by VGNC
    Primary source
    VGNC:VGNC:42502
    See related
    Ensembl:ENSCAFG00845027853
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Orthologs
    human mouse all
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    Genomic context

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    See KPNA4 in Genome Data Viewer
    Location:
    chromosome: 34
    Exon count:
    18
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 34 NC_051838.1 (26605763..26671157, complement)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 34 NC_006616.4 (30591206..30656539, complement)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 34 NC_049255.1 (26735945..26801570, complement)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 34 NC_049294.1 (26535571..26600913, complement)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 34 NC_049775.1 (26495988..26561625, complement)

    Chromosome 34 - NC_051838.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC106558222 Neighboring gene tripartite motif containing 59 Neighboring gene uncharacterized LOC119867514 Neighboring gene small Cajal body-specific RNA 7 Neighboring gene malate dehydrogenase, mitochondrial-like Neighboring gene ADP-ribosylation factor-like protein 14 Neighboring gene ARF like GTPase 14

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables nuclear import signal receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables nuclear localization sequence binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in NLS-bearing protein import into nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nucleoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    importin subunit alpha-3

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051838.1 Reference ROS_Cfam_1.0

      Range
      26605763..26671157 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038445941.1 → XP_038301869.1  importin subunit alpha-3

      UniProtKB/TrEMBL
      A0A8C0NP75, A0A8C0RKC2, A0A8I3QF14
      Conserved Domains (2) summary
      COG5064
      Location:11 → 513
      SRP1; Karyopherin (importin) alpha [Intracellular trafficking and secretion]
      sd00043
      Location:279 → 311
      ARM; armadillo repeat [structural motif]

    2. XM_038445940.1 → XP_038301868.1  importin subunit alpha-3

      UniProtKB/TrEMBL
      A0A8C0NP75, A0A8C0RKC2, A0A8I3QF14
      Related
      ENSCAFP00845038634.1, ENSCAFT00845049232.1
      Conserved Domains (2) summary
      COG5064
      Location:11 → 513
      SRP1; Karyopherin (importin) alpha [Intracellular trafficking and secretion]
      sd00043
      Location:279 → 311
      ARM; armadillo repeat [structural motif]

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049294.1 Alternate UMICH_Zoey_3.1

      Range
      26535571..26600913 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038520136.1 → XP_038376064.1  importin subunit alpha-3

      Conserved Domains (2) summary
      COG5064
      Location:11 → 513
      SRP1; Karyopherin (importin) alpha [Intracellular trafficking and secretion]
      sd00043
      Location:279 → 311
      ARM; armadillo repeat [structural motif]

    2. XM_038520135.1 → XP_038376063.1  importin subunit alpha-3

      Conserved Domains (2) summary
      COG5064
      Location:11 → 513
      SRP1; Karyopherin (importin) alpha [Intracellular trafficking and secretion]
      sd00043
      Location:279 → 311
      ARM; armadillo repeat [structural motif]

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049775.1 Alternate UNSW_CanFamBas_1.0

      Range
      26495988..26561625 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038648179.1 → XP_038504107.1  importin subunit alpha-3

      Conserved Domains (2) summary
      COG5064
      Location:11 → 513
      SRP1; Karyopherin (importin) alpha [Intracellular trafficking and secretion]
      sd00043
      Location:279 → 311
      ARM; armadillo repeat [structural motif]

    2. XM_038648178.1 → XP_038504106.1  importin subunit alpha-3

      Conserved Domains (2) summary
      COG5064
      Location:11 → 513
      SRP1; Karyopherin (importin) alpha [Intracellular trafficking and secretion]
      sd00043
      Location:279 → 311
      ARM; armadillo repeat [structural motif]

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049255.1 Alternate UU_Cfam_GSD_1.0

      Range
      26735945..26801570 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038583766.1 → XP_038439694.1  importin subunit alpha-3

      UniProtKB/TrEMBL
      A0A8C0NP75, A0A8C0RKC2, A0A8I3QF14
      Conserved Domains (2) summary
      COG5064
      Location:11 → 513
      SRP1; Karyopherin (importin) alpha [Intracellular trafficking and secretion]
      sd00043
      Location:279 → 311
      ARM; armadillo repeat [structural motif]

    2. XM_038583765.1 → XP_038439693.1  importin subunit alpha-3

      UniProtKB/TrEMBL
      A0A8C0NP75, A0A8C0RKC2, A0A8I3QF14
      Conserved Domains (2) summary
      COG5064
      Location:11 → 513
      SRP1; Karyopherin (importin) alpha [Intracellular trafficking and secretion]
      sd00043
      Location:279 → 311
      ARM; armadillo repeat [structural motif]

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006616.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      30591206..30656539 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_022414075.2 → XP_022269783.1  importin subunit alpha-3

      UniProtKB/TrEMBL
      A0A8C0NP75, A0A8C0RKC2, A0A8I3QF14
      Conserved Domains (2) summary
      COG5064
      Location:11 → 513
      SRP1; Karyopherin (importin) alpha [Intracellular trafficking and secretion]
      sd00043
      Location:279 → 311
      ARM; armadillo repeat [structural motif]

    2. XM_005639865.4 → XP_005639922.1  importin subunit alpha-3

      See identical proteins and their annotated locations for XP_005639922.1

      UniProtKB/TrEMBL
      A0A8C0NP75, A0A8C0RKC2, A0A8I3QF14
      Conserved Domains (2) summary
      COG5064
      Location:11 → 513
      SRP1; Karyopherin (importin) alpha [Intracellular trafficking and secretion]
      sd00043
      Location:279 → 311
      ARM; armadillo repeat [structural motif]
    Nucleotide Protein
    Heading Accession and Version

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