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    COPS2 COP9 signalosome subunit 2 [ Canis lupus familiaris (dog) ]

    Gene ID: 478295, updated on 17-Aug-2024

    Summary

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    Official Symbol
    COPS2provided by VGNC
    Official Full Name
    COP9 signalosome subunit 2provided by VGNC
    Primary source
    VGNC:VGNC:39509
    See related
    Ensembl:ENSCAFG00845021829
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Orthologs
    human mouse all
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    Genomic context

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    See COPS2 in Genome Data Viewer
    Location:
    chromosome: 30
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 30 NC_051834.1 (15468434..15501493, complement)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 30 NC_006612.4 (15256236..15289340, complement)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 30 NC_049251.1 (15619268..15652382, complement)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 30 NC_049290.1 (15391942..15424988, complement)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 30 NC_049771.1 (15513371..15546462, complement)

    Chromosome 30 - NC_051834.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC119866831 Neighboring gene SECIS binding protein 2 like Neighboring gene galactokinase 2 Neighboring gene uncharacterized LOC111093398 Neighboring gene family with sequence similarity 227 member B Neighboring gene fibroblast growth factor 7

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in protein deneddylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of COP9 signalosome IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    COP9 signalosome complex subunit 2
    Names
    COP9 constitutive photomorphogenic homolog subunit 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051834.1 Reference ROS_Cfam_1.0

      Range
      15468434..15501493 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038442300.1 → XP_038298228.1  COP9 signalosome complex subunit 2 isoform X2

      UniProtKB/TrEMBL
      A0A8I3PM77
      Conserved Domains (2) summary
      COG5159
      Location:40 → 434
      RPN6; 26S proteasome regulatory complex component [Posttranslational modification, protein turnover, chaperones]
      pfam01399
      Location:309 → 413
      PCI; PCI domain

    2. XM_038442299.1 → XP_038298227.1  COP9 signalosome complex subunit 2 isoform X1

      UniProtKB/TrEMBL
      A0A8C0L4G6, A0A8C0Z205, A0A8I3PM77, A0A8P0NGK7
      Related
      ENSCAFP00845030161.1, ENSCAFT00845038521.1
      Conserved Domains (2) summary
      COG5159
      Location:40 → 441
      RPN6; 26S proteasome regulatory complex component [Posttranslational modification, protein turnover, chaperones]
      pfam01399
      Location:316 → 420
      PCI; PCI domain

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049290.1 Alternate UMICH_Zoey_3.1

      Range
      15391942..15424988 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038516747.1 → XP_038372675.1  COP9 signalosome complex subunit 2 isoform X2

      Conserved Domains (2) summary
      COG5159
      Location:40 → 434
      RPN6; 26S proteasome regulatory complex component [Posttranslational modification, protein turnover, chaperones]
      pfam01399
      Location:309 → 413
      PCI; PCI domain

    2. XM_038516746.1 → XP_038372674.1  COP9 signalosome complex subunit 2 isoform X1

      Conserved Domains (2) summary
      COG5159
      Location:40 → 441
      RPN6; 26S proteasome regulatory complex component [Posttranslational modification, protein turnover, chaperones]
      pfam01399
      Location:316 → 420
      PCI; PCI domain

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049771.1 Alternate UNSW_CanFamBas_1.0

      Range
      15513371..15546462 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038644679.1 → XP_038500607.1  COP9 signalosome complex subunit 2 isoform X2

      Conserved Domains (2) summary
      COG5159
      Location:40 → 434
      RPN6; 26S proteasome regulatory complex component [Posttranslational modification, protein turnover, chaperones]
      pfam01399
      Location:309 → 413
      PCI; PCI domain

    2. XM_038644678.1 → XP_038500606.1  COP9 signalosome complex subunit 2 isoform X1

      Conserved Domains (2) summary
      COG5159
      Location:40 → 441
      RPN6; 26S proteasome regulatory complex component [Posttranslational modification, protein turnover, chaperones]
      pfam01399
      Location:316 → 420
      PCI; PCI domain

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049251.1 Alternate UU_Cfam_GSD_1.0

      Range
      15619268..15652382 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038580386.1 → XP_038436314.1  COP9 signalosome complex subunit 2 isoform X2

      UniProtKB/TrEMBL
      A0A8I3PM77
      Conserved Domains (2) summary
      COG5159
      Location:40 → 434
      RPN6; 26S proteasome regulatory complex component [Posttranslational modification, protein turnover, chaperones]
      pfam01399
      Location:309 → 413
      PCI; PCI domain

    2. XM_038580385.1 → XP_038436313.1  COP9 signalosome complex subunit 2 isoform X1

      UniProtKB/TrEMBL
      A0A8C0L4G6, A0A8C0Z205, A0A8I3PM77, A0A8P0NGK7
      Conserved Domains (2) summary
      COG5159
      Location:40 → 441
      RPN6; 26S proteasome regulatory complex component [Posttranslational modification, protein turnover, chaperones]
      pfam01399
      Location:316 → 420
      PCI; PCI domain

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006612.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      15256236..15289340 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_535470.7 → XP_535470.1  COP9 signalosome complex subunit 2 isoform X2

      See identical proteins and their annotated locations for XP_535470.1

      UniProtKB/TrEMBL
      A0A8I3PM77
      Conserved Domains (2) summary
      COG5159
      Location:40 → 434
      RPN6; 26S proteasome regulatory complex component [Posttranslational modification, protein turnover, chaperones]
      pfam01399
      Location:309 → 413
      PCI; PCI domain

    2. XM_005638395.4 → XP_005638452.1  COP9 signalosome complex subunit 2 isoform X1

      See identical proteins and their annotated locations for XP_005638452.1

      UniProtKB/TrEMBL
      A0A8C0L4G6, A0A8C0Z205, A0A8I3PM77, A0A8P0NGK7
      Conserved Domains (2) summary
      COG5159
      Location:40 → 441
      RPN6; 26S proteasome regulatory complex component [Posttranslational modification, protein turnover, chaperones]
      pfam01399
      Location:316 → 420
      PCI; PCI domain
    Nucleotide Protein
    Heading Accession and Version

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