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    RFC4 replication factor C subunit 4 [ Canis lupus familiaris (dog) ]

    Gene ID: 478667, updated on 17-Aug-2024

    Summary

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    Official Symbol
    RFC4provided by VGNC
    Official Full Name
    replication factor C subunit 4provided by VGNC
    Primary source
    VGNC:VGNC:45495
    See related
    Ensembl:ENSCAFG00845021789
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Orthologs
    human mouse all
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    Genomic context

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    See RFC4 in Genome Data Viewer
    Location:
    chromosome: 34
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 34 NC_051838.1 (19272394..19288876, complement)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 34 NC_006616.4 (23446502..23462817, complement)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 34 NC_049255.1 (19531570..19547898, complement)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 34 NC_049294.1 (19303693..19320012, complement)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 34 NC_049775.1 (19303699..19320013, complement)

    Chromosome 34 - NC_051838.1Genomic Context describing neighboring genes Neighboring gene small nucleolar RNA SNORA63 Neighboring gene small nucleolar RNA SNORA4 Neighboring gene eukaryotic translation initiation factor 4A2 Neighboring gene adiponectin, C1Q and collagen domain containing Neighboring gene uncharacterized LOC119867406 Neighboring gene ST6 beta-galactoside alpha-2,6-sialyltransferase 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables ATP hydrolysis activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables DNA clamp loader activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in DNA repair IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in DNA-templated DNA replication IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of DNA replication factor C complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    replication factor C subunit 4

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051838.1 Reference ROS_Cfam_1.0

      Range
      19272394..19288876 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038445826.1 → XP_038301754.1  replication factor C subunit 4 isoform X2

      UniProtKB/TrEMBL
      A0A8C0NVT2, A0A8I3S581
      Conserved Domains (1) summary
      PRK00440
      Location:38 → 305
      rfc; replication factor C small subunit; Reviewed

    2. XM_038445824.1 → XP_038301752.1  replication factor C subunit 4 isoform X1

      UniProtKB/TrEMBL
      A0A8C0NVT2, A0A8C0QW47, A0A8C0T1X4, A0A8I3PDB8, A0A8I3S581
      Related
      ENSCAFP00845030103.1, ENSCAFT00845038451.1
      Conserved Domains (1) summary
      PRK00440
      Location:38 → 353
      rfc; replication factor C small subunit; Reviewed

    3. XM_038445825.1 → XP_038301753.1  replication factor C subunit 4 isoform X1

      UniProtKB/TrEMBL
      A0A8C0NVT2, A0A8C0QW47, A0A8C0T1X4, A0A8I3PDB8, A0A8I3S581
      Conserved Domains (1) summary
      PRK00440
      Location:38 → 353
      rfc; replication factor C small subunit; Reviewed

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049294.1 Alternate UMICH_Zoey_3.1

      Range
      19303693..19320012 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038520023.1 → XP_038375951.1  replication factor C subunit 4 isoform X2

      Conserved Domains (1) summary
      PRK00440
      Location:38 → 305
      rfc; replication factor C small subunit; Reviewed

    2. XM_038520021.1 → XP_038375949.1  replication factor C subunit 4 isoform X1

      Conserved Domains (1) summary
      PRK00440
      Location:38 → 353
      rfc; replication factor C small subunit; Reviewed

    3. XM_038520022.1 → XP_038375950.1  replication factor C subunit 4 isoform X1

      Conserved Domains (1) summary
      PRK00440
      Location:38 → 353
      rfc; replication factor C small subunit; Reviewed

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049775.1 Alternate UNSW_CanFamBas_1.0

      Range
      19303699..19320013 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038648065.1 → XP_038503993.1  replication factor C subunit 4 isoform X2

      Conserved Domains (1) summary
      PRK00440
      Location:38 → 305
      rfc; replication factor C small subunit; Reviewed

    2. XM_038648063.1 → XP_038503991.1  replication factor C subunit 4 isoform X1

      Conserved Domains (1) summary
      PRK00440
      Location:38 → 353
      rfc; replication factor C small subunit; Reviewed

    3. XM_038648064.1 → XP_038503992.1  replication factor C subunit 4 isoform X1

      Conserved Domains (1) summary
      PRK00440
      Location:38 → 353
      rfc; replication factor C small subunit; Reviewed

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049255.1 Alternate UU_Cfam_GSD_1.0

      Range
      19531570..19547898 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038583648.1 → XP_038439576.1  replication factor C subunit 4 isoform X2

      UniProtKB/TrEMBL
      A0A8C0NVT2, A0A8I3S581
      Conserved Domains (1) summary
      PRK00440
      Location:38 → 305
      rfc; replication factor C small subunit; Reviewed

    2. XM_038583646.1 → XP_038439574.1  replication factor C subunit 4 isoform X1

      UniProtKB/TrEMBL
      A0A8C0NVT2, A0A8C0QW47, A0A8C0T1X4, A0A8I3PDB8, A0A8I3S581
      Conserved Domains (1) summary
      PRK00440
      Location:38 → 353
      rfc; replication factor C small subunit; Reviewed

    3. XM_038583647.1 → XP_038439575.1  replication factor C subunit 4 isoform X1

      UniProtKB/TrEMBL
      A0A8C0NVT2, A0A8C0QW47, A0A8C0T1X4, A0A8I3PDB8, A0A8I3S581
      Conserved Domains (1) summary
      PRK00440
      Location:38 → 353
      rfc; replication factor C small subunit; Reviewed

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006616.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      23446502..23462817 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_022414074.2 → XP_022269782.1  replication factor C subunit 4 isoform X2

      UniProtKB/TrEMBL
      A0A8C0NVT2, A0A8I3S581
      Conserved Domains (1) summary
      PRK00440
      Location:38 → 305
      rfc; replication factor C small subunit; Reviewed

    2. XM_535837.7 → XP_535837.1  replication factor C subunit 4 isoform X1

      UniProtKB/TrEMBL
      A0A8C0NVT2, A0A8C0QW47, A0A8C0T1X4, A0A8I3PDB8, A0A8I3S581
      Conserved Domains (1) summary
      PRK00440
      Location:38 → 353
      rfc; replication factor C small subunit; Reviewed

    3. XM_022414073.2 → XP_022269781.1  replication factor C subunit 4 isoform X1

      UniProtKB/TrEMBL
      A0A8C0NVT2, A0A8C0QW47, A0A8C0T1X4, A0A8I3PDB8, A0A8I3S581
      Conserved Domains (1) summary
      PRK00440
      Location:38 → 353
      rfc; replication factor C small subunit; Reviewed
    Nucleotide Protein
    Heading Accession and Version

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