USP13 ubiquitin specific peptidase 13 [Canis lupus familiaris (dog)] - Gene

Summary

Official Symbol: USP13provided by VGNC
Official Full Name: ubiquitin specific peptidase 13provided by VGNC
Primary source: VGNC:VGNC:49638
See related: Ensembl:ENSCAFG00845016860
Gene type: protein coding
RefSeq status: MODEL
Organism: Canis lupus familiaris (sub-species: familiaris)
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 34

Exon count:: 24

Annotation release	Status	Assembly	Chr	Location
106	current	ROS_Cfam_1.0 (GCF_014441545.1)	34	NC_051838.1 (12957093..13074094)
106	current	Dog10K_Boxer_Tasha (GCF_000002285.5)	34	NC_006616.4 (17200915..17303172)
106	current	UU_Cfam_GSD_1.0 (GCF_011100685.1)	34	NC_049255.1 (13230757..13347935)
106	current	UMICH_Zoey_3.1 (GCF_005444595.1)	34	NC_049294.1 (13008227..13125027)
106	current	UNSW_CanFamBas_1.0 (GCF_013276365.1)	34	NC_049775.1 (12990863..13107688)

Chromosome 34 - NC_051838.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

FH2776 (e-PCR)
- UniSTS:263649

Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables cysteine-type deubiquitinase activity	IEA Inferred from Electronic Annotation more info	PubMed
enables protein binding	IEA Inferred from Electronic Annotation more info	PubMed
enables zinc ion binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in protein deubiquitination	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: ubiquitin carboxyl-terminal hydrolase 13

Names: ubiquitin specific peptidase 13 (isopeptidase T-3)

XP_038301541.1

EC 3.1.2.15

EC 3.4.19.12

XP_038301542.1

EC 3.1.2.15

EC 3.4.19.12

XP_038301543.1

EC 3.1.2.15

EC 3.4.19.12

XP_038301544.1

EC 3.1.2.15

EC 3.4.19.12

XP_038318806.1

EC 3.1.2.15

EC 3.4.19.12

XP_038318807.1

EC 3.1.2.15

EC 3.4.19.12

XP_038318808.1

EC 3.1.2.15

EC 3.4.19.12

XP_038318809.1

EC 3.1.2.15

EC 3.4.19.12

XP_038375721.1

EC 3.1.2.15

EC 3.4.19.12

XP_038375722.1

EC 3.1.2.15

EC 3.4.19.12

XP_038375723.1

EC 3.1.2.15

EC 3.4.19.12

XP_038375724.1

EC 3.1.2.15

EC 3.4.19.12

XP_038439361.1

EC 3.1.2.15

EC 3.4.19.12

XP_038439362.1

EC 3.1.2.15

EC 3.4.19.12

XP_038439363.1

EC 3.1.2.15

EC 3.4.19.12

XP_038439364.1

EC 3.1.2.15

EC 3.4.19.12

XP_038503773.1

EC 3.1.2.15

EC 3.4.19.12

XP_038503774.1

EC 3.1.2.15

EC 3.4.19.12

XP_038503775.1

EC 3.1.2.15

EC 3.4.19.12

XP_038503777.1

EC 3.1.2.15

EC 3.4.19.12

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

NC_051838.1 Reference ROS_Cfam_1.0

Range

12957093..13074094

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038445613.1 → XP_038301541.1 ubiquitin carboxyl-terminal hydrolase 13 isoform X1

UniProtKB/TrEMBL

A0A8C0LH16, A0A8C0RMN4, A0A8C0TAK8, A0A8I3NY77

Related

ENSCAFP00845023578.1, ENSCAFT00845030056.1

Conserved Domains (2) summary

COG5207
Location:30 → 860

UBP14; Uncharacterized Zn-finger protein, UBP-type [General function prediction only]

cd02658
Location:337 → 858

Peptidase_C19B; A subfamily of Peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl ...
XM_038445614.1 → XP_038301542.1 ubiquitin carboxyl-terminal hydrolase 13 isoform X2

UniProtKB/TrEMBL

A0A8C0RMN4

Conserved Domains (2) summary

COG5207
Location:12 → 816

UBP14; Uncharacterized Zn-finger protein, UBP-type [General function prediction only]

cd02658
Location:293 → 814

Peptidase_C19B; A subfamily of Peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl ...
XM_038445615.1 → XP_038301543.1 ubiquitin carboxyl-terminal hydrolase 13 isoform X3

UniProtKB/TrEMBL

A0A8C0NRR8

Conserved Domains (2) summary

COG5207
Location:94 → 795

UBP14; Uncharacterized Zn-finger protein, UBP-type [General function prediction only]

cd02658
Location:272 → 793

Peptidase_C19B; A subfamily of Peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl ...
XM_038445616.1 → XP_038301544.1 ubiquitin carboxyl-terminal hydrolase 13 isoform X4

UniProtKB/TrEMBL

A0A8C0NRR8

Conserved Domains (2) summary

COG5207
Location:7 → 702

UBP14; Uncharacterized Zn-finger protein, UBP-type [General function prediction only]

cd02658
Location:179 → 700

Peptidase_C19B; A subfamily of Peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl ...

Alternate UMICH_Zoey_3.1

Genomic

NC_049294.1 Alternate UMICH_Zoey_3.1

Range

13008227..13125027

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038519793.1 → XP_038375721.1 ubiquitin carboxyl-terminal hydrolase 13 isoform X1

Conserved Domains (2) summary

COG5207
Location:30 → 860

UBP14; Uncharacterized Zn-finger protein, UBP-type [General function prediction only]

cd02658
Location:337 → 858

Peptidase_C19B; A subfamily of Peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl ...
XM_038519794.1 → XP_038375722.1 ubiquitin carboxyl-terminal hydrolase 13 isoform X2

Conserved Domains (2) summary

COG5207
Location:12 → 816

UBP14; Uncharacterized Zn-finger protein, UBP-type [General function prediction only]

cd02658
Location:293 → 814

Peptidase_C19B; A subfamily of Peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl ...
XM_038519795.1 → XP_038375723.1 ubiquitin carboxyl-terminal hydrolase 13 isoform X3

Conserved Domains (2) summary

COG5207
Location:94 → 795

UBP14; Uncharacterized Zn-finger protein, UBP-type [General function prediction only]

cd02658
Location:272 → 793

Peptidase_C19B; A subfamily of Peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl ...
XM_038519796.1 → XP_038375724.1 ubiquitin carboxyl-terminal hydrolase 13 isoform X4

Conserved Domains (2) summary

COG5207
Location:7 → 702

UBP14; Uncharacterized Zn-finger protein, UBP-type [General function prediction only]

cd02658
Location:179 → 700

Peptidase_C19B; A subfamily of Peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl ...

Alternate UNSW_CanFamBas_1.0

Genomic

NC_049775.1 Alternate UNSW_CanFamBas_1.0

Range

12990863..13107688

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038647845.1 → XP_038503773.1 ubiquitin carboxyl-terminal hydrolase 13 isoform X1

Conserved Domains (2) summary

COG5207
Location:30 → 860

UBP14; Uncharacterized Zn-finger protein, UBP-type [General function prediction only]

cd02658
Location:337 → 858

Peptidase_C19B; A subfamily of Peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl ...
XM_038647846.1 → XP_038503774.1 ubiquitin carboxyl-terminal hydrolase 13 isoform X2

Conserved Domains (2) summary

COG5207
Location:12 → 816

UBP14; Uncharacterized Zn-finger protein, UBP-type [General function prediction only]

cd02658
Location:293 → 814

Peptidase_C19B; A subfamily of Peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl ...
XM_038647847.1 → XP_038503775.1 ubiquitin carboxyl-terminal hydrolase 13 isoform X3

Conserved Domains (2) summary

COG5207
Location:94 → 795

UBP14; Uncharacterized Zn-finger protein, UBP-type [General function prediction only]

cd02658
Location:272 → 793

Peptidase_C19B; A subfamily of Peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl ...
XM_038647849.1 → XP_038503777.1 ubiquitin carboxyl-terminal hydrolase 13 isoform X4

Conserved Domains (2) summary

COG5207
Location:7 → 702

UBP14; Uncharacterized Zn-finger protein, UBP-type [General function prediction only]

cd02658
Location:179 → 700

Peptidase_C19B; A subfamily of Peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl ...

Alternate UU_Cfam_GSD_1.0

Genomic

NC_049255.1 Alternate UU_Cfam_GSD_1.0

Range

13230757..13347935

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038583433.1 → XP_038439361.1 ubiquitin carboxyl-terminal hydrolase 13 isoform X1

UniProtKB/TrEMBL

A0A8C0LH16, A0A8C0RMN4, A0A8C0TAK8, A0A8I3NY77

Conserved Domains (2) summary

COG5207
Location:30 → 860

UBP14; Uncharacterized Zn-finger protein, UBP-type [General function prediction only]

cd02658
Location:337 → 858

Peptidase_C19B; A subfamily of Peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl ...
XM_038583434.1 → XP_038439362.1 ubiquitin carboxyl-terminal hydrolase 13 isoform X2

UniProtKB/TrEMBL

A0A8C0RMN4

Conserved Domains (2) summary

COG5207
Location:12 → 816

UBP14; Uncharacterized Zn-finger protein, UBP-type [General function prediction only]

cd02658
Location:293 → 814

Peptidase_C19B; A subfamily of Peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl ...
XM_038583435.1 → XP_038439363.1 ubiquitin carboxyl-terminal hydrolase 13 isoform X3

UniProtKB/TrEMBL

A0A8C0NRR8

Conserved Domains (2) summary

COG5207
Location:94 → 795

UBP14; Uncharacterized Zn-finger protein, UBP-type [General function prediction only]

cd02658
Location:272 → 793

Peptidase_C19B; A subfamily of Peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl ...
XM_038583436.1 → XP_038439364.1 ubiquitin carboxyl-terminal hydrolase 13 isoform X4

UniProtKB/TrEMBL

A0A8C0NRR8

Conserved Domains (2) summary

COG5207
Location:7 → 702

UBP14; Uncharacterized Zn-finger protein, UBP-type [General function prediction only]

cd02658
Location:179 → 700

Peptidase_C19B; A subfamily of Peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl ...

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

NC_006616.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

Range

17200915..17303172

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038462878.1 → XP_038318806.1 ubiquitin carboxyl-terminal hydrolase 13 isoform X5

UniProtKB/TrEMBL

A0A8I3NRV0, A0A8I3P199, A0A8P0PCT0, A0A8P0SG53

Conserved Domains (2) summary

COG5207
Location:30 → 794

UBP14; Uncharacterized Zn-finger protein, UBP-type [General function prediction only]

cd02658
Location:337 → 610

Peptidase_C19B; A subfamily of Peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl ...
XM_038462879.1 → XP_038318807.1 ubiquitin carboxyl-terminal hydrolase 13 isoform X6

UniProtKB/TrEMBL

A0A8I3P199, A0A8P0PCT0

Conserved Domains (2) summary

COG5207
Location:12 → 750

UBP14; Uncharacterized Zn-finger protein, UBP-type [General function prediction only]

cd02658
Location:293 → 566

Peptidase_C19B; A subfamily of Peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl ...
XM_038462880.1 → XP_038318808.1 ubiquitin carboxyl-terminal hydrolase 13 isoform X7

UniProtKB/TrEMBL

A0A8I3P199, A0A8P0PCT0

Conserved Domains (2) summary

COG5207
Location:94 → 729

UBP14; Uncharacterized Zn-finger protein, UBP-type [General function prediction only]

cd02658
Location:272 → 545

Peptidase_C19B; A subfamily of Peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl ...
XM_038462881.1 → XP_038318809.1 ubiquitin carboxyl-terminal hydrolase 13 isoform X8

UniProtKB/TrEMBL

A0A8C0NRR8

Conserved Domains (2) summary

COG5207
Location:7 → 636

UBP14; Uncharacterized Zn-finger protein, UBP-type [General function prediction only]

cd02658
Location:179 → 452

Peptidase_C19B; A subfamily of Peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl ...